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The map label for this gene is dinP

Identifier: 187733383

GI number: 187733383

Start: 236157

End: 237221

Strand: Direct

Name: dinP

Synonym: SbBS512_E0228

Alternate gene names: 187733383

Gene position: 236157-237221 (Clockwise)

Preceding gene: 187732764

Following gene: 187733982

Centisome position: 5.12

GC content: 54.18

Gene sequence:

>1065_bases
GTGTATAAGAAAGTGAAGATTATTCATGTGGATATGGACTGCTTTTTCGCGGCGGTGGAGATGCGCGACAATCCCGCCCT
GCGCGATATCCCTATTGCTATTGGCGGCAGCCGCGAACGTCGGGGGGTGATCAGTACCGCCAATTATCCCGCGCGTAAAT
TTGGCGTACGTAGCGCTATGCCGACAGGGATGGCGCTCAAATTATGCCCGCATCTCACCTTGCTTCCGGGGCGCTTTGAC
GCCTACAAAGAAGCCTCAAATCATATCCGCGAAATCTTCTCGCGCTACACCTCGCGTATTGAACCGTTGTCACTGGATGA
GGCTTATCTCGACGTCACCGATAGCGTCCATTGCCACGGTTCTGCGACCCTCATCGCCCAGGAAATCCGCCAGACGATTT
TCAACGAGCTGCAACTGACGGCGTCTGCGGGCGTGGCACCCGTAAAGTTTCTCGCCAAAATCGCCTCCGACATGAATAAA
CCCAACGGCCAGTTTGTGATTACGCCGGCAGAAGTTCCGGCATTTTTACAAACCTTACCACTGGCAAAAATCCCCGGCGT
CGGCAAAGTCTCGGCGGCAAAACTGGAAGCGATGGGGCTACGAACCTGCGGTGATGTACAAAAGTGTGATCTGGTGATGC
TGCTTAAACGCTTTGGCAAATTTGGCCGCATTTTGTGGGAGCGTAGTCAGGGGATTGACGAGCGCGACGTTAACAGCGAA
CGGTTGCGAAAATCCGTCGGCGTGGAACGCACGATGGCGGAAGATATCCACCACTGGTCTGAATGTGAAGCGATTATCGA
GCGGCTGTATCCGGAACTTGAACGCCGTCTGGCAAAGGTGAAACCTGATTTACTGATTGCTCGCCAGGGGGTGAAATTAA
AGTTTGATGATTTTCAGCAAACCACTCAGGAGCACGTCTGGCCGCGGCTGAATAAAGCTGACTTAATCGCCACCGCGCGT
AAAACCTGGGATGAACGCCGCGGCGGGCGCGGTGTGCGACTGGTGGGGCTGCATGTGACGTTGCTTGACCCGCAAATGGA
AAGACAACTGGTGCTGGGATTATGA

Upstream 100 bases:

>100_bases
GGTAATGCTTTACGGAAGTACTCTGTGAATCCGAATAAGAAGGGCACTTACTGATTTTGCTTTTGTGTGTATAATCTCTT
TGCATGTATAAATACACAGG

Downstream 100 bases:

>100_bases
ATAACATACAAATAAGAGACTATCAGCCTGGCGATTTTCAGCAACTATGCGCTATTTTCATTAGAGCGGTTACGATGACT
GCCAGTCAGCATTATTCACC

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MYKKVKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGVISTANYPARKFGVRSAMPTGMALKLCPHLTLLPGRFD
AYKEASNHIREIFSRYTSRIEPLSLDEAYLDVTDSVHCHGSATLIAQEIRQTIFNELQLTASAGVAPVKFLAKIASDMNK
PNGQFVITPAEVPAFLQTLPLAKIPGVGKVSAAKLEAMGLRTCGDVQKCDLVMLLKRFGKFGRILWERSQGIDERDVNSE
RLRKSVGVERTMAEDIHHWSECEAIIERLYPELERRLAKVKPDLLIARQGVKLKFDDFQQTTQEHVWPRLNKADLIATAR
KTWDERRGGRGVRLVGLHVTLLDPQMERQLVLGL

Sequences:

>Translated_354_residues
MYKKVKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGVISTANYPARKFGVRSAMPTGMALKLCPHLTLLPGRFD
AYKEASNHIREIFSRYTSRIEPLSLDEAYLDVTDSVHCHGSATLIAQEIRQTIFNELQLTASAGVAPVKFLAKIASDMNK
PNGQFVITPAEVPAFLQTLPLAKIPGVGKVSAAKLEAMGLRTCGDVQKCDLVMLLKRFGKFGRILWERSQGIDERDVNSE
RLRKSVGVERTMAEDIHHWSECEAIIERLYPELERRLAKVKPDLLIARQGVKLKFDDFQQTTQEHVWPRLNKADLIATAR
KTWDERRGGRGVRLVGLHVTLLDPQMERQLVLGL
>Mature_354_residues
MYKKVKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGVISTANYPARKFGVRSAMPTGMALKLCPHLTLLPGRFD
AYKEASNHIREIFSRYTSRIEPLSLDEAYLDVTDSVHCHGSATLIAQEIRQTIFNELQLTASAGVAPVKFLAKIASDMNK
PNGQFVITPAEVPAFLQTLPLAKIPGVGKVSAAKLEAMGLRTCGDVQKCDLVMLLKRFGKFGRILWERSQGIDERDVNSE
RLRKSVGVERTMAEDIHHWSECEAIIERLYPELERRLAKVKPDLLIARQGVKLKFDDFQQTTQEHVWPRLNKADLIATAR
KTWDERRGGRGVRLVGLHVTLLDPQMERQLVLGL

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain

Homologues:

Organism=Homo sapiens, GI7705344, Length=356, Percent_Identity=33.4269662921348, Blast_Score=162, Evalue=3e-40,
Organism=Homo sapiens, GI84043967, Length=324, Percent_Identity=31.1728395061728, Blast_Score=158, Evalue=9e-39,
Organism=Homo sapiens, GI7706681, Length=325, Percent_Identity=31.3846153846154, Blast_Score=155, Evalue=4e-38,
Organism=Homo sapiens, GI154350220, Length=249, Percent_Identity=32.5301204819277, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI5729982, Length=354, Percent_Identity=30.5084745762712, Blast_Score=117, Evalue=2e-26,
Organism=Escherichia coli, GI1786425, Length=349, Percent_Identity=100, Blast_Score=721, Evalue=0.0,
Organism=Escherichia coli, GI1787432, Length=217, Percent_Identity=26.2672811059908, Blast_Score=79, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI193205700, Length=403, Percent_Identity=32.0099255583127, Blast_Score=171, Evalue=7e-43,
Organism=Caenorhabditis elegans, GI17537959, Length=294, Percent_Identity=28.9115646258503, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI193205702, Length=351, Percent_Identity=27.6353276353276, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI115534089, Length=156, Percent_Identity=34.6153846153846, Blast_Score=71, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6324921, Length=208, Percent_Identity=29.8076923076923, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI19923006, Length=325, Percent_Identity=31.6923076923077, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI21355641, Length=354, Percent_Identity=29.0960451977401, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24644984, Length=354, Percent_Identity=29.0960451977401, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24668444, Length=124, Percent_Identity=35.4838709677419, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DPO4_SHIB3 (B2U3S3)

Other databases:

- EMBL:   CP001063
- RefSeq:   YP_001879027.1
- EnsemblBacteria:   EBESCT00000073290
- GeneID:   6272955
- GenomeReviews:   CP001063_GR
- KEGG:   sbc:SbBS512_E0228
- GeneTree:   EBGT00050000008599
- HOGENOM:   HBG734504
- OMA:   QAMARQE
- ProtClustDB:   PRK02406
- GO:   GO:0005737
- HAMAP:   MF_01113
- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880
- Gene3D:   G3DSA:3.30.1490.100
- PANTHER:   PTHR11076

Pfam domain/function: PF00817 IMS; SSF100879 DNA_pol_Y-fam_little_finger

EC number: =2.7.7.7

Molecular weight: Translated: 39879; Mature: 39879

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS50173 UMUC

Important sites: ACT_SITE 107-107

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKKVKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGVISTANYPARKFGVRSAM
CCCEEEEEEEEHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCEEECCCCCHHHHCCHHCC
PTGMALKLCPHLTLLPGRFDAYKEASNHIREIFSRYTSRIEPLSLDEAYLDVTDSVHCHG
CCCCHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCEEECC
SATLIAQEIRQTIFNELQLTASAGVAPVKFLAKIASDMNKPNGQFVITPAEVPAFLQTLP
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHCC
LAKIPGVGKVSAAKLEAMGLRTCGDVQKCDLVMLLKRFGKFGRILWERSQGIDERDVNSE
HHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
RLRKSVGVERTMAEDIHHWSECEAIIERLYPELERRLAKVKPDLLIARQGVKLKFDDFQQ
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEHHHHH
TTQEHVWPRLNKADLIATARKTWDERRGGRGVRLVGLHVTLLDPQMERQLVLGL
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCHHHHHHHCCC
>Mature Secondary Structure
MYKKVKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGVISTANYPARKFGVRSAM
CCCEEEEEEEEHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCEEECCCCCHHHHCCHHCC
PTGMALKLCPHLTLLPGRFDAYKEASNHIREIFSRYTSRIEPLSLDEAYLDVTDSVHCHG
CCCCHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCEEECC
SATLIAQEIRQTIFNELQLTASAGVAPVKFLAKIASDMNKPNGQFVITPAEVPAFLQTLP
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHCC
LAKIPGVGKVSAAKLEAMGLRTCGDVQKCDLVMLLKRFGKFGRILWERSQGIDERDVNSE
HHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
RLRKSVGVERTMAEDIHHWSECEAIIERLYPELERRLAKVKPDLLIARQGVKLKFDDFQQ
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEHHHHH
TTQEHVWPRLNKADLIATARKTWDERRGGRGVRLVGLHVTLLDPQMERQLVLGL
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA