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The map label for this gene is yybE [H]

Identifier: 187934200

GI number: 187934200

Start: 2089896

End: 2090777

Strand: Reverse

Name: yybE [H]

Synonym: CLL_A2009

Alternate gene names: 187934200

Gene position: 2090777-2089896 (Counterclockwise)

Preceding gene: 187932354

Following gene: 187935390

Centisome position: 55.02

GC content: 25.85

Gene sequence:

>882_bases
ATGAATTTACAACAATTAGAGTATTTTATTGCAATAGCAAAAACTAAAAACTTTACAACAGCGTCAAACATGTTATCAGT
AACTCAGCCTGCACTTAGTAAATCTATATCAAAACTAGAAAAAGAATTAGAAACCTCTTTATTTGAAAGAGATGGACGTA
ATATTAAAATTAATAAGTTTGGAGAAGTGTTTTTAAAATATGCTGAATTAGCAATATTTAATATAGATAAAGGGATTGAA
GAATTAAAAGATATGCAAATAAGCAATGAAAAAAATATTTCAATTTCTTCTACTGAATGTATAGGAGCAACTTTTATACC
ATTTGTACTTAGTGATTTTTTACATATAAAATCTAATGTTAAGTTTGAATTTCATAATAGCTATCGAGAAGAAATTTTAA
TTGATTTAAAATATGGGAAAATAGATTTTGGTTTCTTTGATGATATTGAAGACATTGAAGAGTATTCAGATATTGAAGTT
ATATTAGTAAAAAAAGATAAGTATGTTTTAATTGTTCCAAAAGGTCATCATCTTTCTAATAAAACAGAAGTTTCACTAAA
GGACCTAAAGGATGAATTATTTGTTGTATTTAATAAAGGCTGCGATAATAAAAAAATATCCTATTCTGAGTTTATAGACT
ATACTCCTAAAATATCAGTACAGCCTAGTGAAGCGAGTATGTTGGGCACTTTAGTGGCAGCTGGAGCAGGGATAACAATA
GTTCCTAACACTCATATATTTAATACAAGCAAAATTTCTATATTAAATATAAAAGAAGATATAGGATATAAGACTATATA
TATGGGATGGAATAAAAAGAGTTTTGAATCTAAAATAATAAAAGAATTTAGAGATTACATAATAGATAGTTATTTGGAGT
AG

Upstream 100 bases:

>100_bases
GTTGGAATGATTGAAATTATAGCATTATAAAAAATATATATCAAACTAATATTATTCATATAATTATAACTTTTAGTTAT
ATATTAAAAGGAGAGCATAA

Downstream 100 bases:

>100_bases
AATTTTACTTATTATTTAAGTACTTCGGGACTATCATTACTTTCTGTTATGGAAAACATGATAAATTGGAGTAATAATAC
CCTATAATGTTATAAATAAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MNLQQLEYFIAIAKTKNFTTASNMLSVTQPALSKSISKLEKELETSLFERDGRNIKINKFGEVFLKYAELAIFNIDKGIE
ELKDMQISNEKNISISSTECIGATFIPFVLSDFLHIKSNVKFEFHNSYREEILIDLKYGKIDFGFFDDIEDIEEYSDIEV
ILVKKDKYVLIVPKGHHLSNKTEVSLKDLKDELFVVFNKGCDNKKISYSEFIDYTPKISVQPSEASMLGTLVAAGAGITI
VPNTHIFNTSKISILNIKEDIGYKTIYMGWNKKSFESKIIKEFRDYIIDSYLE

Sequences:

>Translated_293_residues
MNLQQLEYFIAIAKTKNFTTASNMLSVTQPALSKSISKLEKELETSLFERDGRNIKINKFGEVFLKYAELAIFNIDKGIE
ELKDMQISNEKNISISSTECIGATFIPFVLSDFLHIKSNVKFEFHNSYREEILIDLKYGKIDFGFFDDIEDIEEYSDIEV
ILVKKDKYVLIVPKGHHLSNKTEVSLKDLKDELFVVFNKGCDNKKISYSEFIDYTPKISVQPSEASMLGTLVAAGAGITI
VPNTHIFNTSKISILNIKEDIGYKTIYMGWNKKSFESKIIKEFRDYIIDSYLE
>Mature_293_residues
MNLQQLEYFIAIAKTKNFTTASNMLSVTQPALSKSISKLEKELETSLFERDGRNIKINKFGEVFLKYAELAIFNIDKGIE
ELKDMQISNEKNISISSTECIGATFIPFVLSDFLHIKSNVKFEFHNSYREEILIDLKYGKIDFGFFDDIEDIEEYSDIEV
ILVKKDKYVLIVPKGHHLSNKTEVSLKDLKDELFVVFNKGCDNKKISYSEFIDYTPKISVQPSEASMLGTLVAAGAGITI
VPNTHIFNTSKISILNIKEDIGYKTIYMGWNKKSFESKIIKEFRDYIIDSYLE

Specific function: Positive Regulatory Protein For The Cyn Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=289, Percent_Identity=24.2214532871972, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787879, Length=296, Percent_Identity=23.9864864864865, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1790399, Length=247, Percent_Identity=25.5060728744939, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788887, Length=293, Percent_Identity=23.8907849829352, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI145693105, Length=294, Percent_Identity=22.7891156462585, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI2367136, Length=246, Percent_Identity=21.9512195121951, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787601, Length=143, Percent_Identity=28.6713286713287, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1787806, Length=283, Percent_Identity=21.9081272084806, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1787530, Length=295, Percent_Identity=20.3389830508475, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1788481, Length=293, Percent_Identity=22.5255972696246, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788748, Length=243, Percent_Identity=19.3415637860082, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788296, Length=290, Percent_Identity=22.0689655172414, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI87081904, Length=207, Percent_Identity=24.6376811594203, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1789204, Length=245, Percent_Identity=20.8163265306122, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33594; Mature: 33594

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLQQLEYFIAIAKTKNFTTASNMLSVTQPALSKSISKLEKELETSLFERDGRNIKINKF
CCHHHEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHH
GEVFLKYAELAIFNIDKGIEELKDMQISNEKNISISSTECIGATFIPFVLSDFLHIKSNV
HHHHHHHHHHEEEEHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCC
KFEFHNSYREEILIDLKYGKIDFGFFDDIEDIEEYSDIEVILVKKDKYVLIVPKGHHLSN
EEEECCCCCEEEEEEEEECEEECCCCCCHHHHHHCCCEEEEEEECCCEEEEEECCCCCCC
KTEVSLKDLKDELFVVFNKGCDNKKISYSEFIDYTPKISVQPSEASMLGTLVAAGAGITI
CCEEHHHHHCCEEEEEEECCCCCCCCCHHHHHCCCCCEEECCCHHHHHHHHHHCCCCEEE
VPNTHIFNTSKISILNIKEDIGYKTIYMGWNKKSFESKIIKEFRDYIIDSYLE
ECCCEEECCCEEEEEEEHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLQQLEYFIAIAKTKNFTTASNMLSVTQPALSKSISKLEKELETSLFERDGRNIKINKF
CCHHHEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHH
GEVFLKYAELAIFNIDKGIEELKDMQISNEKNISISSTECIGATFIPFVLSDFLHIKSNV
HHHHHHHHHHEEEEHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCC
KFEFHNSYREEILIDLKYGKIDFGFFDDIEDIEEYSDIEVILVKKDKYVLIVPKGHHLSN
EEEECCCCCEEEEEEEEECEEECCCCCCHHHHHHCCCEEEEEEECCCEEEEEECCCCCCC
KTEVSLKDLKDELFVVFNKGCDNKKISYSEFIDYTPKISVQPSEASMLGTLVAAGAGITI
CCEEHHHHHCCEEEEEEECCCCCCCCCHHHHHCCCCCEEECCCHHHHHHHHHHCCCCEEE
VPNTHIFNTSKISILNIKEDIGYKTIYMGWNKKSFESKIIKEFRDYIIDSYLE
ECCCEEECCCEEEEEEEHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]