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The map label for this gene is trpB [H]

Identifier: 187934220

GI number: 187934220

Start: 2051175

End: 2052392

Strand: Reverse

Name: trpB [H]

Synonym: CLL_A1973

Alternate gene names: 187934220

Gene position: 2052392-2051175 (Counterclockwise)

Preceding gene: 187934950

Following gene: 187934353

Centisome position: 54.01

GC content: 34.65

Gene sequence:

>1218_bases
ATGGATTTTCGAACATATTTAAAGAAGTATCCAGATAAAAATGGTCGCTTTGGTCAATACGGTGGGGCATACTTAACAGC
TGAGCTAATTCCAGCTTTTGAGGAGATTGCTGATGCATATCAAACGATTTGTCATTCTTCACAGTTTATTAATGAACTTA
GAAGAATCCGTAAAGAATTTCAAGGTAGACCTACACCAGTTTATCATTGCGAAAGACTATCTAGAGCAATAGGAAATTGT
CAAATTTATTTAAAAAGAGAAGATTTAAATCATACAGGGGCACACAAATTAAATCATTGTATGGGTGAAGGATTACTTGC
TAAATTTATGGGAAAAAAGCGTTTGATTGCAGAAACAGGAGCAGGACAACATGGTGTGGCGCTTGCAACAGCTGCTGCAT
TTTTTGGATTGGAATGTGAAATTCATATGGGAGAAGTTGATATTGCAAAGCAAGCGCCAAATGTAACTAGGATGAAAATA
TTAGGAGCTAAAGTTGTTCCAGTAACACATGGTTTAAAAACTTTAAAAGAAGCTGTGGATTCTGCTTTTGATTCATATGC
TAAAAATTATAAGGATTCAATTTACTGCATAGGATCAGCCTTAGGTCCGCATCCATTTCCACTTATGGTAAGAGATTTCC
AAGCTGTTGTTGGTTATGAAGCTAAAGATCAATTTAAGGAAATGACAGGTTTTTTACCAGATGTAGTTACTGCTTGTGTA
GGCGGTGGAAGCAATGCTGCTGGAATGTTTATACCTTTTTTAGAGGAACCAGTTGATATAATTGGAATAGAACCATTAGG
TAGAGGCGAAAAATTAGGAGATCATGCTGCATCTATGAAATATGGAGAAAAAGGTGTTATGCATGGCTTTGAAAGTATAA
TGTTAAAAGATAAAAATGGTGATCCAGCACCAGTATATTCTATAGCCAGTGGACTTGATTATCCATCAGTTGGTCCTGAA
CATGCATTTTTAAGAGAATTAGGACGTGTAGATTATAAAGTTATAAATGATGAAGAGGCAATGGAAGCTTTCTTTAAATT
ATCAAGATATGAAGGAATTATACCTGCAATTGAAAGTTCACATGCTGTTGCATATGCAATGAAAAAAGCTGAAGAAATGA
AACAAGGATCTATTTTAGTTTGTTTGAGTGGACGTGGTGATAAAGACATTGATTATATTGTTGAACATTATGGATATGGA
GAACAATATTTTAAATAA

Upstream 100 bases:

>100_bases
ATGAGAGAAAATTGTAAATAAAAAGTATATATAGTATAATTTTATATGTAAATGTTTAGATAGATAAATTTAAACTTAAA
GCATATAAGGGGGAGTGTAA

Downstream 100 bases:

>100_bases
TAATTAAAATATAAAAAGGTGTTTCTTGTTTAAGACAAGAATGCCTTTTTTTGTGCATAAAAATTTTAAAATTAGTAATA
TGTTTACTAATTTATTATTA

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MDFRTYLKKYPDKNGRFGQYGGAYLTAELIPAFEEIADAYQTICHSSQFINELRRIRKEFQGRPTPVYHCERLSRAIGNC
QIYLKREDLNHTGAHKLNHCMGEGLLAKFMGKKRLIAETGAGQHGVALATAAAFFGLECEIHMGEVDIAKQAPNVTRMKI
LGAKVVPVTHGLKTLKEAVDSAFDSYAKNYKDSIYCIGSALGPHPFPLMVRDFQAVVGYEAKDQFKEMTGFLPDVVTACV
GGGSNAAGMFIPFLEEPVDIIGIEPLGRGEKLGDHAASMKYGEKGVMHGFESIMLKDKNGDPAPVYSIASGLDYPSVGPE
HAFLRELGRVDYKVINDEEAMEAFFKLSRYEGIIPAIESSHAVAYAMKKAEEMKQGSILVCLSGRGDKDIDYIVEHYGYG
EQYFK

Sequences:

>Translated_405_residues
MDFRTYLKKYPDKNGRFGQYGGAYLTAELIPAFEEIADAYQTICHSSQFINELRRIRKEFQGRPTPVYHCERLSRAIGNC
QIYLKREDLNHTGAHKLNHCMGEGLLAKFMGKKRLIAETGAGQHGVALATAAAFFGLECEIHMGEVDIAKQAPNVTRMKI
LGAKVVPVTHGLKTLKEAVDSAFDSYAKNYKDSIYCIGSALGPHPFPLMVRDFQAVVGYEAKDQFKEMTGFLPDVVTACV
GGGSNAAGMFIPFLEEPVDIIGIEPLGRGEKLGDHAASMKYGEKGVMHGFESIMLKDKNGDPAPVYSIASGLDYPSVGPE
HAFLRELGRVDYKVINDEEAMEAFFKLSRYEGIIPAIESSHAVAYAMKKAEEMKQGSILVCLSGRGDKDIDYIVEHYGYG
EQYFK
>Mature_405_residues
MDFRTYLKKYPDKNGRFGQYGGAYLTAELIPAFEEIADAYQTICHSSQFINELRRIRKEFQGRPTPVYHCERLSRAIGNC
QIYLKREDLNHTGAHKLNHCMGEGLLAKFMGKKRLIAETGAGQHGVALATAAAFFGLECEIHMGEVDIAKQAPNVTRMKI
LGAKVVPVTHGLKTLKEAVDSAFDSYAKNYKDSIYCIGSALGPHPFPLMVRDFQAVVGYEAKDQFKEMTGFLPDVVTACV
GGGSNAAGMFIPFLEEPVDIIGIEPLGRGEKLGDHAASMKYGEKGVMHGFESIMLKDKNGDPAPVYSIASGLDYPSVGPE
HAFLRELGRVDYKVINDEEAMEAFFKLSRYEGIIPAIESSHAVAYAMKKAEEMKQGSILVCLSGRGDKDIDYIVEHYGYG
EQYFK

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=380, Percent_Identity=48.4210526315789, Blast_Score=369, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6321412, Length=383, Percent_Identity=46.9973890339426, Blast_Score=352, Evalue=7e-98,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 44771; Mature: 44771

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFRTYLKKYPDKNGRFGQYGGAYLTAELIPAFEEIADAYQTICHSSQFINELRRIRKEF
CCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGRPTPVYHCERLSRAIGNCQIYLKREDLNHTGAHKLNHCMGEGLLAKFMGKKRLIAETG
CCCCCCHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCHHEEHHCC
AGQHGVALATAAAFFGLECEIHMGEVDIAKQAPNVTRMKILGAKVVPVTHGLKTLKEAVD
CCCCCHHHHHHHHHHCCEEEEEECCEEHHHCCCCCEEEEEECCEECHHHHHHHHHHHHHH
SAFDSYAKNYKDSIYCIGSALGPHPFPLMVRDFQAVVGYEAKDQFKEMTGFLPDVVTACV
HHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHH
GGGSNAAGMFIPFLEEPVDIIGIEPLGRGEKLGDHAASMKYGEKGVMHGFESIMLKDKNG
CCCCCCCCEECHHHHCCCCEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHEEECCCC
DPAPVYSIASGLDYPSVGPEHAFLRELGRVDYKVINDEEAMEAFFKLSRYEGIIPAIESS
CCCHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCC
HAVAYAMKKAEEMKQGSILVCLSGRGDKDIDYIVEHYGYGEQYFK
HHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCCCHHHCC
>Mature Secondary Structure
MDFRTYLKKYPDKNGRFGQYGGAYLTAELIPAFEEIADAYQTICHSSQFINELRRIRKEF
CCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGRPTPVYHCERLSRAIGNCQIYLKREDLNHTGAHKLNHCMGEGLLAKFMGKKRLIAETG
CCCCCCHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCHHEEHHCC
AGQHGVALATAAAFFGLECEIHMGEVDIAKQAPNVTRMKILGAKVVPVTHGLKTLKEAVD
CCCCCHHHHHHHHHHCCEEEEEECCEEHHHCCCCCEEEEEECCEECHHHHHHHHHHHHHH
SAFDSYAKNYKDSIYCIGSALGPHPFPLMVRDFQAVVGYEAKDQFKEMTGFLPDVVTACV
HHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHH
GGGSNAAGMFIPFLEEPVDIIGIEPLGRGEKLGDHAASMKYGEKGVMHGFESIMLKDKNG
CCCCCCCCEECHHHHCCCCEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHEEECCCC
DPAPVYSIASGLDYPSVGPEHAFLRELGRVDYKVINDEEAMEAFFKLSRYEGIIPAIESS
CCCHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCC
HAVAYAMKKAEEMKQGSILVCLSGRGDKDIDYIVEHYGYGEQYFK
HHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA