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The map label for this gene is yqjC [H]

Identifier: 187734713

GI number: 187734713

Start: 250061

End: 250483

Strand: Direct

Name: yqjC [H]

Synonym: Amuc_0200

Alternate gene names: 187734713

Gene position: 250061-250483 (Clockwise)

Preceding gene: 187734710

Following gene: 187734714

Centisome position: 9.39

GC content: 58.16

Gene sequence:

>423_bases
ATGATTCAGCAAATTGACCATATCGGCATCGCCGTCAAGAGCCTTGACGCCACCGTCCCCTATTACCGCGATGCGCTCGG
GCTCGGAGAGCCCCACATTGAGGAAGTTCCCACTCAAAAGGTCCGCGTCGCCATGTTTGACGTTGCCGGAGTCCACATCG
AACTGCTCGAACCCACCTCTCCGGAAAGCGCTATCGCCAAGGCTATTGAGAAAAAAGGGGAAGGCATCCACCACATCGCT
TTCAAGACCAATGACATCGCCGGAAATATCTCCCAGGCCAAGGAAGCAGGCCTTACCGTGCTGAACGACCCGCCCGTCCC
CGGCGCTCACAACACGCAGGTCACCTTCCTGCATCCCAAGTGCACCTTCGGCGTCCTGACCGAATTCTGCCAGCACCCCG
GCAGCTGCGAATGCGGCAAGTAA

Upstream 100 bases:

>100_bases
TTTTTCCGCTTTTCGCTTCACATCCTAAAAAAATACGCTTTAATAACTCTTGATGTATTGCAGGCCTCCCCCCTGCATTC
CCTATAACCATCACACGCAT

Downstream 100 bases:

>100_bases
CATTCTCCCTATTCACCATACCACTAGACCAATGGCTATTGATCCCAAATTGATTGACGATCTGAACAGCCGCCGCAAGA
AGGTCATCCTCAGCGGCGGT

Product: methylmalonyl-CoA epimerase

Products: glutathione; methylglyoxal

Alternate protein names: NA

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MIQQIDHIGIAVKSLDATVPYYRDALGLGEPHIEEVPTQKVRVAMFDVAGVHIELLEPTSPESAIAKAIEKKGEGIHHIA
FKTNDIAGNISQAKEAGLTVLNDPPVPGAHNTQVTFLHPKCTFGVLTEFCQHPGSCECGK

Sequences:

>Translated_140_residues
MIQQIDHIGIAVKSLDATVPYYRDALGLGEPHIEEVPTQKVRVAMFDVAGVHIELLEPTSPESAIAKAIEKKGEGIHHIA
FKTNDIAGNISQAKEAGLTVLNDPPVPGAHNTQVTFLHPKCTFGVLTEFCQHPGSCECGK
>Mature_140_residues
MIQQIDHIGIAVKSLDATVPYYRDALGLGEPHIEEVPTQKVRVAMFDVAGVHIELLEPTSPESAIAKAIEKKGEGIHHIA
FKTNDIAGNISQAKEAGLTVLNDPPVPGAHNTQVTFLHPKCTFGVLTEFCQHPGSCECGK

Specific function: Unknown

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyoxalase I family [H]

Homologues:

Organism=Homo sapiens, GI188035928, Length=129, Percent_Identity=31.7829457364341, Blast_Score=69, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17506387, Length=134, Percent_Identity=34.3283582089552, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360
- InterPro:   IPR018146
- InterPro:   IPR017515 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: 4.4.1.5

Molecular weight: Translated: 15046; Mature: 15046

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQQIDHIGIAVKSLDATVPYYRDALGLGEPHIEEVPTQKVRVAMFDVAGVHIELLEPTS
CCCCCCHHHEEEECCCCCCCHHHHHHCCCCCCHHHCCCCCEEEEEEEECCEEEEEECCCC
PESAIAKAIEKKGEGIHHIAFKTNDIAGNISQAKEAGLTVLNDPPVPGAHNTQVTFLHPK
CHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHCCCEEECCCCCCCCCCCEEEEECCC
CTFGVLTEFCQHPGSCECGK
CCHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MIQQIDHIGIAVKSLDATVPYYRDALGLGEPHIEEVPTQKVRVAMFDVAGVHIELLEPTS
CCCCCCHHHEEEECCCCCCCHHHHHHCCCCCCHHHCCCCCEEEEEEEECCEEEEEECCCC
PESAIAKAIEKKGEGIHHIAFKTNDIAGNISQAKEAGLTVLNDPPVPGAHNTQVTFLHPK
CHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHCCCEEECCCCCCCCCCCEEEEECCC
CTFGVLTEFCQHPGSCECGK
CCHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-S-lactoylglutathione

Specific reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]