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The map label for this gene is sdaAA [H]

Identifier: 187933422

GI number: 187933422

Start: 3215484

End: 3216362

Strand: Reverse

Name: sdaAA [H]

Synonym: CLL_A3108

Alternate gene names: 187933422

Gene position: 3216362-3215484 (Counterclockwise)

Preceding gene: 187934314

Following gene: 187933416

Centisome position: 84.63

GC content: 36.75

Gene sequence:

>879_bases
ATGCTTGCAAGAACAGGGGAAGAGTTATTAAAAATTTGTAAGGAAAATAATATATCTTTAAGTGAGTATGCTATAAGATG
TGAAGTTGAAGAAAAGGGATTAACAAGAGAAGAAGTAATAGAAAAAATGAGAAAAAATTTAAATGTTATGATATCAGCAG
CAAAGGAAGGAACAGAAAAAGAAGTATATTCTGTTAGTGGTCTTATTGGTGGAGATGGATATAAATTATATGAGTATTCA
AAATCAAAAAAAACATTAACTGGCAGAGCAACTACAATAGCTATGGCAATGGCACTTGCTTCATCAGAGGTGAATGCATC
TATGGGTAAAATAGTGGCATGTCCTACGGCGGGATCATGTGGAATACTGCCAGCAGTTATCTTAGCAGCAGGAGAAGTTC
TTGAATTAAATGAGGATGAACTTATAAAAGGACTATTAGCAGCAGCAGCAGTTGGGCTTATCATAGGACTTAATGCAACA
TTATCTGGAGCAGAAGGAGGATGCCAAGCTGAATGCGGTTCAGCATCAGCTATGGGAGCGGCAGCTGTTGTAGAAATGAT
GGGAGGAACTCCAAAGATGAGTTTAGATGCAGGTTCTATAATACTTCAAAATATATTAGGTTTAGTATGTGATCCAGTTG
CAGGTTTAGTTGAAATACCATGTGCAAAAAGAAATGCGCAAGGCGCAATAACAGCATTGTGTACAGCGGATATGGTTATG
GCTGGAATTGAAGCCAAAATACCATTTGATGAAGCTGTAATTGCTATGTATAAAGTAGGAAAAAGTTTACCATCAGCATT
AAGAGAAACTGCAATGGGTGGAATAGCAACAACGCCTACAGGCTTAAAACTTAAAAAACAAGTTTTTGGTGAAAACTAA

Upstream 100 bases:

>100_bases
ATGGATAATAAGATTAGTGAAAAAGCTATAAGAGAGATAGAAAAATTAGAGTTAGTGCATAGGATTATTTCAATAAGTCC
AGCAAAGGAAGGTGAGTAAA

Downstream 100 bases:

>100_bases
ATTAATTTATTATAATAGAGTTTCTTGATTTTTTTACATTAATGATATAATCTATATATTATAGAAAATAAAATATTAAA
TTAATAACTAGGGGTGCTGA

Product: L-serine dehydratase, iron-sulfur-dependent, alpha subunit

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MLARTGEELLKICKENNISLSEYAIRCEVEEKGLTREEVIEKMRKNLNVMISAAKEGTEKEVYSVSGLIGGDGYKLYEYS
KSKKTLTGRATTIAMAMALASSEVNASMGKIVACPTAGSCGILPAVILAAGEVLELNEDELIKGLLAAAAVGLIIGLNAT
LSGAEGGCQAECGSASAMGAAAVVEMMGGTPKMSLDAGSIILQNILGLVCDPVAGLVEIPCAKRNAQGAITALCTADMVM
AGIEAKIPFDEAVIAMYKVGKSLPSALRETAMGGIATTPTGLKLKKQVFGEN

Sequences:

>Translated_292_residues
MLARTGEELLKICKENNISLSEYAIRCEVEEKGLTREEVIEKMRKNLNVMISAAKEGTEKEVYSVSGLIGGDGYKLYEYS
KSKKTLTGRATTIAMAMALASSEVNASMGKIVACPTAGSCGILPAVILAAGEVLELNEDELIKGLLAAAAVGLIIGLNAT
LSGAEGGCQAECGSASAMGAAAVVEMMGGTPKMSLDAGSIILQNILGLVCDPVAGLVEIPCAKRNAQGAITALCTADMVM
AGIEAKIPFDEAVIAMYKVGKSLPSALRETAMGGIATTPTGLKLKKQVFGEN
>Mature_292_residues
MLARTGEELLKICKENNISLSEYAIRCEVEEKGLTREEVIEKMRKNLNVMISAAKEGTEKEVYSVSGLIGGDGYKLYEYS
KSKKTLTGRATTIAMAMALASSEVNASMGKIVACPTAGSCGILPAVILAAGEVLELNEDELIKGLLAAAAVGLIIGLNAT
LSGAEGGCQAECGSASAMGAAAVVEMMGGTPKMSLDAGSIILQNILGLVCDPVAGLVEIPCAKRNAQGAITALCTADMVM
AGIEAKIPFDEAVIAMYKVGKSLPSALRETAMGGIATTPTGLKLKKQVFGEN

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI48994925, Length=280, Percent_Identity=34.6428571428571, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1789161, Length=280, Percent_Identity=35, Blast_Score=147, Evalue=5e-37,
Organism=Escherichia coli, GI1788116, Length=284, Percent_Identity=33.0985915492958, Blast_Score=143, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005130
- InterPro:   IPR004642 [H]

Pfam domain/function: PF03313 SDH_alpha [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 30142; Mature: 30142

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
7.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLARTGEELLKICKENNISLSEYAIRCEVEEKGLTREEVIEKMRKNLNVMISAAKEGTEK
CCCCCHHHHHHHHHCCCCCHHHEEEEEEEHHHCCCHHHHHHHHHCCCEEEEEECCCCCHH
EVYSVSGLIGGDGYKLYEYSKSKKTLTGRATTIAMAMALASSEVNASMGKIVACPTAGSC
HHHHHHCEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCC
GILPAVILAAGEVLELNEDELIKGLLAAAAVGLIIGLNATLSGAEGGCQAECGSASAMGA
HHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCHHHHH
AAVVEMMGGTPKMSLDAGSIILQNILGLVCDPVAGLVEIPCAKRNAQGAITALCTADMVM
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AGIEAKIPFDEAVIAMYKVGKSLPSALRETAMGGIATTPTGLKLKKQVFGEN
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCC
>Mature Secondary Structure
MLARTGEELLKICKENNISLSEYAIRCEVEEKGLTREEVIEKMRKNLNVMISAAKEGTEK
CCCCCHHHHHHHHHCCCCCHHHEEEEEEEHHHCCCHHHHHHHHHCCCEEEEEECCCCCHH
EVYSVSGLIGGDGYKLYEYSKSKKTLTGRATTIAMAMALASSEVNASMGKIVACPTAGSC
HHHHHHCEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCC
GILPAVILAAGEVLELNEDELIKGLLAAAAVGLIIGLNATLSGAEGGCQAECGSASAMGA
HHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCHHHHH
AAVVEMMGGTPKMSLDAGSIILQNILGLVCDPVAGLVEIPCAKRNAQGAITALCTADMVM
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AGIEAKIPFDEAVIAMYKVGKSLPSALRETAMGGIATTPTGLKLKKQVFGEN
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]