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The map label for this gene is apeA [H]

Identifier: 187934326

GI number: 187934326

Start: 2919097

End: 2920488

Strand: Reverse

Name: apeA [H]

Synonym: CLL_A2845

Alternate gene names: 187934326

Gene position: 2920488-2919097 (Counterclockwise)

Preceding gene: 187933337

Following gene: 187933058

Centisome position: 76.85

GC content: 30.17

Gene sequence:

>1392_bases
ATGAAATCAGAAAAAAATAACAAGAATGTATGGAATAAATATGAGGAAAAGGGCGTAAAAGAAATCTTTGATTTTTGTGA
TGGATACAAAAATTTTATGTCTATATGCAAGACTGAAAGAGAATGTGTAAAAGAAGTTATTAAAATGGCTGAAGATAATG
GCTATAAAAATATTGATGACATAATAAAAAATGGTGGAGCTTTAAAAGCAGGAGATAAGGTATATGCTAATAATAAAGGA
AAGACAATTGCTTTATTTATTATCGGAAATGAATCTATGGAAAAAGGTCTTAAAATTTTAGGAGCTCACATTGATTCACC
TAGATTAGATGCAAAACAAAATCCACTTTATGAAGATAATGAAATGGTATTATTAGATACTCATTATTATGGTGGAATTA
AAAAATATCAATGGGTTACTTTACCGTTAGCTTTACATGGAGTAGTGGTAAAAAAAGATGGTTCAATAATTGATATTTGT
ATTGGTGAAGATGAAAATGATCCAGTTGTGGGAGTATCAGATTTATTAGTACATTTATCTGGAGATCAATTACTTAAAAA
AGGAAATAAAGTAGTTGAAGGAGAAGATTTAAATGTATTAGTTGGTAGCATGCCTTTAAAAGGAGAAGAAAAAGATGCTG
TAAAAGCTAATATATTAAAAATATTAAAAGAAAAATATGATTTTGAAGAAGAAGATTTCTTATCAGCTGAAATTGAAATA
GTTCCAGCAGGAAAAGCAAGGGATTATGGCTTAGATAGAAGTATGGTTATGGCTTATGGTCATGATGATAGAGTATGTTC
ATATACTTCATTAAAGGCTATGTTTGATATTAATGAATGTGATAAGACTTGTTGTTGTCTTTTAGTTGATAAAGAAGAAG
TAGGTAGTATAGGAGCAACTGGAATGCAATCTAAATTCTTTGAAAATATAGTTGCAGAAGTTCTTGATAAAGTTGAAGGA
TTCTCAGATATTAAATTAAGAAGATGTCTTAGCAATTCTAAAATGTTATCTTCTGATGTAAGTGCAGCTTTTGATCCAAA
TTATCCATCAGTAATGGAAAAGAAAAATTCAGCATTCTTTGGTAGAGGTATGGTATTTAACAAATATACTGGAGCTAGAG
GAAAATCAGGATGTAATGATGCAAATGCAGAATATATGGCTGAACTTAGAAGAATAATGGAAAAACATGATGTTTCTATT
CAAACAGCAGAACTAGGAAAAGTTGATGCTGGTGGTGGTGGAACTATCGCATATATTTTAGCTCAATACAATATGGAAGT
TATAGACTGTGGAGTAGCACTTTTAAATATGCATGCACCATGGGAATTAGCAAGCAAAGCAGATATATATGAAACTATGA
GAGGCTACAGAGCTTTCTTAATAGAAGCATAG

Upstream 100 bases:

>100_bases
AGTTTAAAAAGTAAATTGTGATACAATTATGCAACTATATTAAAATATCAACATTTTTTCAAAACAAAATTTATTAAAAA
GAGAGAAGAGAGGATTAAAT

Downstream 100 bases:

>100_bases
AAATAAAAATTTTAATTAAAGGTTTTGTTTTTAATATGTGTTGATATATACAATAAGTATAGTGACATTGTAATTGGACT
TTGAGAATCCTTAATGAGTA

Product: aminopeptidase 1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MKSEKNNKNVWNKYEEKGVKEIFDFCDGYKNFMSICKTERECVKEVIKMAEDNGYKNIDDIIKNGGALKAGDKVYANNKG
KTIALFIIGNESMEKGLKILGAHIDSPRLDAKQNPLYEDNEMVLLDTHYYGGIKKYQWVTLPLALHGVVVKKDGSIIDIC
IGEDENDPVVGVSDLLVHLSGDQLLKKGNKVVEGEDLNVLVGSMPLKGEEKDAVKANILKILKEKYDFEEEDFLSAEIEI
VPAGKARDYGLDRSMVMAYGHDDRVCSYTSLKAMFDINECDKTCCCLLVDKEEVGSIGATGMQSKFFENIVAEVLDKVEG
FSDIKLRRCLSNSKMLSSDVSAAFDPNYPSVMEKKNSAFFGRGMVFNKYTGARGKSGCNDANAEYMAELRRIMEKHDVSI
QTAELGKVDAGGGGTIAYILAQYNMEVIDCGVALLNMHAPWELASKADIYETMRGYRAFLIEA

Sequences:

>Translated_463_residues
MKSEKNNKNVWNKYEEKGVKEIFDFCDGYKNFMSICKTERECVKEVIKMAEDNGYKNIDDIIKNGGALKAGDKVYANNKG
KTIALFIIGNESMEKGLKILGAHIDSPRLDAKQNPLYEDNEMVLLDTHYYGGIKKYQWVTLPLALHGVVVKKDGSIIDIC
IGEDENDPVVGVSDLLVHLSGDQLLKKGNKVVEGEDLNVLVGSMPLKGEEKDAVKANILKILKEKYDFEEEDFLSAEIEI
VPAGKARDYGLDRSMVMAYGHDDRVCSYTSLKAMFDINECDKTCCCLLVDKEEVGSIGATGMQSKFFENIVAEVLDKVEG
FSDIKLRRCLSNSKMLSSDVSAAFDPNYPSVMEKKNSAFFGRGMVFNKYTGARGKSGCNDANAEYMAELRRIMEKHDVSI
QTAELGKVDAGGGGTIAYILAQYNMEVIDCGVALLNMHAPWELASKADIYETMRGYRAFLIEA
>Mature_463_residues
MKSEKNNKNVWNKYEEKGVKEIFDFCDGYKNFMSICKTERECVKEVIKMAEDNGYKNIDDIIKNGGALKAGDKVYANNKG
KTIALFIIGNESMEKGLKILGAHIDSPRLDAKQNPLYEDNEMVLLDTHYYGGIKKYQWVTLPLALHGVVVKKDGSIIDIC
IGEDENDPVVGVSDLLVHLSGDQLLKKGNKVVEGEDLNVLVGSMPLKGEEKDAVKANILKILKEKYDFEEEDFLSAEIEI
VPAGKARDYGLDRSMVMAYGHDDRVCSYTSLKAMFDINECDKTCCCLLVDKEEVGSIGATGMQSKFFENIVAEVLDKVEG
FSDIKLRRCLSNSKMLSSDVSAAFDPNYPSVMEKKNSAFFGRGMVFNKYTGARGKSGCNDANAEYMAELRRIMEKHDVSI
QTAELGKVDAGGGGTIAYILAQYNMEVIDCGVALLNMHAPWELASKADIYETMRGYRAFLIEA

Specific function: Unknown

COG id: COG1362

COG function: function code E; Aspartyl aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M18 family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17552916, Length=409, Percent_Identity=22.7383863080685, Blast_Score=86, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6321905, Length=477, Percent_Identity=22.6415094339623, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6322746, Length=398, Percent_Identity=24.1206030150754, Blast_Score=91, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022983
- InterPro:   IPR001948 [H]

Pfam domain/function: PF02127 Peptidase_M18 [H]

EC number: NA

Molecular weight: Translated: 51454; Mature: 51454

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSEKNNKNVWNKYEEKGVKEIFDFCDGYKNFMSICKTERECVKEVIKMAEDNGYKNIDD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
IIKNGGALKAGDKVYANNKGKTIALFIIGNESMEKGLKILGAHIDSPRLDAKQNPLYEDN
HHHCCCCCCCCCEEEECCCCCEEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
EMVLLDTHYYGGIKKYQWVTLPLALHGVVVKKDGSIIDICIGEDENDPVVGVSDLLVHLS
CEEEEEECCCCCCCEEEEEEEEEEEEEEEEECCCCEEEEEECCCCCCCEEEHHHHHEECC
GDQLLKKGNKVVEGEDLNVLVGSMPLKGEEKDAVKANILKILKEKYDFEEEDFLSAEIEI
CHHHHHCCCCEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
VPAGKARDYGLDRSMVMAYGHDDRVCSYTSLKAMFDINECDKTCCCLLVDKEEVGSIGAT
EECCCCCCCCCCCCEEEEECCCCCEEEHHHHHHEECCCHHCCEEEEEEECHHHHCCCCCC
GMQSKFFENIVAEVLDKVEGFSDIKLRRCLSNSKMLSSDVSAAFDPNYPSVMEKKNSAFF
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHCCCCCCCCCCHHHHHCCCCCEE
GRGMVFNKYTGARGKSGCNDANAEYMAELRRIMEKHDVSIQTAELGKVDAGGGGTIAYIL
ECCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCEECCCCCEEEEEE
AQYNMEVIDCGVALLNMHAPWELASKADIYETMRGYRAFLIEA
ECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEEECC
>Mature Secondary Structure
MKSEKNNKNVWNKYEEKGVKEIFDFCDGYKNFMSICKTERECVKEVIKMAEDNGYKNIDD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
IIKNGGALKAGDKVYANNKGKTIALFIIGNESMEKGLKILGAHIDSPRLDAKQNPLYEDN
HHHCCCCCCCCCEEEECCCCCEEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
EMVLLDTHYYGGIKKYQWVTLPLALHGVVVKKDGSIIDICIGEDENDPVVGVSDLLVHLS
CEEEEEECCCCCCCEEEEEEEEEEEEEEEEECCCCEEEEEECCCCCCCEEEHHHHHEECC
GDQLLKKGNKVVEGEDLNVLVGSMPLKGEEKDAVKANILKILKEKYDFEEEDFLSAEIEI
CHHHHHCCCCEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
VPAGKARDYGLDRSMVMAYGHDDRVCSYTSLKAMFDINECDKTCCCLLVDKEEVGSIGAT
EECCCCCCCCCCCCEEEEECCCCCEEEHHHHHHEECCCHHCCEEEEEEECHHHHCCCCCC
GMQSKFFENIVAEVLDKVEGFSDIKLRRCLSNSKMLSSDVSAAFDPNYPSVMEKKNSAFF
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHCCCCCCCCCCHHHHHCCCCCEE
GRGMVFNKYTGARGKSGCNDANAEYMAELRRIMEKHDVSIQTAELGKVDAGGGGTIAYIL
ECCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCEECCCCCEEEEEE
AQYNMEVIDCGVALLNMHAPWELASKADIYETMRGYRAFLIEA
ECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]