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The map label for this gene is resE [H]

Identifier: 187933865

GI number: 187933865

Start: 3750195

End: 3751625

Strand: Reverse

Name: resE [H]

Synonym: CLL_A3542

Alternate gene names: 187933865

Gene position: 3751625-3750195 (Counterclockwise)

Preceding gene: 187933158

Following gene: 187933812

Centisome position: 98.72

GC content: 22.08

Gene sequence:

>1431_bases
ATGAAGTCAATAAAACTAAAATTATTCTTTGGAATAACATTAATTTTAAGCATTTTTATAGTAGGTATAATTATTTATGG
ATCTATATTTAAGTCGTATTTTGAAAAAGAAAAATTAAAAGAAATGGAAATAATAATATTACAAATAGAATCAATTATAG
ATATAAATCATAATTCTGATTTTAAAGAAAGAGTAGATGAATTAGCAGATGAATACAATGTGCAAATAGATATAAAAGAT
AAAAATTTAGATAAAACCATATATGCTACACATGAAGGAAAAAATAATGGAGGATTTGGCCAAAATAAATTTAAAAACAT
TAAAGATATAGGAAGAATTAATGAAATAGATAGATTGATTCTTTATGATAAATCTACTGGTGTAAATTTTTTAACAGCAA
TAAAGGAACTTGATAATAACTTAAATAAAATAATTATAAAAACACCAATAAATATTATAGATGATGCAAAATCTAAATCC
ATAAATCTTTTAATATTAATATTTAGCCCTATTATATTTTTGATTATTGTCCTAACTTTAATATTTTCTACTAGATTTAC
AAAACCAATTATAGAGATTACTAAAAAAACTATGAAAATTAAAGAGTTAGATTTTAGTGAGGATATTGAGGTAAAAGGTA
AAGATGAAATATCAGTATTAAGCAAGAGCGTAAATAATCTTTCTCATAAAATTGAAAATACTTTAAGTGAATTGAATCAT
AAAAATTTAAAACTTGAAAGCATGATAAAAAAAGAAAAAGAAAATCAAAAATTAAGAAAAGAATTTGTTTCATCTGTATC
TCATGAATTAAAAAGTCCAATTACAGTTATTTTAGGTTATGCACAGGCTCTTTCTAGTGAAATTGTATCTTCAAATGAGG
ATAAAGAATATTATTTGGGTGTTATTAATGATGAGGCAGAAAGAATGCAAATAATAGTAAATGATCTTTTAGATTTATAT
AAATTAGAGTCAAATACATTTAGTTTAGAAATCAAAGAAGTAAATTTAGCTGATTTAGTTAAGAAAATAGTAAAAAAGAA
TTCATTACAATTCAAAAAAATGGATATTAATTTAATTTCTAAATTTGAATCTGCAATAGTAATTGCAGATGAAATAAGAT
TAGAACAAGCAATCCAAAATTATATTAATAATGCTTTAAATCATGTAGATAAGAAAAATATTATTAAGATAACTGTTTTA
TCATCAGGAATAATCAAGGTATTTAATAGTGGAAAAAATATTGAAGATAAGTATATAGAAAAAATATGGCATGGATTTGT
TAGAATTGATAAGGTTAGAAATTATAAAGAAAAAAGGGTTGGTCTTGGATTAACTATAGTAAGGGAAATAGTTAAACTTC
ATAAAGGACAGTATGGAATAGAAAATAAAGATCTTGGGGTTGAATTTTGGATTAAAATTCCTTTAATATAG

Upstream 100 bases:

>100_bases
CGGTAGACACTCATATTAATCGTTTAAGAAATAAACTAGAATATTATGCTGTTGATTTAAGAACTATAAGAGGTTTTGGA
TATAAGTTAGGTGAAGAATG

Downstream 100 bases:

>100_bases
TAAATTTATTATAAATGTTAAACAAGTATTATATTAATGTGACATAAATGTTACATTAACCAGTTAATATAAATATATAA
AATAAATTATATAAAAGATT

Product: membrane associated histidine kinase with hamp domain

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MKSIKLKLFFGITLILSIFIVGIIIYGSIFKSYFEKEKLKEMEIIILQIESIIDINHNSDFKERVDELADEYNVQIDIKD
KNLDKTIYATHEGKNNGGFGQNKFKNIKDIGRINEIDRLILYDKSTGVNFLTAIKELDNNLNKIIIKTPINIIDDAKSKS
INLLILIFSPIIFLIIVLTLIFSTRFTKPIIEITKKTMKIKELDFSEDIEVKGKDEISVLSKSVNNLSHKIENTLSELNH
KNLKLESMIKKEKENQKLRKEFVSSVSHELKSPITVILGYAQALSSEIVSSNEDKEYYLGVINDEAERMQIIVNDLLDLY
KLESNTFSLEIKEVNLADLVKKIVKKNSLQFKKMDINLISKFESAIVIADEIRLEQAIQNYINNALNHVDKKNIIKITVL
SSGIIKVFNSGKNIEDKYIEKIWHGFVRIDKVRNYKEKRVGLGLTIVREIVKLHKGQYGIENKDLGVEFWIKIPLI

Sequences:

>Translated_476_residues
MKSIKLKLFFGITLILSIFIVGIIIYGSIFKSYFEKEKLKEMEIIILQIESIIDINHNSDFKERVDELADEYNVQIDIKD
KNLDKTIYATHEGKNNGGFGQNKFKNIKDIGRINEIDRLILYDKSTGVNFLTAIKELDNNLNKIIIKTPINIIDDAKSKS
INLLILIFSPIIFLIIVLTLIFSTRFTKPIIEITKKTMKIKELDFSEDIEVKGKDEISVLSKSVNNLSHKIENTLSELNH
KNLKLESMIKKEKENQKLRKEFVSSVSHELKSPITVILGYAQALSSEIVSSNEDKEYYLGVINDEAERMQIIVNDLLDLY
KLESNTFSLEIKEVNLADLVKKIVKKNSLQFKKMDINLISKFESAIVIADEIRLEQAIQNYINNALNHVDKKNIIKITVL
SSGIIKVFNSGKNIEDKYIEKIWHGFVRIDKVRNYKEKRVGLGLTIVREIVKLHKGQYGIENKDLGVEFWIKIPLI
>Mature_476_residues
MKSIKLKLFFGITLILSIFIVGIIIYGSIFKSYFEKEKLKEMEIIILQIESIIDINHNSDFKERVDELADEYNVQIDIKD
KNLDKTIYATHEGKNNGGFGQNKFKNIKDIGRINEIDRLILYDKSTGVNFLTAIKELDNNLNKIIIKTPINIIDDAKSKS
INLLILIFSPIIFLIIVLTLIFSTRFTKPIIEITKKTMKIKELDFSEDIEVKGKDEISVLSKSVNNLSHKIENTLSELNH
KNLKLESMIKKEKENQKLRKEFVSSVSHELKSPITVILGYAQALSSEIVSSNEDKEYYLGVINDEAERMQIIVNDLLDLY
KLESNTFSLEIKEVNLADLVKKIVKKNSLQFKKMDINLISKFESAIVIADEIRLEQAIQNYINNALNHVDKKNIIKITVL
SSGIIKVFNSGKNIEDKYIEKIWHGFVRIDKVRNYKEKRVGLGLTIVREIVKLHKGQYGIENKDLGVEFWIKIPLI

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=343, Percent_Identity=24.198250728863, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI87081816, Length=344, Percent_Identity=24.7093023255814, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1786783, Length=273, Percent_Identity=25.2747252747253, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1786600, Length=284, Percent_Identity=25, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788393, Length=292, Percent_Identity=22.2602739726027, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790861, Length=235, Percent_Identity=28.5106382978723, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI145693157, Length=238, Percent_Identity=23.5294117647059, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790346, Length=213, Percent_Identity=28.6384976525822, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082128, Length=312, Percent_Identity=22.4358974358974, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786912, Length=233, Percent_Identity=24.0343347639485, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788713, Length=236, Percent_Identity=24.1525423728814, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1790436, Length=236, Percent_Identity=26.271186440678, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790551, Length=316, Percent_Identity=22.1518987341772, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788549, Length=314, Percent_Identity=22.6114649681529, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 54807; Mature: 54807

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSIKLKLFFGITLILSIFIVGIIIYGSIFKSYFEKEKLKEMEIIILQIESIIDINHNSD
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHCCCCCCC
FKERVDELADEYNVQIDIKDKNLDKTIYATHEGKNNGGFGQNKFKNIKDIGRINEIDRLI
HHHHHHHHHHHCEEEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCEEE
LYDKSTGVNFLTAIKELDNNLNKIIIKTPINIIDDAKSKSINLLILIFSPIIFLIIVLTL
EEECCCCHHHHHHHHHHCCCCCEEEEECCCHHHCCCCCCCCEEEHHHHHHHHHHHHHHHH
IFSTRFTKPIIEITKKTMKIKELDFSEDIEVKGKDEISVLSKSVNNLSHKIENTLSELNH
HHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
KNLKLESMIKKEKENQKLRKEFVSSVSHELKSPITVILGYAQALSSEIVSSNEDKEYYLG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEEE
VINDEAERMQIIVNDLLDLYKLESNTFSLEIKEVNLADLVKKIVKKNSLQFKKMDINLIS
EECCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHCCCCEEEEHHHHHHH
KFESAIVIADEIRLEQAIQNYINNALNHVDKKNIIKITVLSSGIIKVFNSGKNIEDKYIE
HHHHHEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHCCCCCCHHHHHH
KIWHGFVRIDKVRNYKEKRVGLGLTIVREIVKLHKGQYGIENKDLGVEFWIKIPLI
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCC
>Mature Secondary Structure
MKSIKLKLFFGITLILSIFIVGIIIYGSIFKSYFEKEKLKEMEIIILQIESIIDINHNSD
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHCCCCCCC
FKERVDELADEYNVQIDIKDKNLDKTIYATHEGKNNGGFGQNKFKNIKDIGRINEIDRLI
HHHHHHHHHHHCEEEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCEEE
LYDKSTGVNFLTAIKELDNNLNKIIIKTPINIIDDAKSKSINLLILIFSPIIFLIIVLTL
EEECCCCHHHHHHHHHHCCCCCEEEEECCCHHHCCCCCCCCEEEHHHHHHHHHHHHHHHH
IFSTRFTKPIIEITKKTMKIKELDFSEDIEVKGKDEISVLSKSVNNLSHKIENTLSELNH
HHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
KNLKLESMIKKEKENQKLRKEFVSSVSHELKSPITVILGYAQALSSEIVSSNEDKEYYLG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEEE
VINDEAERMQIIVNDLLDLYKLESNTFSLEIKEVNLADLVKKIVKKNSLQFKKMDINLIS
EECCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHCCCCEEEEHHHHHHH
KFESAIVIADEIRLEQAIQNYINNALNHVDKKNIIKITVLSSGIIKVFNSGKNIEDKYIE
HHHHHEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHCCCCCCHHHHHH
KIWHGFVRIDKVRNYKEKRVGLGLTIVREIVKLHKGQYGIENKDLGVEFWIKIPLI
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]