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The map label for this gene is atsA [H]

Identifier: 187734998

GI number: 187734998

Start: 580886

End: 582388

Strand: Direct

Name: atsA [H]

Synonym: Amuc_0491

Alternate gene names: 187734998

Gene position: 580886-582388 (Clockwise)

Preceding gene: 187734996

Following gene: 187734999

Centisome position: 21.8

GC content: 56.15

Gene sequence:

>1503_bases
ATGGTCACATTTTACAATATCACTCTCTCTACCGCCTTTTCCCTGCTGATGCTGTCCGTGGCGGAAGCGGCACGGCCCAA
TGTGGTTCTCATCAATGCGGATGACCTTGGCTGGGCGGAAGTGGGCTGCTACGGCCAGAAAAAAATTAAAACCCCGAACA
TTGACAAGCTGGCCTCCGAAGGACAGCGATGGGTTTATTTCTATTCCGGAGCTCCGGTTTGTTCCCCTTCCCGCAATGTG
CTGATGACGGGCAAGCATACGGGCAACTGCGACGTACAGGATTTGAAACGCGTGGACGCGGGCGAAAACTGGCGCGACCT
CAAAGGAGACTGGCCCATCAGAACGGAAACCTACACTCTACCGGAAGCCATGAAAAAAGCCGGTTACGCCACAGCGGTGT
TCGGTAAATGGGGTATTGGGGATTTCGGTTCCACCGGAGCGCCGGACAAACACGGCGTGGACAGGTTCTATGGCTACACG
GACCAGAAAGCCTGCCACACCTACTATCCTCCATACCTCTGGAATGACGGAAAGAAGGAAGTTCTCAACACTTCCCTGAC
AGCCGCCACTATCGGACACGGTTCCCAGCCCAAAGGGGAAGTTCTGGCGGACACCTACCGCGCGGAACAACACAGTTCCG
ATCTTATTGCGGATAAAATGCTGGAATTTGTGAAGGAAAAGGCCCATGGCAAACAACCGTTTTTCCTGTATTACGCCCCG
CTGGAACCCCATGTGGCCATGCAGCCTCTTCAGGAATGGATTGACCGCTATCCCCGCGAATGGGACAAATCCCCCTACCG
CGGCAACCGGGGCTATCTGCCCCATCCCCGCCCCCGGGCCGCCTATGCAGGCATGATTTCCCAGATGGACCACAACGTAG
GACGCCTGCTGGACACGCTGAAAGCCTGTGGCCTGGACAAAAATACCATCGTCATTTTTACCAGCGACAACGGCACCACG
CATGATGCAGGGGGGGTGGACCACCGGTTCTTCAACTCCGTAGCCGATCTCAAAGGTTTGAAAGGGCAGCTTTATGAAGG
CGGTATACGTGTCCCCGGCATTATCCGCTGGCCTGGGAAAATAGCCCCGGGAAAAACCATCACCCAGCCGGCCTTCCATG
CGGACGTGATGCCTACACTGTGCGCTCTGACAGGAGCGGATGCAGGTTCTCCGCTGGGAACGGACCTCTCCCCTGTCCTT
CTGGGCAAAAAATCCGCTCTGCATGACAGGAAGCCCCTGGTCTGGGCAGGGGGAGGCTACGGCGGCCAGGTAGCCGTGCG
TTTCGACTCCAAGAAAGTCATCCGCCGCAACCTGTTTCCCGGTAAAAAACCGGACAACTGGGAAGTGTACGATATCGTGA
AAGACCCCGCAGAGAAAAATAATATCGCCGCAGAAAACCGTGACCTTATCAACAGAGCCATCGCCATTCTGGACAGGGAA
TATCAACCCGCGCCCGGCTTCCAGGCCCTGCGTTACAAGGCCCCGGAACAGGTAGCCGAATAA

Upstream 100 bases:

>100_bases
CCGAAAGGCTCACCCTGTGAGCATCTCATCCGGCATCCGGTAAGGAAAACGAAACTATTTTTTGAAACAAGGAAGAGTGT
TTCTCCGTTATTATTACCGT

Downstream 100 bases:

>100_bases
GAGAACGGGAAAGAAGGTTCCACGATCCGCCTCCTTCGCCATTCTGACCTTGACGTGAACGGAGCCGGGGTTAGTCTTTC
ACGCATGAGTTTGACATCAT

Product: sulfatase

Products: NA

Alternate protein names: AS; Aryl-sulfate sulphohydrolase [H]

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MVTFYNITLSTAFSLLMLSVAEAARPNVVLINADDLGWAEVGCYGQKKIKTPNIDKLASEGQRWVYFYSGAPVCSPSRNV
LMTGKHTGNCDVQDLKRVDAGENWRDLKGDWPIRTETYTLPEAMKKAGYATAVFGKWGIGDFGSTGAPDKHGVDRFYGYT
DQKACHTYYPPYLWNDGKKEVLNTSLTAATIGHGSQPKGEVLADTYRAEQHSSDLIADKMLEFVKEKAHGKQPFFLYYAP
LEPHVAMQPLQEWIDRYPREWDKSPYRGNRGYLPHPRPRAAYAGMISQMDHNVGRLLDTLKACGLDKNTIVIFTSDNGTT
HDAGGVDHRFFNSVADLKGLKGQLYEGGIRVPGIIRWPGKIAPGKTITQPAFHADVMPTLCALTGADAGSPLGTDLSPVL
LGKKSALHDRKPLVWAGGGYGGQVAVRFDSKKVIRRNLFPGKKPDNWEVYDIVKDPAEKNNIAAENRDLINRAIAILDRE
YQPAPGFQALRYKAPEQVAE

Sequences:

>Translated_500_residues
MVTFYNITLSTAFSLLMLSVAEAARPNVVLINADDLGWAEVGCYGQKKIKTPNIDKLASEGQRWVYFYSGAPVCSPSRNV
LMTGKHTGNCDVQDLKRVDAGENWRDLKGDWPIRTETYTLPEAMKKAGYATAVFGKWGIGDFGSTGAPDKHGVDRFYGYT
DQKACHTYYPPYLWNDGKKEVLNTSLTAATIGHGSQPKGEVLADTYRAEQHSSDLIADKMLEFVKEKAHGKQPFFLYYAP
LEPHVAMQPLQEWIDRYPREWDKSPYRGNRGYLPHPRPRAAYAGMISQMDHNVGRLLDTLKACGLDKNTIVIFTSDNGTT
HDAGGVDHRFFNSVADLKGLKGQLYEGGIRVPGIIRWPGKIAPGKTITQPAFHADVMPTLCALTGADAGSPLGTDLSPVL
LGKKSALHDRKPLVWAGGGYGGQVAVRFDSKKVIRRNLFPGKKPDNWEVYDIVKDPAEKNNIAAENRDLINRAIAILDRE
YQPAPGFQALRYKAPEQVAE
>Mature_500_residues
MVTFYNITLSTAFSLLMLSVAEAARPNVVLINADDLGWAEVGCYGQKKIKTPNIDKLASEGQRWVYFYSGAPVCSPSRNV
LMTGKHTGNCDVQDLKRVDAGENWRDLKGDWPIRTETYTLPEAMKKAGYATAVFGKWGIGDFGSTGAPDKHGVDRFYGYT
DQKACHTYYPPYLWNDGKKEVLNTSLTAATIGHGSQPKGEVLADTYRAEQHSSDLIADKMLEFVKEKAHGKQPFFLYYAP
LEPHVAMQPLQEWIDRYPREWDKSPYRGNRGYLPHPRPRAAYAGMISQMDHNVGRLLDTLKACGLDKNTIVIFTSDNGTT
HDAGGVDHRFFNSVADLKGLKGQLYEGGIRVPGIIRWPGKIAPGKTITQPAFHADVMPTLCALTGADAGSPLGTDLSPVL
LGKKSALHDRKPLVWAGGGYGGQVAVRFDSKKVIRRNLFPGKKPDNWEVYDIVKDPAEKNNIAAENRDLINRAIAILDRE
YQPAPGFQALRYKAPEQVAE

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI146229331, Length=395, Percent_Identity=33.9240506329114, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI146229329, Length=395, Percent_Identity=33.9240506329114, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI6005990, Length=395, Percent_Identity=33.9240506329114, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI146229324, Length=395, Percent_Identity=33.9240506329114, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI157266309, Length=443, Percent_Identity=27.765237020316, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI53831991, Length=536, Percent_Identity=27.7985074626866, Blast_Score=149, Evalue=9e-36,
Organism=Homo sapiens, GI4503899, Length=423, Percent_Identity=28.3687943262411, Blast_Score=144, Evalue=3e-34,
Organism=Homo sapiens, GI38569407, Length=371, Percent_Identity=29.6495956873315, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI38569405, Length=371, Percent_Identity=29.6495956873315, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI45430057, Length=435, Percent_Identity=30.3448275862069, Blast_Score=134, Evalue=3e-31,
Organism=Homo sapiens, GI71852584, Length=443, Percent_Identity=26.86230248307, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI31742482, Length=470, Percent_Identity=25.3191489361702, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI58743319, Length=455, Percent_Identity=26.1538461538462, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI109389362, Length=365, Percent_Identity=27.9452054794521, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI59797060, Length=493, Percent_Identity=25.9634888438134, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI71852586, Length=162, Percent_Identity=37.6543209876543, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI146229327, Length=313, Percent_Identity=32.5878594249201, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI4557659, Length=378, Percent_Identity=26.7195767195767, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI5360208, Length=334, Percent_Identity=27.5449101796407, Blast_Score=88, Evalue=2e-17,
Organism=Escherichia coli, GI1790233, Length=386, Percent_Identity=27.2020725388601, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1790112, Length=474, Percent_Identity=25.7383966244726, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI87081924, Length=435, Percent_Identity=25.9770114942529, Blast_Score=96, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI115533416, Length=462, Percent_Identity=26.1904761904762, Blast_Score=121, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI115533418, Length=454, Percent_Identity=25.7709251101322, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17559078, Length=115, Percent_Identity=34.7826086956522, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24666109, Length=398, Percent_Identity=31.9095477386935, Blast_Score=156, Evalue=3e-38,
Organism=Drosophila melanogaster, GI281363223, Length=386, Percent_Identity=27.979274611399, Blast_Score=138, Evalue=1e-32,
Organism=Drosophila melanogaster, GI281366397, Length=401, Percent_Identity=29.1770573566085, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI281366395, Length=401, Percent_Identity=29.1770573566085, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24666163, Length=401, Percent_Identity=29.1770573566085, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24666175, Length=416, Percent_Identity=27.6442307692308, Blast_Score=120, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: =3.1.6.1 [H]

Molecular weight: Translated: 55362; Mature: 55362

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: PS00523 SULFATASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTFYNITLSTAFSLLMLSVAEAARPNVVLINADDLGWAEVGCYGQKKIKTPNIDKLASE
CEEEEEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHCCCCCCCCCCCCHHHHHCC
GQRWVYFYSGAPVCSPSRNVLMTGKHTGNCDVQDLKRVDAGENWRDLKGDWPIRTETYTL
CCEEEEEECCCCCCCCCCCEEEECCCCCCCCHHHHHHCCCCCCCHHCCCCCCCCCCEEEC
PEAMKKAGYATAVFGKWGIGDFGSTGAPDKHGVDRFYGYTDQKACHTYYPPYLWNDGKKE
HHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCEECCCHHH
VLNTSLTAATIGHGSQPKGEVLADTYRAEQHSSDLIADKMLEFVKEKAHGKQPFFLYYAP
HHHCCHHEEECCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCEEEEECC
LEPHVAMQPLQEWIDRYPREWDKSPYRGNRGYLPHPRPRAAYAGMISQMDHNVGRLLDTL
CCCCHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KACGLDKNTIVIFTSDNGTTHDAGGVDHRFFNSVADLKGLKGQLYEGGIRVPGIIRWPGK
HHCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCHHCCCCCCCCEEEECCCC
IAPGKTITQPAFHADVMPTLCALTGADAGSPLGTDLSPVLLGKKSALHDRKPLVWAGGGY
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCHHHHCCCCCEEEECCCC
GGQVAVRFDSKKVIRRNLFPGKKPDNWEVYDIVKDPAEKNNIAAENRDLINRAIAILDRE
CCEEEEEECCHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCC
YQPAPGFQALRYKAPEQVAE
CCCCCCHHHHHCCCHHHHCC
>Mature Secondary Structure
MVTFYNITLSTAFSLLMLSVAEAARPNVVLINADDLGWAEVGCYGQKKIKTPNIDKLASE
CEEEEEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHCCCCCCCCCCCCHHHHHCC
GQRWVYFYSGAPVCSPSRNVLMTGKHTGNCDVQDLKRVDAGENWRDLKGDWPIRTETYTL
CCEEEEEECCCCCCCCCCCEEEECCCCCCCCHHHHHHCCCCCCCHHCCCCCCCCCCEEEC
PEAMKKAGYATAVFGKWGIGDFGSTGAPDKHGVDRFYGYTDQKACHTYYPPYLWNDGKKE
HHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCEECCCHHH
VLNTSLTAATIGHGSQPKGEVLADTYRAEQHSSDLIADKMLEFVKEKAHGKQPFFLYYAP
HHHCCHHEEECCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCEEEEECC
LEPHVAMQPLQEWIDRYPREWDKSPYRGNRGYLPHPRPRAAYAGMISQMDHNVGRLLDTL
CCCCHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KACGLDKNTIVIFTSDNGTTHDAGGVDHRFFNSVADLKGLKGQLYEGGIRVPGIIRWPGK
HHCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCHHCCCCCCCCEEEECCCC
IAPGKTITQPAFHADVMPTLCALTGADAGSPLGTDLSPVLLGKKSALHDRKPLVWAGGGY
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCHHHHCCCCCEEEECCCC
GGQVAVRFDSKKVIRRNLFPGKKPDNWEVYDIVKDPAEKNNIAAENRDLINRAIAILDRE
CCEEEEEECCHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCC
YQPAPGFQALRYKAPEQVAE
CCCCCCHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7744061; 10984043 [H]