Click here to switch to the map view.

The map label for this gene is argD

Identifier: 187730967

GI number: 187730967

Start: 3461075

End: 3462295

Strand: Reverse

Name: argD

Synonym: SbBS512_E3735

Alternate gene names: 187730967

Gene position: 3462295-3461075 (Counterclockwise)

Preceding gene: 187730076

Following gene: 187734020

Centisome position: 75.01

GC content: 54.14

Gene sequence:

>1221_bases
ATGGCAATTGAACAAACAGCAATTACACGCGCGACTTTCGATGAAATGATCCTGCCGATTTATGCTCCGGCAGAGTTTAT
TCCGGTAAAAGGTCAGGGCAGCCGAATCTGGGATCAGCAAGGCAAGGAGTATGTCGATTTCGCGGGTGGCATTGCAGTTA
CGGCGTTGGGCCATTGCCATCCTGCGCTGGTGAACGCGTTAAAAACCCAGGGCGAAACTCTGTGGCATATCAGTAACGTT
TTCACCAATGAACCGGCGCTGCGTCTTGGGCGCAAACTGATTGAGGCGACGTTTGCCGAACGCGTGGTGTTTATGAACTC
CGGCACGGAAGCTAACGAAACCGCCTTTAAACTGGCACGCCATTACGCCTGTGTGCGTCATAGCCCGTTCAAAACCAAAA
TTATTGCCTTCCATAACGCTTTTCATGGTCGCTCGCTGTTTACCGTTTCGGTGGGTGGGCAGCCAAAATATTCCGACGGC
TTTGGGCCGAAACCGGCAGACATCATCCACGTTCCCTTTAACGATCTCCATGCAGTGAAAGCGGTGATGGATGATCACAC
CTGTGCGGTGGTGGTTGAGCCGATCCAGGGCGAGGGCGGTGTGACGGCATCGACGCCAGAGTTTTTGCAGGGCTTGCGCG
AGCTGTGCGATCAACATCAGGCATTATTGGTGTTTGATGAAGTGCAGTGCGGGATGGGGCGGACTGGCGATTTGTTTGCT
TACATGTACTACGGTGTGACGCCGGATATTCTGACTTCTGCGAAAGCGTTAGGCGGCGGCTTCCCGATTAGCGCCATGCT
GACCACGGCGGAAATTGCTTCTGCGTTTCATCCTGGTTCTCACGGTTCCACCTACGGCGGTAATCCTCTGGCCTGTGCAG
TAGCGGGCGCGGCGTTTGATATCATCAATACCCCTGAAGTGCTGGAAGGCATTCAGGCGAAACGCCAGCGTTTTGTTGAC
CATTTGCAGAAGATCGATCAGCAGTACGATGTGTTTAGCGATATTCGCGGTATGGGGCTGTTAATTGGCGCGGAGCTGAA
ACCACACTACAAAGGTCGGGCGCGTGATTTCCTGTATGCGGGTGCAGAGGTTGGCGTAATGGTGCTGAATGCCGGACCGG
ATGTGATGCGTTTAGCACCGTCGCTGGTGGTGGAAGATGCGGATATCGATGAAGGGATGCAACGTTTCGCCCACGCGGTG
GCGAAGGTGGTTGGGGCGTAA

Upstream 100 bases:

>100_bases
TTCCTGCATCTCTGATTTCCGATTGCCATTCAGTGATTTTTTATGCATATTTTGTGATTATAATTTCACATTTATTTATG
CGTAACAGGGTGATCATGAG

Downstream 100 bases:

>100_bases
ATAAGACGCATCAGGCAAAATATGTCGGATGCGGCGTGAATGCCTTATCCGATGGTTTAGCCTGTATTACGCCTTCGAAT
CCCGCAACTTGCGACTCAGC

Product: bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT; DapATase; Succinyldiaminopimelate transferase [H]

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MAIEQTAITRATFDEMILPIYAPAEFIPVKGQGSRIWDQQGKEYVDFAGGIAVTALGHCHPALVNALKTQGETLWHISNV
FTNEPALRLGRKLIEATFAERVVFMNSGTEANETAFKLARHYACVRHSPFKTKIIAFHNAFHGRSLFTVSVGGQPKYSDG
FGPKPADIIHVPFNDLHAVKAVMDDHTCAVVVEPIQGEGGVTASTPEFLQGLRELCDQHQALLVFDEVQCGMGRTGDLFA
YMYYGVTPDILTSAKALGGGFPISAMLTTAEIASAFHPGSHGSTYGGNPLACAVAGAAFDIINTPEVLEGIQAKRQRFVD
HLQKIDQQYDVFSDIRGMGLLIGAELKPHYKGRARDFLYAGAEVGVMVLNAGPDVMRLAPSLVVEDADIDEGMQRFAHAV
AKVVGA

Sequences:

>Translated_406_residues
MAIEQTAITRATFDEMILPIYAPAEFIPVKGQGSRIWDQQGKEYVDFAGGIAVTALGHCHPALVNALKTQGETLWHISNV
FTNEPALRLGRKLIEATFAERVVFMNSGTEANETAFKLARHYACVRHSPFKTKIIAFHNAFHGRSLFTVSVGGQPKYSDG
FGPKPADIIHVPFNDLHAVKAVMDDHTCAVVVEPIQGEGGVTASTPEFLQGLRELCDQHQALLVFDEVQCGMGRTGDLFA
YMYYGVTPDILTSAKALGGGFPISAMLTTAEIASAFHPGSHGSTYGGNPLACAVAGAAFDIINTPEVLEGIQAKRQRFVD
HLQKIDQQYDVFSDIRGMGLLIGAELKPHYKGRARDFLYAGAEVGVMVLNAGPDVMRLAPSLVVEDADIDEGMQRFAHAV
AKVVGA
>Mature_405_residues
AIEQTAITRATFDEMILPIYAPAEFIPVKGQGSRIWDQQGKEYVDFAGGIAVTALGHCHPALVNALKTQGETLWHISNVF
TNEPALRLGRKLIEATFAERVVFMNSGTEANETAFKLARHYACVRHSPFKTKIIAFHNAFHGRSLFTVSVGGQPKYSDGF
GPKPADIIHVPFNDLHAVKAVMDDHTCAVVVEPIQGEGGVTASTPEFLQGLRELCDQHQALLVFDEVQCGMGRTGDLFAY
MYYGVTPDILTSAKALGGGFPISAMLTTAEIASAFHPGSHGSTYGGNPLACAVAGAAFDIINTPEVLEGIQAKRQRFVDH
LQKIDQQYDVFSDIRGMGLLIGAELKPHYKGRARDFLYAGAEVGVMVLNAGPDVMRLAPSLVVEDADIDEGMQRFAHAVA
KVVGA

Specific function: Involved in both the arginine and lysine biosynthetic pathways [H]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=378, Percent_Identity=37.037037037037, Blast_Score=240, Evalue=2e-63,
Organism=Homo sapiens, GI284507298, Length=294, Percent_Identity=38.7755102040816, Blast_Score=195, Evalue=7e-50,
Organism=Homo sapiens, GI13994255, Length=425, Percent_Identity=28.9411764705882, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI37574042, Length=401, Percent_Identity=31.1720698254364, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI226442709, Length=374, Percent_Identity=31.5508021390374, Blast_Score=138, Evalue=7e-33,
Organism=Homo sapiens, GI226442705, Length=401, Percent_Identity=29.925187032419, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI24119277, Length=349, Percent_Identity=28.080229226361, Blast_Score=124, Evalue=2e-28,
Organism=Escherichia coli, GI1789759, Length=406, Percent_Identity=98.5221674876847, Blast_Score=826, Evalue=0.0,
Organism=Escherichia coli, GI1788044, Length=397, Percent_Identity=59.1939546599496, Blast_Score=504, Evalue=1e-144,
Organism=Escherichia coli, GI1789016, Length=413, Percent_Identity=35.8353510895884, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI1787560, Length=404, Percent_Identity=32.4257425742574, Blast_Score=199, Evalue=2e-52,
Organism=Escherichia coli, GI145693181, Length=393, Percent_Identity=34.0966921119593, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1786349, Length=317, Percent_Identity=32.1766561514196, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI1786991, Length=414, Percent_Identity=29.4685990338164, Blast_Score=129, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI25144271, Length=376, Percent_Identity=35.6382978723404, Blast_Score=233, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI32564660, Length=433, Percent_Identity=28.4064665127021, Blast_Score=177, Evalue=9e-45,
Organism=Caenorhabditis elegans, GI25144274, Length=260, Percent_Identity=36.5384615384615, Blast_Score=171, Evalue=6e-43,
Organism=Caenorhabditis elegans, GI71992977, Length=420, Percent_Identity=28.5714285714286, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17541228, Length=435, Percent_Identity=25.2873563218391, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71981843, Length=164, Percent_Identity=32.3170731707317, Blast_Score=88, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6324432, Length=397, Percent_Identity=38.0352644836272, Blast_Score=276, Evalue=5e-75,
Organism=Saccharomyces cerevisiae, GI6323470, Length=403, Percent_Identity=32.258064516129, Blast_Score=214, Evalue=2e-56,
Organism=Saccharomyces cerevisiae, GI6324386, Length=314, Percent_Identity=29.2993630573248, Blast_Score=103, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6321456, Length=439, Percent_Identity=25.0569476082005, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21357415, Length=377, Percent_Identity=34.7480106100796, Blast_Score=222, Evalue=3e-58,
Organism=Drosophila melanogaster, GI28574759, Length=426, Percent_Identity=27.9342723004695, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI161085790, Length=421, Percent_Identity=27.790973871734, Blast_Score=171, Evalue=7e-43,
Organism=Drosophila melanogaster, GI21356575, Length=421, Percent_Identity=30.6413301662708, Blast_Score=158, Evalue=7e-39,
Organism=Drosophila melanogaster, GI281366494, Length=430, Percent_Identity=21.8604651162791, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24667139, Length=430, Percent_Identity=21.8604651162791, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24667143, Length=430, Percent_Identity=21.8604651162791, Blast_Score=89, Evalue=5e-18,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR017652 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11; =2.6.1.17 [H]

Molecular weight: Translated: 43845; Mature: 43713

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIEQTAITRATFDEMILPIYAPAEFIPVKGQGSRIWDQQGKEYVDFAGGIAVTALGHCH
CCCCHHHHHHHHHHHHHEEEECCCEEEEECCCCCCCHHHCCCHHHHHCCCHHEEHHHCCC
PALVNALKTQGETLWHISNVFTNEPALRLGRKLIEATFAERVVFMNSGTEANETAFKLAR
HHHHHHHHHCCCEEEEEHHHHCCCHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHH
HYACVRHSPFKTKIIAFHNAFHGRSLFTVSVGGQPKYSDGFGPKPADIIHVPFNDLHAVK
HHHHHCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCEEECCCHHHHHHH
AVMDDHTCAVVVEPIQGEGGVTASTPEFLQGLRELCDQHQALLVFDEVQCGMGRTGDLFA
HHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEHHCCCCCCCCEEE
YMYYGVTPDILTSAKALGGGFPISAMLTTAEIASAFHPGSHGSTYGGNPLACAVAGAAFD
EEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEHHHHHC
IINTPEVLEGIQAKRQRFVDHLQKIDQQYDVFSDIRGMGLLIGAELKPHYKGRARDFLYA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHEEE
GAEVGVMVLNAGPDVMRLAPSLVVEDADIDEGMQRFAHAVAKVVGA
CCCCCEEEEECCCHHHHHCHHHEEECCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AIEQTAITRATFDEMILPIYAPAEFIPVKGQGSRIWDQQGKEYVDFAGGIAVTALGHCH
CCCHHHHHHHHHHHHHEEEECCCEEEEECCCCCCCHHHCCCHHHHHCCCHHEEHHHCCC
PALVNALKTQGETLWHISNVFTNEPALRLGRKLIEATFAERVVFMNSGTEANETAFKLAR
HHHHHHHHHCCCEEEEEHHHHCCCHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHH
HYACVRHSPFKTKIIAFHNAFHGRSLFTVSVGGQPKYSDGFGPKPADIIHVPFNDLHAVK
HHHHHCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCEEECCCHHHHHHH
AVMDDHTCAVVVEPIQGEGGVTASTPEFLQGLRELCDQHQALLVFDEVQCGMGRTGDLFA
HHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEHHCCCCCCCCEEE
YMYYGVTPDILTSAKALGGGFPISAMLTTAEIASAFHPGSHGSTYGGNPLACAVAGAAFD
EEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEHHHHHC
IINTPEVLEGIQAKRQRFVDHLQKIDQQYDVFSDIRGMGLLIGAELKPHYKGRARDFLYA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHEEE
GAEVGVMVLNAGPDVMRLAPSLVVEDADIDEGMQRFAHAVAKVVGA
CCCCCEEEEECCCHHHHHCHHHEEECCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]