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The map label for this gene is motA [H]

Identifier: 186477723

GI number: 186477723

Start: 3335585

End: 3336445

Strand: Reverse

Name: motA [H]

Synonym: Bphy_2977

Alternate gene names: 186477723

Gene position: 3336445-3335585 (Counterclockwise)

Preceding gene: 186477724

Following gene: 186477722

Centisome position: 95.9

GC content: 60.86

Gene sequence:

>861_bases
GTGCTGATTTTCGTGGGAACACTCGTTACGCTGTTGTCCGTCTTCGGCGGCTATGCGCTGGAGGGCGGCCACCTGGGCGC
GCTCATGCAGCCCGTCGAAGTGCTGATGATCGCAGGAGCGGGCGTCGGCGCATTCATTCTCGGCAACGGGATGAAGACGA
TCAAGGCTACGCTGCGCGTGATTCCGACGCTGTTCAAAGGCGCCAAATACAACAAGGACGTCTACATGGAGCTGATGGCG
CTCCTCTACGTTCTGCTGGCGAAGGCGCGCAAGGAGGGCACGCTCACGCTCGAAGCGGATATCGACGACCCGCAAAAGAG
CCCGATCTTCACGCAATACCCGAAGATTCTCGCGGACCATCACATCGTCGAATTCCTGACGGACTATCTGCGCCTGATGG
TCGGCGGCAACATGAATGCGTTTGAGATCGAAAGCTTGATGGACGAAGAGATCGAAACGCATCACGCCGAAGGCGAAGCG
CCCGCACACGCGCTGATGAAGGTCGGCGACGCGATGCCCGCATTCGGTATCGTCGCGGCCGTGATGGGCGTCGTGCACAC
GATGGCGTCGGCCGACAAGCCGCCCGCCGTGCTCGGTGAAATGATCGCGCAGGCGCTGGTCGGCACCTTCCTCGGCATTC
TGCTTTCCTACGGTCTGATCGGACCACTCGCGAGCGTCGCTGAACAGCGCGTCACGGAATCGACCAAGATGTTCCAGTGC
ATCAAGGTGACGATTCTCGCAAGCCTGAACGGCTACGCGCCCGCCATCGCCGTCGAATTCGGCCGCAAGGTGCTGTTCTC
GACCGAACGTCCGTCGTTCGCAGAGCTGGAAGAGCACGTGCGCCGCGTGAAGGCCAAATAA

Upstream 100 bases:

>100_bases
CACCGCCCTCATCGGGCTCTCATTCCGCCAAAGTTTTCCGACTGCTTGCCGTAAACCTGAATAACGACGGTCTCCCGTCG
CTTTTCGTGAGGGCTCGGCA

Downstream 100 bases:

>100_bases
GGGACGCGGGCGATGAGCAAGGACAAAGACCGCGCAATCGTTGTCAAGCGCGCCGCGCCGAAGAAAGGCGGCCACCACGG
TGGCGCCTGGAAGCTCGCGT

Product: flagellar motor protein MotA

Products: NA

Alternate protein names: Chemotaxis protein MotA [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MLIFVGTLVTLLSVFGGYALEGGHLGALMQPVEVLMIAGAGVGAFILGNGMKTIKATLRVIPTLFKGAKYNKDVYMELMA
LLYVLLAKARKEGTLTLEADIDDPQKSPIFTQYPKILADHHIVEFLTDYLRLMVGGNMNAFEIESLMDEEIETHHAEGEA
PAHALMKVGDAMPAFGIVAAVMGVVHTMASADKPPAVLGEMIAQALVGTFLGILLSYGLIGPLASVAEQRVTESTKMFQC
IKVTILASLNGYAPAIAVEFGRKVLFSTERPSFAELEEHVRRVKAK

Sequences:

>Translated_286_residues
MLIFVGTLVTLLSVFGGYALEGGHLGALMQPVEVLMIAGAGVGAFILGNGMKTIKATLRVIPTLFKGAKYNKDVYMELMA
LLYVLLAKARKEGTLTLEADIDDPQKSPIFTQYPKILADHHIVEFLTDYLRLMVGGNMNAFEIESLMDEEIETHHAEGEA
PAHALMKVGDAMPAFGIVAAVMGVVHTMASADKPPAVLGEMIAQALVGTFLGILLSYGLIGPLASVAEQRVTESTKMFQC
IKVTILASLNGYAPAIAVEFGRKVLFSTERPSFAELEEHVRRVKAK
>Mature_286_residues
MLIFVGTLVTLLSVFGGYALEGGHLGALMQPVEVLMIAGAGVGAFILGNGMKTIKATLRVIPTLFKGAKYNKDVYMELMA
LLYVLLAKARKEGTLTLEADIDDPQKSPIFTQYPKILADHHIVEFLTDYLRLMVGGNMNAFEIESLMDEEIETHHAEGEA
PAHALMKVGDAMPAFGIVAAVMGVVHTMASADKPPAVLGEMIAQALVGTFLGILLSYGLIGPLASVAEQRVTESTKMFQC
IKVTILASLNGYAPAIAVEFGRKVLFSTERPSFAELEEHVRRVKAK

Specific function: MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel. Overexpression of MotA, with or without MotB, restores motility in a yhjH disruption, (a c-di-GM

COG id: COG1291

COG function: function code N; Flagellar motor component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MotA family [H]

Homologues:

Organism=Escherichia coli, GI1788199, Length=284, Percent_Identity=62.6760563380282, Blast_Score=379, Evalue=1e-106,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000540
- InterPro:   IPR022522
- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 30822; Mature: 30822

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS01307 MOTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIFVGTLVTLLSVFGGYALEGGHLGALMQPVEVLMIAGAGVGAFILGNGMKTIKATLRV
CEEEHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHH
IPTLFKGAKYNKDVYMELMALLYVLLAKARKEGTLTLEADIDDPQKSPIFTQYPKILADH
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
HIVEFLTDYLRLMVGGNMNAFEIESLMDEEIETHHAEGEAPAHALMKVGDAMPAFGIVAA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHH
VMGVVHTMASADKPPAVLGEMIAQALVGTFLGILLSYGLIGPLASVAEQRVTESTKMFQC
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKVTILASLNGYAPAIAVEFGRKVLFSTERPSFAELEEHVRRVKAK
HHHHHHHHCCCCCHHHHHHHCCHHEECCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MLIFVGTLVTLLSVFGGYALEGGHLGALMQPVEVLMIAGAGVGAFILGNGMKTIKATLRV
CEEEHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHH
IPTLFKGAKYNKDVYMELMALLYVLLAKARKEGTLTLEADIDDPQKSPIFTQYPKILADH
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
HIVEFLTDYLRLMVGGNMNAFEIESLMDEEIETHHAEGEAPAHALMKVGDAMPAFGIVAA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHH
VMGVVHTMASADKPPAVLGEMIAQALVGTFLGILLSYGLIGPLASVAEQRVTESTKMFQC
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKVTILASLNGYAPAIAVEFGRKVLFSTERPSFAELEEHVRRVKAK
HHHHHHHHCCCCCHHHHHHHCCHHEECCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6090403; 9097040; 9278503; 3007435; 1719217; 7643400 [H]