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The map label for this gene is xerD [H]

Identifier: 187933384

GI number: 187933384

Start: 2459779

End: 2460657

Strand: Reverse

Name: xerD [H]

Synonym: CLL_A2368

Alternate gene names: 187933384

Gene position: 2460657-2459779 (Counterclockwise)

Preceding gene: 187932329

Following gene: 187932841

Centisome position: 64.75

GC content: 26.51

Gene sequence:

>879_bases
ATGGTAGATAGTATAAATAACTATAAAGAATATTTATTTGATAGTGGAAAAAGTGAAAATACTATATATGCTTATGTGAC
AGATGTGACATTATATCTTAAGTTTTTAGATAAGAAAGGTATAGATGTATATAAGAGCGATAAATTAACAGTTATGGCAT
ATATTCAATATTTGCTGGAGTCAGGAAAATCAGAAAGGTCTATAAATAGAATAGTTATAAGTCTTAGGAGTTTTTATTCT
TATTTAAAAAGTCAGTCATTAATAAATGAGGTACCAAAGATAGAATATAAAAGTTCTAAAAATAATAGAAAATTACCACA
AATTTTAACAGTAGATGAAGTAGATAAAATAATTAGAACAGTAGAAAAAGATTGTCCAAAAGGAATTAGAGATAATGCTC
TATTAGAGCTTATGTATGCTACTGGAATGAAGGTATCTGAGTTAATATCTTTGAATGTAGATGATATTAATTTGGAATTA
CATTTTGTAAGATGCACCGATAGTAGAAATTTTGAAAGATTAATACCTATAGGTAGAAGTGCGTGTAGAGCATTAAATGA
ATACCTTAGCATAAGATATAAAATAGCTGAATGCGGAGTGCCTAACTTATTTGTTAATTTAAATGGAAATAAACTAACAA
GACAAGGGATTTGGAGAATAGTAAAAGAATATTCTAAAAGAGCACACATAGACAAAGATGTAAATTTAAATACATTTAGA
CACTCATTTGCAGTACATTTACTTCAAAATGGTGCAAATGTAAGAGCCGTACAAAAGTTACTTGGAAATCAAGTATTAAC
ATATATGGATACTTATTATGAAATCATTAATAATGATAAAATTAATTTTATATATATGAATACACATCCAAGAGCTTGA

Upstream 100 bases:

>100_bases
ATATAGAAAATTATAAACTTAAGATATAAGTTTTAATTAAAAAGGAAAAATGATAATTTTGTCGAATATTAATTCATAAT
CAATGGTATAGGAGAGAATA

Downstream 100 bases:

>100_bases
TTTCACGCTGGATTCTATAGATTAGCTCAAAATCAAATGTAGAGAAATTTAATAAACTCCCACTATTATTCCACCTAAAA
ATTTTAATTGGTTGAAAAAT

Product: tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MVDSINNYKEYLFDSGKSENTIYAYVTDVTLYLKFLDKKGIDVYKSDKLTVMAYIQYLLESGKSERSINRIVISLRSFYS
YLKSQSLINEVPKIEYKSSKNNRKLPQILTVDEVDKIIRTVEKDCPKGIRDNALLELMYATGMKVSELISLNVDDINLEL
HFVRCTDSRNFERLIPIGRSACRALNEYLSIRYKIAECGVPNLFVNLNGNKLTRQGIWRIVKEYSKRAHIDKDVNLNTFR
HSFAVHLLQNGANVRAVQKLLGNQVLTYMDTYYEIINNDKINFIYMNTHPRA

Sequences:

>Translated_292_residues
MVDSINNYKEYLFDSGKSENTIYAYVTDVTLYLKFLDKKGIDVYKSDKLTVMAYIQYLLESGKSERSINRIVISLRSFYS
YLKSQSLINEVPKIEYKSSKNNRKLPQILTVDEVDKIIRTVEKDCPKGIRDNALLELMYATGMKVSELISLNVDDINLEL
HFVRCTDSRNFERLIPIGRSACRALNEYLSIRYKIAECGVPNLFVNLNGNKLTRQGIWRIVKEYSKRAHIDKDVNLNTFR
HSFAVHLLQNGANVRAVQKLLGNQVLTYMDTYYEIINNDKINFIYMNTHPRA
>Mature_292_residues
MVDSINNYKEYLFDSGKSENTIYAYVTDVTLYLKFLDKKGIDVYKSDKLTVMAYIQYLLESGKSERSINRIVISLRSFYS
YLKSQSLINEVPKIEYKSSKNNRKLPQILTVDEVDKIIRTVEKDCPKGIRDNALLELMYATGMKVSELISLNVDDINLEL
HFVRCTDSRNFERLIPIGRSACRALNEYLSIRYKIAECGVPNLFVNLNGNKLTRQGIWRIVKEYSKRAHIDKDVNLNTFR
HSFAVHLLQNGANVRAVQKLLGNQVLTYMDTYYEIINNDKINFIYMNTHPRA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=278, Percent_Identity=31.294964028777, Blast_Score=158, Evalue=4e-40,
Organism=Escherichia coli, GI1790244, Length=273, Percent_Identity=26.3736263736264, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1790767, Length=190, Percent_Identity=23.6842105263158, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33913; Mature: 33913

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDSINNYKEYLFDSGKSENTIYAYVTDVTLYLKFLDKKGIDVYKSDKLTVMAYIQYLLE
CCCCHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHH
SGKSERSINRIVISLRSFYSYLKSQSLINEVPKIEYKSSKNNRKLPQILTVDEVDKIIRT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCEECHHHHHHHHHH
VEKDCPKGIRDNALLELMYATGMKVSELISLNVDDINLELHFVRCTDSRNFERLIPIGRS
HHHHCCCCCCCHHHHHHHHHCCCCHHHHHCCCCCEEEEEEEEEEECCCCCCHHHCCCCHH
ACRALNEYLSIRYKIAECGVPNLFVNLNGNKLTRQGIWRIVKEYSKRAHIDKDVNLNTFR
HHHHHHHHHHEEEEHHHCCCCEEEEEECCCEEHHHHHHHHHHHHHHHHCCCCCCCHHHHH
HSFAVHLLQNGANVRAVQKLLGNQVLTYMDTYYEIINNDKINFIYMNTHPRA
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCC
>Mature Secondary Structure
MVDSINNYKEYLFDSGKSENTIYAYVTDVTLYLKFLDKKGIDVYKSDKLTVMAYIQYLLE
CCCCHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHH
SGKSERSINRIVISLRSFYSYLKSQSLINEVPKIEYKSSKNNRKLPQILTVDEVDKIIRT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCEECHHHHHHHHHH
VEKDCPKGIRDNALLELMYATGMKVSELISLNVDDINLELHFVRCTDSRNFERLIPIGRS
HHHHCCCCCCCHHHHHHHHHCCCCHHHHHCCCCCEEEEEEEEEEECCCCCCHHHCCCCHH
ACRALNEYLSIRYKIAECGVPNLFVNLNGNKLTRQGIWRIVKEYSKRAHIDKDVNLNTFR
HHHHHHHHHHEEEEHHHCCCCEEEEEECCCEEHHHHHHHHHHHHHHHHCCCCCCCHHHHH
HSFAVHLLQNGANVRAVQKLLGNQVLTYMDTYYEIINNDKINFIYMNTHPRA
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]