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The map label for this gene is sigW [H]

Identifier: 187932438

GI number: 187932438

Start: 3745097

End: 3745669

Strand: Reverse

Name: sigW [H]

Synonym: CLL_A3537

Alternate gene names: 187932438

Gene position: 3745669-3745097 (Counterclockwise)

Preceding gene: 187932989

Following gene: 187933193

Centisome position: 98.56

GC content: 27.75

Gene sequence:

>573_bases
GTGAGTGAAAAGGAACTTGTTCAAAAAATCCAGTCTGGTGATATGAACGCTTTAGGCGAAATATTTGAGATATACAAAAA
CCAAGCATTAAAATATGCATATTTGATTACAGGAAATAAATTTACTAGTGAAGATATTGTACAAGAAGCATTTATAAAAT
GTTATTTAAGTGCTAAGAGTCTAAAAAATATAGAACAATTTAAACCATGGTTTTTTAAAATTCTAACAAGACTTGCTTGG
AAACATGTAGGTAAAGAGAAAAAAGCTTTGCCTTTTGAAAATATTTTTGAAAAAGCAAATGATGAAAGTATTGATAAATC
AATTGATATATATATAAGAGACCAAGAGGCAGAAACACTTCATGCTGAAATTGAGCATTTAGATTTAAAGCAAAAAACAG
TGATAATACTTTTTTATTTTAACGGATTAACTATAAAGGAAATTGCAAAAATTATGGGATGCTTTGAGGGAACGGTAAAA
TCAAGGCTTTATACTGCAAGAAAAAAATTAAAAGAAACCTTATCAAAGGATAAAAAGTGTGAAATATCAAAAGCAAAGGA
GTGTGAAGTTTAA

Upstream 100 bases:

>100_bases
TATTTTAAAAAATCTTTTATTATAAATGAACCATTTTTAAAGTTAAAGTCTCTTATATATAGATGCATCTAGAGAGGCCT
TTAAGGAAGGAGATATAAAA

Downstream 100 bases:

>100_bases
TGGACAGAAAATTAAATGAAAACATAGATGAAAAAATTATAGATTGTTTAAATAAAAAATCTGATGGAATTTCAGCTCCA
GAAAATATGTTTTTTAAAAT

Product: RNA polymerase ECF-type sigma factor

Products: NA

Alternate protein names: Sigma-W factor [H]

Number of amino acids: Translated: 190; Mature: 189

Protein sequence:

>190_residues
MSEKELVQKIQSGDMNALGEIFEIYKNQALKYAYLITGNKFTSEDIVQEAFIKCYLSAKSLKNIEQFKPWFFKILTRLAW
KHVGKEKKALPFENIFEKANDESIDKSIDIYIRDQEAETLHAEIEHLDLKQKTVIILFYFNGLTIKEIAKIMGCFEGTVK
SRLYTARKKLKETLSKDKKCEISKAKECEV

Sequences:

>Translated_190_residues
MSEKELVQKIQSGDMNALGEIFEIYKNQALKYAYLITGNKFTSEDIVQEAFIKCYLSAKSLKNIEQFKPWFFKILTRLAW
KHVGKEKKALPFENIFEKANDESIDKSIDIYIRDQEAETLHAEIEHLDLKQKTVIILFYFNGLTIKEIAKIMGCFEGTVK
SRLYTARKKLKETLSKDKKCEISKAKECEV
>Mature_189_residues
SEKELVQKIQSGDMNALGEIFEIYKNQALKYAYLITGNKFTSEDIVQEAFIKCYLSAKSLKNIEQFKPWFFKILTRLAWK
HVGKEKKALPFENIFEKANDESIDKSIDIYIRDQEAETLHAEIEHLDLKQKTVIILFYFNGLTIKEIAKIMGCFEGTVKS
RLYTARKKLKETLSKDKKCEISKAKECEV

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-W controls genes involved in transport processes and detoxification [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=180, Percent_Identity=27.7777777777778, Blast_Score=75, Evalue=3e-15,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014294
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 22119; Mature: 21988

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKELVQKIQSGDMNALGEIFEIYKNQALKYAYLITGNKFTSEDIVQEAFIKCYLSAKS
CCHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHH
LKNIEQFKPWFFKILTRLAWKHVGKEKKALPFENIFEKANDESIDKSIDIYIRDQEAETL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCEEEEEECCCHHHH
HAEIEHLDLKQKTVIILFYFNGLTIKEIAKIMGCFEGTVKSRLYTARKKLKETLSKDKKC
HHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EISKAKECEV
CCCCCCCCCC
>Mature Secondary Structure 
SEKELVQKIQSGDMNALGEIFEIYKNQALKYAYLITGNKFTSEDIVQEAFIKCYLSAKS
CHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHH
LKNIEQFKPWFFKILTRLAWKHVGKEKKALPFENIFEKANDESIDKSIDIYIRDQEAETL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCEEEEEECCCHHHH
HAEIEHLDLKQKTVIILFYFNGLTIKEIAKIMGCFEGTVKSRLYTARKKLKETLSKDKKC
HHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EISKAKECEV
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274029; 9384377; 12207695 [H]