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The map label for this gene is pabA

Identifier: 187730076

GI number: 187730076

Start: 3462381

End: 3462944

Strand: Reverse

Name: pabA

Synonym: SbBS512_E3736

Alternate gene names: 187730076

Gene position: 3462944-3462381 (Counterclockwise)

Preceding gene: 187731752

Following gene: 187730967

Centisome position: 75.02

GC content: 53.55

Gene sequence:

>564_bases
ATGATCCTGCTTATTGATAACTACGATTCTTTTACCTGGAACCTCTACCAGTACTTTTGTGAACTGGGGGCGGATGTGCT
GGTTAAGCGCAACGATGCGTTGACGTTGGCGGATATCGACGCCCTTAAACCACAAAAAATTGTCATCTCACCCGGCCCCT
GTACGCCAGATGAAGCCGGGATCTCCCTTGACGTTATTCGCCACTATGCCGGGCGCTTGCCGATTCTTGGCGTCTGCCTC
GGTCATCAGGCAATGGCGCAGGCATTTGGCGGTAAAGTTGTGCGCGCCGCAAAGGTCATGCACGGCAAAACCTCGCCGAT
TACACATAACGGTGAGGGCGTATTTCGGGGGCTGGCAAATCCACTTACCGTGACACGCTACCATTCGCTGGTGGTGGAAC
CTGGCTCATTACCAGCGTGCTTTGACGTGACGGCCTGGAGCGAAACCCGCGAGATTATGGGGATTCGCCATCGCCAGTGG
GATCTGGAAGGTGTGCAGTTCCATCCAGAAAGTATTCTTAGCGAACAAGGACATCAACTGCTGGCTAATTTCCTGCATCT
CTGA

Upstream 100 bases:

>100_bases
ATGGGGGATCTCACCGCACTGCAGATGATATTTAGCAAAGTGGTAAGCGAAGCCGGGGAATCTGAGTAAAATAGCGCGGT
TCTTTCGTACCGGAGCCGCC

Downstream 100 bases:

>100_bases
TTTCCGATTGCCATTCAGTGATTTTTTATGCATATTTTGTGATTATAATTTCACATTTATTTATGCGTAACAGGGTGATC
ATGAGATGGCAATTGAACAA

Product: para-aminobenzoate synthase component II

Products: NA

Alternate protein names: ADC synthase [H]

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MILLIDNYDSFTWNLYQYFCELGADVLVKRNDALTLADIDALKPQKIVISPGPCTPDEAGISLDVIRHYAGRLPILGVCL
GHQAMAQAFGGKVVRAAKVMHGKTSPITHNGEGVFRGLANPLTVTRYHSLVVEPGSLPACFDVTAWSETREIMGIRHRQW
DLEGVQFHPESILSEQGHQLLANFLHL

Sequences:

>Translated_187_residues
MILLIDNYDSFTWNLYQYFCELGADVLVKRNDALTLADIDALKPQKIVISPGPCTPDEAGISLDVIRHYAGRLPILGVCL
GHQAMAQAFGGKVVRAAKVMHGKTSPITHNGEGVFRGLANPLTVTRYHSLVVEPGSLPACFDVTAWSETREIMGIRHRQW
DLEGVQFHPESILSEQGHQLLANFLHL
>Mature_187_residues
MILLIDNYDSFTWNLYQYFCELGADVLVKRNDALTLADIDALKPQKIVISPGPCTPDEAGISLDVIRHYAGRLPILGVCL
GHQAMAQAFGGKVVRAAKVMHGKTSPITHNGEGVFRGLANPLTVTRYHSLVVEPGSLPACFDVTAWSETREIMGIRHRQW
DLEGVQFHPESILSEQGHQLLANFLHL

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=186, Percent_Identity=99.4623655913979, Blast_Score=386, Evalue=1e-109,
Organism=Escherichia coli, GI1787517, Length=187, Percent_Identity=43.8502673796791, Blast_Score=150, Evalue=6e-38,
Organism=Saccharomyces cerevisiae, GI6322638, Length=187, Percent_Identity=51.8716577540107, Blast_Score=222, Evalue=2e-59,
Organism=Saccharomyces cerevisiae, GI6324361, Length=213, Percent_Identity=32.3943661971831, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 20671; Mature: 20671

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS00442 GATASE_TYPE_I ; PS00678 WD_REPEATS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILLIDNYDSFTWNLYQYFCELGADVLVKRNDALTLADIDALKPQKIVISPGPCTPDEAG
CEEEEECCCCCHHHHHHHHHHCCCCEEEECCCCEEEEECCCCCCCEEEECCCCCCCCCCC
ISLDVIRHYAGRLPILGVCLGHQAMAQAFGGKVVRAAKVMHGKTSPITHNGEGVFRGLAN
CCHHHHHHHHCCCCEEEHHHCHHHHHHHHCCHHHHHHHHHCCCCCCCEECCCHHHHHCCC
PLTVTRYHSLVVEPGSLPACFDVTAWSETREIMGIRHRQWDLEGVQFHPESILSEQGHQL
CEEEEEEEEEEECCCCCCCEEEECCHHHHHHHHCCCCCCCCCCCEEECHHHHHHHHHHHH
LANFLHL
HHHHHCC
>Mature Secondary Structure
MILLIDNYDSFTWNLYQYFCELGADVLVKRNDALTLADIDALKPQKIVISPGPCTPDEAG
CEEEEECCCCCHHHHHHHHHHCCCCEEEECCCCEEEEECCCCCCCEEEECCCCCCCCCCC
ISLDVIRHYAGRLPILGVCLGHQAMAQAFGGKVVRAAKVMHGKTSPITHNGEGVFRGLAN
CCHHHHHHHHCCCCEEEHHHCHHHHHHHHCCHHHHHHHHHCCCCCCCEECCCHHHHHCCC
PLTVTRYHSLVVEPGSLPACFDVTAWSETREIMGIRHRQWDLEGVQFHPESILSEQGHQL
CEEEEEEEEEEECCCCCCCEEEECCHHHHHHHHCCCCCCCCCCCEEECHHHHHHHHHHHH
LANFLHL
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6350604; 2403545; 9278503; 2546924; 8096767 [H]