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The map label for this gene is dhaD [H]

Identifier: 187934167

GI number: 187934167

Start: 1032828

End: 1033913

Strand: Reverse

Name: dhaD [H]

Synonym: CLL_A1018

Alternate gene names: 187934167

Gene position: 1033913-1032828 (Counterclockwise)

Preceding gene: 187934926

Following gene: 187932591

Centisome position: 27.21

GC content: 31.4

Gene sequence:

>1086_bases
ATGGCAAATATTATCATTTCACCAGGTAAATATGTTCAAGGAAATGGCGAACTTGAAAATATAGCAACACATACTAGAAA
TTTAGGGGATAACTTTTTTGTAATCATTAGTACCTCTGGAATGAAAAGAGTATCTAACACTATAAAAAATAGTTTTTCTA
ATAACGATGAAAATTTAACATTTGAAATATTTAATGGAGAATGCTCAGAAATTGAAATTATGAGATTACAAAAATCATTT
AAAGAGAATAATTGTAATGTTGTTATAGGAGTAGGTGGAGGTAAAATTTTAGACACTGCTAAAGCTGTAGCATATTATGA
AGATGCTCCTGTAGTAATAGCTCCAACAATTGCTTCTACAGATGCTCCTTGTAGTGCATTATCTGTTATTTATACAGATA
ATGGTATTTTCGATAAATACTTAATATTAAAGAAAAATCCTGATATTGTCTTACTAGATACAAAAATTATAGTTAATGCT
CCATCAAGATTATTAATTTCTGGTATGGGAGATGCACTAGCAACTTATTTTGAAGCAAGAGCTTGTAGAAGAGCAAATAG
CTTGAATTTAGCTGGAGGACATATAACATTAGCTGCTGAAACATTAGCCCACGCATGTTACAAAACATTATTATCAGAAG
GATATAAAGCAAAACTTGCTGTCAATAACAATGTTGTTACTAAAGCAGTTGAGAACATAGTAGAAGCAACCACCTTATTA
AGTTGTTTAGGATTTGAGAGTGGCGGATTAGCTGCTGCACATGCCATATACAATGGCTTTACAATTCTAAAGGAATGTCA
TGATTTATATCATGGAGAAAAAGTTGCATTTGGTACCATTACACAACTAGTACTAGAAAATGCACCTATTGAAGAAATCA
GAGAAGTTATAACTTTCTGCAGATTAATTGGACTTCCAACTAATCTATCTGAAATGGGAATTAAAAACATCGATAAAGAT
GATATAATGAGAGTAGCTGAAGCTTGTTGCGCTGAAGGTGAAACTATTCACAATATGCCATTTGACATTACAGCATATGA
TGTATATGCTGCTATTTTAACAGCTAACAAATTAGGAAAATCTTAA

Upstream 100 bases:

>100_bases
TAATTTTCTTGTTTATTAAAATTTGTAACATAAACCATATTTTGAATTATATATGCTATACTAGATTTGTATTATTTTAT
ATATTTTAGGAGGAATAATT

Downstream 100 bases:

>100_bases
TATTTACTTTTCAATATTATTTAAAATAATAAAATTCAAAAAGTGTACAATCTTTATTATTAATTATTGTACACTTTTTT
GAATTTTATTAATATTTCTT

Product: glycerol dehydrogenase

Products: NA

Alternate protein names: GDH; GLDH [H]

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MANIIISPGKYVQGNGELENIATHTRNLGDNFFVIISTSGMKRVSNTIKNSFSNNDENLTFEIFNGECSEIEIMRLQKSF
KENNCNVVIGVGGGKILDTAKAVAYYEDAPVVIAPTIASTDAPCSALSVIYTDNGIFDKYLILKKNPDIVLLDTKIIVNA
PSRLLISGMGDALATYFEARACRRANSLNLAGGHITLAAETLAHACYKTLLSEGYKAKLAVNNNVVTKAVENIVEATTLL
SCLGFESGGLAAAHAIYNGFTILKECHDLYHGEKVAFGTITQLVLENAPIEEIREVITFCRLIGLPTNLSEMGIKNIDKD
DIMRVAEACCAEGETIHNMPFDITAYDVYAAILTANKLGKS

Sequences:

>Translated_361_residues
MANIIISPGKYVQGNGELENIATHTRNLGDNFFVIISTSGMKRVSNTIKNSFSNNDENLTFEIFNGECSEIEIMRLQKSF
KENNCNVVIGVGGGKILDTAKAVAYYEDAPVVIAPTIASTDAPCSALSVIYTDNGIFDKYLILKKNPDIVLLDTKIIVNA
PSRLLISGMGDALATYFEARACRRANSLNLAGGHITLAAETLAHACYKTLLSEGYKAKLAVNNNVVTKAVENIVEATTLL
SCLGFESGGLAAAHAIYNGFTILKECHDLYHGEKVAFGTITQLVLENAPIEEIREVITFCRLIGLPTNLSEMGIKNIDKD
DIMRVAEACCAEGETIHNMPFDITAYDVYAAILTANKLGKS
>Mature_360_residues
ANIIISPGKYVQGNGELENIATHTRNLGDNFFVIISTSGMKRVSNTIKNSFSNNDENLTFEIFNGECSEIEIMRLQKSFK
ENNCNVVIGVGGGKILDTAKAVAYYEDAPVVIAPTIASTDAPCSALSVIYTDNGIFDKYLILKKNPDIVLLDTKIIVNAP
SRLLISGMGDALATYFEARACRRANSLNLAGGHITLAAETLAHACYKTLLSEGYKAKLAVNNNVVTKAVENIVEATTLLS
CLGFESGGLAAAHAIYNGFTILKECHDLYHGEKVAFGTITQLVLENAPIEEIREVITFCRLIGLPTNLSEMGIKNIDKDD
IMRVAEACCAEGETIHNMPFDITAYDVYAAILTANKLGKS

Specific function: Catalyzes the NAD-dependent oxidation of glycerol to dihydroxyacetone (glycerone). Allows microorganisms to utilize glycerol as a source of carbon under anaerobic conditions. Exhibits a rather broad substrate specificity since it can also oxidize 1,2-prop

COG id: COG0371

COG function: function code C; Glycerol dehydrogenase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI87082352, Length=362, Percent_Identity=53.3149171270718, Blast_Score=384, Evalue=1e-108,
Organism=Escherichia coli, GI1786815, Length=295, Percent_Identity=32.5423728813559, Blast_Score=130, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211
- InterPro:   IPR016205 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.6 [H]

Molecular weight: Translated: 39045; Mature: 38914

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2 ; PS00687 ALDEHYDE_DEHYDR_GLU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANIIISPGKYVQGNGELENIATHTRNLGDNFFVIISTSGMKRVSNTIKNSFSNNDENLT
CCCEEECCCCEEECCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCEEE
FEIFNGECSEIEIMRLQKSFKENNCNVVIGVGGGKILDTAKAVAYYEDAPVVIAPTIAST
EEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHEEECCCCEEEEECCCCC
DAPCSALSVIYTDNGIFDKYLILKKNPDIVLLDTKIIVNAPSRLLISGMGDALATYFEAR
CCCCCEEEEEEECCCCEEEEEEEECCCCEEEEEEEEEEECCCHHEEECCHHHHHHHHHHH
ACRRANSLNLAGGHITLAAETLAHACYKTLLSEGYKAKLAVNNNVVTKAVENIVEATTLL
HHHCCCCCEECCCEEEEHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHH
SCLGFESGGLAAAHAIYNGFTILKECHDLYHGEKVAFGTITQLVLENAPIEEIREVITFC
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHCCCCHHHHHHHHHHH
RLIGLPTNLSEMGIKNIDKDDIMRVAEACCAEGETIHNMPFDITAYDVYAAILTANKLGK
HHHCCCCCHHHHCCCCCCHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHCCC
S
C
>Mature Secondary Structure 
ANIIISPGKYVQGNGELENIATHTRNLGDNFFVIISTSGMKRVSNTIKNSFSNNDENLT
CCEEECCCCEEECCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCEEE
FEIFNGECSEIEIMRLQKSFKENNCNVVIGVGGGKILDTAKAVAYYEDAPVVIAPTIAST
EEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHEEECCCCEEEEECCCCC
DAPCSALSVIYTDNGIFDKYLILKKNPDIVLLDTKIIVNAPSRLLISGMGDALATYFEAR
CCCCCEEEEEEECCCCEEEEEEEECCCCEEEEEEEEEEECCCHHEEECCHHHHHHHHHHH
ACRRANSLNLAGGHITLAAETLAHACYKTLLSEGYKAKLAVNNNVVTKAVENIVEATTLL
HHHCCCCCEECCCEEEEHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHH
SCLGFESGGLAAAHAIYNGFTILKECHDLYHGEKVAFGTITQLVLENAPIEEIREVITFC
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHCCCCHHHHHHHHHHH
RLIGLPTNLSEMGIKNIDKDDIMRVAEACCAEGETIHNMPFDITAYDVYAAILTANKLGK
HHHCCCCCHHHHCCCCCCHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHCCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA