BacMap

Definition	Clostridium botulinum B str. Eklund 17B, complete genome.
Accession	NC_010674
Length	3,800,327

Click here to switch to the map view.

The map label for this gene is yocR [H]

Identifier: 187933429

GI number: 187933429

Start: 3022429

End: 3023742

Strand: Reverse

Name: yocR [H]

Synonym: CLL_A2941

Alternate gene names: 187933429

Gene position: 3023742-3022429 (Counterclockwise)

Preceding gene: 187934118

Following gene: 187934982

Centisome position: 79.57

GC content: 30.06

Gene sequence:

>1314_bases
GTGAGTAAAAGAGAAGGCTTTTCAAGCAAATTAGGATTTATACTATCTTGTATTGGAGCAGCAATAGGTTTAGGAAATGT
ATGGATGTTTCCTTATAAGTTGGGCGAAAATGGAGGAGCAGCATTTTTAATTCCATATTTTTTATTTGTTATTATTTTAG
GTGTAGTCGGATTAATGGGAGAGTTTGCATTTGGAAGAATGTACAAACAAGGATCATTAGGAGGAATAAGACAAGCTTTT
AAAGAGAAGAATATAAAAGGTGGAAAAATAATATCTATAATTCCGACCCTTGGATTGACAGGCATATTTATGTTTTATAC
AGTTGTAATTGGATGGGTATTAAAGTACTTTTTTATAAGTTTAACTGGAGAAATATCATCAATAAACACTGAATCATATT
TTGCCAATTTTTCTAATAGTCCTAATGTTATATTATGGCATGCACTAGCTGTGGTAATAACACTAGTAATAGTAAGTTTT
GGAGTAACAAAAGGGATTGAAAAGATTAATAAAATAATTATTCCATTGTTATTTATTATTTTTATAGTTTTAATAATCAA
ATCTTTAAGCTTACCTAATTCACTTGCAGGAGTAGAATATTTGTTAAAACCTGATTGGGGACATTTATTAAAACCAAGCA
CATGGGTTATGGCGCTAGGACAAGCATTCTTTACAGTATCTATAACTGGATGTTGTATGGTCGCGTGTGGAAGTTATGCT
GAGGATAAATTTGATATACCCAATTGTGCTATAAATACAGCTGCATTTGATACTTTATCAGCATTGTTAGCTGCATTTAT
GATTATGCCAGCAGTTTTTGCATTAGGATTAAGCCCTACAGCAGGACCTGCATTAATGTTTGTTACAGTACCAAGTATAT
TTCAAACAATGCCATTAGGCAGTTTATTAAGTGCATTATTCTTTTTAAGTATAATATTTGCATCTATTTCTTCATCAATA
GCAATGCTTGAAGGACCTGTAGAGGCAGTTTTAAGTATAACTAATTGGAGTAGAAAAAAAGCAACAATAATTATAGCTAG
TGTAGCATTTATTTTTGCAATTCCATTAGGTCTTAATGGAGAATTATTTAATAATTTTACAAACTTCATAACAATAATAT
TATCACCAATAGGAGCAGTAATAACAGCATTTGTTTTCTACTATATAGTTGATAATAAAAGAGCACTAGATGAAGTAAAT
AAAGGTGCAAAATATAAACTGGGAATTGGATTTATTAAATTTGGTAAATACATATTTGTTCCAGCAACAATAATTATAAT
AATTCTTGGAGTTATATATGGAGGAATCGGTTAA

Upstream 100 bases:

>100_bases
GAAAAATACATATTTTATTTACATAATGTTATTTTTTCCATATAATAGTTAATGTGCGTTAATTTTAATGTTGAAATTTA
ATAATTAGAGGAGGAATATA

Downstream 100 bases:

>100_bases
TTTATATTTTAGTTATATATTAAAGAATATAAATATAAAAAGTTACCTTAATAATATGAAAATTATTTAAAGGTAACTTT
TTTATTTATTATTTTTAAGT

Product: sodium:neurotransmitter symporter family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MSKREGFSSKLGFILSCIGAAIGLGNVWMFPYKLGENGGAAFLIPYFLFVIILGVVGLMGEFAFGRMYKQGSLGGIRQAF
KEKNIKGGKIISIIPTLGLTGIFMFYTVVIGWVLKYFFISLTGEISSINTESYFANFSNSPNVILWHALAVVITLVIVSF
GVTKGIEKINKIIIPLLFIIFIVLIIKSLSLPNSLAGVEYLLKPDWGHLLKPSTWVMALGQAFFTVSITGCCMVACGSYA
EDKFDIPNCAINTAAFDTLSALLAAFMIMPAVFALGLSPTAGPALMFVTVPSIFQTMPLGSLLSALFFLSIIFASISSSI
AMLEGPVEAVLSITNWSRKKATIIIASVAFIFAIPLGLNGELFNNFTNFITIILSPIGAVITAFVFYYIVDNKRALDEVN
KGAKYKLGIGFIKFGKYIFVPATIIIIILGVIYGGIG

Sequences:

>Translated_437_residues
MSKREGFSSKLGFILSCIGAAIGLGNVWMFPYKLGENGGAAFLIPYFLFVIILGVVGLMGEFAFGRMYKQGSLGGIRQAF
KEKNIKGGKIISIIPTLGLTGIFMFYTVVIGWVLKYFFISLTGEISSINTESYFANFSNSPNVILWHALAVVITLVIVSF
GVTKGIEKINKIIIPLLFIIFIVLIIKSLSLPNSLAGVEYLLKPDWGHLLKPSTWVMALGQAFFTVSITGCCMVACGSYA
EDKFDIPNCAINTAAFDTLSALLAAFMIMPAVFALGLSPTAGPALMFVTVPSIFQTMPLGSLLSALFFLSIIFASISSSI
AMLEGPVEAVLSITNWSRKKATIIIASVAFIFAIPLGLNGELFNNFTNFITIILSPIGAVITAFVFYYIVDNKRALDEVN
KGAKYKLGIGFIKFGKYIFVPATIIIIILGVIYGGIG
>Mature_436_residues
SKREGFSSKLGFILSCIGAAIGLGNVWMFPYKLGENGGAAFLIPYFLFVIILGVVGLMGEFAFGRMYKQGSLGGIRQAFK
EKNIKGGKIISIIPTLGLTGIFMFYTVVIGWVLKYFFISLTGEISSINTESYFANFSNSPNVILWHALAVVITLVIVSFG
VTKGIEKINKIIIPLLFIIFIVLIIKSLSLPNSLAGVEYLLKPDWGHLLKPSTWVMALGQAFFTVSITGCCMVACGSYAE
DKFDIPNCAINTAAFDTLSALLAAFMIMPAVFALGLSPTAGPALMFVTVPSIFQTMPLGSLLSALFFLSIIFASISSSIA
MLEGPVEAVLSITNWSRKKATIIIASVAFIFAIPLGLNGELFNNFTNFITIILSPIGAVITAFVFYYIVDNKRALDEVNK
GAKYKLGIGFIKFGKYIFVPATIIIIILGVIYGGIG

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI4507043, Length=406, Percent_Identity=27.8325123152709, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI188528618, Length=396, Percent_Identity=26.7676767676768, Blast_Score=136, Evalue=5e-32,
Organism=Homo sapiens, GI171184408, Length=398, Percent_Identity=27.8894472361809, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI171184406, Length=398, Percent_Identity=27.8894472361809, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI171184404, Length=398, Percent_Identity=27.8894472361809, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI4507041, Length=429, Percent_Identity=24.4755244755245, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI21361581, Length=386, Percent_Identity=25.9067357512953, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI7657587, Length=386, Percent_Identity=27.720207253886, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI134304856, Length=383, Percent_Identity=27.154046997389, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI5032097, Length=501, Percent_Identity=25.3493013972056, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI197276623, Length=419, Percent_Identity=24.3436754176611, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI54607094, Length=419, Percent_Identity=24.3436754176611, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI218563756, Length=496, Percent_Identity=25.8064516129032, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI67782317, Length=462, Percent_Identity=24.6753246753247, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI67782313, Length=462, Percent_Identity=24.6753246753247, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI51468073, Length=509, Percent_Identity=22.9862475442043, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI67782315, Length=462, Percent_Identity=24.6753246753247, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI194018524, Length=308, Percent_Identity=26.2987012987013, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI289191351, Length=387, Percent_Identity=25.0645994832041, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI4557046, Length=387, Percent_Identity=25.0645994832041, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI289191377, Length=387, Percent_Identity=25.0645994832041, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI11181770, Length=301, Percent_Identity=25.9136212624585, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI58219014, Length=296, Percent_Identity=26.3513513513513, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI33354281, Length=309, Percent_Identity=26.537216828479, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI92859670, Length=412, Percent_Identity=24.2718446601942, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI300360519, Length=349, Percent_Identity=23.4957020057307, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI12408638, Length=282, Percent_Identity=25.177304964539, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI21361693, Length=234, Percent_Identity=26.0683760683761, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI6005715, Length=178, Percent_Identity=33.1460674157303, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI197276625, Length=148, Percent_Identity=30.4054054054054, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI218563758, Length=317, Percent_Identity=24.9211356466877, Blast_Score=67, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17555248, Length=388, Percent_Identity=26.0309278350515, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17554804, Length=383, Percent_Identity=27.9373368146214, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71995588, Length=376, Percent_Identity=23.1382978723404, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI25146584, Length=413, Percent_Identity=22.7602905569007, Blast_Score=88, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI71998244, Length=344, Percent_Identity=25.5813953488372, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI133952791, Length=214, Percent_Identity=26.1682242990654, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17569475, Length=515, Percent_Identity=20.9708737864078, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17535731, Length=121, Percent_Identity=32.2314049586777, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24762620, Length=422, Percent_Identity=28.6729857819905, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI17136952, Length=445, Percent_Identity=22.4719101123595, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI281364394, Length=431, Percent_Identity=22.5058004640371, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI28574704, Length=431, Percent_Identity=22.5058004640371, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI17136950, Length=431, Percent_Identity=22.5058004640371, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI28574702, Length=431, Percent_Identity=22.5058004640371, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI45551183, Length=420, Percent_Identity=24.7619047619048, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI45550877, Length=422, Percent_Identity=24.1706161137441, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI281365034, Length=412, Percent_Identity=25.2427184466019, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI19921936, Length=378, Percent_Identity=25.9259259259259, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24661428, Length=374, Percent_Identity=26.4705882352941, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24582567, Length=416, Percent_Identity=25.9615384615385, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI45551088, Length=383, Percent_Identity=25.8485639686684, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24652942, Length=383, Percent_Identity=25.8485639686684, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI19921352, Length=421, Percent_Identity=23.9904988123515, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24584353, Length=421, Percent_Identity=23.9904988123515, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24639514, Length=510, Percent_Identity=23.5294117647059, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI221329674, Length=510, Percent_Identity=23.5294117647059, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI281363702, Length=367, Percent_Identity=23.7057220708447, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24639516, Length=531, Percent_Identity=23.728813559322, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24655079, Length=297, Percent_Identity=27.9461279461279, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI281363700, Length=297, Percent_Identity=23.9057239057239, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24639853, Length=403, Percent_Identity=23.8213399503722, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281364136, Length=405, Percent_Identity=22.2222222222222, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24654186, Length=147, Percent_Identity=30.6122448979592, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24582569, Length=378, Percent_Identity=23.015873015873, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 47177; Mature: 47046

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKREGFSSKLGFILSCIGAAIGLGNVWMFPYKLGENGGAAFLIPYFLFVIILGVVGLMG
CCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHH
EFAFGRMYKQGSLGGIRQAFKEKNIKGGKIISIIPTLGLTGIFMFYTVVIGWVLKYFFIS
HHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTGEISSINTESYFANFSNSPNVILWHALAVVITLVIVSFGVTKGIEKINKIIIPLLFII
HCCCHHCCCCHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIVLIIKSLSLPNSLAGVEYLLKPDWGHLLKPSTWVMALGQAFFTVSITGCCMVACGSYA
HHHHHHHHCCCCCHHHCHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EDKFDIPNCAINTAAFDTLSALLAAFMIMPAVFALGLSPTAGPALMFVTVPSIFQTMPLG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHCCHH
SLLSALFFLSIIFASISSSIAMLEGPVEAVLSITNWSRKKATIIIASVAFIFAIPLGLNG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCH
ELFNNFTNFITIILSPIGAVITAFVFYYIVDNKRALDEVNKGAKYKLGIGFIKFGKYIFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEECHHHHHCCCHHH
PATIIIIILGVIYGGIG
HHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SKREGFSSKLGFILSCIGAAIGLGNVWMFPYKLGENGGAAFLIPYFLFVIILGVVGLMG
CCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHH
EFAFGRMYKQGSLGGIRQAFKEKNIKGGKIISIIPTLGLTGIFMFYTVVIGWVLKYFFIS
HHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTGEISSINTESYFANFSNSPNVILWHALAVVITLVIVSFGVTKGIEKINKIIIPLLFII
HCCCHHCCCCHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIVLIIKSLSLPNSLAGVEYLLKPDWGHLLKPSTWVMALGQAFFTVSITGCCMVACGSYA
HHHHHHHHCCCCCHHHCHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EDKFDIPNCAINTAAFDTLSALLAAFMIMPAVFALGLSPTAGPALMFVTVPSIFQTMPLG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHCCHH
SLLSALFFLSIIFASISSSIAMLEGPVEAVLSITNWSRKKATIIIASVAFIFAIPLGLNG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCH
ELFNNFTNFITIILSPIGAVITAFVFYYIVDNKRALDEVNKGAKYKLGIGFIKFGKYIFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEECHHHHHCCCHHH
PATIIIIILGVIYGGIG
HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]