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The map label for this gene is pfkB [H]

Identifier: 187932782

GI number: 187932782

Start: 2366948

End: 2367850

Strand: Reverse

Name: pfkB [H]

Synonym: CLL_A2297

Alternate gene names: 187932782

Gene position: 2367850-2366948 (Counterclockwise)

Preceding gene: 187933937

Following gene: 187932403

Centisome position: 62.31

GC content: 28.46

Gene sequence:

>903_bases
ATGATTAATACAATAACTCTTAATCCTTCATTGGATTATATAGTAAAAGTTGATAATTTTAAAGTTGATTCATTAAATAG
AAGTAATGATGAAGAAGTTTATGCAGGAGGAAAAGGAATAAATGTTTCTATAGTCTTAAATAATTTAGGCATAGATAACA
CGGCATTAGGGTATGTTGCAGGTTTTACAGGAAATGAAATAGAAAGACAAGTGAAAAATCATGGTGTTGACTGTGACTTT
ATAAAATTAAAAAATGGCATATCACGGATTAATGTAAAATTAAAAAGTGATGGAGAAACAGAAATAAATGGAGCAGGTCC
CAAAATTACAAATGATGATTTAAATAAATTATATGAAAAACTTTCTGACTTAAAAGAAGGAGACTATTTAATATTGTCAG
GTAGTATTCCAAATAGTGTACCAGATGATATTTATCAAAATATAATGGAAAAACTTTTAGAAAAGAAGGTAGAATTTATA
GTTGATGCAACAAAAGATTTACTGTTAAAGGTACTAAAGTACGAGCCATTTCTAATAAAACCTAATCATCATGAATTAGC
TGAAATGTTTAATGTTGAGCTGAAAAATGATGAAGATATAATAACTTATGGTAAGAAGCTTCAAGAAATGGGAGCAAAGA
ATGTATTAATTTCAATGGCTGGAGATGGAGCAATTTTATTATCTGAAAATGGAGAAACTATAAAAAGAGAAGTACCAAAG
GGAATATTAAAAAACTCAGTAGGAGCCGGAGATTCTATGGTGGCAGGTTTTTTAGCAGGATATCTTAAAAATAATGATAT
AAAAGAAGCATTTAAAATGGGAATTGCAACAGGTAGTGCAAGTGCATTTTCTGATGAATTAGCAACAAAAGAAGAAGTTG
AAAAACTATTATCTAAAATGTAA

Upstream 100 bases:

>100_bases
TTTATAACTTTTGGAACAATAAAAGATGCAGAATTAATTACAAGTAGAATAAAAAATTCAGAGATTAGATATGATACTAA
TGTAATAGAGGTGAGTAAAA

Downstream 100 bases:

>100_bases
AAATGCAAGGAGGAGTATTTAATGAGAATTGTTGATTTATTAAAAAAACAAGGCATTGAGTTAAACTTTAACCCATCTTC
TAAAGATGAATGTATTGAGA

Product: 1-phosphofructokinase

Products: NA

Alternate protein names: Fructose 1-phosphate kinase [H]

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MINTITLNPSLDYIVKVDNFKVDSLNRSNDEEVYAGGKGINVSIVLNNLGIDNTALGYVAGFTGNEIERQVKNHGVDCDF
IKLKNGISRINVKLKSDGETEINGAGPKITNDDLNKLYEKLSDLKEGDYLILSGSIPNSVPDDIYQNIMEKLLEKKVEFI
VDATKDLLLKVLKYEPFLIKPNHHELAEMFNVELKNDEDIITYGKKLQEMGAKNVLISMAGDGAILLSENGETIKREVPK
GILKNSVGAGDSMVAGFLAGYLKNNDIKEAFKMGIATGSASAFSDELATKEEVEKLLSKM

Sequences:

>Translated_300_residues
MINTITLNPSLDYIVKVDNFKVDSLNRSNDEEVYAGGKGINVSIVLNNLGIDNTALGYVAGFTGNEIERQVKNHGVDCDF
IKLKNGISRINVKLKSDGETEINGAGPKITNDDLNKLYEKLSDLKEGDYLILSGSIPNSVPDDIYQNIMEKLLEKKVEFI
VDATKDLLLKVLKYEPFLIKPNHHELAEMFNVELKNDEDIITYGKKLQEMGAKNVLISMAGDGAILLSENGETIKREVPK
GILKNSVGAGDSMVAGFLAGYLKNNDIKEAFKMGIATGSASAFSDELATKEEVEKLLSKM
>Mature_300_residues
MINTITLNPSLDYIVKVDNFKVDSLNRSNDEEVYAGGKGINVSIVLNNLGIDNTALGYVAGFTGNEIERQVKNHGVDCDF
IKLKNGISRINVKLKSDGETEINGAGPKITNDDLNKLYEKLSDLKEGDYLILSGSIPNSVPDDIYQNIMEKLLEKKVEFI
VDATKDLLLKVLKYEPFLIKPNHHELAEMFNVELKNDEDIITYGKKLQEMGAKNVLISMAGDGAILLSENGETIKREVPK
GILKNSVGAGDSMVAGFLAGYLKNNDIKEAFKMGIATGSASAFSDELATKEEVEKLLSKM

Specific function: Unknown

COG id: COG1105

COG function: function code G; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1788493, Length=264, Percent_Identity=33.7121212121212, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1788017, Length=306, Percent_Identity=26.4705882352941, Blast_Score=106, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022463
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR017583 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.56 [H]

Molecular weight: Translated: 32923; Mature: 32923

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINTITLNPSLDYIVKVDNFKVDSLNRSNDEEVYAGGKGINVSIVLNNLGIDNTALGYVA
CCEEEEECCCCCEEEEECCEEECCCCCCCCCEEEECCCCEEEEEEEECCCCCCCHHHEEE
GFTGNEIERQVKNHGVDCDFIKLKNGISRINVKLKSDGETEINGAGPKITNDDLNKLYEK
CCCCHHHHHHHHHCCCCEEEEEECCCCEEEEEEECCCCCCEECCCCCCCCCHHHHHHHHH
LSDLKEGDYLILSGSIPNSVPDDIYQNIMEKLLEKKVEFIVDATKDLLLKVLKYEPFLIK
HHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEC
PNHHELAEMFNVELKNDEDIITYGKKLQEMGAKNVLISMAGDGAILLSENGETIKREVPK
CCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCHHHHHHHH
GILKNSVGAGDSMVAGFLAGYLKNNDIKEAFKMGIATGSASAFSDELATKEEVEKLLSKM
HHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHCC
>Mature Secondary Structure
MINTITLNPSLDYIVKVDNFKVDSLNRSNDEEVYAGGKGINVSIVLNNLGIDNTALGYVA
CCEEEEECCCCCEEEEECCEEECCCCCCCCCEEEECCCCEEEEEEEECCCCCCCHHHEEE
GFTGNEIERQVKNHGVDCDFIKLKNGISRINVKLKSDGETEINGAGPKITNDDLNKLYEK
CCCCHHHHHHHHHCCCCEEEEEECCCCEEEEEEECCCCCCEECCCCCCCCCHHHHHHHHH
LSDLKEGDYLILSGSIPNSVPDDIYQNIMEKLLEKKVEFIVDATKDLLLKVLKYEPFLIK
HHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEC
PNHHELAEMFNVELKNDEDIITYGKKLQEMGAKNVLISMAGDGAILLSENGETIKREVPK
CCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCHHHHHHHH
GILKNSVGAGDSMVAGFLAGYLKNNDIKEAFKMGIATGSASAFSDELATKEEVEKLLSKM
HHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]