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The map label for this gene is yfjD [C]

Identifier: 187932719

GI number: 187932719

Start: 3649611

End: 3650864

Strand: Reverse

Name: yfjD [C]

Synonym: CLL_A3454

Alternate gene names: 187932719

Gene position: 3650864-3649611 (Counterclockwise)

Preceding gene: 187932584

Following gene: 187934949

Centisome position: 96.07

GC content: 29.03

Gene sequence:

>1254_bases
TTGGACCCTAGTTATACGTGGGAGATAGTAATTTTAATAATATTACTTATGCTGTCAGCATTTTTTTCAATGTCAGAAAC
AGCATTAATGTCTGTAAACAAAATTAGACTAAGACACATGGTGGAAGAAGGCGTACCAGGAGCAAAATTAGTAGAAAAAC
TTACAGAAGATCCAAATAAGTTATTAGGAGCTATATTAATAGGTAATAACATAGCAAATATTGCAGCGTCAGGACTTGCT
ACTGTGCTTGCAACTAATATATTTGGTCCAACTGGAGTAGGAATAGCTACAGGAATTATGACTGTATTAGTATTAATTTT
CGGTGAAATAACGCCTAAATCTATTGCAAAGCAAAGATCAGATTCTGTTGCTTTAAAGGTTGGTAAACCTATAAAGTTAA
TAGTTACTATATTTAAACCTTTTGTATATATATTTACAGCAATATCATCATTTTTTATAAAAATTTTAGGTGCAGATCCT
AAAGCTACTGAACCATTTATTACTGAAGAAGAATTAAAAACAATGGTAGGTGTAAGCGAAGAAGAAGGTGTATTAGAAAA
TGTTGAAAAAGAAATGATATTCAATGTATTTGATTTCGCTGATCTTCAAGTAAAAGATGTAATGGTTCAAAGAGTTGATG
TTACTGCTTTAGATTCAGAATCAACTTATGATGATGTATTAAAGATTATAAAAGAAGAACAATTTTCTAGAATACCGATT
TATAATCAAACTATAGATGATGTTATTGGTATATTAAATGTTAAAGATTTATTAATGCTTGAAAATCCTAGAGAAAACTT
TAAAATGACGAAATACATAAGAGAACCGTTTTATACATTTGAATTTAAAAAGATTGTAGAATTATTTAAGGAAATGAAAA
AAGAACGAAATCACATCGCTGTTGTGTTAGATGAATATGGTGGTACTGTTGGAATAATTACCATAGAAGATTTAATAGAA
GAAATTGTTGGTGATATAGAAGATGAATATGATGATGCCAACACTAGCATTGAAGTGATTAAAGAAAATGAATATATAGT
AGATGGTAGTGTGAGACTTCATGATATTGGTGATTTAATAGGTACTGATATGGAATCAGATGAGTTTGATTCTGTTGGAG
GCCTTATAATTGGAGAACTTGGAAGAATGCCTGAAGAAAAAGAAGAAATTGAGTGCGATAATATGAAATTTATCGTAGAA
AATATAGATAAAAATAGAATTAAAAAAGTTAGAATATTTACAGATAACGAATAA

Upstream 100 bases:

>100_bases
TGATGTTTTTAATACTAATCCAATATATTACTTTTAATAATATTATGATATAATGTTGAGTAAAATATAATTATTAAATC
AATTAGGAGAGTGATTTTTT

Downstream 100 bases:

>100_bases
TCATAAAAGACTGCTGGCAAAAATAATCAGCAGTCTTTTTTATGGAGGTGAAAATATGAATTTTTTAGATATTGCTAAAG
AAGAAGCAAGGATAGCAATG

Product: membrane hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MDPSYTWEIVILIILLMLSAFFSMSETALMSVNKIRLRHMVEEGVPGAKLVEKLTEDPNKLLGAILIGNNIANIAASGLA
TVLATNIFGPTGVGIATGIMTVLVLIFGEITPKSIAKQRSDSVALKVGKPIKLIVTIFKPFVYIFTAISSFFIKILGADP
KATEPFITEEELKTMVGVSEEEGVLENVEKEMIFNVFDFADLQVKDVMVQRVDVTALDSESTYDDVLKIIKEEQFSRIPI
YNQTIDDVIGILNVKDLLMLENPRENFKMTKYIREPFYTFEFKKIVELFKEMKKERNHIAVVLDEYGGTVGIITIEDLIE
EIVGDIEDEYDDANTSIEVIKENEYIVDGSVRLHDIGDLIGTDMESDEFDSVGGLIIGELGRMPEEKEEIECDNMKFIVE
NIDKNRIKKVRIFTDNE

Sequences:

>Translated_417_residues
MDPSYTWEIVILIILLMLSAFFSMSETALMSVNKIRLRHMVEEGVPGAKLVEKLTEDPNKLLGAILIGNNIANIAASGLA
TVLATNIFGPTGVGIATGIMTVLVLIFGEITPKSIAKQRSDSVALKVGKPIKLIVTIFKPFVYIFTAISSFFIKILGADP
KATEPFITEEELKTMVGVSEEEGVLENVEKEMIFNVFDFADLQVKDVMVQRVDVTALDSESTYDDVLKIIKEEQFSRIPI
YNQTIDDVIGILNVKDLLMLENPRENFKMTKYIREPFYTFEFKKIVELFKEMKKERNHIAVVLDEYGGTVGIITIEDLIE
EIVGDIEDEYDDANTSIEVIKENEYIVDGSVRLHDIGDLIGTDMESDEFDSVGGLIIGELGRMPEEKEEIECDNMKFIVE
NIDKNRIKKVRIFTDNE
>Mature_417_residues
MDPSYTWEIVILIILLMLSAFFSMSETALMSVNKIRLRHMVEEGVPGAKLVEKLTEDPNKLLGAILIGNNIANIAASGLA
TVLATNIFGPTGVGIATGIMTVLVLIFGEITPKSIAKQRSDSVALKVGKPIKLIVTIFKPFVYIFTAISSFFIKILGADP
KATEPFITEEELKTMVGVSEEEGVLENVEKEMIFNVFDFADLQVKDVMVQRVDVTALDSESTYDDVLKIIKEEQFSRIPI
YNQTIDDVIGILNVKDLLMLENPRENFKMTKYIREPFYTFEFKKIVELFKEMKKERNHIAVVLDEYGGTVGIITIEDLIE
EIVGDIEDEYDDANTSIEVIKENEYIVDGSVRLHDIGDLIGTDMESDEFDSVGGLIIGELGRMPEEKEEIECDNMKFIVE
NIDKNRIKKVRIFTDNE

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=376, Percent_Identity=31.9148936170213, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI94681046, Length=347, Percent_Identity=25.6484149855908, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI40068055, Length=344, Percent_Identity=27.906976744186, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI40068053, Length=344, Percent_Identity=27.906976744186, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI40068051, Length=302, Percent_Identity=26.4900662251656, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI145693175, Length=400, Percent_Identity=29.25, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI1790664, Length=426, Percent_Identity=25.1173708920188, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1786879, Length=247, Percent_Identity=31.1740890688259, Blast_Score=131, Evalue=9e-32,
Organism=Escherichia coli, GI87082033, Length=228, Percent_Identity=24.5614035087719, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1788119, Length=234, Percent_Identity=23.0769230769231, Blast_Score=75, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17539402, Length=356, Percent_Identity=27.8089887640449, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6324512, Length=353, Percent_Identity=26.9121813031161, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 46904; Mature: 46904

Theoretical pI: Translated: 4.23; Mature: 4.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPSYTWEIVILIILLMLSAFFSMSETALMSVNKIRLRHMVEEGVPGAKLVEKLTEDPNK
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHH
LLGAILIGNNIANIAASGLATVLATNIFGPTGVGIATGIMTVLVLIFGEITPKSIAKQRS
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCC
DSVALKVGKPIKLIVTIFKPFVYIFTAISSFFIKILGADPKATEPFITEEELKTMVGVSE
CCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCC
EEGVLENVEKEMIFNVFDFADLQVKDVMVQRVDVTALDSESTYDDVLKIIKEEQFSRIPI
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCEEEECCCCCHHHHHHHHHHHHHCCCCC
YNQTIDDVIGILNVKDLLMLENPRENFKMTKYIREPFYTFEFKKIVELFKEMKKERNHIA
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEE
VVLDEYGGTVGIITIEDLIEEIVGDIEDEYDDANTSIEVIKENEYIVDGSVRLHDIGDLI
EEEECCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEECCEEEEEHHHHH
GTDMESDEFDSVGGLIIGELGRMPEEKEEIECDNMKFIVENIDKNRIKKVRIFTDNE
CCCCCCCCHHHHCCHHHHHHCCCCCCHHHCCCCCHHHHHHHCCCCCCEEEEEEECCC
>Mature Secondary Structure
MDPSYTWEIVILIILLMLSAFFSMSETALMSVNKIRLRHMVEEGVPGAKLVEKLTEDPNK
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHH
LLGAILIGNNIANIAASGLATVLATNIFGPTGVGIATGIMTVLVLIFGEITPKSIAKQRS
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCC
DSVALKVGKPIKLIVTIFKPFVYIFTAISSFFIKILGADPKATEPFITEEELKTMVGVSE
CCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCC
EEGVLENVEKEMIFNVFDFADLQVKDVMVQRVDVTALDSESTYDDVLKIIKEEQFSRIPI
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCEEEECCCCCHHHHHHHHHHHHHCCCCC
YNQTIDDVIGILNVKDLLMLENPRENFKMTKYIREPFYTFEFKKIVELFKEMKKERNHIA
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEE
VVLDEYGGTVGIITIEDLIEEIVGDIEDEYDDANTSIEVIKENEYIVDGSVRLHDIGDLI
EEEECCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEECCEEEEEHHHHH
GTDMESDEFDSVGGLIIGELGRMPEEKEEIECDNMKFIVENIDKNRIKKVRIFTDNE
CCCCCCCCHHHHCCHHHHHHCCCCCCHHHCCCCCHHHHHHHCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]