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The map label for this gene is licH [H]

Identifier: 187932855

GI number: 187932855

Start: 2189819

End: 2191132

Strand: Reverse

Name: licH [H]

Synonym: CLL_A2094

Alternate gene names: 187932855

Gene position: 2191132-2189819 (Counterclockwise)

Preceding gene: 187933792

Following gene: 187935639

Centisome position: 57.66

GC content: 28.54

Gene sequence:

>1314_bases
ATGAAAAAATTAAAAATAGCAATAATAGGTGGAGGAAGTAGTTATACACCAGAAATAATAGAAGGATTTATAAAGAGAGA
AGGAGAACTTCCAGTAAAAGAAATTTATTTAGTAGATATAAAAGATGGAGAAGAAAAACTTAATATTGTAGGTAACTTAG
CTAAAAGAATGATAAAAAAAGTAGGATTAGATATTAAGATTATTCTTACATTAGATAGAAGAGAAGCTTTAAAAGATGCA
GATTTTGTAACAACTCAATTTAGAATTGGAGGATTAGATGCCAGAGTAAGGGATGAAAGATTTCCCCTTAAATATGATGT
ATTAGGACAAGAAACAGTAGGGCCAGGAGGTCTTGCAAAAGCATTAAGAACAATTCCAGTGATTTTAGATATATGCAAGG
ACATGAAAGAGCTTTGCCCAAATGCATATCTTATTAATTTTACAAATCCATCAGGAATGGTTACAGAAGCAGTAAACAAA
TATACTAATATAAAATGTATAGGATTATGTAATGTACCTATACATATGAAAATGGACATAGCAAAAATGTTAGATGTAGA
TACTAAAGATTTATTTATAGAATTTGTGGGACTTAATCATCTGGTTTGGGGAAGAAAAGTATGGTATAAGGGTGAAGATA
TAACTAAAAAAGTTATAGAAGGCTTAAAAGATGGTGCATCATTGACTATGAAGAATATATCTGATTTAAAATGGCCAGTA
GAATTTTTAGATGCTTTAAAAATGATACCATGTCCATATCACAGATATTATTATATGACAGATAGGCTTTTGGATGAAGA
AAAAAAATCAGCACAAGATGGACAATTAGGAACAAGAGCTGAACAAGTTAAAAGAGTTGAAAAAAAATTATTTGAGTTAT
ATAAAAGTGAAAACTTAGATGTAAAACCAACTCAACTTGAAAAACGGGGTGGTGCATATTATTCTGATGCGGCAGTTTCC
CTTATTAGTGCTATTTATAATGATAAAAAAGAAATCCATACAGTTAATATTAAAAATAATGGAATAATAAAAGGAATTCC
TAATGATGCAATAATTGAAACTAATTGCTTAATAGATAAAAGAGGTGCAACACCATTAGCATTAACAGGAGATTTAGAAA
TTAAAATATTAGGACTTATTCAAAGTGTTAAGGCTTATGAAACTTTAGCTGTTGAATCTGCAATTACTGGTGATAAGAAT
ACAGCAATCATGGCCCTTACCAATAATCCATTAATTTCATCTATTGATAAGTCAATAAAATTAGTTAATGAATTAATAGA
AATAAATAAATGTTATTTACCACAGTTTAAATAA

Upstream 100 bases:

>100_bases
ATAGAAATTTAATAGAAAATCTATTAGACTAATTAAAAAAATACAGTTTTGATATATTGAAATCAAAACTGTATTTAAAT
ATATTAAAGGAGTTTTATTT

Downstream 100 bases:

>100_bases
AAAATAACCAAGGAGGAATTTTAAATGGAAGAAAAAATATTTGAAATAATATCACACAGTGGAGATTCAAGAGGATACAC
TTTTCAAGCTTTAAAAGAGG

Product: 6-phospho-beta-glucosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MKKLKIAIIGGGSSYTPEIIEGFIKREGELPVKEIYLVDIKDGEEKLNIVGNLAKRMIKKVGLDIKIILTLDRREALKDA
DFVTTQFRIGGLDARVRDERFPLKYDVLGQETVGPGGLAKALRTIPVILDICKDMKELCPNAYLINFTNPSGMVTEAVNK
YTNIKCIGLCNVPIHMKMDIAKMLDVDTKDLFIEFVGLNHLVWGRKVWYKGEDITKKVIEGLKDGASLTMKNISDLKWPV
EFLDALKMIPCPYHRYYYMTDRLLDEEKKSAQDGQLGTRAEQVKRVEKKLFELYKSENLDVKPTQLEKRGGAYYSDAAVS
LISAIYNDKKEIHTVNIKNNGIIKGIPNDAIIETNCLIDKRGATPLALTGDLEIKILGLIQSVKAYETLAVESAITGDKN
TAIMALTNNPLISSIDKSIKLVNELIEINKCYLPQFK

Sequences:

>Translated_437_residues
MKKLKIAIIGGGSSYTPEIIEGFIKREGELPVKEIYLVDIKDGEEKLNIVGNLAKRMIKKVGLDIKIILTLDRREALKDA
DFVTTQFRIGGLDARVRDERFPLKYDVLGQETVGPGGLAKALRTIPVILDICKDMKELCPNAYLINFTNPSGMVTEAVNK
YTNIKCIGLCNVPIHMKMDIAKMLDVDTKDLFIEFVGLNHLVWGRKVWYKGEDITKKVIEGLKDGASLTMKNISDLKWPV
EFLDALKMIPCPYHRYYYMTDRLLDEEKKSAQDGQLGTRAEQVKRVEKKLFELYKSENLDVKPTQLEKRGGAYYSDAAVS
LISAIYNDKKEIHTVNIKNNGIIKGIPNDAIIETNCLIDKRGATPLALTGDLEIKILGLIQSVKAYETLAVESAITGDKN
TAIMALTNNPLISSIDKSIKLVNELIEINKCYLPQFK
>Mature_437_residues
MKKLKIAIIGGGSSYTPEIIEGFIKREGELPVKEIYLVDIKDGEEKLNIVGNLAKRMIKKVGLDIKIILTLDRREALKDA
DFVTTQFRIGGLDARVRDERFPLKYDVLGQETVGPGGLAKALRTIPVILDICKDMKELCPNAYLINFTNPSGMVTEAVNK
YTNIKCIGLCNVPIHMKMDIAKMLDVDTKDLFIEFVGLNHLVWGRKVWYKGEDITKKVIEGLKDGASLTMKNISDLKWPV
EFLDALKMIPCPYHRYYYMTDRLLDEEKKSAQDGQLGTRAEQVKRVEKKLFELYKSENLDVKPTQLEKRGGAYYSDAAVS
LISAIYNDKKEIHTVNIKNNGIIKGIPNDAIIETNCLIDKRGATPLALTGDLEIKILGLIQSVKAYETLAVESAITGDKN
TAIMALTNNPLISSIDKSIKLVNELIEINKCYLPQFK

Specific function: Hydrolyzes phospho-beta-glucosides (Probable) [H]

COG id: COG1486

COG function: function code G; Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 4 family [H]

Homologues:

Organism=Escherichia coli, GI1788029, Length=439, Percent_Identity=49.2027334851936, Blast_Score=414, Evalue=1e-117,
Organism=Escherichia coli, GI1790560, Length=461, Percent_Identity=27.5488069414317, Blast_Score=154, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019802
- InterPro:   IPR001088
- InterPro:   IPR022616
- InterPro:   IPR015955
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02056 Glyco_hydro_4; PF11975 Glyco_hydro_4C [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 49031; Mature: 49031

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: PS01324 GLYCOSYL_HYDROL_F4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLKIAIIGGGSSYTPEIIEGFIKREGELPVKEIYLVDIKDGEEKLNIVGNLAKRMIKK
CCEEEEEEEECCCCCCHHHHHHHHHCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHH
VGLDIKIILTLDRREALKDADFVTTQFRIGGLDARVRDERFPLKYDVLGQETVGPGGLAK
HCCCEEEEEEECHHHHHCCCCEEEEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCHHHH
ALRTIPVILDICKDMKELCPNAYLINFTNPSGMVTEAVNKYTNIKCIGLCNVPIHMKMDI
HHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCEEEEEEECCCEEEEECH
AKMLDVDTKDLFIEFVGLNHLVWGRKVWYKGEDITKKVIEGLKDGASLTMKNISDLKWPV
HHHHCCCCHHHEEEEECCCCEEECCEEEECCCHHHHHHHHHHCCCCCEEECCHHHCCCHH
EFLDALKMIPCPYHRYYYMTDRLLDEEKKSAQDGQLGTRAEQVKRVEKKLFELYKSENLD
HHHHHHHHCCCCCHHEEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
VKPTQLEKRGGAYYSDAAVSLISAIYNDKKEIHTVNIKNNGIIKGIPNDAIIETNCLIDK
CCCHHHHHCCCCEEHHHHHHHHHHHHCCCCCEEEEEECCCCEEEECCCCCEEEEEEEEEC
RGATPLALTGDLEIKILGLIQSVKAYETLAVESAITGDKNTAIMALTNNPLISSIDKSIK
CCCCCEEEECCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHH
LVNELIEINKCYLPQFK
HHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKKLKIAIIGGGSSYTPEIIEGFIKREGELPVKEIYLVDIKDGEEKLNIVGNLAKRMIKK
CCEEEEEEEECCCCCCHHHHHHHHHCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHH
VGLDIKIILTLDRREALKDADFVTTQFRIGGLDARVRDERFPLKYDVLGQETVGPGGLAK
HCCCEEEEEEECHHHHHCCCCEEEEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCHHHH
ALRTIPVILDICKDMKELCPNAYLINFTNPSGMVTEAVNKYTNIKCIGLCNVPIHMKMDI
HHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCEEEEEEECCCEEEEECH
AKMLDVDTKDLFIEFVGLNHLVWGRKVWYKGEDITKKVIEGLKDGASLTMKNISDLKWPV
HHHHCCCCHHHEEEEECCCCEEECCEEEECCCHHHHHHHHHHCCCCCEEECCHHHCCCHH
EFLDALKMIPCPYHRYYYMTDRLLDEEKKSAQDGQLGTRAEQVKRVEKKLFELYKSENLD
HHHHHHHHCCCCCHHEEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
VKPTQLEKRGGAYYSDAAVSLISAIYNDKKEIHTVNIKNNGIIKGIPNDAIIETNCLIDK
CCCHHHHHCCCCEEHHHHHHHHHHHHCCCCCEEEEEECCCCEEEECCCCCEEEEEEEEEC
RGATPLALTGDLEIKILGLIQSVKAYETLAVESAITGDKNTAIMALTNNPLISSIDKSIK
CCCCCEEEECCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHH
LVNELIEINKCYLPQFK
HHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8990303; 9384377; 8969509 [H]