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The map label for this gene is namA [H]

Identifier: 186477804

GI number: 186477804

Start: 3436052

End: 3437182

Strand: Reverse

Name: namA [H]

Synonym: Bphy_3060

Alternate gene names: 186477804

Gene position: 3437182-3436052 (Counterclockwise)

Preceding gene: 186477805

Following gene: 186477803

Centisome position: 98.79

GC content: 64.72

Gene sequence:

>1131_bases
ATGGGCAACACTACAACCATGAGCGCACTTTTCACTCCGCTCACGCTGCGTAGCGTGACGCTGCCAAACCGCATCGTCGT
GTCGCCGATGTGTCAGTACTCCGCCGAACGCGGCGAAGCGACCGCATGGCACATGATCCACCTGGGCCATCTCGCTCTGT
CGGGCGCAGGCATGCTGTGCATCGAGGCGACGGCCGTGGAACCCGATGGCCGCATCACGCCCGCCGATCTCGGCTTGTGG
GACGATGTGACGGAAGAGGCGCTGAAACCGGTGATCGCCGCAATCCGCAAGCATTCGAAAGTGCACATCGCGATGCAGCT
GTCGCACGCGGGGCGTAAGGCGTCGAGCAATGTGCCGTGGAAAGGCGGTCAACTGATTTCCGTCGCCAACGGCGGCTGGC
TGCCACACGCGCCGTCCGCCATTCCGCACAAGGCGGGTGAAGAGGCACCGCTCGCGCTCGACAGTGCAGGTCTCAACCGA
ATTCGCGAAGCGTTCGCAGCGACGGCGCGCCGCGCCGCGCGCCTCGGCATCGATGCGCTCGAAGTGCATGCCGCGCACGG
CTATCTGCTGCACCAGTTTCTGTCGCCGCTCGCGAACCAGCGTACCGACGAATATGGCGGCTCGCGCGAGAACCGCATGC
GTTTCCCGCTGGAAATCTTCGATATCGTGCGTGCGGCATTTCCCGTCGACAAGCCTGTCGGCGTGCGCGTGTCGGCGGTC
GACTGGGTCGAAGGCGGCCTTACGATCGAAGACACGATCGCCTTCGTGCAAGAGCTGAAGAAGCGCGGTTGCGACTGGGT
GGATGTATCGTCGGGCGGTGTCTCGCCGTTGCAGAAGATTCCCGTCGAGCCGGGCTATCAAGTGCCCTTCGCGAAGGCGG
TCAGGAAGGCGACGGGCTTGACGACGGTGGCCGTCGGTCTGATTACCGACCCGGAGCATGCAAACCAGCTGATCGAAGAG
GGCGATGCCGATCTCGTCGCGATGGCTCGCGCGATGCTTTACGATCCGCGCTGGCCGTGGCATGCGGCCGCGAAGCTCGG
CGCAACCGTCGAGGCGCCGCCGCAATACTGGCGCTCGCAGCCGCGCGAGCAGAAGGCGCTGTTCGGCGACATTTCGTTCG
GTCAGCGCTGA

Upstream 100 bases:

>100_bases
AAAGCTGATTCGCGCCGCTGAAAAGCGGTCATGACGCGGCGCGCCAGGCCGTCTGCAGCAAATCGGACCGGGTGCTATGC
TCGATCGCTCTTGAGTTTCG

Downstream 100 bases:

>100_bases
GCTGGGCGTTCGGGTTGTCGAGGTGGATCGCGGATTGCGTGCAATGCGAGGCGGATCTGCACGTCTGACGGTTGAACGAA
TCCACATCATCCGTGTACGA

Product: NADH:flavin oxidoreductase/NADH oxidase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MGNTTTMSALFTPLTLRSVTLPNRIVVSPMCQYSAERGEATAWHMIHLGHLALSGAGMLCIEATAVEPDGRITPADLGLW
DDVTEEALKPVIAAIRKHSKVHIAMQLSHAGRKASSNVPWKGGQLISVANGGWLPHAPSAIPHKAGEEAPLALDSAGLNR
IREAFAATARRAARLGIDALEVHAAHGYLLHQFLSPLANQRTDEYGGSRENRMRFPLEIFDIVRAAFPVDKPVGVRVSAV
DWVEGGLTIEDTIAFVQELKKRGCDWVDVSSGGVSPLQKIPVEPGYQVPFAKAVRKATGLTTVAVGLITDPEHANQLIEE
GDADLVAMARAMLYDPRWPWHAAAKLGATVEAPPQYWRSQPREQKALFGDISFGQR

Sequences:

>Translated_376_residues
MGNTTTMSALFTPLTLRSVTLPNRIVVSPMCQYSAERGEATAWHMIHLGHLALSGAGMLCIEATAVEPDGRITPADLGLW
DDVTEEALKPVIAAIRKHSKVHIAMQLSHAGRKASSNVPWKGGQLISVANGGWLPHAPSAIPHKAGEEAPLALDSAGLNR
IREAFAATARRAARLGIDALEVHAAHGYLLHQFLSPLANQRTDEYGGSRENRMRFPLEIFDIVRAAFPVDKPVGVRVSAV
DWVEGGLTIEDTIAFVQELKKRGCDWVDVSSGGVSPLQKIPVEPGYQVPFAKAVRKATGLTTVAVGLITDPEHANQLIEE
GDADLVAMARAMLYDPRWPWHAAAKLGATVEAPPQYWRSQPREQKALFGDISFGQR
>Mature_375_residues
GNTTTMSALFTPLTLRSVTLPNRIVVSPMCQYSAERGEATAWHMIHLGHLALSGAGMLCIEATAVEPDGRITPADLGLWD
DVTEEALKPVIAAIRKHSKVHIAMQLSHAGRKASSNVPWKGGQLISVANGGWLPHAPSAIPHKAGEEAPLALDSAGLNRI
REAFAATARRAARLGIDALEVHAAHGYLLHQFLSPLANQRTDEYGGSRENRMRFPLEIFDIVRAAFPVDKPVGVRVSAVD
WVEGGLTIEDTIAFVQELKKRGCDWVDVSSGGVSPLQKIPVEPGYQVPFAKAVRKATGLTTVAVGLITDPEHANQLIEEG
DADLVAMARAMLYDPRWPWHAAAKLGATVEAPPQYWRSQPREQKALFGDISFGQR

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789463, Length=354, Percent_Identity=29.9435028248588, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1787939, Length=369, Percent_Identity=29.810298102981, Blast_Score=113, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI72001454, Length=266, Percent_Identity=30.0751879699248, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17564188, Length=228, Percent_Identity=31.140350877193, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17559804, Length=193, Percent_Identity=33.6787564766839, Blast_Score=111, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17559802, Length=247, Percent_Identity=30.3643724696356, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17540738, Length=203, Percent_Identity=32.512315270936, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17565138, Length=272, Percent_Identity=27.2058823529412, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17566914, Length=155, Percent_Identity=33.5483870967742, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6325086, Length=235, Percent_Identity=28.0851063829787, Blast_Score=87, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6321973, Length=234, Percent_Identity=27.3504273504274, Blast_Score=83, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 40709; Mature: 40578

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNTTTMSALFTPLTLRSVTLPNRIVVSPMCQYSAERGEATAWHMIHLGHLALSGAGMLC
CCCCHHHHHHHHHHHHEEECCCCEEEECHHHHHHHCCCCCEEEHHEEHHHHHHCCCCEEE
IEATAVEPDGRITPADLGLWDDVTEEALKPVIAAIRKHSKVHIAMQLSHAGRKASSNVPW
EEEEEECCCCCCCHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCC
KGGQLISVANGGWLPHAPSAIPHKAGEEAPLALDSAGLNRIREAFAATARRAARLGIDAL
CCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHCCHHH
EVHAAHGYLLHQFLSPLANQRTDEYGGSRENRMRFPLEIFDIVRAAFPVDKPVGVRVSAV
HHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCEECCHHHHHHHHHHCCCCCCCCCEEEEE
DWVEGGLTIEDTIAFVQELKKRGCDWVDVSSGGVSPLQKIPVEPGYQVPFAKAVRKATGL
HHHCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHCCCCCCCCCCHHHHHHHHCCC
TTVAVGLITDPEHANQLIEEGDADLVAMARAMLYDPRWPWHAAAKLGATVEAPPQYWRSQ
EEEEEEEEECHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHHCC
PREQKALFGDISFGQR
CCHHHHHCCCCCCCCC
>Mature Secondary Structure 
GNTTTMSALFTPLTLRSVTLPNRIVVSPMCQYSAERGEATAWHMIHLGHLALSGAGMLC
CCCHHHHHHHHHHHHEEECCCCEEEECHHHHHHHCCCCCEEEHHEEHHHHHHCCCCEEE
IEATAVEPDGRITPADLGLWDDVTEEALKPVIAAIRKHSKVHIAMQLSHAGRKASSNVPW
EEEEEECCCCCCCHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCC
KGGQLISVANGGWLPHAPSAIPHKAGEEAPLALDSAGLNRIREAFAATARRAARLGIDAL
CCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHCCHHH
EVHAAHGYLLHQFLSPLANQRTDEYGGSRENRMRFPLEIFDIVRAAFPVDKPVGVRVSAV
HHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCEECCHHHHHHHHHHCCCCCCCCCEEEEE
DWVEGGLTIEDTIAFVQELKKRGCDWVDVSSGGVSPLQKIPVEPGYQVPFAKAVRKATGL
HHHCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHCCCCCCCCCCHHHHHHHHCCC
TTVAVGLITDPEHANQLIEEGDADLVAMARAMLYDPRWPWHAAAKLGATVEAPPQYWRSQ
EEEEEEEEECHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHHCC
PREQKALFGDISFGQR
CCHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA