Click here to switch to the map view.

The map label for this gene is hprK [H]

Identifier: 187933337

GI number: 187933337

Start: 2920665

End: 2921579

Strand: Reverse

Name: hprK [H]

Synonym: CLL_A2846

Alternate gene names: 187933337

Gene position: 2921579-2920665 (Counterclockwise)

Preceding gene: 187932751

Following gene: 187934326

Centisome position: 76.88

GC content: 29.73

Gene sequence:

>915_bases
GTGGCGGTTTCGGTTAAAAGATTAATAAACGATTTTGATTTAGAAGTATTAGTTGAAGGAAACGAAGATATAAAAATCGA
AGTAAATGATGTGAATAGACCAGGCTTACAATTAGCAGGATTTTATAACTATTTTGCGCCAGAAAGAATACAAATTATAG
GTAAAGCTGAATGGAGCTTCTTACAAGATATGCAAATTGAAGTAAGAAAGAAAAGAGTTAAAAAATATTTAAGCTTTAAT
ATAACTTGTTTAATAATAAGTAGAGATTTAGAACCTCATGAAGAATTTATTAAAGAAGCAAGAAAGAATAATATATGGGT
ATTAAGAAGTAAGTCGGTAACAACAAAACTTATAAGTAAAATAACATTATATCTAGCAGATAAATTAGCTCCAGAAACTA
GATTACACGGGGTATTAGTTGATGTTTCAGGAATTGGAATATTAATAACAGGAGAAAGTGGTATAGGAAAAAGTGAAACA
GCCTTAGAACTTATAAAAAGGGGTCATAGATTAATAACTGATGATGCAGTTGATATTAGAGAAAGTGATGGAACATTGAT
AGGAAGTTCGCCAAAGATAACAATAGGAATGTTAGAAGTAAGGGGAATAGGAATTATTGATGTTACGCAACTTTATGGAT
TAAGTTCTGTATTAGAAGAAAAAGAAATAAAATTAATAATGCACTTTGAACACTGGAAAGATGACAATGATTATGATAGA
TTAGGTATAGACAATCAGTATATGGATATATTGGGTATACCAGTTAAAAAATTAACTGTTCCTGTTAGACCAGGAAGAAA
TATTGCTGTAATAATAGAAGCGGCAGCAGTTAACTATAGATATTCATTGATGTCTAAAATATCTCCTGTTGACATAATAG
AAAATAGAATGAGTGCAGTAAGTGATGAAGCTTAA

Upstream 100 bases:

>100_bases
ACAAAAATTAAGAAAGAGATACATAGATAATGTAAAGAAAAATTTTAGAGCACAATTAGAAGGTGTAGAACTGAAAAATA
AATAAAAGGAATGATGGAGA

Downstream 100 bases:

>100_bases
AATTTAAACTAAATTTATTTAAATATAGTGTTGATATTGTAATATGTAGCTTTTGGATAGAGGAGTTTATACTAATAGTT
TAAAAAGTAAATTGTGATAC

Product: HPr kinase/phosphorylase

Products: NA

Alternate protein names: HPrK/P; HPr(Ser) kinase/phosphorylase [H]

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MAVSVKRLINDFDLEVLVEGNEDIKIEVNDVNRPGLQLAGFYNYFAPERIQIIGKAEWSFLQDMQIEVRKKRVKKYLSFN
ITCLIISRDLEPHEEFIKEARKNNIWVLRSKSVTTKLISKITLYLADKLAPETRLHGVLVDVSGIGILITGESGIGKSET
ALELIKRGHRLITDDAVDIRESDGTLIGSSPKITIGMLEVRGIGIIDVTQLYGLSSVLEEKEIKLIMHFEHWKDDNDYDR
LGIDNQYMDILGIPVKKLTVPVRPGRNIAVIIEAAAVNYRYSLMSKISPVDIIENRMSAVSDEA

Sequences:

>Translated_304_residues
MAVSVKRLINDFDLEVLVEGNEDIKIEVNDVNRPGLQLAGFYNYFAPERIQIIGKAEWSFLQDMQIEVRKKRVKKYLSFN
ITCLIISRDLEPHEEFIKEARKNNIWVLRSKSVTTKLISKITLYLADKLAPETRLHGVLVDVSGIGILITGESGIGKSET
ALELIKRGHRLITDDAVDIRESDGTLIGSSPKITIGMLEVRGIGIIDVTQLYGLSSVLEEKEIKLIMHFEHWKDDNDYDR
LGIDNQYMDILGIPVKKLTVPVRPGRNIAVIIEAAAVNYRYSLMSKISPVDIIENRMSAVSDEA
>Mature_303_residues
AVSVKRLINDFDLEVLVEGNEDIKIEVNDVNRPGLQLAGFYNYFAPERIQIIGKAEWSFLQDMQIEVRKKRVKKYLSFNI
TCLIISRDLEPHEEFIKEARKNNIWVLRSKSVTTKLISKITLYLADKLAPETRLHGVLVDVSGIGILITGESGIGKSETA
LELIKRGHRLITDDAVDIRESDGTLIGSSPKITIGMLEVRGIGIIDVTQLYGLSSVLEEKEIKLIMHFEHWKDDNDYDRL
GIDNQYMDILGIPVKKLTVPVRPGRNIAVIIEAAAVNYRYSLMSKISPVDIIENRMSAVSDEA

Specific function: Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-pr

COG id: COG1493

COG function: function code T; Serine kinase of the HPr protein, regulates carbohydrate metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPrK/P family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003755
- InterPro:   IPR011104
- InterPro:   IPR011126 [H]

Pfam domain/function: PF07475 Hpr_kinase_C; PF02603 Hpr_kinase_N [H]

EC number: NA

Molecular weight: Translated: 34292; Mature: 34161

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVSVKRLINDFDLEVLVEGNEDIKIEVNDVNRPGLQLAGFYNYFAPERIQIIGKAEWSF
CCEEHHHHHCCCCEEEEEECCCEEEEEEECCCCCCEEEEEHHHCCCCCEEEEEECCCHHH
LQDMQIEVRKKRVKKYLSFNITCLIISRDLEPHEEFIKEARKNNIWVLRSKSVTTKLISK
HHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHH
ITLYLADKLAPETRLHGVLVDVSGIGILITGESGIGKSETALELIKRGHRLITDDAVDIR
HHHHHHHHCCCCHHHCEEEEEECCEEEEEECCCCCCCHHHHHHHHHCCCEEECCCCCEEE
ESDGTLIGSSPKITIGMLEVRGIGIIDVTQLYGLSSVLEEKEIKLIMHFEHWKDDNDYDR
CCCCEEECCCCCEEEEEEEECCCCEEEHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCC
LGIDNQYMDILGIPVKKLTVPVRPGRNIAVIIEAAAVNYRYSLMSKISPVDIIENRMSAV
CCCCCCHHHHHCCCHHHEEEECCCCCCEEEEEEEEECCHHHHHHHCCCCHHHHHHHHHHH
SDEA
CCCC
>Mature Secondary Structure 
AVSVKRLINDFDLEVLVEGNEDIKIEVNDVNRPGLQLAGFYNYFAPERIQIIGKAEWSF
CEEHHHHHCCCCEEEEEECCCEEEEEEECCCCCCEEEEEHHHCCCCCEEEEEECCCHHH
LQDMQIEVRKKRVKKYLSFNITCLIISRDLEPHEEFIKEARKNNIWVLRSKSVTTKLISK
HHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHH
ITLYLADKLAPETRLHGVLVDVSGIGILITGESGIGKSETALELIKRGHRLITDDAVDIR
HHHHHHHHCCCCHHHCEEEEEECCEEEEEECCCCCCCHHHHHHHHHCCCEEECCCCCEEE
ESDGTLIGSSPKITIGMLEVRGIGIIDVTQLYGLSSVLEEKEIKLIMHFEHWKDDNDYDR
CCCCEEECCCCCEEEEEEEECCCCEEEHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCC
LGIDNQYMDILGIPVKKLTVPVRPGRNIAVIIEAAAVNYRYSLMSKISPVDIIENRMSAV
CCCCCCHHHHHCCCHHHEEEECCCCCCEEEEEEEEECCHHHHHHHCCCCHHHHHHHHHHH
SDEA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA