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The map label for this gene is yycG [H]

Identifier: 187932591

GI number: 187932591

Start: 1029392

End: 1031560

Strand: Reverse

Name: yycG [H]

Synonym: CLL_A1016

Alternate gene names: 187932591

Gene position: 1031560-1029392 (Counterclockwise)

Preceding gene: 187934167

Following gene: 187933631

Centisome position: 27.14

GC content: 23.7

Gene sequence:

>2169_bases
ATGAATTCCCACGAAAATTCTATAAAAAGAAAATATACAATTGAAGATTTAGAAAATATACTAGATTCTATACCTAATTG
TATATGGACAAAGGATAAAAATGGTGAATATACTTATGTAAATAAAACTTTTTCTGAAAATATGAATCTTTCAAAAGATG
AAATTATCGGAAAAACTGATTTTGATTTTGGAAATACTAAACTTGCTAAAATTTTTGATAAAGATGATAAAAAAGTATTA
TCAAGAAATATTCCAACATTAAGTGAAAACAAAATAAAGATTCAAGGAAAAAAGCGATGGTTTGAAATTTATAAAACCCC
ATTAAAAAGAAAAGATAATAGTTTTCCTTGGATTATGGCTATAGCAAGAGAGACTACTTTTGATAAAACATTAGATGAAG
ATTTGCAAAATCTTTTTAATGCCAATAAATCATATGAATTAAACAATGATATTATACTTCCTGCAATTAACACCAAAGAT
ATTATTGACAATAAGAATACTAGTAATAAATATTTATATAAATTACAAAAAATTATTGACAGTTTATCTAGTAGATTAAA
AACTGAGGGCGTTAGCTTATTTTTGTATAATAAATCTGATAAATGTTTAAATTTATATTTAAATGCAGGCAAAAGTAATA
TTAATGTTAAAGATATAATTCCACTAACTAATAATGATATTATCAATTTGAATAAAAATATATATAATAATGTTTTTGAA
GTTAATAAAAATAGTATATTCTGCACTTATCAGAAAAAATATCAAAAAAATAATTCTATACATTGTATAAGATCTTGTAG
TATAAAATATTCCAATGATTTAATTGGTGTATTAAATATTTATTATCCAACAAACTATACCCCTAAATTTTCACAAGAAG
ATTTTATAAAATCAACCTGTAATAAACTGGGAATATTAATAAAAAATCATATTCTTTCCTGTCAATTAAAAAATGAATTT
CAAAAACGTCTTTATATAGAAAAAGAATTAGAATTATTTTTAGACACGGCAACTGATTCATGTGCTTTAGTAGATTTTGA
CGGAACCTTTCTTAAAATAAGCAACAATTTTACTAATACGCTTGGTTGGAATGAAGATGAACTTTTAGATAAAAAATTTC
AAGATTTAATTTATCCAGATGATATTGAAAAATCTAATAATTTTAGAAAAAACGTACGTGATTCAGGTAAATTTAAAGGT
TCTGGACTTATTCATAGATACCTTTGTAAAAATGGTCAATATAAAACACTAGAGTGGAATTGGAATTTAATTCAAGATGA
AAATCATATTATATTAACTGGTAAAGATATAACTGAAGAAAAAAAATTAAAAGAAGAAAAAAAGCATTTAGAGGAAACAG
TAGCATTAGAGACTTTAAAAACAACTTTTTTTGCTAATGTCTCTCATGAATTTAGAACTCCACTTAATATAATACTTACA
GCAATTCAATTAATCTCTATAAAATTATCTAATTGCCCTTGTTCTGAAGAAAAAGAAAAAATTTTTCAATATATTAGGGG
AATAAAACAAAACTCTTATAGATTATTAAAGTTAGTAAATAACTTATTGGATTTAACAAAAATAGATGGTGGGTATTACG
AGTTAAAGTCAATAAAATGTAATATAGTTAATTTAATTGAAGAAATAGTTTTATCTGTTGCAGATCATATTGGTAGTAAA
AAAAGAGAGATAATATTTGACACAACAGAAGAAGAAATTTTAACATCATGTGATCCAGAAAAAATTGAAACAATATTATT
AAACTTATTATCAAATGCAGTAAAATTCACCAAAGAAAATGATTCAATCGAAGTAAATTTAAATGTAGATTCTTATTATA
AAAATGTAGTTGTATCTGTAAAGGATAGTGGATGTAAAATTGACAAAGAAGACGCTAAAATAATTTTTAATAGATTTACT
CAACTAGATGCGTTATTAAATAGACGTTGTGAGGGTAGTGGAATTGGACTTGCTTTAGTAAAGTCTTTAGTAGATTTACA
TGGTGGTGATATTTGGGTAAATACTCTATTTGAAGATGGAGCTGAAATCATCTTTACTATTCCAATTAAAGAACTTGAAT
CTAAAAAAATTTCAGAATTTCATACTAAAACATTAAATGCCAACATCGAACGTTACAATGTTGAATTTTCTGATATATAT
AATCTTTAA

Upstream 100 bases:

>100_bases
AATATATTACATTAATTCTATTATATTGTTGATATACACTTAATTTCAGCCTATAATAGGTTTAAATAATAATTTTTTTA
CTTTCAGGGAGGTGCATCAT

Downstream 100 bases:

>100_bases
TTTAAATCCCTTATATATGATTTATTAAAAAACACTACTAGAATGTAAAATTTCTAGTAATGTTTTTATAATATTATTAA
ACCAAATTTATTAACATTAT

Product: sensory transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 722; Mature: 722

Protein sequence:

>722_residues
MNSHENSIKRKYTIEDLENILDSIPNCIWTKDKNGEYTYVNKTFSENMNLSKDEIIGKTDFDFGNTKLAKIFDKDDKKVL
SRNIPTLSENKIKIQGKKRWFEIYKTPLKRKDNSFPWIMAIARETTFDKTLDEDLQNLFNANKSYELNNDIILPAINTKD
IIDNKNTSNKYLYKLQKIIDSLSSRLKTEGVSLFLYNKSDKCLNLYLNAGKSNINVKDIIPLTNNDIINLNKNIYNNVFE
VNKNSIFCTYQKKYQKNNSIHCIRSCSIKYSNDLIGVLNIYYPTNYTPKFSQEDFIKSTCNKLGILIKNHILSCQLKNEF
QKRLYIEKELELFLDTATDSCALVDFDGTFLKISNNFTNTLGWNEDELLDKKFQDLIYPDDIEKSNNFRKNVRDSGKFKG
SGLIHRYLCKNGQYKTLEWNWNLIQDENHIILTGKDITEEKKLKEEKKHLEETVALETLKTTFFANVSHEFRTPLNIILT
AIQLISIKLSNCPCSEEKEKIFQYIRGIKQNSYRLLKLVNNLLDLTKIDGGYYELKSIKCNIVNLIEEIVLSVADHIGSK
KREIIFDTTEEEILTSCDPEKIETILLNLLSNAVKFTKENDSIEVNLNVDSYYKNVVVSVKDSGCKIDKEDAKIIFNRFT
QLDALLNRRCEGSGIGLALVKSLVDLHGGDIWVNTLFEDGAEIIFTIPIKELESKKISEFHTKTLNANIERYNVEFSDIY
NL

Sequences:

>Translated_722_residues
MNSHENSIKRKYTIEDLENILDSIPNCIWTKDKNGEYTYVNKTFSENMNLSKDEIIGKTDFDFGNTKLAKIFDKDDKKVL
SRNIPTLSENKIKIQGKKRWFEIYKTPLKRKDNSFPWIMAIARETTFDKTLDEDLQNLFNANKSYELNNDIILPAINTKD
IIDNKNTSNKYLYKLQKIIDSLSSRLKTEGVSLFLYNKSDKCLNLYLNAGKSNINVKDIIPLTNNDIINLNKNIYNNVFE
VNKNSIFCTYQKKYQKNNSIHCIRSCSIKYSNDLIGVLNIYYPTNYTPKFSQEDFIKSTCNKLGILIKNHILSCQLKNEF
QKRLYIEKELELFLDTATDSCALVDFDGTFLKISNNFTNTLGWNEDELLDKKFQDLIYPDDIEKSNNFRKNVRDSGKFKG
SGLIHRYLCKNGQYKTLEWNWNLIQDENHIILTGKDITEEKKLKEEKKHLEETVALETLKTTFFANVSHEFRTPLNIILT
AIQLISIKLSNCPCSEEKEKIFQYIRGIKQNSYRLLKLVNNLLDLTKIDGGYYELKSIKCNIVNLIEEIVLSVADHIGSK
KREIIFDTTEEEILTSCDPEKIETILLNLLSNAVKFTKENDSIEVNLNVDSYYKNVVVSVKDSGCKIDKEDAKIIFNRFT
QLDALLNRRCEGSGIGLALVKSLVDLHGGDIWVNTLFEDGAEIIFTIPIKELESKKISEFHTKTLNANIERYNVEFSDIY
NL
>Mature_722_residues
MNSHENSIKRKYTIEDLENILDSIPNCIWTKDKNGEYTYVNKTFSENMNLSKDEIIGKTDFDFGNTKLAKIFDKDDKKVL
SRNIPTLSENKIKIQGKKRWFEIYKTPLKRKDNSFPWIMAIARETTFDKTLDEDLQNLFNANKSYELNNDIILPAINTKD
IIDNKNTSNKYLYKLQKIIDSLSSRLKTEGVSLFLYNKSDKCLNLYLNAGKSNINVKDIIPLTNNDIINLNKNIYNNVFE
VNKNSIFCTYQKKYQKNNSIHCIRSCSIKYSNDLIGVLNIYYPTNYTPKFSQEDFIKSTCNKLGILIKNHILSCQLKNEF
QKRLYIEKELELFLDTATDSCALVDFDGTFLKISNNFTNTLGWNEDELLDKKFQDLIYPDDIEKSNNFRKNVRDSGKFKG
SGLIHRYLCKNGQYKTLEWNWNLIQDENHIILTGKDITEEKKLKEEKKHLEETVALETLKTTFFANVSHEFRTPLNIILT
AIQLISIKLSNCPCSEEKEKIFQYIRGIKQNSYRLLKLVNNLLDLTKIDGGYYELKSIKCNIVNLIEEIVLSVADHIGSK
KREIIFDTTEEEILTSCDPEKIETILLNLLSNAVKFTKENDSIEVNLNVDSYYKNVVVSVKDSGCKIDKEDAKIIFNRFT
QLDALLNRRCEGSGIGLALVKSLVDLHGGDIWVNTLFEDGAEIIFTIPIKELESKKISEFHTKTLNANIERYNVEFSDIY
NL

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=278, Percent_Identity=30.5755395683453, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI1789149, Length=236, Percent_Identity=30.5084745762712, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1786912, Length=248, Percent_Identity=27.8225806451613, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI145693157, Length=267, Percent_Identity=25.0936329588015, Blast_Score=97, Evalue=5e-21,
Organism=Escherichia coli, GI1786600, Length=259, Percent_Identity=25.8687258687259, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1786783, Length=240, Percent_Identity=27.9166666666667, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI87081816, Length=258, Percent_Identity=26.7441860465116, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI48994928, Length=263, Percent_Identity=29.6577946768061, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1790436, Length=247, Percent_Identity=27.1255060728745, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI1788549, Length=365, Percent_Identity=23.5616438356164, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1788393, Length=254, Percent_Identity=22.4409448818898, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1790346, Length=243, Percent_Identity=26.7489711934156, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87082128, Length=242, Percent_Identity=25.2066115702479, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1790861, Length=217, Percent_Identity=27.6497695852535, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1789403, Length=235, Percent_Identity=24.2553191489362, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 83641; Mature: 83641

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSHENSIKRKYTIEDLENILDSIPNCIWTKDKNGEYTYVNKTFSENMNLSKDEIIGKTD
CCCCCCHHHHEEEHHHHHHHHHHCCCEEEECCCCCCEEEEECHHHCCCCCCHHHCCCCCC
FDFGNTKLAKIFDKDDKKVLSRNIPTLSENKIKIQGKKRWFEIYKTPLKRKDNSFPWIMA
CCCCCCCEEEECCCCHHHHHHCCCCCCCCCEEEEECHHHHHHHHHCHHHCCCCCCCEEEE
IARETTFDKTLDEDLQNLFNANKSYELNNDIILPAINTKDIIDNKNTSNKYLYKLQKIID
EEHHCCHHHHHHHHHHHHHCCCCCEECCCCEEEEECCCHHHCCCCCCCHHHHHHHHHHHH
SLSSRLKTEGVSLFLYNKSDKCLNLYLNAGKSNINVKDIIPLTNNDIINLNKNIYNNVFE
HHHHHHHHCCEEEEEECCCCCEEEEEEECCCCCCCEEEEEECCCCCEEEECHHHHCCCEE
VNKNSIFCTYQKKYQKNNSIHCIRSCSIKYSNDLIGVLNIYYPTNYTPKFSQEDFIKSTC
ECCCCEEEEEEHHHCCCCCEEEEEECCEEECCCEEEEEEEEECCCCCCCCCHHHHHHHHH
NKLGILIKNHILSCQLKNEFQKRLYIEKELELFLDTATDSCALVDFDGTFLKISNNFTNT
HHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHEEECCCCCEEEEECCCEEEEEECCCCCC
LGWNEDELLDKKFQDLIYPDDIEKSNNFRKNVRDSGKFKGSGLIHRYLCKNGQYKTLEWN
CCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHCCCCEEEEEEE
WNLIQDENHIILTGKDITEEKKLKEEKKHLEETVALETLKTTFFANVSHEFRTPLNIILT
CEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHH
AIQLISIKLSNCPCSEEKEKIFQYIRGIKQNSYRLLKLVNNLLDLTKIDGGYYELKSIKC
HHHHHHEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCH
NIVNLIEEIVLSVADHIGSKKREIIFDTTEEEILTSCDPEKIETILLNLLSNAVKFTKEN
HHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC
DSIEVNLNVDSYYKNVVVSVKDSGCKIDKEDAKIIFNRFTQLDALLNRRCEGSGIGLALV
CCEEEEEEHHHEECEEEEEEECCCCEECCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
KSLVDLHGGDIWVNTLFEDGAEIIFTIPIKELESKKISEFHTKTLNANIERYNVEFSDIY
HHHHHHCCCCEEEEEECCCCCEEEEEEEHHHHCCHHHHHHHHHHHCCCEEEEECCHHHHC
NL
CC
>Mature Secondary Structure
MNSHENSIKRKYTIEDLENILDSIPNCIWTKDKNGEYTYVNKTFSENMNLSKDEIIGKTD
CCCCCCHHHHEEEHHHHHHHHHHCCCEEEECCCCCCEEEEECHHHCCCCCCHHHCCCCCC
FDFGNTKLAKIFDKDDKKVLSRNIPTLSENKIKIQGKKRWFEIYKTPLKRKDNSFPWIMA
CCCCCCCEEEECCCCHHHHHHCCCCCCCCCEEEEECHHHHHHHHHCHHHCCCCCCCEEEE
IARETTFDKTLDEDLQNLFNANKSYELNNDIILPAINTKDIIDNKNTSNKYLYKLQKIID
EEHHCCHHHHHHHHHHHHHCCCCCEECCCCEEEEECCCHHHCCCCCCCHHHHHHHHHHHH
SLSSRLKTEGVSLFLYNKSDKCLNLYLNAGKSNINVKDIIPLTNNDIINLNKNIYNNVFE
HHHHHHHHCCEEEEEECCCCCEEEEEEECCCCCCCEEEEEECCCCCEEEECHHHHCCCEE
VNKNSIFCTYQKKYQKNNSIHCIRSCSIKYSNDLIGVLNIYYPTNYTPKFSQEDFIKSTC
ECCCCEEEEEEHHHCCCCCEEEEEECCEEECCCEEEEEEEEECCCCCCCCCHHHHHHHHH
NKLGILIKNHILSCQLKNEFQKRLYIEKELELFLDTATDSCALVDFDGTFLKISNNFTNT
HHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHEEECCCCCEEEEECCCEEEEEECCCCCC
LGWNEDELLDKKFQDLIYPDDIEKSNNFRKNVRDSGKFKGSGLIHRYLCKNGQYKTLEWN
CCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHCCCCEEEEEEE
WNLIQDENHIILTGKDITEEKKLKEEKKHLEETVALETLKTTFFANVSHEFRTPLNIILT
CEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHH
AIQLISIKLSNCPCSEEKEKIFQYIRGIKQNSYRLLKLVNNLLDLTKIDGGYYELKSIKC
HHHHHHEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCH
NIVNLIEEIVLSVADHIGSKKREIIFDTTEEEILTSCDPEKIETILLNLLSNAVKFTKEN
HHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC
DSIEVNLNVDSYYKNVVVSVKDSGCKIDKEDAKIIFNRFTQLDALLNRRCEGSGIGLALV
CCEEEEEEHHHEECEEEEEEECCCCEECCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
KSLVDLHGGDIWVNTLFEDGAEIIFTIPIKELESKKISEFHTKTLNANIERYNVEFSDIY
HHHHHHCCCCEEEEEECCCCCEEEEEEEHHHHCCHHHHHHHHHHHCCCEEEEECCHHHHC
NL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]