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The map label for this gene is ywlC [H]

Identifier: 187734781

GI number: 187734781

Start: 331372

End: 332418

Strand: Reverse

Name: ywlC [H]

Synonym: Amuc_0269

Alternate gene names: 187734781

Gene position: 332418-331372 (Counterclockwise)

Preceding gene: 187734783

Following gene: 187734780

Centisome position: 12.48

GC content: 59.6

Gene sequence:

>1047_bases
ATGCAAACCGAATTGTTCGAGGTAGATCCCCTGTCAGACAACCGCAAACTGTATGCCCGTGCGGCGGAAGCTCTGGGTGC
GGGCGCGCTGGTAGGGATTCCCACGGAGACTGTATACGGCCTGGGGGCGGATGCCTTGAACCCGGAAGCGGTAGCAAGGA
TTTTTGAAGCCAAGGGAAGGCCTTCTTTTGATCCGCTGATTATTCATGTGCATCATGGGAGTGAGGTGGAAAAATATACC
GCCGTTCCGGAGGGGCTGAAAGATCTGGTGCATACGCTTGCCTCCAGATTCTGGCCGGGGCCGCTGACCTTGGTGTTGCC
AAAGGCGGATATCATTCCGGATATTGTAACCAGCGGCCTTCCTACGGTGGCCGTTCGCGTAAGCGCTCATCCTGCCATGC
GGGGGGTGGCGAAAGCGCTGGGGCGTCCTATAGCTGCGCCCAGCGCCAACCGCTTCGGCCATATCAGCCCTACTTCCGCC
TCTGCCGTACAGAAGGAATTGGGGGGCAGTATTGAAATGATTCTGGATGCCGGAGCCTGTTCCGAGGGGCTGGAAAGCAC
GATTGTGCGCCCTGTGCTTGACGAGAAGGGCAAGCCCTCTCTGGAATTGCTGCGTGAGGGGCCGGTGACCCGGGAACAAT
TTCGCAACCTGGTCAAGGTGGTGCGCCGCAAGCCTTCCTGCCGTCCTGTTTCGGAAGAATCTCCGGCGGATGCGCCGGGG
CAGCTCACCAGCCATTACGCCCCGCGCAAACCTATGCTGTTGCTGGAACCGGGGGAAAATTTTGCCCCGGTGGAGGGGGT
GAAGTACGGCCTGCTTTCCTATGAAGGAACGTCCGCTCTTGCCCGGGAAGGGGACTGGGCGGAAGTGGTAGCCATGAGTC
CCGGCAGCGGGCGGCTGGCAGAAGCTGCCGTGCGCCTGTTTGCCCTGATGAGACAGATGGATGAAAATGAAGCTATTGAC
GTCATTGTGGCGGAATCCGTTCCGGAATCCGGCCTGGGCCGCGCTATTATGGATCGCCTGCGACGCGCTTCAGCCGTCAG
GGAATAA

Upstream 100 bases:

>100_bases
TGAGGCCGCAGGACGTGCTCTTATTCATTTGTCTGTTTTCTCCTTTCAGGGGAAGGAGGTCTTGCTTGACGCAGGAGCTT
CTTCAGGCAAGGATAAAGCC

Downstream 100 bases:

>100_bases
CTTGCCCACGGTTTGCAAAACATGTTAAAGTCATTGCAGATTCCTTTTTGATTTTATGGCCGCTACGTTATTTGAAAAAA
TCTGTTCAGGGGAAATCCCC

Product: Sua5/YciO/YrdC/YwlC family protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MQTELFEVDPLSDNRKLYARAAEALGAGALVGIPTETVYGLGADALNPEAVARIFEAKGRPSFDPLIIHVHHGSEVEKYT
AVPEGLKDLVHTLASRFWPGPLTLVLPKADIIPDIVTSGLPTVAVRVSAHPAMRGVAKALGRPIAAPSANRFGHISPTSA
SAVQKELGGSIEMILDAGACSEGLESTIVRPVLDEKGKPSLELLREGPVTREQFRNLVKVVRRKPSCRPVSEESPADAPG
QLTSHYAPRKPMLLLEPGENFAPVEGVKYGLLSYEGTSALAREGDWAEVVAMSPGSGRLAEAAVRLFALMRQMDENEAID
VIVAESVPESGLGRAIMDRLRRASAVRE

Sequences:

>Translated_348_residues
MQTELFEVDPLSDNRKLYARAAEALGAGALVGIPTETVYGLGADALNPEAVARIFEAKGRPSFDPLIIHVHHGSEVEKYT
AVPEGLKDLVHTLASRFWPGPLTLVLPKADIIPDIVTSGLPTVAVRVSAHPAMRGVAKALGRPIAAPSANRFGHISPTSA
SAVQKELGGSIEMILDAGACSEGLESTIVRPVLDEKGKPSLELLREGPVTREQFRNLVKVVRRKPSCRPVSEESPADAPG
QLTSHYAPRKPMLLLEPGENFAPVEGVKYGLLSYEGTSALAREGDWAEVVAMSPGSGRLAEAAVRLFALMRQMDENEAID
VIVAESVPESGLGRAIMDRLRRASAVRE
>Mature_348_residues
MQTELFEVDPLSDNRKLYARAAEALGAGALVGIPTETVYGLGADALNPEAVARIFEAKGRPSFDPLIIHVHHGSEVEKYT
AVPEGLKDLVHTLASRFWPGPLTLVLPKADIIPDIVTSGLPTVAVRVSAHPAMRGVAKALGRPIAAPSANRFGHISPTSA
SAVQKELGGSIEMILDAGACSEGLESTIVRPVLDEKGKPSLELLREGPVTREQFRNLVKVVRRKPSCRPVSEESPADAPG
QLTSHYAPRKPMLLLEPGENFAPVEGVKYGLLSYEGTSALAREGDWAEVVAMSPGSGRLAEAAVRLFALMRQMDENEAID
VIVAESVPESGLGRAIMDRLRRASAVRE

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Homo sapiens, GI58761510, Length=180, Percent_Identity=32.7777777777778, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI2367210, Length=161, Percent_Identity=29.8136645962733, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17537239, Length=192, Percent_Identity=30.2083333333333, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321269, Length=368, Percent_Identity=34.2391304347826, Blast_Score=159, Evalue=9e-40,
Organism=Drosophila melanogaster, GI78707274, Length=189, Percent_Identity=27.5132275132275, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 37195; Mature: 37195

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTELFEVDPLSDNRKLYARAAEALGAGALVGIPTETVYGLGADALNPEAVARIFEAKGR
CCCCEEECCCCCCCHHHHHHHHHHHCCCCEEECCCHHHHCCCCCCCCHHHHHHHHHHCCC
PSFDPLIIHVHHGSEVEKYTAVPEGLKDLVHTLASRFWPGPLTLVLPKADIIPDIVTSGL
CCCCCEEEEEECCCCHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHCCC
PTVAVRVSAHPAMRGVAKALGRPIAAPSANRFGHISPTSASAVQKELGGSIEMILDAGAC
CEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCC
SEGLESTIVRPVLDEKGKPSLELLREGPVTREQFRNLVKVVRRKPSCRPVSEESPADAPG
HHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
QLTSHYAPRKPMLLLEPGENFAPVEGVKYGLLSYEGTSALAREGDWAEVVAMSPGSGRLA
HHHHCCCCCCCEEEECCCCCCCCCCCHHHHHEEECCCHHHHCCCCCEEEEEECCCCCHHH
EAAVRLFALMRQMDENEAIDVIVAESVPESGLGRAIMDRLRRASAVRE
HHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQTELFEVDPLSDNRKLYARAAEALGAGALVGIPTETVYGLGADALNPEAVARIFEAKGR
CCCCEEECCCCCCCHHHHHHHHHHHCCCCEEECCCHHHHCCCCCCCCHHHHHHHHHHCCC
PSFDPLIIHVHHGSEVEKYTAVPEGLKDLVHTLASRFWPGPLTLVLPKADIIPDIVTSGL
CCCCCEEEEEECCCCHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHCCC
PTVAVRVSAHPAMRGVAKALGRPIAAPSANRFGHISPTSASAVQKELGGSIEMILDAGAC
CEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCC
SEGLESTIVRPVLDEKGKPSLELLREGPVTREQFRNLVKVVRRKPSCRPVSEESPADAPG
HHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
QLTSHYAPRKPMLLLEPGENFAPVEGVKYGLLSYEGTSALAREGDWAEVVAMSPGSGRLA
HHHHCCCCCCCEEEECCCCCCCCCCCHHHHHEEECCCHHHHCCCCCEEEEEECCCCCHHH
EAAVRLFALMRQMDENEAIDVIVAESVPESGLGRAIMDRLRRASAVRE
HHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]