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The map label for this gene is lexA [H]

Identifier: 187934950

GI number: 187934950

Start: 2052472

End: 2054013

Strand: Reverse

Name: lexA [H]

Synonym: CLL_A1974

Alternate gene names: 187934950

Gene position: 2054013-2052472 (Counterclockwise)

Preceding gene: 187932758

Following gene: 187934220

Centisome position: 54.05

GC content: 25.81

Gene sequence:

>1542_bases
ATGCAACTTAATATAGAACAAAAAAGAATAATTGCAAATAAACCAAATGGTCATTCATTAATAAAAGGGGTAGCAGGTTC
TGGGAAAACTACTGTTGCAGTAAATAAAATTCCATTATTATTAAGACATTATTGTCCACTTAAAGATGACAAAGTACTTA
TGGTAACTTATAATAAATCACTAAAACAATATGTGTCAAATATATATGATAAAGTTAAAGATAAAGTTAATGTTCAGGTG
AATCTATTTGATGAGGATAATAGTTTGAAGTTATACGTTAAAAGAATTGATGATATACTTCTTGATTATTTTAATGCATA
CAAGAAACAGAATGATATAAATATAGACCTTGCTTCGCGTAAAGAATGTAAATATGAATTAATTAATGCCATAAACTTTA
TTGGTAATATCTATAAAGATGTAAAAATCATAGATTCTAAGTATCTTCAGTTTATTAAAGAAGAGATTATGTGGATAAAA
GCATGTAATTATATAGATCTTGAGGAATATCAGTTGGTTGATAGAATAGGAAGAATAAGTAATATAAATAATGATGGTCC
TCAAAAACTCAGAAAAAATTCAGAAAAGAGAAGAGCAATATTTGAGGTCTTGTTAAAATATAATAGTAATTTACAGAATA
TAAATAAAGTTGATTTTCAAGATATGGCACTACTAGCATTAAATCAAGCAAAACAATACCCTATTGAAAAGTATACTCAT
ATTTTAATAGATGAAAGTCAAGATTTAACTAGAGTTGAATTGGAATTTTTAAAGGCTTTGTATGATAAAAAACCATATTC
GAGTATAACATTTATTTCAGATGCAGCTCAAAGTATATACCATCAAGCTTGGTTAATAAAAAATCGTTCATTTGCCAGCT
TAGGATATGATATGACTGGTAAATCTAATTTATTAAGTAAGAATTATAGAACAACGGCTCAAATAGCTGAGGCAGCATTC
AGTTTAATTGATATTCATAAAGATTTATTACAAAATGACAACTTAGTTAAACCTAATTTGATAGACAAGCAAGGTGATTA
TCCAACCTATGAAAATTTTGAAAATAAATTTGAAGAATGTATATATATAGTAAATTTAATAAATGAAACTCTCAAAGAAG
GATATAAATTAAAAGATATAGTAATAATTGCTAGATTAAAAAAACAGTTAAAAGAATTTAGGAAATGTTTACAAGCTTAT
TATATACCATGTTCAATTTTTAATGATAATGATGAAATAAACTTTTCAGAAGATGAGGTAAAACTTGTAACTATGCACTC
TGTAAAAGGACTTGAATTTAAAGTTGTTATAATTGCAGGTCTAAATGCTAAAGTAATGCCACTATGTCCAGTTAAAAATG
AAGAAGAGGATATGGACATGCTAGAATTTAGAGAAAGAAAGTTACTTTATGTTGGAATGACAAGAGCTACTGAAAAATTA
TTTTTAACATCACATGGTATGCCTTCTAAATTTATTAGAGATATAGATGATAAATACTTAAGAATGAATATGGATAGTAA
TATGAGAGAAAATTGTAAATAA

Upstream 100 bases:

>100_bases
TTCACAATGAATCAAAACTTTACATAGCGTTACATAATATAGTACAATTAGTATATGTAATTTCCAAAAAATAGAAATAA
TTAGATAAAGAGGGGTAGAA

Downstream 100 bases:

>100_bases
AAAGTATATATAGTATAATTTTATATGTAAATGTTTAGATAGATAAATTTAAACTTAAAGCATATAAGGGGGAGTGTAAA
TGGATTTTCGAACATATTTA

Product: LexA repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MQLNIEQKRIIANKPNGHSLIKGVAGSGKTTVAVNKIPLLLRHYCPLKDDKVLMVTYNKSLKQYVSNIYDKVKDKVNVQV
NLFDEDNSLKLYVKRIDDILLDYFNAYKKQNDINIDLASRKECKYELINAINFIGNIYKDVKIIDSKYLQFIKEEIMWIK
ACNYIDLEEYQLVDRIGRISNINNDGPQKLRKNSEKRRAIFEVLLKYNSNLQNINKVDFQDMALLALNQAKQYPIEKYTH
ILIDESQDLTRVELEFLKALYDKKPYSSITFISDAAQSIYHQAWLIKNRSFASLGYDMTGKSNLLSKNYRTTAQIAEAAF
SLIDIHKDLLQNDNLVKPNLIDKQGDYPTYENFENKFEECIYIVNLINETLKEGYKLKDIVIIARLKKQLKEFRKCLQAY
YIPCSIFNDNDEINFSEDEVKLVTMHSVKGLEFKVVIIAGLNAKVMPLCPVKNEEEDMDMLEFRERKLLYVGMTRATEKL
FLTSHGMPSKFIRDIDDKYLRMNMDSNMRENCK

Sequences:

>Translated_513_residues
MQLNIEQKRIIANKPNGHSLIKGVAGSGKTTVAVNKIPLLLRHYCPLKDDKVLMVTYNKSLKQYVSNIYDKVKDKVNVQV
NLFDEDNSLKLYVKRIDDILLDYFNAYKKQNDINIDLASRKECKYELINAINFIGNIYKDVKIIDSKYLQFIKEEIMWIK
ACNYIDLEEYQLVDRIGRISNINNDGPQKLRKNSEKRRAIFEVLLKYNSNLQNINKVDFQDMALLALNQAKQYPIEKYTH
ILIDESQDLTRVELEFLKALYDKKPYSSITFISDAAQSIYHQAWLIKNRSFASLGYDMTGKSNLLSKNYRTTAQIAEAAF
SLIDIHKDLLQNDNLVKPNLIDKQGDYPTYENFENKFEECIYIVNLINETLKEGYKLKDIVIIARLKKQLKEFRKCLQAY
YIPCSIFNDNDEINFSEDEVKLVTMHSVKGLEFKVVIIAGLNAKVMPLCPVKNEEEDMDMLEFRERKLLYVGMTRATEKL
FLTSHGMPSKFIRDIDDKYLRMNMDSNMRENCK
>Mature_513_residues
MQLNIEQKRIIANKPNGHSLIKGVAGSGKTTVAVNKIPLLLRHYCPLKDDKVLMVTYNKSLKQYVSNIYDKVKDKVNVQV
NLFDEDNSLKLYVKRIDDILLDYFNAYKKQNDINIDLASRKECKYELINAINFIGNIYKDVKIIDSKYLQFIKEEIMWIK
ACNYIDLEEYQLVDRIGRISNINNDGPQKLRKNSEKRRAIFEVLLKYNSNLQNINKVDFQDMALLALNQAKQYPIEKYTH
ILIDESQDLTRVELEFLKALYDKKPYSSITFISDAAQSIYHQAWLIKNRSFASLGYDMTGKSNLLSKNYRTTAQIAEAAF
SLIDIHKDLLQNDNLVKPNLIDKQGDYPTYENFENKFEECIYIVNLINETLKEGYKLKDIVIIARLKKQLKEFRKCLQAY
YIPCSIFNDNDEINFSEDEVKLVTMHSVKGLEFKVVIIAGLNAKVMPLCPVKNEEEDMDMLEFRERKLLYVGMTRATEKL
FLTSHGMPSKFIRDIDDKYLRMNMDSNMRENCK

Specific function: Essential helicase. May act as a helicase in plasmid pT181 replication [H]

COG id: COG1974

COG function: function code KT; SOS-response transcriptional repressors (RecA-mediated autopeptidases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 uvrD-like helicase C-terminal domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005751
- InterPro:   IPR013986
- InterPro:   IPR014017
- InterPro:   IPR000212
- InterPro:   IPR014016 [H]

Pfam domain/function: PF00580 UvrD-helicase [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 59935; Mature: 59935

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLNIEQKRIIANKPNGHSLIKGVAGSGKTTVAVNKIPLLLRHYCPLKDDKVLMVTYNKS
CCCCCCHHHHCCCCCCCHHHHHHCCCCCCEEEEEHHHHHHHHHCCCCCCCCEEEEEECHH
LKQYVSNIYDKVKDKVNVQVNLFDEDNSLKLYVKRIDDILLDYFNAYKKQNDINIDLASR
HHHHHHHHHHHHHCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCC
KECKYELINAINFIGNIYKDVKIIDSKYLQFIKEEIMWIKACNYIDLEEYQLVDRIGRIS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHC
NINNDGPQKLRKNSEKRRAIFEVLLKYNSNLQNINKVDFQDMALLALNQAKQYPIEKYTH
CCCCCCHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHE
ILIDESQDLTRVELEFLKALYDKKPYSSITFISDAAQSIYHQAWLIKNRSFASLGYDMTG
EEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCC
KSNLLSKNYRTTAQIAEAAFSLIDIHKDLLQNDNLVKPNLIDKQGDYPTYENFENKFEEC
CCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
IYIVNLINETLKEGYKLKDIVIIARLKKQLKEFRKCLQAYYIPCSIFNDNDEINFSEDEV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCE
KLVTMHSVKGLEFKVVIIAGLNAKVMPLCPVKNEEEDMDMLEFRERKLLYVGMTRATEKL
EEEEEECCCCCEEEEEEEECCCCCEEEECCCCCCCCCHHHHHHHCCEEEEEEEHHHHHEE
FLTSHGMPSKFIRDIDDKYLRMNMDSNMRENCK
EEECCCCCHHHHHHCCHHHEEECCCCCHHHCCC
>Mature Secondary Structure
MQLNIEQKRIIANKPNGHSLIKGVAGSGKTTVAVNKIPLLLRHYCPLKDDKVLMVTYNKS
CCCCCCHHHHCCCCCCCHHHHHHCCCCCCEEEEEHHHHHHHHHCCCCCCCCEEEEEECHH
LKQYVSNIYDKVKDKVNVQVNLFDEDNSLKLYVKRIDDILLDYFNAYKKQNDINIDLASR
HHHHHHHHHHHHHCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCC
KECKYELINAINFIGNIYKDVKIIDSKYLQFIKEEIMWIKACNYIDLEEYQLVDRIGRIS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHC
NINNDGPQKLRKNSEKRRAIFEVLLKYNSNLQNINKVDFQDMALLALNQAKQYPIEKYTH
CCCCCCHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHE
ILIDESQDLTRVELEFLKALYDKKPYSSITFISDAAQSIYHQAWLIKNRSFASLGYDMTG
EEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCC
KSNLLSKNYRTTAQIAEAAFSLIDIHKDLLQNDNLVKPNLIDKQGDYPTYENFENKFEEC
CCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
IYIVNLINETLKEGYKLKDIVIIARLKKQLKEFRKCLQAYYIPCSIFNDNDEINFSEDEV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCE
KLVTMHSVKGLEFKVVIIAGLNAKVMPLCPVKNEEEDMDMLEFRERKLLYVGMTRATEKL
EEEEEECCCCCEEEEEEEECCCCCEEEECCCCCCCCCHHHHHHHCCEEEEEEEHHHHHEE
FLTSHGMPSKFIRDIDDKYLRMNMDSNMRENCK
EEECCCCCHHHHHHCCHHHEEECCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8232203 [H]