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The map label for this gene is cbiK [H]

Identifier: 187934982

GI number: 187934982

Start: 3020215

End: 3021051

Strand: Reverse

Name: cbiK [H]

Synonym: CLL_A2939

Alternate gene names: 187934982

Gene position: 3021051-3020215 (Counterclockwise)

Preceding gene: 187933429

Following gene: 187933062

Centisome position: 79.49

GC content: 28.2

Gene sequence:

>837_bases
ATGAAAAAAGCAATTTTAGTAGTTAGTTTTGGGACAAGCCACATAGATGCATTAGAAAATTCTATTGAAAGAATCGAGAA
TAAAATAAGATCTGAATTTAAAGATTATGAAATATTCAGGGCTTTTACAGCACATAAAATAATAAAAAAGTTAAAGAATG
TTCATAATTTAGAAATAGCTACACCAGAAGAAGCATTAGAAGATTTATATAGAAAAGGATTTGAAGAAATTATAGTTCAA
CCATTACATATAATTCCTGGTGAAGAATTTGATTATATAAAAGGTGTAGCAAAAAGATTTGAAGATAGGTTTTCCTCTCT
TAAGCTTGGTAGACCAATATTTTATTATCAAGGAATAGAAGAGGCACCAGAGGATTACTCATTATTTATAAACAGTATAG
AGGGGTTATTAAAGAAAAATGAATGCACTATATTATTTGGACATGGAACACCACACTGTTGTAATTCAGTATATGGTTGC
CTTCAAAGTATTTTAGTAGATGAAGGATATGATAATGTTTTTGTTGGAACTGTAGAAGGATATCCTACTTTTGAAACAGT
ATTAAAAAGACTAAAAAGAAAAGATATTAAAAATGTTACTTTAGTACCATTGATGGTGGTTGCAGGCGATCATGTTAAAA
ATGATATGGCATCAGATGAGGAAGATTCTTGGAAGAGTATGTTATTAAATGAGGGGATAAATGCTGAAGCATATATTCAT
GGATTAGGTGAAATAGATAAATTTTCACAACTTTATATTTCAAGAATTTATGATCTTATAGAAGATAGATATTTAAATGT
AGGAAGTACAAAAAAACTACACTGTACTTTAATATAA

Upstream 100 bases:

>100_bases
TGGGGTTTTTAACTCTTAATTTTTAATTAAAAGCGTAGAATGATAAATTTTTAATTGTGTATGAAGATAAAAAATAAATT
ATTGGAATGGAGTAACTGAT

Downstream 100 bases:

>100_bases
GAAAGAGTGTGCTTTTTTAAATTTATAAGAGGAATAAAAAATACACATTGAAATTTAAAGAAATATATATTTCAAGGTCA
TAATTATTTTTACAAAAATT

Product: sirohydrochlorin cobaltochelatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MKKAILVVSFGTSHIDALENSIERIENKIRSEFKDYEIFRAFTAHKIIKKLKNVHNLEIATPEEALEDLYRKGFEEIIVQ
PLHIIPGEEFDYIKGVAKRFEDRFSSLKLGRPIFYYQGIEEAPEDYSLFINSIEGLLKKNECTILFGHGTPHCCNSVYGC
LQSILVDEGYDNVFVGTVEGYPTFETVLKRLKRKDIKNVTLVPLMVVAGDHVKNDMASDEEDSWKSMLLNEGINAEAYIH
GLGEIDKFSQLYISRIYDLIEDRYLNVGSTKKLHCTLI

Sequences:

>Translated_278_residues
MKKAILVVSFGTSHIDALENSIERIENKIRSEFKDYEIFRAFTAHKIIKKLKNVHNLEIATPEEALEDLYRKGFEEIIVQ
PLHIIPGEEFDYIKGVAKRFEDRFSSLKLGRPIFYYQGIEEAPEDYSLFINSIEGLLKKNECTILFGHGTPHCCNSVYGC
LQSILVDEGYDNVFVGTVEGYPTFETVLKRLKRKDIKNVTLVPLMVVAGDHVKNDMASDEEDSWKSMLLNEGINAEAYIH
GLGEIDKFSQLYISRIYDLIEDRYLNVGSTKKLHCTLI
>Mature_278_residues
MKKAILVVSFGTSHIDALENSIERIENKIRSEFKDYEIFRAFTAHKIIKKLKNVHNLEIATPEEALEDLYRKGFEEIIVQ
PLHIIPGEEFDYIKGVAKRFEDRFSSLKLGRPIFYYQGIEEAPEDYSLFINSIEGLLKKNECTILFGHGTPHCCNSVYGC
LQSILVDEGYDNVFVGTVEGYPTFETVLKRLKRKDIKNVTLVPLMVVAGDHVKNDMASDEEDSWKSMLLNEGINAEAYIH
GLGEIDKFSQLYISRIYDLIEDRYLNVGSTKKLHCTLI

Specific function: Chelates cobalt to the cobalamin precursor as part of the anaerobic pathway to cobalamin biosynthesis [H]

COG id: COG4822

COG function: function code H; Cobalamin biosynthesis protein CbiK, Co2+ chelatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CbiK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010388 [H]

Pfam domain/function: PF06180 CbiK [H]

EC number: =4.99.1.3 [H]

Molecular weight: Translated: 31851; Mature: 31851

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKAILVVSFGTSHIDALENSIERIENKIRSEFKDYEIFRAFTAHKIIKKLKNVHNLEIA
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
TPEEALEDLYRKGFEEIIVQPLHIIPGEEFDYIKGVAKRFEDRFSSLKLGRPIFYYQGIE
CHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCHH
EAPEDYSLFINSIEGLLKKNECTILFGHGTPHCCNSVYGCLQSILVDEGYDNVFVGTVEG
HCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCC
YPTFETVLKRLKRKDIKNVTLVPLMVVAGDHVKNDMASDEEDSWKSMLLNEGINAEAYIH
CCCHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHCCCCCHHEEE
GLGEIDKFSQLYISRIYDLIEDRYLNVGSTKKLHCTLI
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEC
>Mature Secondary Structure
MKKAILVVSFGTSHIDALENSIERIENKIRSEFKDYEIFRAFTAHKIIKKLKNVHNLEIA
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
TPEEALEDLYRKGFEEIIVQPLHIIPGEEFDYIKGVAKRFEDRFSSLKLGRPIFYYQGIE
CHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCHH
EAPEDYSLFINSIEGLLKKNECTILFGHGTPHCCNSVYGCLQSILVDEGYDNVFVGTVEG
HCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCC
YPTFETVLKRLKRKDIKNVTLVPLMVVAGDHVKNDMASDEEDSWKSMLLNEGINAEAYIH
CCCHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHCCCCCHHEEE
GLGEIDKFSQLYISRIYDLIEDRYLNVGSTKKLHCTLI
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8501034; 11677609; 9150215; 10451360 [H]