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The map label for this gene is hypE [H]

Identifier: 187933842

GI number: 187933842

Start: 2082483

End: 2083496

Strand: Reverse

Name: hypE [H]

Synonym: CLL_A2002

Alternate gene names: 187933842

Gene position: 2083496-2082483 (Counterclockwise)

Preceding gene: 187935094

Following gene: 187933101

Centisome position: 54.82

GC content: 29.59

Gene sequence:

>1014_bases
ATGAATAATAAAATAATAACTTTATCACATGGTAGTGGTGGAATAGAAACTTATAAGCTCATAGATGAAATGTTTTATAG
GAACTTTAATAATGATGAATTATTGCAACAAGGCGATTCAACTGTTTTAAATGAAATAAAAGGAAAAATAGCTACTACAA
TAGATGGATTTGTTGTGGATCCAATATTCTTTAAAGGTGGTGATATAGGAAAGTTAAGTTTATGTGGAACTATAAATGAT
TTAGCTGTCAGTGGGGCATGTCCATTATATATTACATGCTCTTTTATTATAGAAGAAGGATTTGAATTCAAAAGTTTAGA
AAAGATAGTACAATCTATGGCAAAGACAGCCAAAGAGTCTAATGTGAAGATTGTTGCAGGAGATACAAAGGTAGTGGAAA
AGGGAAAGGGGCATAAAGTGTATATTAGTACCTGTGGAATAGGATACTTTAAGGAACAGAAGAACATTTTAAATGTAAAT
AATATAAAAAGTGGAGATAAGATAATTTTAAGTGGAACCATTGGTGAGCATGGTATGTGTATAGTGAATAAAAGAGAAAA
TTTAAACATAGATAGTGAAATAAAAAGTGATTGCGCACCATTAAATTCATTATGTGAAATTATATTAAATACAAGTAATA
ATGTAAGAATTATGAGAGATCCAACTAGAGGTGGAATTGCAAATACATTAAATGAATTAAGCAGATCTTCTTTAAAAAGT
ATGATGATTTATGAAGAGTTTATTCCAATAAATAATGATGTAAGGTCGTTTTTTGAATTATTAGGAATGAGTCCATTATA
TATAGCAAATGAAGGAAAGCTTTTGTGCATTGTAGATGAAGTTGATGCTGAAAATGTATTAAGTGCTATGAAAAATCATC
CTTTAGGAAAAGATGCAGCTATTATAGGGGAAGTAATTGAAGAAAACAAAGGGGCAGTATATATAAAAGGATTACTTGGA
TCAACTAAGGTTTTGCAGATGTCACAAGGAGAACTTTTACCACGAATATGTTAA

Upstream 100 bases:

>100_bases
CAATATGCCAAATAGTATTGTAATTGATTTTTAGAATGCTTAAGTGCAGCTTTGTTTATAAATATATTAGTGATCTATTT
TGATTATAGGAGATATTTAG

Downstream 100 bases:

>100_bases
AAATTTATATACCAAGAATTGGAGTTTAAGTGAAATTTAAAAATCCATTAGATGTTAATAATATTTTAAATATATTTACT
TAGCTGGATATATTAAGACA

Product: hydrogenase expression/formation protein HypE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MNNKIITLSHGSGGIETYKLIDEMFYRNFNNDELLQQGDSTVLNEIKGKIATTIDGFVVDPIFFKGGDIGKLSLCGTIND
LAVSGACPLYITCSFIIEEGFEFKSLEKIVQSMAKTAKESNVKIVAGDTKVVEKGKGHKVYISTCGIGYFKEQKNILNVN
NIKSGDKIILSGTIGEHGMCIVNKRENLNIDSEIKSDCAPLNSLCEIILNTSNNVRIMRDPTRGGIANTLNELSRSSLKS
MMIYEEFIPINNDVRSFFELLGMSPLYIANEGKLLCIVDEVDAENVLSAMKNHPLGKDAAIIGEVIEENKGAVYIKGLLG
STKVLQMSQGELLPRIC

Sequences:

>Translated_337_residues
MNNKIITLSHGSGGIETYKLIDEMFYRNFNNDELLQQGDSTVLNEIKGKIATTIDGFVVDPIFFKGGDIGKLSLCGTIND
LAVSGACPLYITCSFIIEEGFEFKSLEKIVQSMAKTAKESNVKIVAGDTKVVEKGKGHKVYISTCGIGYFKEQKNILNVN
NIKSGDKIILSGTIGEHGMCIVNKRENLNIDSEIKSDCAPLNSLCEIILNTSNNVRIMRDPTRGGIANTLNELSRSSLKS
MMIYEEFIPINNDVRSFFELLGMSPLYIANEGKLLCIVDEVDAENVLSAMKNHPLGKDAAIIGEVIEENKGAVYIKGLLG
STKVLQMSQGELLPRIC
>Mature_337_residues
MNNKIITLSHGSGGIETYKLIDEMFYRNFNNDELLQQGDSTVLNEIKGKIATTIDGFVVDPIFFKGGDIGKLSLCGTIND
LAVSGACPLYITCSFIIEEGFEFKSLEKIVQSMAKTAKESNVKIVAGDTKVVEKGKGHKVYISTCGIGYFKEQKNILNVN
NIKSGDKIILSGTIGEHGMCIVNKRENLNIDSEIKSDCAPLNSLCEIILNTSNNVRIMRDPTRGGIANTLNELSRSSLKS
MMIYEEFIPINNDVRSFFELLGMSPLYIANEGKLLCIVDEVDAENVLSAMKNHPLGKDAAIIGEVIEENKGAVYIKGLLG
STKVLQMSQGELLPRIC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=342, Percent_Identity=42.3976608187134, Blast_Score=282, Evalue=2e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 36903; Mature: 36903

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNKIITLSHGSGGIETYKLIDEMFYRNFNNDELLQQGDSTVLNEIKGKIATTIDGFVVD
CCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHCCHHHEEECCEEEC
PIFFKGGDIGKLSLCGTINDLAVSGACPLYITCSFIIEEGFEFKSLEKIVQSMAKTAKES
CEEECCCCCCEEEEECCHHHHHCCCCCCEEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHC
NVKIVAGDTKVVEKGKGHKVYISTCGIGYFKEQKNILNVNNIKSGDKIILSGTIGEHGMC
CEEEEECCHHEECCCCCCEEEEEECCCCEECCCCCCCCCCCCCCCCEEEEEECCCCCCEE
IVNKRENLNIDSEIKSDCAPLNSLCEIILNTSNNVRIMRDPTRGGIANTLNELSRSSLKS
EEECCCCCCCCHHHHHHHCCHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHH
MMIYEEFIPINNDVRSFFELLGMSPLYIANEGKLLCIVDEVDAENVLSAMKNHPLGKDAA
HHHHHHHCCCCHHHHHHHHHHCCCCEEEECCCCEEEEEECCCHHHHHHHHHCCCCCCHHH
IIGEVIEENKGAVYIKGLLGSTKVLQMSQGELLPRIC
HHHHHHHCCCCEEEEEECCCCCEEEEECCCCCCCCCC
>Mature Secondary Structure
MNNKIITLSHGSGGIETYKLIDEMFYRNFNNDELLQQGDSTVLNEIKGKIATTIDGFVVD
CCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHCCHHHEEECCEEEC
PIFFKGGDIGKLSLCGTINDLAVSGACPLYITCSFIIEEGFEFKSLEKIVQSMAKTAKES
CEEECCCCCCEEEEECCHHHHHCCCCCCEEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHC
NVKIVAGDTKVVEKGKGHKVYISTCGIGYFKEQKNILNVNNIKSGDKIILSGTIGEHGMC
CEEEEECCHHEECCCCCCEEEEEECCCCEECCCCCCCCCCCCCCCCEEEEEECCCCCCEE
IVNKRENLNIDSEIKSDCAPLNSLCEIILNTSNNVRIMRDPTRGGIANTLNELSRSSLKS
EEECCCCCCCCHHHHHHHCCHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHH
MMIYEEFIPINNDVRSFFELLGMSPLYIANEGKLLCIVDEVDAENVLSAMKNHPLGKDAA
HHHHHHHCCCCHHHHHHHHHHCCCCEEEECCCCEEEEEECCCHHHHHHHHHCCCCCCHHH
IIGEVIEENKGAVYIKGLLGSTKVLQMSQGELLPRIC
HHHHHHHCCCCEEEEEECCCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8510650; 7906310; 12597275 [H]