Click here to switch to the map view.

The map label for this gene is 186477754

Identifier: 186477754

GI number: 186477754

Start: 3375495

End: 3376547

Strand: Reverse

Name: 186477754

Synonym: Bphy_3008

Alternate gene names: NA

Gene position: 3376547-3375495 (Counterclockwise)

Preceding gene: 186477755

Following gene: 186477753

Centisome position: 97.05

GC content: 63.44

Gene sequence:

>1053_bases
ATGAAAGAAATCAGAATCGCCAACCGGACCGTAGGTCCAGGCAGCCAGCCATTCGTGATCGCGGAGATGTCCGGCAATCA
CAACCAGTCGCTGGAACGGGCGCTGGACATCGTCGAGGCGGCGGCAGCCAGCGGCGCGCATGCGCTGAAGCTGCAGACCT
ATACGCCCGACACGATGACGCTCGATCTCAACGAAGGCGAGTTCCATATCGGCGAAGAAAACAGCCTGTGGGCGGGCAAA
TCGCTTTACGCGCTGTATCAGGAAGCTTATACGCCGTGGGAATGGCACAAGCCGCTCTTCGACCATGCGAAGCGGCTCGG
CATGCTCGCGTTCTCGACGCCGTTCGACGAAACGGCTGTCGATTTTCTCGAAACGCTCGATGTGCCCGCCTACAAGATCG
CCAGCTTCGAAAACACCGATTTGCCGCTGATCCGGCGCGTCGCCGCGACGGGCAAACCGATGATCATCTCCACGGGCATG
GCGTCCGTCGCGGAACTCGATGAGGCCGTGCGCGCCGCCCGCGGGGCCGGTTGCGAGGATCTGATCCTGCTCAAATGCAC
GAGCTCGTATCCGGCGACGCCCGAACACAGCAACATTCGCACGATTCCGCATATGCGCGATCTGTTCGGCTGCCAGGTCG
GCCTGTCGGATCACACGATGGGCGTGGGTGCCGCTGTCGCCGCGATCGCACTCGGCGCGACGGTCGTCGAAAAGCACTTC
ACGCTGCGCCGCGCCGATGGCGGCGTCGACTCCGCGTTCTCGCTGGAGCCTGAAGAAATGCGCGCGCTGGTGACGGAAAC
CGAGCGCGCATGGCAGGCGCTCGGCCAACCAGCCTATGGGACCAACGAACAGGAGCGCAAGTCGATGGTCTTCCGCCGCT
CGTTGTATGTGGTCAAGGACGTCGGCGCGGGCGAAACGCTGACGCGCGACCACATCCGCGCGATCCGGCCCGGACTCGGC
ATGGCGCCGAAGCATCTCGAGACGGTCATCGGCATGACGGCGCGCGCACCGATCAAACGCGGCACGCCGCTTAACTGGGA
CGTTCTGAAATGA

Upstream 100 bases:

>100_bases
CGCAATCGAACGGCTGACAAATAGACGCGCAAAACGATCCATATCAGGGACCCGCGAGTCCCAATAACGGAAGACGCGGG
ACGGCGTGAGGAAACAACCG

Downstream 100 bases:

>100_bases
GTGCACAACCTGAAAACTTCGCTGGATCGCAGGGGCGCAAGGATCTGATCCAGTGGAAAACCGATGCCTGGAAAGATCCC
GGCATGGTGAACTGGTATTC

Product: N-acylneuraminate-9-phosphate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MKEIRIANRTVGPGSQPFVIAEMSGNHNQSLERALDIVEAAAASGAHALKLQTYTPDTMTLDLNEGEFHIGEENSLWAGK
SLYALYQEAYTPWEWHKPLFDHAKRLGMLAFSTPFDETAVDFLETLDVPAYKIASFENTDLPLIRRVAATGKPMIISTGM
ASVAELDEAVRAARGAGCEDLILLKCTSSYPATPEHSNIRTIPHMRDLFGCQVGLSDHTMGVGAAVAAIALGATVVEKHF
TLRRADGGVDSAFSLEPEEMRALVTETERAWQALGQPAYGTNEQERKSMVFRRSLYVVKDVGAGETLTRDHIRAIRPGLG
MAPKHLETVIGMTARAPIKRGTPLNWDVLK

Sequences:

>Translated_350_residues
MKEIRIANRTVGPGSQPFVIAEMSGNHNQSLERALDIVEAAAASGAHALKLQTYTPDTMTLDLNEGEFHIGEENSLWAGK
SLYALYQEAYTPWEWHKPLFDHAKRLGMLAFSTPFDETAVDFLETLDVPAYKIASFENTDLPLIRRVAATGKPMIISTGM
ASVAELDEAVRAARGAGCEDLILLKCTSSYPATPEHSNIRTIPHMRDLFGCQVGLSDHTMGVGAAVAAIALGATVVEKHF
TLRRADGGVDSAFSLEPEEMRALVTETERAWQALGQPAYGTNEQERKSMVFRRSLYVVKDVGAGETLTRDHIRAIRPGLG
MAPKHLETVIGMTARAPIKRGTPLNWDVLK
>Mature_350_residues
MKEIRIANRTVGPGSQPFVIAEMSGNHNQSLERALDIVEAAAASGAHALKLQTYTPDTMTLDLNEGEFHIGEENSLWAGK
SLYALYQEAYTPWEWHKPLFDHAKRLGMLAFSTPFDETAVDFLETLDVPAYKIASFENTDLPLIRRVAATGKPMIISTGM
ASVAELDEAVRAARGAGCEDLILLKCTSSYPATPEHSNIRTIPHMRDLFGCQVGLSDHTMGVGAAVAAIALGATVVEKHF
TLRRADGGVDSAFSLEPEEMRALVTETERAWQALGQPAYGTNEQERKSMVFRRSLYVVKDVGAGETLTRDHIRAIRPGLG
MAPKHLETVIGMTARAPIKRGTPLNWDVLK

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=290, Percent_Identity=31.0344827586207, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI21357081, Length=254, Percent_Identity=33.4645669291339, Blast_Score=139, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 38272; Mature: 38272

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS50844 AFP_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEIRIANRTVGPGSQPFVIAEMSGNHNQSLERALDIVEAAAASGAHALKLQTYTPDTMT
CCCEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEE
LDLNEGEFHIGEENSLWAGKSLYALYQEAYTPWEWHKPLFDHAKRLGMLAFSTPFDETAV
EECCCCCEEECCCCCCCCCHHHHHHHHHHCCCHHHCCHHHHHHHHHCCEEECCCCCHHHH
DFLETLDVPAYKIASFENTDLPLIRRVAATGKPMIISTGMASVAELDEAVRAARGAGCED
HHHHHCCCCCEEEECCCCCCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHCCCCCE
LILLKCTSSYPATPEHSNIRTIPHMRDLFGCQVGLSDHTMGVGAAVAAIALGATVVEKHF
EEEEEECCCCCCCCCCCCCEECCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
TLRRADGGVDSAFSLEPEEMRALVTETERAWQALGQPAYGTNEQERKSMVFRRSLYVVKD
HEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHEEEEE
VGAGETLTRDHIRAIRPGLGMAPKHLETVIGMTARAPIKRGTPLNWDVLK
CCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKEIRIANRTVGPGSQPFVIAEMSGNHNQSLERALDIVEAAAASGAHALKLQTYTPDTMT
CCCEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEE
LDLNEGEFHIGEENSLWAGKSLYALYQEAYTPWEWHKPLFDHAKRLGMLAFSTPFDETAV
EECCCCCEEECCCCCCCCCHHHHHHHHHHCCCHHHCCHHHHHHHHHCCEEECCCCCHHHH
DFLETLDVPAYKIASFENTDLPLIRRVAATGKPMIISTGMASVAELDEAVRAARGAGCED
HHHHHCCCCCEEEECCCCCCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHCCCCCE
LILLKCTSSYPATPEHSNIRTIPHMRDLFGCQVGLSDHTMGVGAAVAAIALGATVVEKHF
EEEEEECCCCCCCCCCCCCEECCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
TLRRADGGVDSAFSLEPEEMRALVTETERAWQALGQPAYGTNEQERKSMVFRRSLYVVKD
HEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHEEEEE
VGAGETLTRDHIRAIRPGLGMAPKHLETVIGMTARAPIKRGTPLNWDVLK
CCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]