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The map label for this gene is fruR [H]

Identifier: 187933937

GI number: 187933937

Start: 2367843

End: 2368598

Strand: Reverse

Name: fruR [H]

Synonym: CLL_A2298

Alternate gene names: 187933937

Gene position: 2368598-2367843 (Counterclockwise)

Preceding gene: 187934341

Following gene: 187932782

Centisome position: 62.33

GC content: 27.38

Gene sequence:

>756_bases
ATGTTTACAGAGGAAAGATATAATATAATTCTTCAAGAATTAAAAGTAAAAGGAATAATTTCAGTTGTGGAACTAGTTAA
ACTACTAGAGGCTTCTGAATCTACAATAAGAAGAGATTTAAACAATCTTCACAATGAAGGATTGCTTAAAAAAATTCATG
GAGGAGCAACACTGTTAAATGAAGGTACAGCAAAACATGATTATAAAGTAAATGTTAGAAAATCATTAAATACAGATAAA
AAACTTGAAATAGCTAGATATGCAGCAAGTTTAATTGAAAATGGAGAGTTAATTTACTTAGATGCTGGAACAACAACAGA
AGCTATAATACCATTTATAGAAGCAAAAGATATAACAGTTGTTACTAATGCTATAGTTCATGCTAAGAATTTGCTAGAAA
AAAATATACGAACTTTAATACTAGGTGGAGAATTAAAAGCAGTTACTGAAGCAATTGTTGGTCCTATAACTGTAGAGCAT
TTAAAAAAATATAATTTTACAAAAGGTTTTTTTGGAACAAATGGTGTGAGTAATAAAAATGGTTATACAACTCCAGATGT
AAATGAAGCCATGGTAAAAGCAGAAGCAATAAAAAGATGTAATAAAGCATTTGTTTTATGTGATGAGTCTAAATTAGATG
AGGTTAGTTTTATAACTTTTGGAACAATAAAAGATGCAGAATTAATTACAAGTAGAATAAAAAATTCAGAGATTAGATAT
GATACTAATGTAATAGAGGTGAGTAAAAATGATTAA

Upstream 100 bases:

>100_bases
ATAGAATATAAGAATTTTTGAATGTTTTTAAATTATTTTGAATGAAAATGATTGATTTTTAAAAAGAAATAGTTTATTAT
AAAGATATGGAGTGGTGAGA

Downstream 100 bases:

>100_bases
TACAATAACTCTTAATCCTTCATTGGATTATATAGTAAAAGTTGATAATTTTAAAGTTGATTCATTAAATAGAAGTAATG
ATGAAGAAGTTTATGCAGGA

Product: lactose phosphotransferase system repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MFTEERYNIILQELKVKGIISVVELVKLLEASESTIRRDLNNLHNEGLLKKIHGGATLLNEGTAKHDYKVNVRKSLNTDK
KLEIARYAASLIENGELIYLDAGTTTEAIIPFIEAKDITVVTNAIVHAKNLLEKNIRTLILGGELKAVTEAIVGPITVEH
LKKYNFTKGFFGTNGVSNKNGYTTPDVNEAMVKAEAIKRCNKAFVLCDESKLDEVSFITFGTIKDAELITSRIKNSEIRY
DTNVIEVSKND

Sequences:

>Translated_251_residues
MFTEERYNIILQELKVKGIISVVELVKLLEASESTIRRDLNNLHNEGLLKKIHGGATLLNEGTAKHDYKVNVRKSLNTDK
KLEIARYAASLIENGELIYLDAGTTTEAIIPFIEAKDITVVTNAIVHAKNLLEKNIRTLILGGELKAVTEAIVGPITVEH
LKKYNFTKGFFGTNGVSNKNGYTTPDVNEAMVKAEAIKRCNKAFVLCDESKLDEVSFITFGTIKDAELITSRIKNSEIRY
DTNVIEVSKND
>Mature_251_residues
MFTEERYNIILQELKVKGIISVVELVKLLEASESTIRRDLNNLHNEGLLKKIHGGATLLNEGTAKHDYKVNVRKSLNTDK
KLEIARYAASLIENGELIYLDAGTTTEAIIPFIEAKDITVVTNAIVHAKNLLEKNIRTLILGGELKAVTEAIVGPITVEH
LKKYNFTKGFFGTNGVSNKNGYTTPDVNEAMVKAEAIKRCNKAFVLCDESKLDEVSFITFGTIKDAELITSRIKNSEIRY
DTNVIEVSKND

Specific function: Repressor Of The Glycerol-3-Phosphate Regulon. [C]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=227, Percent_Identity=31.2775330396476, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI226510968, Length=219, Percent_Identity=35.1598173515982, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787540, Length=236, Percent_Identity=30.5084745762712, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1789519, Length=217, Percent_Identity=29.9539170506912, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1787063, Length=234, Percent_Identity=32.9059829059829, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1789059, Length=218, Percent_Identity=32.1100917431193, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1790635, Length=243, Percent_Identity=27.5720164609054, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1788069, Length=226, Percent_Identity=28.3185840707965, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790753, Length=214, Percent_Identity=23.8317757009346, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI87082344, Length=246, Percent_Identity=23.5772357723577, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789170, Length=207, Percent_Identity=28.5024154589372, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27926; Mature: 27926

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTEERYNIILQELKVKGIISVVELVKLLEASESTIRRDLNNLHNEGLLKKIHGGATLLN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCEEEEC
EGTAKHDYKVNVRKSLNTDKKLEIARYAASLIENGELIYLDAGTTTEAIIPFIEAKDITV
CCCCCCCEEEEEHHHCCCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHEECCCCCHH
VTNAIVHAKNLLEKNIRTLILGGELKAVTEAIVGPITVEHLKKYNFTKGFFGTNGVSNKN
HHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCC
GYTTPDVNEAMVKAEAIKRCNKAFVLCDESKLDEVSFITFGTIKDAELITSRIKNSEIRY
CCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECCCCHHHHHHHHHCCCCEEE
DTNVIEVSKND
CCCEEEEECCC
>Mature Secondary Structure
MFTEERYNIILQELKVKGIISVVELVKLLEASESTIRRDLNNLHNEGLLKKIHGGATLLN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCEEEEC
EGTAKHDYKVNVRKSLNTDKKLEIARYAASLIENGELIYLDAGTTTEAIIPFIEAKDITV
CCCCCCCEEEEEHHHCCCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHEECCCCCHH
VTNAIVHAKNLLEKNIRTLILGGELKAVTEAIVGPITVEHLKKYNFTKGFFGTNGVSNKN
HHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCC
GYTTPDVNEAMVKAEAIKRCNKAFVLCDESKLDEVSFITFGTIKDAELITSRIKNSEIRY
CCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECCCCHHHHHHHHHCCCCEEE
DTNVIEVSKND
CCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]