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The map label for this gene is cat2 [H]

Identifier: 187933037

GI number: 187933037

Start: 802552

End: 803847

Strand: Reverse

Name: cat2 [H]

Synonym: CLL_A0786

Alternate gene names: 187933037

Gene position: 803847-802552 (Counterclockwise)

Preceding gene: 187933920

Following gene: 187934004

Centisome position: 21.15

GC content: 31.79

Gene sequence:

>1296_bases
ATGAATTATTCAGAACAATTAAAAAACAAAATTATAACTGTAGAAAAAGCCTTATCACTTGTAAAATCAAATGATGAAAT
AGTTACTTCATTAGGACCTTGTGAAGCAACATTATTTATGTCAAGGCTTCATGAAATAAGAGACAGAGTAGAAAATGTAA
CTGTAGTTAGTATGCTTAGTGCTTTAGATTATAAATATCATACAGATCCAAGTATGGCTGGACACTTTATAAATGAATCT
ACATTTTTTGCTGGACCAGCTAGAAAAGCTCATTCAACAGGTTTAGTTTCATATATACCAACTCATCTTAGATACGCTGG
TATCAACAGACTTGATTATAAAACACCTAATATATTTATTGGTGCTGTCACTCCAATGGACAAGCATGGTTTCTTCTCAT
TATCACTTTCTACTGTATATGAAAGAGATTCATTGGAAAAAGCCGATGTAGTTATATTTGAAGTAAATAAAAATTTACCT
AGAATATTTGGAGATACTTCAGTTCATATAAGCCAAGTAGATTATGTGTATGAAAGTAATGAAAAAGTACCAGAATTATC
TCCTAAGGAACCTTCTGAAAAGGATTTTATAATTGGCCAATATATAGCAGATTTAGTAGATGACGGTGCTACTATTCAGC
TTGGAATTGGTGGAATTCCAAATGCTGTTGCTAAATCATTAATGACAAAAAAAGACTTAGGAATACACACTGAAATGATT
ACTGAAGGTGTAGTTGATTTATTTGAAGCTGGAGTTGTTAACAATAGTAAAAAAACTCTTCATAAAAATAAAATCATAGG
CGCTTTCGCATTCGGTTCTCAAAGGTTATATGACTTTTTAGATGATAATCCTTGTATTGAAATGAAGAGATGCTCTTATG
TAAATAATCCATATACTTTAGCTAAAAATAATAAGATGACATCTATAAACACATCTCTTTCTGTAGATTTAACTGGTCAA
TGTGCTTCTGAAAGCTTAGGCTTTAAACAATACAGTGGAACTGGTGGACAAACTGACACAGGAATTGGTGCACAAATGAG
TCCTGGTGGAAAATCTATAATTGCTTTATACTCAACTGCTAAGAATGGTACTATTTCTAGTATTGTGCCTAGTCATTATA
TGGGTGCAGCTATTACATATTCTAGAAATGATGTTCAATATATTGTTACTGAATATGGAGTTGCTAACCTTCGTGGAAAA
AGTATTAAAGAAAGAGTTGATAGCTTAATTGCTATAGCTCACCCTGACTTTAGACAAGAACTTAAGAAGGAAGCTGTTAA
GAATAGAATTTGGTAG

Upstream 100 bases:

>100_bases
TTATATTAGATATTGACAACTTTTACATTGCAAAAGCAAACGTTTTTTTATAAATTTATTTGTTAATAAAATAACATACG
TTAACTAGGAGGATATGTTT

Downstream 100 bases:

>100_bases
AATAAAATTTGGTAAAGGAAGTGCTAATTATGGATGATAAAAGTAAATTAAAGGAAATCCTAAGCAAATTGGATTCTATT
AACAATAAGGTTAATAATAT

Product: 4-hydroxybutyrate coenzyme A transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MNYSEQLKNKIITVEKALSLVKSNDEIVTSLGPCEATLFMSRLHEIRDRVENVTVVSMLSALDYKYHTDPSMAGHFINES
TFFAGPARKAHSTGLVSYIPTHLRYAGINRLDYKTPNIFIGAVTPMDKHGFFSLSLSTVYERDSLEKADVVIFEVNKNLP
RIFGDTSVHISQVDYVYESNEKVPELSPKEPSEKDFIIGQYIADLVDDGATIQLGIGGIPNAVAKSLMTKKDLGIHTEMI
TEGVVDLFEAGVVNNSKKTLHKNKIIGAFAFGSQRLYDFLDDNPCIEMKRCSYVNNPYTLAKNNKMTSINTSLSVDLTGQ
CASESLGFKQYSGTGGQTDTGIGAQMSPGGKSIIALYSTAKNGTISSIVPSHYMGAAITYSRNDVQYIVTEYGVANLRGK
SIKERVDSLIAIAHPDFRQELKKEAVKNRIW

Sequences:

>Translated_431_residues
MNYSEQLKNKIITVEKALSLVKSNDEIVTSLGPCEATLFMSRLHEIRDRVENVTVVSMLSALDYKYHTDPSMAGHFINES
TFFAGPARKAHSTGLVSYIPTHLRYAGINRLDYKTPNIFIGAVTPMDKHGFFSLSLSTVYERDSLEKADVVIFEVNKNLP
RIFGDTSVHISQVDYVYESNEKVPELSPKEPSEKDFIIGQYIADLVDDGATIQLGIGGIPNAVAKSLMTKKDLGIHTEMI
TEGVVDLFEAGVVNNSKKTLHKNKIIGAFAFGSQRLYDFLDDNPCIEMKRCSYVNNPYTLAKNNKMTSINTSLSVDLTGQ
CASESLGFKQYSGTGGQTDTGIGAQMSPGGKSIIALYSTAKNGTISSIVPSHYMGAAITYSRNDVQYIVTEYGVANLRGK
SIKERVDSLIAIAHPDFRQELKKEAVKNRIW
>Mature_431_residues
MNYSEQLKNKIITVEKALSLVKSNDEIVTSLGPCEATLFMSRLHEIRDRVENVTVVSMLSALDYKYHTDPSMAGHFINES
TFFAGPARKAHSTGLVSYIPTHLRYAGINRLDYKTPNIFIGAVTPMDKHGFFSLSLSTVYERDSLEKADVVIFEVNKNLP
RIFGDTSVHISQVDYVYESNEKVPELSPKEPSEKDFIIGQYIADLVDDGATIQLGIGGIPNAVAKSLMTKKDLGIHTEMI
TEGVVDLFEAGVVNNSKKTLHKNKIIGAFAFGSQRLYDFLDDNPCIEMKRCSYVNNPYTLAKNNKMTSINTSLSVDLTGQ
CASESLGFKQYSGTGGQTDTGIGAQMSPGGKSIIALYSTAKNGTISSIVPSHYMGAAITYSRNDVQYIVTEYGVANLRGK
SIKERVDSLIAIAHPDFRQELKKEAVKNRIW

Specific function: Unknown

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=217, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI32563853, Length=312, Percent_Identity=44.2307692307692, Blast_Score=257, Evalue=7e-69,
Organism=Caenorhabditis elegans, GI17538151, Length=437, Percent_Identity=34.324942791762, Blast_Score=232, Evalue=3e-61,
Organism=Saccharomyces cerevisiae, GI6319456, Length=221, Percent_Identity=28.9592760180996, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI21358615, Length=423, Percent_Identity=39.0070921985816, Blast_Score=276, Evalue=3e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro [H]

EC number: NA

Molecular weight: Translated: 47544; Mature: 47544

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYSEQLKNKIITVEKALSLVKSNDEIVTSLGPCEATLFMSRLHEIRDRVENVTVVSMLS
CCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALDYKYHTDPSMAGHFINESTFFAGPARKAHSTGLVSYIPTHLRYAGINRLDYKTPNIFI
HHCCCCCCCHHHHHHHCCCCCEECCCCCHHCCCCHHHHHHHHHHHHCCCCCCCCCCCEEE
GAVTPMDKHGFFSLSLSTVYERDSLEKADVVIFEVNKNLPRIFGDTSVHISQVDYVYESN
EEECCCCCCCEEEEEHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCEEEEEEEEEEECCC
EKVPELSPKEPSEKDFIIGQYIADLVDDGATIQLGIGGIPNAVAKSLMTKKDLGIHTEMI
CCCCCCCCCCCCCCCEEHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHHH
TEGVVDLFEAGVVNNSKKTLHKNKIIGAFAFGSQRLYDFLDDNPCIEMKRCSYVNNPYTL
HHHHHHHHHHCCCCCCHHHHHHCCEEEEEECCCHHHHHHHCCCCCEEEHHCCCCCCCEEE
AKNNKMTSINTSLSVDLTGQCASESLGFKQYSGTGGQTDTGIGAQMSPGGKSIIALYSTA
ECCCCEEEECCEEEEEECCCCHHCCCCCEEECCCCCCCCCCCCCEECCCCCEEEEEEECC
KNGTISSIVPSHYMGAAITYSRNDVQYIVTEYGVANLRGKSIKERVDSLIAIAHPDFRQE
CCCCHHHHCCCHHCCEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHEEECCCHHHHH
LKKEAVKNRIW
HHHHHHHHCCC
>Mature Secondary Structure
MNYSEQLKNKIITVEKALSLVKSNDEIVTSLGPCEATLFMSRLHEIRDRVENVTVVSMLS
CCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALDYKYHTDPSMAGHFINESTFFAGPARKAHSTGLVSYIPTHLRYAGINRLDYKTPNIFI
HHCCCCCCCHHHHHHHCCCCCEECCCCCHHCCCCHHHHHHHHHHHHCCCCCCCCCCCEEE
GAVTPMDKHGFFSLSLSTVYERDSLEKADVVIFEVNKNLPRIFGDTSVHISQVDYVYESN
EEECCCCCCCEEEEEHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCEEEEEEEEEEECCC
EKVPELSPKEPSEKDFIIGQYIADLVDDGATIQLGIGGIPNAVAKSLMTKKDLGIHTEMI
CCCCCCCCCCCCCCCEEHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHHH
TEGVVDLFEAGVVNNSKKTLHKNKIIGAFAFGSQRLYDFLDDNPCIEMKRCSYVNNPYTL
HHHHHHHHHHCCCCCCHHHHHHCCEEEEEECCCHHHHHHHCCCCCEEEHHCCCCCCCEEE
AKNNKMTSINTSLSVDLTGQCASESLGFKQYSGTGGQTDTGIGAQMSPGGKSIIALYSTA
ECCCCEEEECCEEEEEECCCCHHCCCCCEEECCCCCCCCCCCCCEECCCCCEEEEEEECC
KNGTISSIVPSHYMGAAITYSRNDVQYIVTEYGVANLRGKSIKERVDSLIAIAHPDFRQE
CCCCHHHHCCCHHCCEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHEEECCCHHHHH
LKKEAVKNRIW
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]