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The map label for this gene is ydeM [C]

Identifier: 187932645

GI number: 187932645

Start: 3076567

End: 3077922

Strand: Reverse

Name: ydeM [C]

Synonym: CLL_A2986

Alternate gene names: 187932645

Gene position: 3077922-3076567 (Counterclockwise)

Preceding gene: 187935604

Following gene: 187933860

Centisome position: 80.99

GC content: 28.76

Gene sequence:

>1356_bases
GTGTCTTTAATACACAAATTTAAACAAGGTGAAAACTTTTTTGTTTTAGATGTAAACACAGGTGCAGTACATGTAGTTGA
TGAATTAGTATATGATTTAGTTGATGACAATAAATTAAAATCTAAAGAAGAACTTATTAAGACTTTAAATAATAAATATG
AAGAAAATGTTATTTCAGAAGCATATGATGAAATACTTGAACTTATAGATAATGGAATTCTTTATTCTAAGGATCAATAT
GAAGATATAGCTCATAGCTCTATGGATGATAGAGATTACATAAAAGCTGTATGTTTAAATATAATTCACGGATGTAATTT
AAGATGTAAATATTGCTTTGCTGATGAAGGTGAATATCATGGACATAAAGGTGTAATGAGTCTTGACGTTGCTAAAAAAG
CAATTGATTATGTTGTTAAAAGAAGTGGTCCAAGAAAAAACATAGAAATAGATTTATTTGGTGGAGAACCAACTATGATA
ATGGACACTATAAAAGATATAATTAAATATGCAAGAGACAATGAAAAGAAGTGGAATAAGAACATAAGATTCACAATGAC
AACTAATGCTACTCTTTTAAATCCAGAAATGATGGATTTCATGGATAAAGAAATGGGTAATATAATATTATCATTAGATG
GAAGAAAATGTGTCAATGATAATGTTAGAATTAAAGCAGATGGAAGTGGATCATATGATGATATAATTCCTAATATAAAA
GAAATGATAAAAAGAAGAACTAAGGGGAAGACTTTCTACGTTAGAGGAACATTTACTAGAAATAATACAGATTTTTATGA
AGATGTTATGGCTATGATTAATGAAGGTTTTGATGAAATATCAATTGAACCAGTAGTATTACCAGATGAACATTCGCTTT
CATTAAGAGAAGAGGATTTAGAAACTATTTTCAAAAATTATGACAAGCTATATGAAGAAATGGCTAAGAGAAAGAGAGAA
GGAAAAGATGAATTTAACTTCTATCATTTCAATATAGATCTTCAAGGCGGACCTTGTGTCTATAAGAGAATTTCAGGGTG
TGGTGCAGGATTTGAATATGTAGCAATAACTCCTCAAGGAGATGTTTATCCATGTCATCAATTTGTTGGAAATGAAGAAT
TTAAATTAGGAACTATATATGATGATACTTATGATTCAGAATTAGGAAAGAAATTTAAAGAAGCACACATATATAATAAA
CCTAAATGTAGAGATTGTTGGGCTAAATTCTATTGTAGTGGTGGTTGCCAAGCTAACAACTTTAATTTCAATGGTGATAT
GAAGATTCCATATGAAATAGGATGTAAAATGCAAAAGAAGAGAATTGAATGTGCTATAGCACTTAAAGCTGAGTAA

Upstream 100 bases:

>100_bases
GCATTCCTAAGTTCAATTACTCAGTCCACTTTGCTTATGTATATATCAATATTCTACTAAAACATAGCCTATTTTATATA
TGAATTAGGAGGAAAAAACA

Downstream 100 bases:

>100_bases
TAAACTTAATGGGCTGCTATATAATAATTATCTTATTATATAGCAGCCTTATTTTTATATTATTTAATATAAAAATAAGG
CTAAATTGTAACTTTAATAG

Product: heme biosynthesis

Products: NA

Alternate protein names: AnSME; Cys-type sulfatase-activating enzyme [H]

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MSLIHKFKQGENFFVLDVNTGAVHVVDELVYDLVDDNKLKSKEELIKTLNNKYEENVISEAYDEILELIDNGILYSKDQY
EDIAHSSMDDRDYIKAVCLNIIHGCNLRCKYCFADEGEYHGHKGVMSLDVAKKAIDYVVKRSGPRKNIEIDLFGGEPTMI
MDTIKDIIKYARDNEKKWNKNIRFTMTTNATLLNPEMMDFMDKEMGNIILSLDGRKCVNDNVRIKADGSGSYDDIIPNIK
EMIKRRTKGKTFYVRGTFTRNNTDFYEDVMAMINEGFDEISIEPVVLPDEHSLSLREEDLETIFKNYDKLYEEMAKRKRE
GKDEFNFYHFNIDLQGGPCVYKRISGCGAGFEYVAITPQGDVYPCHQFVGNEEFKLGTIYDDTYDSELGKKFKEAHIYNK
PKCRDCWAKFYCSGGCQANNFNFNGDMKIPYEIGCKMQKKRIECAIALKAE

Sequences:

>Translated_451_residues
MSLIHKFKQGENFFVLDVNTGAVHVVDELVYDLVDDNKLKSKEELIKTLNNKYEENVISEAYDEILELIDNGILYSKDQY
EDIAHSSMDDRDYIKAVCLNIIHGCNLRCKYCFADEGEYHGHKGVMSLDVAKKAIDYVVKRSGPRKNIEIDLFGGEPTMI
MDTIKDIIKYARDNEKKWNKNIRFTMTTNATLLNPEMMDFMDKEMGNIILSLDGRKCVNDNVRIKADGSGSYDDIIPNIK
EMIKRRTKGKTFYVRGTFTRNNTDFYEDVMAMINEGFDEISIEPVVLPDEHSLSLREEDLETIFKNYDKLYEEMAKRKRE
GKDEFNFYHFNIDLQGGPCVYKRISGCGAGFEYVAITPQGDVYPCHQFVGNEEFKLGTIYDDTYDSELGKKFKEAHIYNK
PKCRDCWAKFYCSGGCQANNFNFNGDMKIPYEIGCKMQKKRIECAIALKAE
>Mature_450_residues
SLIHKFKQGENFFVLDVNTGAVHVVDELVYDLVDDNKLKSKEELIKTLNNKYEENVISEAYDEILELIDNGILYSKDQYE
DIAHSSMDDRDYIKAVCLNIIHGCNLRCKYCFADEGEYHGHKGVMSLDVAKKAIDYVVKRSGPRKNIEIDLFGGEPTMIM
DTIKDIIKYARDNEKKWNKNIRFTMTTNATLLNPEMMDFMDKEMGNIILSLDGRKCVNDNVRIKADGSGSYDDIIPNIKE
MIKRRTKGKTFYVRGTFTRNNTDFYEDVMAMINEGFDEISIEPVVLPDEHSLSLREEDLETIFKNYDKLYEEMAKRKREG
KDEFNFYHFNIDLQGGPCVYKRISGCGAGFEYVAITPQGDVYPCHQFVGNEEFKLGTIYDDTYDSELGKKFKEAHIYNKP
KCRDCWAKFYCSGGCQANNFNFNGDMKIPYEIGCKMQKKRIECAIALKAE

Specific function: Involved in 'Cys-type' sulfatase maturation under anaerobic conditions. Catalyzes the post-translational modification of cysteine into 3-oxoalanine (also known as C(alpha)-formylglycine (FGly)), by a free radical chemical mechanism initiated via the reduc

COG id: COG0641

COG function: function code R; Arylsulfatase regulator (Fe-S oxidoreductase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 52076; Mature: 51945

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS01305 MOAA_NIFB_PQQE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLIHKFKQGENFFVLDVNTGAVHVVDELVYDLVDDNKLKSKEELIKTLNNKYEENVISE
CCHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
AYDEILELIDNGILYSKDQYEDIAHSSMDDRDYIKAVCLNIIHGCNLRCKYCFADEGEYH
HHHHHHHHHHCCCEECCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
GHKGVMSLDVAKKAIDYVVKRSGPRKNIEIDLFGGEPTMIMDTIKDIIKYARDNEKKWNK
CCCCCEEHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCHHHCC
NIRFTMTTNATLLNPEMMDFMDKEMGNIILSLDGRKCVNDNVRIKADGSGSYDDIIPNIK
CEEEEEECCCEEECHHHHHHHHHHHCCEEEEECCCEECCCCEEEEECCCCCHHHHHHHHH
EMIKRRTKGKTFYVRGTFTRNNTDFYEDVMAMINEGFDEISIEPVVLPDEHSLSLREEDL
HHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCHHHH
ETIFKNYDKLYEEMAKRKREGKDEFNFYHFNIDLQGGPCVYKRISGCGAGFEYVAITPQG
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCHHHHHHCCCCCCEEEEECCCC
DVYPCHQFVGNEEFKLGTIYDDTYDSELGKKFKEAHIYNKPKCRDCWAKFYCSGGCQANN
CCCHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCC
FNFNGDMKIPYEIGCKMQKKRIECAIALKAE
CCCCCCEECCHHHCCCCCCCEEEEEEEEECC
>Mature Secondary Structure 
SLIHKFKQGENFFVLDVNTGAVHVVDELVYDLVDDNKLKSKEELIKTLNNKYEENVISE
CHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
AYDEILELIDNGILYSKDQYEDIAHSSMDDRDYIKAVCLNIIHGCNLRCKYCFADEGEYH
HHHHHHHHHHCCCEECCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
GHKGVMSLDVAKKAIDYVVKRSGPRKNIEIDLFGGEPTMIMDTIKDIIKYARDNEKKWNK
CCCCCEEHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCHHHCC
NIRFTMTTNATLLNPEMMDFMDKEMGNIILSLDGRKCVNDNVRIKADGSGSYDDIIPNIK
CEEEEEECCCEEECHHHHHHHHHHHCCEEEEECCCEECCCCEEEEECCCCCHHHHHHHHH
EMIKRRTKGKTFYVRGTFTRNNTDFYEDVMAMINEGFDEISIEPVVLPDEHSLSLREEDL
HHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCHHHH
ETIFKNYDKLYEEMAKRKREGKDEFNFYHFNIDLQGGPCVYKRISGCGAGFEYVAITPQG
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCHHHHHHCCCCCCEEEEECCCC
DVYPCHQFVGNEEFKLGTIYDDTYDSELGKKFKEAHIYNKPKCRDCWAKFYCSGGCQANN
CCCHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCC
FNFNGDMKIPYEIGCKMQKKRIECAIALKAE
CCCCCCEECCHHHCCCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA