Click here to switch to the map view.

The map label for this gene is cobB [H]

Identifier: 187933062

GI number: 187933062

Start: 3018720

End: 3020036

Strand: Reverse

Name: cobB [H]

Synonym: CLL_A2938

Alternate gene names: 187933062

Gene position: 3020036-3018720 (Counterclockwise)

Preceding gene: 187934982

Following gene: 187933185

Centisome position: 79.47

GC content: 26.58

Gene sequence:

>1317_bases
TTGAAATCTATAATTATTTCATCTAATTGTAGTGGTGGAGGGAAAACAACTTTTACTTTAGGAATTATGAAAGCATTGAA
GGATAAAGGGTTAAAAGTTCAAGGATATAAAGTAGGACCAGATTATATAGATACAGCTTTTCATAAAGAAGCTACAGGAG
TAGAATCTAGAAATCTTGATACATTTTTAATGGGTAAAGATGGTGTTAAAAGGAGCTACTTTAAAGGAAATGGTGATGTC
GGAATAATTGAAGGGGCAATGGGATTATACGATGGAGTAGGAGCAACAACACAGTCTTCAACTTATGATATTTCTAAGAC
CTTAGGAAACATGTCAATAATTTTAGTGCTTTCACCTAAAGGACAAAGTTCAACACTATGTGCAGAAATAAATGGTCTTA
AGAATTATAGACACGCTAATATTGTTGGTGTTGTATTAAACTGTATAAGTGAAAAATATTATAAACTTTTAAAATATTCT
ATAGAAAAAAATTGTAATATAAAAGTATTTGGATATGTTCCTAAAAATGAAGAAGTAAAAATTTCTAGCAGACATTTAGG
TCTTGTACAAAGTTCAGAAATAGAAAATTTACAAAATAAATTAGAATTATGTAGTGAGTTAATAAGTGAATATATTAATT
TAGATGGTATTTTAGAGGTTATGTCAGAAGTTAAATGTGATAATAGCAATAATAAAGTAGAACTTAATATAAAAAATAGA
AACTTAAATATTGCAATAGCATTAGATAAAGCATTTAGCTTTTACTATAAAGATAATATAGAACTTTTAAAATCTATTGG
AAATATAACATATTTTAGTCCTATTAATGATGATAAGTTACCAGACAATGTAGATTTTTTATATATAGGTGGAGGATATC
CAGAAGTTTTTAAAGAAGAATTATCTAAGAATCTATCTATGAGAAAAAGTATTAAAGAGGCATTAGATTCTGGCTTAAGA
TGTTATGCAGAATGTGGTGGTCTTATGTATTTGACAGAAGAAATTGATGGATATGAGATGGTTGGCTTTTTTAATGGAAA
AAGTGAAATGACTAAAGGACTTAAAAGATTTGGATATTGTACAGTAAATATAGATGAAAAATATTTAGGTCAGGAAATTA
AAATAAATGCTCATGAGTTTCATAAATCAGATGTTAGCTTAAATGAGAATAAAATATATAACATTGAAAAAACACAATAT
GATGGTGAAAAGATAACTTGGGAATGTGGATATTTAAAAAATAACACATTAGCAGGTTATGCACATATTAATTTCTTGGG
AAATATTAAATTATTAGAAAACTTAATAAATAGATAA

Upstream 100 bases:

>100_bases
CATAATTATTTTTACAAAAATTACTAAATATCAATTAAAAAATATTACATAGTCAGTTGGATTTTAGGTAATATAATAAA
TCAAGAAAGGGGGAAATAAT

Downstream 100 bases:

>100_bases
ATAAATTAATTAAATAGCATAACTTTATTTAATTGTAGAAGAACATTTGTAAATAAGAAAATTTTATATAGAAGAGAAGG
AGAGCGTATGGATTATTTGA

Product: cobyrinic acid a,c-diamide synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MKSIIISSNCSGGGKTTFTLGIMKALKDKGLKVQGYKVGPDYIDTAFHKEATGVESRNLDTFLMGKDGVKRSYFKGNGDV
GIIEGAMGLYDGVGATTQSSTYDISKTLGNMSIILVLSPKGQSSTLCAEINGLKNYRHANIVGVVLNCISEKYYKLLKYS
IEKNCNIKVFGYVPKNEEVKISSRHLGLVQSSEIENLQNKLELCSELISEYINLDGILEVMSEVKCDNSNNKVELNIKNR
NLNIAIALDKAFSFYYKDNIELLKSIGNITYFSPINDDKLPDNVDFLYIGGGYPEVFKEELSKNLSMRKSIKEALDSGLR
CYAECGGLMYLTEEIDGYEMVGFFNGKSEMTKGLKRFGYCTVNIDEKYLGQEIKINAHEFHKSDVSLNENKIYNIEKTQY
DGEKITWECGYLKNNTLAGYAHINFLGNIKLLENLINR

Sequences:

>Translated_438_residues
MKSIIISSNCSGGGKTTFTLGIMKALKDKGLKVQGYKVGPDYIDTAFHKEATGVESRNLDTFLMGKDGVKRSYFKGNGDV
GIIEGAMGLYDGVGATTQSSTYDISKTLGNMSIILVLSPKGQSSTLCAEINGLKNYRHANIVGVVLNCISEKYYKLLKYS
IEKNCNIKVFGYVPKNEEVKISSRHLGLVQSSEIENLQNKLELCSELISEYINLDGILEVMSEVKCDNSNNKVELNIKNR
NLNIAIALDKAFSFYYKDNIELLKSIGNITYFSPINDDKLPDNVDFLYIGGGYPEVFKEELSKNLSMRKSIKEALDSGLR
CYAECGGLMYLTEEIDGYEMVGFFNGKSEMTKGLKRFGYCTVNIDEKYLGQEIKINAHEFHKSDVSLNENKIYNIEKTQY
DGEKITWECGYLKNNTLAGYAHINFLGNIKLLENLINR
>Mature_438_residues
MKSIIISSNCSGGGKTTFTLGIMKALKDKGLKVQGYKVGPDYIDTAFHKEATGVESRNLDTFLMGKDGVKRSYFKGNGDV
GIIEGAMGLYDGVGATTQSSTYDISKTLGNMSIILVLSPKGQSSTLCAEINGLKNYRHANIVGVVLNCISEKYYKLLKYS
IEKNCNIKVFGYVPKNEEVKISSRHLGLVQSSEIENLQNKLELCSELISEYINLDGILEVMSEVKCDNSNNKVELNIKNR
NLNIAIALDKAFSFYYKDNIELLKSIGNITYFSPINDDKLPDNVDFLYIGGGYPEVFKEELSKNLSMRKSIKEALDSGLR
CYAECGGLMYLTEEIDGYEMVGFFNGKSEMTKGLKRFGYCTVNIDEKYLGQEIKINAHEFHKSDVSLNENKIYNIEKTQY
DGEKITWECGYLKNNTLAGYAHINFLGNIKLLENLINR

Specific function: Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]

COG id: COG1797

COG function: function code H; Cobyrinic acid a,c-diamide synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR004484
- InterPro:   IPR017929
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: NA

Molecular weight: Translated: 48998; Mature: 48998

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSIIISSNCSGGGKTTFTLGIMKALKDKGLKVQGYKVGPDYIDTAFHKEATGVESRNLD
CCEEEEECCCCCCCCEEHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHCCCCCCCCC
TFLMGKDGVKRSYFKGNGDVGIIEGAMGLYDGVGATTQSSTYDISKTLGNMSIILVLSPK
EEEECCCCCCCCEECCCCCEEEEECCHHHHCCCCCCCCCCCEEHHHCCCCEEEEEEECCC
GQSSTLCAEINGLKNYRHANIVGVVLNCISEKYYKLLKYSIEKNCNIKVFGYVPKNEEVK
CCCCEEEEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEE
ISSRHLGLVQSSEIENLQNKLELCSELISEYINLDGILEVMSEVKCDNSNNKVELNIKNR
EECCEECCEEHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCEEEEEEECC
NLNIAIALDKAFSFYYKDNIELLKSIGNITYFSPINDDKLPDNVDFLYIGGGYPEVFKEE
CEEEEEEEECEEEEEECCCHHHHHHHCCEEEECCCCCCCCCCCCCEEEECCCCHHHHHHH
LSKNLSMRKSIKEALDSGLRCYAECGGLMYLTEEIDGYEMVGFFNGKSEMTKGLKRFGYC
HHHCHHHHHHHHHHHHHHHEEHHHCCCEEEEEECCCCEEEEEEECCHHHHHHHHHHHCEE
TVNIDEKYLGQEIKINAHEFHKSDVSLNENKIYNIEKTQYDGEKITWECGYLKNNTLAGY
EEECCHHHCCCEEEEEHHHHCCCCCCCCCCEEEEEECCCCCCCEEEEEECCEECCCEEEE
AHINFLGNIKLLENLINR
EEEEEECCHHHHHHHHCC
>Mature Secondary Structure
MKSIIISSNCSGGGKTTFTLGIMKALKDKGLKVQGYKVGPDYIDTAFHKEATGVESRNLD
CCEEEEECCCCCCCCEEHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHCCCCCCCCC
TFLMGKDGVKRSYFKGNGDVGIIEGAMGLYDGVGATTQSSTYDISKTLGNMSIILVLSPK
EEEECCCCCCCCEECCCCCEEEEECCHHHHCCCCCCCCCCCEEHHHCCCCEEEEEEECCC
GQSSTLCAEINGLKNYRHANIVGVVLNCISEKYYKLLKYSIEKNCNIKVFGYVPKNEEVK
CCCCEEEEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEE
ISSRHLGLVQSSEIENLQNKLELCSELISEYINLDGILEVMSEVKCDNSNNKVELNIKNR
EECCEECCEEHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCEEEEEEECC
NLNIAIALDKAFSFYYKDNIELLKSIGNITYFSPINDDKLPDNVDFLYIGGGYPEVFKEE
CEEEEEEEECEEEEEECCCHHHHHHHCCEEEECCCCCCCCCCCCCEEEECCCCHHHHHHH
LSKNLSMRKSIKEALDSGLRCYAECGGLMYLTEEIDGYEMVGFFNGKSEMTKGLKRFGYC
HHHCHHHHHHHHHHHHHHHEEHHHCCCEEEEEECCCCEEEEEEECCHHHHHHHHHHHCEE
TVNIDEKYLGQEIKINAHEFHKSDVSLNENKIYNIEKTQYDGEKITWECGYLKNNTLAGY
EEECCHHHCCCEEEEEHHHHCCCCCCCCCCEEEEEECCCCCCCEEEEEECCEECCCEEEE
AHINFLGNIKLLENLINR
EEEEEECCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]