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The map label for this gene is dsbD [H]

Identifier: 187734851

GI number: 187734851

Start: 403467

End: 405797

Strand: Direct

Name: dsbD [H]

Synonym: Amuc_0343

Alternate gene names: 187734851

Gene position: 403467-405797 (Clockwise)

Preceding gene: 187734848

Following gene: 187734859

Centisome position: 15.14

GC content: 59.37

Gene sequence:

>2331_bases
ATGGTAACCGCCTTTGCTATGAGAAACTTTTTGAAAGCAGCCGTCGGCTGCCTGGGCATGATCGCCGGGTGTTTCAGTAC
GGGGGAGGCCCAGGACTTCGGAGGCATGAGCTTCGGGGAAGCGGGAAACTTTGGTCCGCCCCAGACATCCGGTTCCTCCA
AGGCCACTGTCACCTCCTATGGAGAAGCCTCCTTCGTCATCGTGACGGAGCTGGCGCTGCCGGACCACTGGCACGTTTAC
TATAAAAATCCGGGAACCGTGGGCCTTCCCATGGAAGCCGCTCTCCAGCCTGTGCCCGGCTTCCGGGTGGAAGGCCCCTT
CTGGCAAATCCCGGAACTGGAGAAAGGGCTTGTGGATTTTTACGGATACAGCGGAAAAGCCAAAATGGCGTTCCGGGTGA
CTCCGGAAAAGGATGCCCCCCCGGAAGCGACGTTCATCACCACCATGACATGGCAAATGTGCGCGGAACAGTGCGCCGCC
CCGGAAACCAAAAACTTCAGCGTCACACTGAAGCGCGGAGACGGGCAGACAGCCCCTGACGCGGCGGAATTGACCGGAAA
CATGGCAGGGCTTGCCGCCCCCGACTGGGCGGAAGGGCTGAAAGCCCGGATTTCCCAGGAAGGGAAAACCGTCACCCTGC
ACCTCAGGACAAACGGACGCCCCGTTCCGCAGGATTCCGTCTATTTTTTCTGCAATCAGGGGGAAATCAACCCTACCACT
CCCCAAATCTTCAAAAAACTGGATGACTCCAATTATGAGCTGTCCATGCAATTCAATGACACCACGGACGGCCTTTACCC
CAACAACCTGCCGGATGCAGACAGGGGAAAACCGCTGACCAGCCTTTCCGGCATCCTGCGCGCCGGCAGGGAAGGCATCA
TCATCACCGCGGACGACCGCCCCTTCTCCGGGGAATCTCAGTCAACAGCCGCCGGAACGGAATCCGCCCCGGAACCTTCC
GCTTCCATCCCCGCTCCTCCGCTGATGGGCCTGGGGGAAATCATGTTCTTCATGTTCATCGGCGGCATCATCCTCAATGT
CATGCCGTGCGTCTTCCCGGTAATCGGCCTCAAGATTATGGGATTCGTCCAGCTGGGAGGGGGGGAACGGAAAAAAGTGC
TGGCCCACTCCCTTACCTTCGTACTGGGCATCCTGATTTCTTTCTGGCTCATTACTGCCATTCTGATTGCGCTGAAAGCG
AACATGTTTGACTGGAGCGCCCCAGCCGGCCCCGGCGTGTTCAGCGGAGACTTCTGGCTGGGCCGCGGCGCGGAGGGCGT
TGTCAACTGGGCGTTCTGGTTTGAAAACCCCTGGGTGAATTTCTGCCTGCTGGGCCTGATGCTCGCCATGGGGCTGAGCA
TGTTCGGCGTCTTTGAAATAGGCGTCAAAGCCACGACCATGGGCAACGACCTCCAGCACCGGAAGGGTTATGCCGGCTCC
TTCTGGTCCGGCGCCCTGGCTACGGTCATCTCCACCCCGTGCAGCGCTCCGTTCCTGGGCCAGGCTATCGGCGCGGCCAT
GCTCCAGCCGCCGCTGGGCATCGTGCTCTGCCTGACCATGATGGGGCTTGGAATGTCCCTTCCCTACATCATTCTGGGAG
CCTTTCCCGTCCTGACCAGATACCTGCCCAAACCCGGCGCATGGATGGAATCCTTCAAGCAGTCCATGTCCTTCCTGATG
TTCGGCACCGCAGCCTACTTCCTCTGGATTTACATGGCCTTCTTTGATGCAGAAAACCATCCTCAGGACATCCTGTTCCT
CTTCTTCGGGCTTGTGCTGTTTTCCATGGCCTTTTGGGTATACGGCAGATGGTGCCCCATGTACCGCAGCAGAAAGTCCC
GCATCACGGGAGGCATCTTCTCCGTAATCTTCCTGCTGGCCGGCCTGTACTACATGCTCCCGCCGGAAGGAGCAGCCTGG
TTCGGCCGCGGTTCCGCCCCCGGGGCGGCGGAGTCCGCCGCCGCAGCACCCTCCCTTCAGGAGGAAGGAAACATCTGGAT
ACCCTGGAGCCCGGAAGCCATGCAGGCCGCCCTGGACGGAGGGAAACCCGTTTATGTGGACTTCACGGCCCGCTGGTGCT
CCACCTGCCAGGTCAACAAGGCCTCCTATACGGATGAAGTGCTGGCCGCTTTCAAAAAATATGGCATCGTCATGATGAAA
GCGGACAAGACCCGCACGAACCCCGCCATTGACCAGGAACTTAAAAACCTGGGGCGCACGGCCGTTCCCGTCAATGCCCT
GTATCTTCCCGGCAGAAAACCAGCCGTCACCAGGGAACTCCTGTCCCCGGCCTACCTGCTGGAATTCCTGGAAAAGGAAA
TGGAACGCTAG

Upstream 100 bases:

>100_bases
GGAGGCCGCCCTCGTACGTCGTTTTAGTTTTTACCATGGCCTTATTTTATACAAGGCTCCCCGCCATGCAACACACAAAC
ATTGAATCCCCCCGTTCTTT

Downstream 100 bases:

>100_bases
GACGTCTTGTCATGCGGGCGGCAATCCGCCGCCCTCCCTCCAGGCCATGCCGGGCAGCAGGAAAACGGGGAAAGCTTACC
CTTCCCCGTTCAACAGCGGC

Product: Thiol:disulfide interchange protein-like protein

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 776; Mature: 776

Protein sequence:

>776_residues
MVTAFAMRNFLKAAVGCLGMIAGCFSTGEAQDFGGMSFGEAGNFGPPQTSGSSKATVTSYGEASFVIVTELALPDHWHVY
YKNPGTVGLPMEAALQPVPGFRVEGPFWQIPELEKGLVDFYGYSGKAKMAFRVTPEKDAPPEATFITTMTWQMCAEQCAA
PETKNFSVTLKRGDGQTAPDAAELTGNMAGLAAPDWAEGLKARISQEGKTVTLHLRTNGRPVPQDSVYFFCNQGEINPTT
PQIFKKLDDSNYELSMQFNDTTDGLYPNNLPDADRGKPLTSLSGILRAGREGIIITADDRPFSGESQSTAAGTESAPEPS
ASIPAPPLMGLGEIMFFMFIGGIILNVMPCVFPVIGLKIMGFVQLGGGERKKVLAHSLTFVLGILISFWLITAILIALKA
NMFDWSAPAGPGVFSGDFWLGRGAEGVVNWAFWFENPWVNFCLLGLMLAMGLSMFGVFEIGVKATTMGNDLQHRKGYAGS
FWSGALATVISTPCSAPFLGQAIGAAMLQPPLGIVLCLTMMGLGMSLPYIILGAFPVLTRYLPKPGAWMESFKQSMSFLM
FGTAAYFLWIYMAFFDAENHPQDILFLFFGLVLFSMAFWVYGRWCPMYRSRKSRITGGIFSVIFLLAGLYYMLPPEGAAW
FGRGSAPGAAESAAAAPSLQEEGNIWIPWSPEAMQAALDGGKPVYVDFTARWCSTCQVNKASYTDEVLAAFKKYGIVMMK
ADKTRTNPAIDQELKNLGRTAVPVNALYLPGRKPAVTRELLSPAYLLEFLEKEMER

Sequences:

>Translated_776_residues
MVTAFAMRNFLKAAVGCLGMIAGCFSTGEAQDFGGMSFGEAGNFGPPQTSGSSKATVTSYGEASFVIVTELALPDHWHVY
YKNPGTVGLPMEAALQPVPGFRVEGPFWQIPELEKGLVDFYGYSGKAKMAFRVTPEKDAPPEATFITTMTWQMCAEQCAA
PETKNFSVTLKRGDGQTAPDAAELTGNMAGLAAPDWAEGLKARISQEGKTVTLHLRTNGRPVPQDSVYFFCNQGEINPTT
PQIFKKLDDSNYELSMQFNDTTDGLYPNNLPDADRGKPLTSLSGILRAGREGIIITADDRPFSGESQSTAAGTESAPEPS
ASIPAPPLMGLGEIMFFMFIGGIILNVMPCVFPVIGLKIMGFVQLGGGERKKVLAHSLTFVLGILISFWLITAILIALKA
NMFDWSAPAGPGVFSGDFWLGRGAEGVVNWAFWFENPWVNFCLLGLMLAMGLSMFGVFEIGVKATTMGNDLQHRKGYAGS
FWSGALATVISTPCSAPFLGQAIGAAMLQPPLGIVLCLTMMGLGMSLPYIILGAFPVLTRYLPKPGAWMESFKQSMSFLM
FGTAAYFLWIYMAFFDAENHPQDILFLFFGLVLFSMAFWVYGRWCPMYRSRKSRITGGIFSVIFLLAGLYYMLPPEGAAW
FGRGSAPGAAESAAAAPSLQEEGNIWIPWSPEAMQAALDGGKPVYVDFTARWCSTCQVNKASYTDEVLAAFKKYGIVMMK
ADKTRTNPAIDQELKNLGRTAVPVNALYLPGRKPAVTRELLSPAYLLEFLEKEMER
>Mature_776_residues
MVTAFAMRNFLKAAVGCLGMIAGCFSTGEAQDFGGMSFGEAGNFGPPQTSGSSKATVTSYGEASFVIVTELALPDHWHVY
YKNPGTVGLPMEAALQPVPGFRVEGPFWQIPELEKGLVDFYGYSGKAKMAFRVTPEKDAPPEATFITTMTWQMCAEQCAA
PETKNFSVTLKRGDGQTAPDAAELTGNMAGLAAPDWAEGLKARISQEGKTVTLHLRTNGRPVPQDSVYFFCNQGEINPTT
PQIFKKLDDSNYELSMQFNDTTDGLYPNNLPDADRGKPLTSLSGILRAGREGIIITADDRPFSGESQSTAAGTESAPEPS
ASIPAPPLMGLGEIMFFMFIGGIILNVMPCVFPVIGLKIMGFVQLGGGERKKVLAHSLTFVLGILISFWLITAILIALKA
NMFDWSAPAGPGVFSGDFWLGRGAEGVVNWAFWFENPWVNFCLLGLMLAMGLSMFGVFEIGVKATTMGNDLQHRKGYAGS
FWSGALATVISTPCSAPFLGQAIGAAMLQPPLGIVLCLTMMGLGMSLPYIILGAFPVLTRYLPKPGAWMESFKQSMSFLM
FGTAAYFLWIYMAFFDAENHPQDILFLFFGLVLFSMAFWVYGRWCPMYRSRKSRITGGIFSVIFLLAGLYYMLPPEGAAW
FGRGSAPGAAESAAAAPSLQEEGNIWIPWSPEAMQAALDGGKPVYVDFTARWCSTCQVNKASYTDEVLAAFKKYGIVMMK
ADKTRTNPAIDQELKNLGRTAVPVNALYLPGRKPAVTRELLSPAYLLEFLEKEMER

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=463, Percent_Identity=23.9740820734341, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 84331; Mature: 84331

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTAFAMRNFLKAAVGCLGMIAGCFSTGEAQDFGGMSFGEAGNFGPPQTSGSSKATVTSY
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEC
GEASFVIVTELALPDHWHVYYKNPGTVGLPMEAALQPVPGFRVEGPFWQIPELEKGLVDF
CCEEEEEEEEECCCCCEEEEECCCCCCCCCHHHHCCCCCCCEECCCCCCCCCHHHHHHHH
YGYSGKAKMAFRVTPEKDAPPEATFITTMTWQMCAEQCAAPETKNFSVTLKRGDGQTAPD
HCCCCCEEEEEEECCCCCCCCCCEEEEHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCC
AAELTGNMAGLAAPDWAEGLKARISQEGKTVTLHLRTNGRPVPQDSVYFFCNQGEINPTT
HHHHCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEEECCCCCCCCC
PQIFKKLDDSNYELSMQFNDTTDGLYPNNLPDADRGKPLTSLSGILRAGREGIIITADDR
HHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCC
PFSGESQSTAAGTESAPEPSASIPAPPLMGLGEIMFFMFIGGIILNVMPCVFPVIGLKIM
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFVQLGGGERKKVLAHSLTFVLGILISFWLITAILIALKANMFDWSAPAGPGVFSGDFWL
HEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEE
GRGAEGVVNWAFWFENPWVNFCLLGLMLAMGLSMFGVFEIGVKATTMGNDLQHRKGYAGS
CCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCHHHHCCCCCC
FWSGALATVISTPCSAPFLGQAIGAAMLQPPLGIVLCLTMMGLGMSLPYIILGAFPVLTR
HHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
YLPKPGAWMESFKQSMSFLMFGTAAYFLWIYMAFFDAENHPQDILFLFFGLVLFSMAFWV
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
YGRWCPMYRSRKSRITGGIFSVIFLLAGLYYMLPPEGAAWFGRGSAPGAAESAAAAPSLQ
HHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCCHH
EEGNIWIPWSPEAMQAALDGGKPVYVDFTARWCSTCQVNKASYTDEVLAAFKKYGIVMMK
HCCCEEECCCHHHHHHHHCCCCEEEEEECHHHHCCCCCCCCCHHHHHHHHHHHCCEEEEE
ADKTRTNPAIDQELKNLGRTAVPVNALYLPGRKPAVTRELLSPAYLLEFLEKEMER
CCCCCCCCHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHCHHHHHHHHHHHHCC
>Mature Secondary Structure
MVTAFAMRNFLKAAVGCLGMIAGCFSTGEAQDFGGMSFGEAGNFGPPQTSGSSKATVTSY
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEC
GEASFVIVTELALPDHWHVYYKNPGTVGLPMEAALQPVPGFRVEGPFWQIPELEKGLVDF
CCEEEEEEEEECCCCCEEEEECCCCCCCCCHHHHCCCCCCCEECCCCCCCCCHHHHHHHH
YGYSGKAKMAFRVTPEKDAPPEATFITTMTWQMCAEQCAAPETKNFSVTLKRGDGQTAPD
HCCCCCEEEEEEECCCCCCCCCCEEEEHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCC
AAELTGNMAGLAAPDWAEGLKARISQEGKTVTLHLRTNGRPVPQDSVYFFCNQGEINPTT
HHHHCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEEECCCCCCCCC
PQIFKKLDDSNYELSMQFNDTTDGLYPNNLPDADRGKPLTSLSGILRAGREGIIITADDR
HHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCC
PFSGESQSTAAGTESAPEPSASIPAPPLMGLGEIMFFMFIGGIILNVMPCVFPVIGLKIM
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFVQLGGGERKKVLAHSLTFVLGILISFWLITAILIALKANMFDWSAPAGPGVFSGDFWL
HEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEE
GRGAEGVVNWAFWFENPWVNFCLLGLMLAMGLSMFGVFEIGVKATTMGNDLQHRKGYAGS
CCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCHHHHCCCCCC
FWSGALATVISTPCSAPFLGQAIGAAMLQPPLGIVLCLTMMGLGMSLPYIILGAFPVLTR
HHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
YLPKPGAWMESFKQSMSFLMFGTAAYFLWIYMAFFDAENHPQDILFLFFGLVLFSMAFWV
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
YGRWCPMYRSRKSRITGGIFSVIFLLAGLYYMLPPEGAAWFGRGSAPGAAESAAAAPSLQ
HHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCCHH
EEGNIWIPWSPEAMQAALDGGKPVYVDFTARWCSTCQVNKASYTDEVLAAFKKYGIVMMK
HCCCEEECCCHHHHHHHHCCCCEEEEEECHHHHCCCCCCCCCHHHHHHHHHHHCCEEEEE
ADKTRTNPAIDQELKNLGRTAVPVNALYLPGRKPAVTRELLSPAYLLEFLEKEMER
CCCCCCCCHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]