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The map label for this gene is cusB

Identifier: 187730717

GI number: 187730717

Start: 449742

End: 450869

Strand: Direct

Name: cusB

Synonym: SbBS512_E0468

Alternate gene names: 187730717

Gene position: 449742-450869 (Clockwise)

Preceding gene: 187732768

Following gene: 187731101

Centisome position: 9.74

GC content: 55.94

Gene sequence:

>1128_bases
TTGGCAGCATTACCCGCAGAACGTAAAATCTTATTCTGGTACGACCCGATGTACCCCAATACGCGGTTCGATAAACCAGG
TAAATCGCCGTTTATGGATATGGATCTGGTGCCGAAATATGCCGATGAAGAGAGTTCTGCGTCTGGTGTGCGCATTGACC
CGACTCAGACGCAGAATCTGGGGGTGAAAACGGCTACCGTCACGCGCGGACCGCTGACTTTTGCCCAGAGTTTCCCGGCG
AATGTCAGTTACAACGAGTATCAGTATGCCATTGTGCAGGCTCGCGCTGCCGGGTTTATCGACAAGGTGTATCCGCTTAC
CGTGGGCGATAAAGTACAAAAGGGCACACCGCTTCTCGACCTGACCATTCCTGACTGGGTGGAAGCGCAGAGTGAGTATT
TACTGCTGCGCGAAACCGGCGGTACGGCGACCCAGACTGAAGGCATTCTTGAGCGGCTGCGACTGGCGGGAATGCCGGAG
GCGGATATTCGCCGCCTGATCGCCACGCAAAAAATCCAGACTCGCTTTACGCTCAAAGCGCCCATTGATGGCGTGATCAC
CGCGTTTGATCTGCGCGCGGGAATGAATATCGCCAAAGATAACGTGGTAGCGAAAATTCAGGGTATGGACCCGGTGTGGG
TCACTGCTGCGATCCCGGAGTCTATCGCCTGGCTGGTGAAAGATGCCTCGCAGTTTACGCTCACCGTTCCGGCACGACCG
GATAAAACACTCACCATCCGCAAATGGACGCTGCTACCCGGCGTGGATGCCGCGACCTGCACGCTGCAGCTGCGTCTGGA
AGTCGACAACGCCGACGAGGCGCTAAAACCGGGCATGAACGCCTGGTTGCAACTCAATACCGCCAGCGAACCGATGCTGC
TCATTCCGTCACAAGGGCTGATTGATACCGGTAGCGAACAGCGGGTGATTACCATTGATGCCGACGGGCGCTTTGTACCG
AAACGCGTTGCCGTTTTCCAGGCATCGCAAGGTGTCACCGCATTACGCTCTGGTCTGGCGGAAGGTGAAAAGGTGGTTTC
CAGCGGCCTTTTCCTGATTGATTCCGAAGCCAATATTTCTGGCGCACTGGAGCGGATGCGCTCTGAAAGTGCTACCCATG
CGCATTGA

Upstream 100 bases:

>100_bases
TTACGCACCACGCCTTCAGTAGCGGAGCAGGAAGGACATCTGATGGAAATGGAAGCCACGCAAGCACCTTAAAATCACCA
TCATACACTAAATCAGTAAG

Downstream 100 bases:

>100_bases
GGGAATAACCAATGATTGAATGGATTATTCGTCGCTCGGTGGCGAACCGTTTTTTGGTGCTGATGGGCGCGTTGTTTCTT
AGCATCTGGGGCACCTGGAC

Product: copper/silver efflux system membrane fusion protein CusB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MAALPAERKILFWYDPMYPNTRFDKPGKSPFMDMDLVPKYADEESSASGVRIDPTQTQNLGVKTATVTRGPLTFAQSFPA
NVSYNEYQYAIVQARAAGFIDKVYPLTVGDKVQKGTPLLDLTIPDWVEAQSEYLLLRETGGTATQTEGILERLRLAGMPE
ADIRRLIATQKIQTRFTLKAPIDGVITAFDLRAGMNIAKDNVVAKIQGMDPVWVTAAIPESIAWLVKDASQFTLTVPARP
DKTLTIRKWTLLPGVDAATCTLQLRLEVDNADEALKPGMNAWLQLNTASEPMLLIPSQGLIDTGSEQRVITIDADGRFVP
KRVAVFQASQGVTALRSGLAEGEKVVSSGLFLIDSEANISGALERMRSESATHAH

Sequences:

>Translated_375_residues
MAALPAERKILFWYDPMYPNTRFDKPGKSPFMDMDLVPKYADEESSASGVRIDPTQTQNLGVKTATVTRGPLTFAQSFPA
NVSYNEYQYAIVQARAAGFIDKVYPLTVGDKVQKGTPLLDLTIPDWVEAQSEYLLLRETGGTATQTEGILERLRLAGMPE
ADIRRLIATQKIQTRFTLKAPIDGVITAFDLRAGMNIAKDNVVAKIQGMDPVWVTAAIPESIAWLVKDASQFTLTVPARP
DKTLTIRKWTLLPGVDAATCTLQLRLEVDNADEALKPGMNAWLQLNTASEPMLLIPSQGLIDTGSEQRVITIDADGRFVP
KRVAVFQASQGVTALRSGLAEGEKVVSSGLFLIDSEANISGALERMRSESATHAH
>Mature_374_residues
AALPAERKILFWYDPMYPNTRFDKPGKSPFMDMDLVPKYADEESSASGVRIDPTQTQNLGVKTATVTRGPLTFAQSFPAN
VSYNEYQYAIVQARAAGFIDKVYPLTVGDKVQKGTPLLDLTIPDWVEAQSEYLLLRETGGTATQTEGILERLRLAGMPEA
DIRRLIATQKIQTRFTLKAPIDGVITAFDLRAGMNIAKDNVVAKIQGMDPVWVTAAIPESIAWLVKDASQFTLTVPARPD
KTLTIRKWTLLPGVDAATCTLQLRLEVDNADEALKPGMNAWLQLNTASEPMLLIPSQGLIDTGSEQRVITIDADGRFVPK
RVAVFQASQGVTALRSGLAEGEKVVSSGLFLIDSEANISGALERMRSESATHAH

Specific function: Part of a cation efflux system that mediates resistance to copper and silver [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=370, Percent_Identity=99.1891891891892, Blast_Score=748, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 40993; Mature: 40862

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAALPAERKILFWYDPMYPNTRFDKPGKSPFMDMDLVPKYADEESSASGVRIDPTQTQNL
CCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCC
GVKTATVTRGPLTFAQSFPANVSYNEYQYAIVQARAAGFIDKVYPLTVGDKVQKGTPLLD
CEEEEEEECCCCHHHHCCCCCCCCCCEEEEEEEEHHHCCHHHEEEEECCCCCCCCCCEEE
LTIPDWVEAQSEYLLLRETGGTATQTEGILERLRLAGMPEADIRRLIATQKIQTRFTLKA
EECCHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEEEEEEEC
PIDGVITAFDLRAGMNIAKDNVVAKIQGMDPVWVTAAIPESIAWLVKDASQFTLTVPARP
CCCCEEEEEEHHCCCCCCCCCEEEEEECCCCEEEEEECCHHHHHHHCCCCEEEEEECCCC
DKTLTIRKWTLLPGVDAATCTLQLRLEVDNADEALKPGMNAWLQLNTASEPMLLIPSQGL
CCEEEEEEEEECCCCCCEEEEEEEEEEECCCHHHHCCCCCEEEEEECCCCCEEEECCCCC
IDTGSEQRVITIDADGRFVPKRVAVFQASQGVTALRSGLAEGEKVVSSGLFLIDSEANIS
CCCCCCCEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCEEEEECCCCHH
GALERMRSESATHAH
HHHHHHHHCCCCCCC
>Mature Secondary Structure 
AALPAERKILFWYDPMYPNTRFDKPGKSPFMDMDLVPKYADEESSASGVRIDPTQTQNL
CCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCC
GVKTATVTRGPLTFAQSFPANVSYNEYQYAIVQARAAGFIDKVYPLTVGDKVQKGTPLLD
CEEEEEEECCCCHHHHCCCCCCCCCCEEEEEEEEHHHCCHHHEEEEECCCCCCCCCCEEE
LTIPDWVEAQSEYLLLRETGGTATQTEGILERLRLAGMPEADIRRLIATQKIQTRFTLKA
EECCHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEEEEEEEC
PIDGVITAFDLRAGMNIAKDNVVAKIQGMDPVWVTAAIPESIAWLVKDASQFTLTVPARP
CCCCEEEEEEHHCCCCCCCCCEEEEEECCCCEEEEEECCHHHHHHHCCCCEEEEEECCCC
DKTLTIRKWTLLPGVDAATCTLQLRLEVDNADEALKPGMNAWLQLNTASEPMLLIPSQGL
CCEEEEEEEEECCCCCCEEEEEEEEEEECCCHHHHCCCCCEEEEEECCCCCEEEECCCCC
IDTGSEQRVITIDADGRFVPKRVAVFQASQGVTALRSGLAEGEKVVSSGLFLIDSEANIS
CCCCCCCEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCEEEEECCCCHH
GALERMRSESATHAH
HHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]