Click here to switch to the map view.

The map label for this gene is ywbA [H]

Identifier: 187933792

GI number: 187933792

Start: 2191232

End: 2192482

Strand: Reverse

Name: ywbA [H]

Synonym: CLL_A2095

Alternate gene names: 187933792

Gene position: 2192482-2191232 (Counterclockwise)

Preceding gene: 187935241

Following gene: 187932855

Centisome position: 57.69

GC content: 32.05

Gene sequence:

>1251_bases
ATGAAGAAATTTTTTGATTGGCTGGAAAAATATTTAGTACCACCAATGACAAAATTATCAGAGCAAAGACATCTAAAAGC
TGTAAGGGATGGTATCGTATCAACTATTCCTCTTATAATAGTTGGTAGTTTTTTCTTAGTACTTGCTATTCCACCTAATT
TATATCTTAAAGAAATTGTGCAACCTTACACTAATCAAATAATGTTTCCTTATAGATTGAGCATGGGTATAATGGCACTT
TATGCATCCTTTGGTATAGCACATAGTCTTGCTAAATCTTATAAACTAGATCCATTAACAGGTGCAATTTTAGGACTTGC
AGCATTTTTACTTACAAGTGTACCTGTAAACATTGAAGATCAAGGTTGGATGATATCTTTATCTAATTTAGGTGGATCTG
GAATGTTTGTTGCAATTTTAATGGCTATCTTTGCAGTAGAAATTTTGAGATTTTGTAAAAACAAAAATCTTACAGTTAAA
ATGCCGAAAGAAGTTCCAACATCAGTTGCAAATTCCTTTGCAGCATTAATACCAGCTACATTTATTATTATTCCAATATG
GGTAATTAGGGACTTATTAAACTTTGATATTCAAGGAAATATATTAAAGATATTTATGCCACTTGTAAAAGCAGGAAATT
CTTTACCAGGTATATTAATACCAATATTACTTATAACTTTGTTATGGTCTTGTGGTATACATGGTGATTCAGTTGTTGGT
ACAGTGGCAAGACCAATATGGCTTGCAATGCTTGATAGCAATATTGCAGCACAAGCATCTGGACAACCTGTTCCTAATAT
AGCTCCAGAACCATTTTTCCAATGGTTTGTATGGATTGGAGGTTCAGGAGCAACAATAGGATTAGTTATTTTAATGTTAT
TCTCTAGATCTGTATATTTAAAAGATGTTGGTAAGGCATGTTTAATACCAGGAATATGTAATATTAATGAACCTGTAATC
TTTGGTGTCCCAATAATGTTAAATCCACTATTAATTATACCTTTTGTTGTAGCTCCTTTAGTGTGTGGATGTTTAACTTA
TTTTGCTATGATGCTTAATTTGGTTGCAAGGCCAGTAATTTTACCACCATGGACACTTCCAGCTCCAATAGGGGCATATC
TTGCAACAGGTGGAGATTGGAAAGCTATAGTTTTAATTTTAATAAACATAGCAATTACAGCAGTAATATACTATCCATTC
TTTAGAGCATATGAAGAAAAATTAATGAAAGAAGCATTAGAAGAGAATTAA

Upstream 100 bases:

>100_bases
CTCCTTTAGGAGGAGGAAAAGTTTTAAAGCAAATAAAAGCGTATGCTAAATAGATAATAAAAAACATTTTAATATTTATT
TAAAATAGGAGGAAAGATAA

Downstream 100 bases:

>100_bases
TAGAAATTTAATAGAAAATCTATTAGACTAATTAAAAAAATACAGTTTTGATATATTGAAATCAAAACTGTATTTAAATA
TATTAAAGGAGTTTTATTTA

Product: PTS system, lactose/cellobiose family IIC component

Products: pyruvate; diacetylchitobiose-6-phosphate [Cytoplasm]; cellobiose-6-phosphate [Cytoplasm] [C]

Alternate protein names: Putative PTS system EIIC component [H]

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MKKFFDWLEKYLVPPMTKLSEQRHLKAVRDGIVSTIPLIIVGSFFLVLAIPPNLYLKEIVQPYTNQIMFPYRLSMGIMAL
YASFGIAHSLAKSYKLDPLTGAILGLAAFLLTSVPVNIEDQGWMISLSNLGGSGMFVAILMAIFAVEILRFCKNKNLTVK
MPKEVPTSVANSFAALIPATFIIIPIWVIRDLLNFDIQGNILKIFMPLVKAGNSLPGILIPILLITLLWSCGIHGDSVVG
TVARPIWLAMLDSNIAAQASGQPVPNIAPEPFFQWFVWIGGSGATIGLVILMLFSRSVYLKDVGKACLIPGICNINEPVI
FGVPIMLNPLLIIPFVVAPLVCGCLTYFAMMLNLVARPVILPPWTLPAPIGAYLATGGDWKAIVLILINIAITAVIYYPF
FRAYEEKLMKEALEEN

Sequences:

>Translated_416_residues
MKKFFDWLEKYLVPPMTKLSEQRHLKAVRDGIVSTIPLIIVGSFFLVLAIPPNLYLKEIVQPYTNQIMFPYRLSMGIMAL
YASFGIAHSLAKSYKLDPLTGAILGLAAFLLTSVPVNIEDQGWMISLSNLGGSGMFVAILMAIFAVEILRFCKNKNLTVK
MPKEVPTSVANSFAALIPATFIIIPIWVIRDLLNFDIQGNILKIFMPLVKAGNSLPGILIPILLITLLWSCGIHGDSVVG
TVARPIWLAMLDSNIAAQASGQPVPNIAPEPFFQWFVWIGGSGATIGLVILMLFSRSVYLKDVGKACLIPGICNINEPVI
FGVPIMLNPLLIIPFVVAPLVCGCLTYFAMMLNLVARPVILPPWTLPAPIGAYLATGGDWKAIVLILINIAITAVIYYPF
FRAYEEKLMKEALEEN
>Mature_416_residues
MKKFFDWLEKYLVPPMTKLSEQRHLKAVRDGIVSTIPLIIVGSFFLVLAIPPNLYLKEIVQPYTNQIMFPYRLSMGIMAL
YASFGIAHSLAKSYKLDPLTGAILGLAAFLLTSVPVNIEDQGWMISLSNLGGSGMFVAILMAIFAVEILRFCKNKNLTVK
MPKEVPTSVANSFAALIPATFIIIPIWVIRDLLNFDIQGNILKIFMPLVKAGNSLPGILIPILLITLLWSCGIHGDSVVG
TVARPIWLAMLDSNIAAQASGQPVPNIAPEPFFQWFVWIGGSGATIGLVILMLFSRSVYLKDVGKACLIPGICNINEPVI
FGVPIMLNPLLIIPFVVAPLVCGCLTYFAMMLNLVARPVILPPWTLPAPIGAYLATGGDWKAIVLILINIAITAVIYYPF
FRAYEEKLMKEALEEN

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane [H]

COG id: COG1455

COG function: function code G; Phosphotransferase system cellobiose-specific component IIC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=442, Percent_Identity=30.0904977375566, Blast_Score=180, Evalue=1e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: NA

Molecular weight: Translated: 45677; Mature: 45677

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKFFDWLEKYLVPPMTKLSEQRHLKAVRDGIVSTIPLIIVGSFFLVLAIPPNLYLKEIV
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
QPYTNQIMFPYRLSMGIMALYASFGIAHSLAKSYKLDPLTGAILGLAAFLLTSVPVNIED
HHHHCCEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCC
QGWMISLSNLGGSGMFVAILMAIFAVEILRFCKNKNLTVKMPKEVPTSVANSFAALIPAT
CCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHH
FIIIPIWVIRDLLNFDIQGNILKIFMPLVKAGNSLPGILIPILLITLLWSCGIHGDSVVG
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHH
TVARPIWLAMLDSNIAAQASGQPVPNIAPEPFFQWFVWIGGSGATIGLVILMLFSRSVYL
HHHHHHHHHHHCCCHHCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCHHH
KDVGKACLIPGICNINEPVIFGVPIMLNPLLIIPFVVAPLVCGCLTYFAMMLNLVARPVI
HHCCCHHHCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LPPWTLPAPIGAYLATGGDWKAIVLILINIAITAVIYYPFFRAYEEKLMKEALEEN
CCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKFFDWLEKYLVPPMTKLSEQRHLKAVRDGIVSTIPLIIVGSFFLVLAIPPNLYLKEIV
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
QPYTNQIMFPYRLSMGIMALYASFGIAHSLAKSYKLDPLTGAILGLAAFLLTSVPVNIED
HHHHCCEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCC
QGWMISLSNLGGSGMFVAILMAIFAVEILRFCKNKNLTVKMPKEVPTSVANSFAALIPAT
CCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHH
FIIIPIWVIRDLLNFDIQGNILKIFMPLVKAGNSLPGILIPILLITLLWSCGIHGDSVVG
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHH
TVARPIWLAMLDSNIAAQASGQPVPNIAPEPFFQWFVWIGGSGATIGLVILMLFSRSVYL
HHHHHHHHHHHCCCHHCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCHHH
KDVGKACLIPGICNINEPVIFGVPIMLNPLLIIPFVVAPLVCGCLTYFAMMLNLVARPVI
HHCCCHHHCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LPPWTLPAPIGAYLATGGDWKAIVLILINIAITAVIYYPFFRAYEEKLMKEALEEN
CCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: diacetylchitobiose [Periplasm]; phosphoenolpyruvate; cellobiose [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + diacetylchitobiose [Periplasm] = pyruvate + diacetylchitobiose-6-phosphate [Cytoplasm] phosphoenolpyruvate + cellobiose [Periplasm] = cellobiose-6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]