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The map label for this gene is cbiC [H]

Identifier: 187933185

GI number: 187933185

Start: 3018009

End: 3018632

Strand: Reverse

Name: cbiC [H]

Synonym: CLL_A2937

Alternate gene names: 187933185

Gene position: 3018632-3018009 (Counterclockwise)

Preceding gene: 187933062

Following gene: 187935411

Centisome position: 79.43

GC content: 31.09

Gene sequence:

>624_bases
ATGGATTATTTGAAAAATCCTATGGGGATTGAAGAAAAAAGTTTTGAGATAATAGGTGAGGAATTAGGAGCACATTCTTT
TTCTGATGAAGAACTTTTAATTGTTAAAAGAGTTATACATACAACAGCTGATTTTGAATATAAAGATTTAGTTGAAATAA
GTAAAGATGCTATAAATGCAGGCAAAGAAGTTTTATCTAAAGGTGCCACAATATATACGGATACTAATATGGCATTAAAT
GGTATAAATAAGATGGCATTAGCTAAAACAAATAGTAAGGTAATTTGTTATGTAAATGAACCAGATGTTCATATTGAAGC
AAAGGAAAAAGGTATTACTAGAAGCATGGCAGCAGTTGAAAAGGCTTGTAGTGATGATGTAGATATATTTGTGTTTGGAA
ATGCGCCTACAGCATTATTTAAACTTAAGGAACTTATTAAAGAAAAAAAAGCAAATCCTAAGCTTATAATAGCAGTGCCA
GTAGGATTCGTTGGAGCAGCTGAAAGCAAAGAAAATTTAGATGAACTAGGAATTCCATATATAAGAGTAAAGGGAAGAAA
AGGTGGAAGTACAGTTGGAGCTGCAATTGTAAATGCACTTTTGTATATGATTGTTAAAAGATAG

Upstream 100 bases:

>100_bases
AATAAATAGATAAATAAATTAATTAAATAGCATAACTTTATTTAATTGTAGAAGAACATTTGTAAATAAGAAAATTTTAT
ATAGAAGAGAAGGAGAGCGT

Downstream 100 bases:

>100_bases
TGAAAAAGATTAAAAATGAAGTAAACATATTAAATCATATTTACACTCCATTAGCGCTGGCTTTTGGAATTAGCTTTTTT
GACTTGTTATGGGAAAATAT

Product: precorrin-8X methylmutase

Products: hydrogenobyrinate

Alternate protein names: Cobalt-precorrin isomerase; HBA synthase [H]

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MDYLKNPMGIEEKSFEIIGEELGAHSFSDEELLIVKRVIHTTADFEYKDLVEISKDAINAGKEVLSKGATIYTDTNMALN
GINKMALAKTNSKVICYVNEPDVHIEAKEKGITRSMAAVEKACSDDVDIFVFGNAPTALFKLKELIKEKKANPKLIIAVP
VGFVGAAESKENLDELGIPYIRVKGRKGGSTVGAAIVNALLYMIVKR

Sequences:

>Translated_207_residues
MDYLKNPMGIEEKSFEIIGEELGAHSFSDEELLIVKRVIHTTADFEYKDLVEISKDAINAGKEVLSKGATIYTDTNMALN
GINKMALAKTNSKVICYVNEPDVHIEAKEKGITRSMAAVEKACSDDVDIFVFGNAPTALFKLKELIKEKKANPKLIIAVP
VGFVGAAESKENLDELGIPYIRVKGRKGGSTVGAAIVNALLYMIVKR
>Mature_207_residues
MDYLKNPMGIEEKSFEIIGEELGAHSFSDEELLIVKRVIHTTADFEYKDLVEISKDAINAGKEVLSKGATIYTDTNMALN
GINKMALAKTNSKVICYVNEPDVHIEAKEKGITRSMAAVEKACSDDVDIFVFGNAPTALFKLKELIKEKKANPKLIIAVP
VGFVGAAESKENLDELGIPYIRVKGRKGGSTVGAAIVNALLYMIVKR

Specific function: Catalyzes the conversion of cobalt-precorrin-8X to cobyrinic acid; a methyl migration reaction during the transformation of cobalt-precorrin-3 to form cobyrinic acid [H]

COG id: COG2082

COG function: function code H; Precorrin isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003722 [H]

Pfam domain/function: PF02570 CbiC [H]

EC number: 5.4.1.2

Molecular weight: Translated: 22607; Mature: 22607

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYLKNPMGIEEKSFEIIGEELGAHSFSDEELLIVKRVIHTTADFEYKDLVEISKDAINA
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
GKEVLSKGATIYTDTNMALNGINKMALAKTNSKVICYVNEPDVHIEAKEKGITRSMAAVE
HHHHHHCCCEEEEECCHHHHCCCCEEEEECCCEEEEEECCCCEEEEECCCCHHHHHHHHH
KACSDDVDIFVFGNAPTALFKLKELIKEKKANPKLIIAVPVGFVGAAESKENLDELGIPY
HHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEECCCCEECCCCCCCHHHHCCCE
IRVKGRKGGSTVGAAIVNALLYMIVKR
EEEECCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDYLKNPMGIEEKSFEIIGEELGAHSFSDEELLIVKRVIHTTADFEYKDLVEISKDAINA
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
GKEVLSKGATIYTDTNMALNGINKMALAKTNSKVICYVNEPDVHIEAKEKGITRSMAAVE
HHHHHHCCCEEEEECCHHHHCCCCEEEEECCCEEEEEECCCCEEEEECCCCHHHHHHHHH
KACSDDVDIFVFGNAPTALFKLKELIKEKKANPKLIIAVPVGFVGAAESKENLDELGIPY
HHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEECCCCEECCCCCCCHHHHCCCE
IRVKGRKGGSTVGAAIVNALLYMIVKR
EEEECCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Precorrin 8X

Specific reaction: precorrin-8X = hydrogenobyrinate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8501034; 11677609; 1451790 [H]