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The map label for this gene is clpX [H]

Identifier: 187933551

GI number: 187933551

Start: 2968198

End: 2969487

Strand: Reverse

Name: clpX [H]

Synonym: CLL_A2888

Alternate gene names: 187933551

Gene position: 2969487-2968198 (Counterclockwise)

Preceding gene: 187935559

Following gene: 187933930

Centisome position: 78.14

GC content: 31.01

Gene sequence:

>1290_bases
ATGGCTAAATATGATGAAAAGAAACAGTTGAAATGTTCATTTTGTGGTAAAACTCAAGACCAAGTAAAAAGGTTAATAGC
AGGTCCAGGAGTATATATTTGTGATGAATGTATAGATTTATGTTCAGAAATAATAGCAGATGAATTTGAAGAAACTGTGG
AATTCGATACAAAAAGTGTACCTAAACCCAATGAAATAAAACAATATTTAGATTCTTATGTAATTGGTCAAGAAAGAGCT
AAAAAATCATTATCAGTAGCTGTTTACAATCATTACAAAAGAATTAATACTAATAAGCAAGATACGGATGTAGAATTATC
AAAGAGTAACATTCTATTGTTAGGACCAACAGGTTCTGGTAAAACGTTACTTGCTCAGACACTTGCGAAAGTTTTAAACG
TTCCATTTGCAATAGCAGATGCCACAACATTAACAGAAGCAGGATATGTTGGAGAAGATGTTGAAAATATTCTTCTTAAA
TTAATACAAAATGCTGATTATGATGTTGAGAGAGCCGAAAGAGGAATTATCTATATAGATGAAATAGATAAAATTGCAAG
AAAATCTGAAAATCCTTCAATAACTAGAGATGTATCTGGTGAAGGCGTTCAACAAGCATTATTAAAGATATTAGAAGGAA
CAGTTGCTTCAGTACCACCTCAAGGTGGCAGAAAGCATCCACATCAAGAGTTTATTCAAATAAATACATCTAATATATTA
TTTATTTGTGGTGGTGCATTTGATGGTGTTGATAAAATAATAGAAAATAGAACTAGAAAAAGTTCTATGGGATTTGGTGC
TCAAATTCAAGGTAAGCATGAAAAAGATATTGGTAAACTTCTAAAAGAAATAATGCCAGGAGATTTACTTAAGTTTGGAT
TAATCCCTGAATTTGTTGGAAGACTTCCAATACTAGTAACTTTAGAGTCATTAGATAAAGATGCTTTAATAAACATCTTA
ACTAAACCAAAAAATGCTCTTGTAAAACAATACAAGAAGCTGTTTGAATTAGATGATGTTGAACTTGAGTTTAACAATGA
AGCACTGACATCTATTGCAGAAGAAGCTATAGAGAGAAAGACTGGTGCAAGAGGATTAAGAGCCATCATAGAAGAAATGA
TGACAGAAATAATGTATGAAATACCTTCAGATGAACAGATAACAAAAGTTACTATAACTGAAGAATGCATTAAGGATAAA
GAAAATCCTCAAGTAGAAAGATTACCGGAAGGTAAAACAAGAGGAACTTTAGCATCAAATAGAGTTAAAAAAGATATTGA
ATCAGCTTAA

Upstream 100 bases:

>100_bases
TAAGACATATGGGTTAGTAGATAAAGTAATAACTAAGAATGAAACTGGAAAAGATAAATAAGATTGCAATTTAATTTATT
GTACTAAGTGAGGTGAATAT

Downstream 100 bases:

>100_bases
TCTTAATACTGATATCTAAATAGATATCAGTATTTTTGTTCTTATATAGATATTTGAAAATGAACTGATATTAATGGAAT
AAAAAATATATATCTATTTA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MAKYDEKKQLKCSFCGKTQDQVKRLIAGPGVYICDECIDLCSEIIADEFEETVEFDTKSVPKPNEIKQYLDSYVIGQERA
KKSLSVAVYNHYKRINTNKQDTDVELSKSNILLLGPTGSGKTLLAQTLAKVLNVPFAIADATTLTEAGYVGEDVENILLK
LIQNADYDVERAERGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQINTSNIL
FICGGAFDGVDKIIENRTRKSSMGFGAQIQGKHEKDIGKLLKEIMPGDLLKFGLIPEFVGRLPILVTLESLDKDALINIL
TKPKNALVKQYKKLFELDDVELEFNNEALTSIAEEAIERKTGARGLRAIIEEMMTEIMYEIPSDEQITKVTITEECIKDK
ENPQVERLPEGKTRGTLASNRVKKDIESA

Sequences:

>Translated_429_residues
MAKYDEKKQLKCSFCGKTQDQVKRLIAGPGVYICDECIDLCSEIIADEFEETVEFDTKSVPKPNEIKQYLDSYVIGQERA
KKSLSVAVYNHYKRINTNKQDTDVELSKSNILLLGPTGSGKTLLAQTLAKVLNVPFAIADATTLTEAGYVGEDVENILLK
LIQNADYDVERAERGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQINTSNIL
FICGGAFDGVDKIIENRTRKSSMGFGAQIQGKHEKDIGKLLKEIMPGDLLKFGLIPEFVGRLPILVTLESLDKDALINIL
TKPKNALVKQYKKLFELDDVELEFNNEALTSIAEEAIERKTGARGLRAIIEEMMTEIMYEIPSDEQITKVTITEECIKDK
ENPQVERLPEGKTRGTLASNRVKKDIESA
>Mature_428_residues
AKYDEKKQLKCSFCGKTQDQVKRLIAGPGVYICDECIDLCSEIIADEFEETVEFDTKSVPKPNEIKQYLDSYVIGQERAK
KSLSVAVYNHYKRINTNKQDTDVELSKSNILLLGPTGSGKTLLAQTLAKVLNVPFAIADATTLTEAGYVGEDVENILLKL
IQNADYDVERAERGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQINTSNILF
ICGGAFDGVDKIIENRTRKSSMGFGAQIQGKHEKDIGKLLKEIMPGDLLKFGLIPEFVGRLPILVTLESLDKDALINILT
KPKNALVKQYKKLFELDDVELEFNNEALTSIAEEAIERKTGARGLRAIIEEMMTEIMYEIPSDEQITKVTITEECIKDKE
NPQVERLPEGKTRGTLASNRVKKDIESA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=333, Percent_Identity=49.8498498498498, Blast_Score=316, Evalue=3e-86,
Organism=Escherichia coli, GI1786642, Length=399, Percent_Identity=63.4085213032581, Blast_Score=530, Evalue=1e-152,
Organism=Escherichia coli, GI1790366, Length=103, Percent_Identity=43.6893203883495, Blast_Score=94, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71982908, Length=312, Percent_Identity=46.1538461538462, Blast_Score=278, Evalue=6e-75,
Organism=Caenorhabditis elegans, GI71982905, Length=312, Percent_Identity=46.1538461538462, Blast_Score=277, Evalue=9e-75,
Organism=Caenorhabditis elegans, GI71988663, Length=412, Percent_Identity=39.5631067961165, Blast_Score=267, Evalue=7e-72,
Organism=Caenorhabditis elegans, GI71988660, Length=255, Percent_Identity=40.3921568627451, Blast_Score=174, Evalue=9e-44,
Organism=Saccharomyces cerevisiae, GI6319704, Length=425, Percent_Identity=39.2941176470588, Blast_Score=275, Evalue=1e-74,
Organism=Drosophila melanogaster, GI24648291, Length=338, Percent_Identity=47.0414201183432, Blast_Score=313, Evalue=1e-85,
Organism=Drosophila melanogaster, GI24648289, Length=338, Percent_Identity=47.0414201183432, Blast_Score=313, Evalue=1e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 47808; Mature: 47677

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKYDEKKQLKCSFCGKTQDQVKRLIAGPGVYICDECIDLCSEIIADEFEETVEFDTKSV
CCCCCCCCCCCHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PKPNEIKQYLDSYVIGQERAKKSLSVAVYNHYKRINTNKQDTDVELSKSNILLLGPTGSG
CCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCEEEECCCCCC
KTLLAQTLAKVLNVPFAIADATTLTEAGYVGEDVENILLKLIQNADYDVERAERGIIYID
HHHHHHHHHHHHCCCEEEECHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHCCCEEEEH
EIDKIARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQINTSNIL
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCHHHHEEECCCCEE
FICGGAFDGVDKIIENRTRKSSMGFGAQIQGKHEKDIGKLLKEIMPGDLLKFGLIPEFVG
EEECCCHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHCCCHHHHHHCCHHHHC
RLPILVTLESLDKDALINILTKPKNALVKQYKKLFELDDVELEFNNEALTSIAEEAIERK
CCCEEEEHHHCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHH
TGARGLRAIIEEMMTEIMYEIPSDEQITKVTITEECIKDKENPQVERLPEGKTRGTLASN
HCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHCCCCCCCHHCCCCCCCCCCHHHH
RVKKDIESA
HHHHHHCCC
>Mature Secondary Structure 
AKYDEKKQLKCSFCGKTQDQVKRLIAGPGVYICDECIDLCSEIIADEFEETVEFDTKSV
CCCCCCCCCCHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PKPNEIKQYLDSYVIGQERAKKSLSVAVYNHYKRINTNKQDTDVELSKSNILLLGPTGSG
CCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCEEEECCCCCC
KTLLAQTLAKVLNVPFAIADATTLTEAGYVGEDVENILLKLIQNADYDVERAERGIIYID
HHHHHHHHHHHHCCCEEEECHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHCCCEEEEH
EIDKIARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQINTSNIL
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCHHHHEEECCCCEE
FICGGAFDGVDKIIENRTRKSSMGFGAQIQGKHEKDIGKLLKEIMPGDLLKFGLIPEFVG
EEECCCHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHCCCHHHHHHCCHHHHC
RLPILVTLESLDKDALINILTKPKNALVKQYKKLFELDDVELEFNNEALTSIAEEAIERK
CCCEEEEHHHCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHH
TGARGLRAIIEEMMTEIMYEIPSDEQITKVTITEECIKDKENPQVERLPEGKTRGTLASN
HCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHCCCCCCCHHCCCCCCCCCCHHHH
RVKKDIESA
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA