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The map label for this gene is cheA [H]

Identifier: 186477720

GI number: 186477720

Start: 3331639

End: 3333957

Strand: Reverse

Name: cheA [H]

Synonym: Bphy_2974

Alternate gene names: 186477720

Gene position: 3333957-3331639 (Counterclockwise)

Preceding gene: 186477721

Following gene: 186477719

Centisome position: 95.83

GC content: 66.41

Gene sequence:

>2319_bases
ATGACACTCGACATCACTCAGTTCTACCAGACGTTCTTCGACGAAGCGGACGAGCTGCTCGCACAGATGGAGCAACTGCT
CCTGAACCTGGACGTCGGCCACCCGGATCCCGAGGATCTCGCGGCCATCTTTCGCGCGGCCCACTCGATCAAGGGCGGCG
CGGCGACGTTCGGCTTCACCGCGCTGACGGAAACGACGCACATTCTCGAGTCGCTGCTCGACCGCGCGCGCAACAACGAA
ATCGTGCTGCGCAAGGACATGATCGACACGTTCCTCGAAACGAAGGACGTGCTGTCCGGCCAGCTGGCCGACTATCGCGC
GAGCGCCGAGCCGGACGCCGCTGTCGCGGCCGCGATCTGCGCGAAGCTCGAACGCCTGCACGCCGAAAGCCGCGGCGAAG
TGCCTGCCGCCGCCGCACCCGCTGCAGCGCCGGCACCCGTGGCAGCGCCCGCTGTGGCAGTGGCCGTGGCGGAAGGCCAT
GCGCCGGAGCATGTCGTCGAACAGGCAGTAGAAGCCGCAGGCGAATGGGCAGAGAACGAACCGGCCCAGACCGGCGCTGC
TTCGTCCGATGCGGCTGCAGGACCCCATCTGAAAATTACGCTACGGGGCGTGGGGGAAAAGGACCAGGAACTGCTCACGG
AAGAACTGGGCAATCTGGGCCGAATCGTCGGACAGGTGAAGGCGGGCGGCGACATCACGCTGTGGCTGGAATCCGATGTG
TCGTCCGACGACATCACGGCCGTGTGCTGTTTCGTGATCGACGAAAGTCAGATCGTGATCGGCCGCGGCGCAGCGCCGGC
AAGCGGCGCGGAGCAGGGTGCGCCTGGAGCATCCGCATCCGCCCAGTCCGAGCCGGCGCCGGCAGCACAGGCAGTAGAGG
GCATGGCGAGCGGCGGCGCGGGGGCGCCAGCCGCCGTCGTGCAGGCTGCCGCCGTTGCACAGCCTGCGGCTCAGCCCGCA
GCACCAGAGGCGCCTGCTCCTGCCGACCCCGCAATCGTTGCACCGGCGGCGGCAGCGGAACCGGCGACGGGCGCGCCGGC
ACCGGCAGCAGCGGCGTCCGCACCGAAAGCAGCGCCTGCATCCGCCGAAGGCGATCGCAAGGCGCGTCCGGCAGCGGCCG
CCAATGCAGAAGGCAGCTCGATCCGCGTGGGCGTCGAAAAGGTCGACCAGCTGATCAACCTGGTCGGCGAACTTGTGATC
ACTCAGGCGATGCTGGCCGAGACCACCAGCACTTTCGATCCGGCGCTGCACGACCGCCTGTTCAATGGCATGGCGCAACT
GGAGCGCAACGCGCGCGATCTCCAGGAAGCCGTCATGTCGATCCGCATGATGCCGATGGATTACGTCTTCAGCCGATTCC
CGCGTCTCGTGCGCGATCTGGCGGCGAAGCTCGGCAAGCAGGTTGAACTCGTCACCTTCGGTCAGGCGACCGAACTCGAC
AAGAGCCTGATCGAACGCATCATCGATCCGCTGACTCACCTCGTGCGCAACAGCCTCGACCACGGCATCGAAACGGTCGA
AGCGCGCAAGGCGGCGGGCAAGGATTCGACGGGCCAGCTGGTGCTGTCGGCGGCCCATCACGGCGGCAACATCGTGATCG
AAGTCAGCGACGACGGCGCCGGTCTGCGTCGCGACAAGATTCTCGCGAAGGCCGCGAAGCAGGGCATGACTGTCAGCGAC
ACGATGACGGACGACGAAGTCTGGAACCTGATCTTCCTGCCGGGCTTCTCGACGGCCGAGCAGGTGACGGACGTCTCGGG
CCGCGGCGTCGGCATGGACGTGGTGAAGCGGAACATCCAGTCGATGGGCGGTCACGTCGAAATCACGTCGCAGGCGGGCA
AGGGCAGCACGACGCGCATCATTCTCCCGCTCACGCTGGCGATTCTCGACGGCATGTCGGTGAAGGTGGGCAGCGAGATT
TTCATCCTGCCGCTGAACTTCGTGATGGAGTCGCTGCAGCCGCAGGCCGACGACATCTACACCGTGGCGAACGGCGAACG
CGTCGTGCGCGTGCGCGGCGAATATCTGCCGCTGGTTGCGCTGCACGAAGTGTTCTCGGTCGACGGTGCGCGCACCGATC
CGACGCAGGGCATCGTCACCATCATGCAGACGGAAGGTCGGCGCTTCGCGATGCTGATCGACGAGCTCGTCGGCCAGCAG
CAGGTGGTGGTGAAGAACCTCGAAACGAACTACCGCAAGGTACACGGCATTTCCGCCGCGACCATTCTCGGCGACGGCAG
CGTCGCGCTGATCGTGGACGTGGCGGCGCTGAACCGCGAAACGCGGGCGTCGCACGGTGCGGCGCTCTCGCTCGCGTGA

Upstream 100 bases:

>100_bases
ACCGAACTGGTCGCGGCGCTCGGCTGAGCGCACCGGACAGGCAACAGCAACCGATATATGGAAGTGGCATAGCAGCCAGG
ACTCTCGCGGTGACACACGC

Downstream 100 bases:

>100_bases
AACCGAAATTCAACTCATCCCAACCGTTTTGGGGGCAAACGTGGCAGAAGTCCAATCCATCAATTCGAACGGCGTAGCCG
GTTCGATCGGCCGCCGCGAC

Product: CheA signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 772; Mature: 771

Protein sequence:

>772_residues
MTLDITQFYQTFFDEADELLAQMEQLLLNLDVGHPDPEDLAAIFRAAHSIKGGAATFGFTALTETTHILESLLDRARNNE
IVLRKDMIDTFLETKDVLSGQLADYRASAEPDAAVAAAICAKLERLHAESRGEVPAAAAPAAAPAPVAAPAVAVAVAEGH
APEHVVEQAVEAAGEWAENEPAQTGAASSDAAAGPHLKITLRGVGEKDQELLTEELGNLGRIVGQVKAGGDITLWLESDV
SSDDITAVCCFVIDESQIVIGRGAAPASGAEQGAPGASASAQSEPAPAAQAVEGMASGGAGAPAAVVQAAAVAQPAAQPA
APEAPAPADPAIVAPAAAAEPATGAPAPAAAASAPKAAPASAEGDRKARPAAAANAEGSSIRVGVEKVDQLINLVGELVI
TQAMLAETTSTFDPALHDRLFNGMAQLERNARDLQEAVMSIRMMPMDYVFSRFPRLVRDLAAKLGKQVELVTFGQATELD
KSLIERIIDPLTHLVRNSLDHGIETVEARKAAGKDSTGQLVLSAAHHGGNIVIEVSDDGAGLRRDKILAKAAKQGMTVSD
TMTDDEVWNLIFLPGFSTAEQVTDVSGRGVGMDVVKRNIQSMGGHVEITSQAGKGSTTRIILPLTLAILDGMSVKVGSEI
FILPLNFVMESLQPQADDIYTVANGERVVRVRGEYLPLVALHEVFSVDGARTDPTQGIVTIMQTEGRRFAMLIDELVGQQ
QVVVKNLETNYRKVHGISAATILGDGSVALIVDVAALNRETRASHGAALSLA

Sequences:

>Translated_772_residues
MTLDITQFYQTFFDEADELLAQMEQLLLNLDVGHPDPEDLAAIFRAAHSIKGGAATFGFTALTETTHILESLLDRARNNE
IVLRKDMIDTFLETKDVLSGQLADYRASAEPDAAVAAAICAKLERLHAESRGEVPAAAAPAAAPAPVAAPAVAVAVAEGH
APEHVVEQAVEAAGEWAENEPAQTGAASSDAAAGPHLKITLRGVGEKDQELLTEELGNLGRIVGQVKAGGDITLWLESDV
SSDDITAVCCFVIDESQIVIGRGAAPASGAEQGAPGASASAQSEPAPAAQAVEGMASGGAGAPAAVVQAAAVAQPAAQPA
APEAPAPADPAIVAPAAAAEPATGAPAPAAAASAPKAAPASAEGDRKARPAAAANAEGSSIRVGVEKVDQLINLVGELVI
TQAMLAETTSTFDPALHDRLFNGMAQLERNARDLQEAVMSIRMMPMDYVFSRFPRLVRDLAAKLGKQVELVTFGQATELD
KSLIERIIDPLTHLVRNSLDHGIETVEARKAAGKDSTGQLVLSAAHHGGNIVIEVSDDGAGLRRDKILAKAAKQGMTVSD
TMTDDEVWNLIFLPGFSTAEQVTDVSGRGVGMDVVKRNIQSMGGHVEITSQAGKGSTTRIILPLTLAILDGMSVKVGSEI
FILPLNFVMESLQPQADDIYTVANGERVVRVRGEYLPLVALHEVFSVDGARTDPTQGIVTIMQTEGRRFAMLIDELVGQQ
QVVVKNLETNYRKVHGISAATILGDGSVALIVDVAALNRETRASHGAALSLA
>Mature_771_residues
TLDITQFYQTFFDEADELLAQMEQLLLNLDVGHPDPEDLAAIFRAAHSIKGGAATFGFTALTETTHILESLLDRARNNEI
VLRKDMIDTFLETKDVLSGQLADYRASAEPDAAVAAAICAKLERLHAESRGEVPAAAAPAAAPAPVAAPAVAVAVAEGHA
PEHVVEQAVEAAGEWAENEPAQTGAASSDAAAGPHLKITLRGVGEKDQELLTEELGNLGRIVGQVKAGGDITLWLESDVS
SDDITAVCCFVIDESQIVIGRGAAPASGAEQGAPGASASAQSEPAPAAQAVEGMASGGAGAPAAVVQAAAVAQPAAQPAA
PEAPAPADPAIVAPAAAAEPATGAPAPAAAASAPKAAPASAEGDRKARPAAAANAEGSSIRVGVEKVDQLINLVGELVIT
QAMLAETTSTFDPALHDRLFNGMAQLERNARDLQEAVMSIRMMPMDYVFSRFPRLVRDLAAKLGKQVELVTFGQATELDK
SLIERIIDPLTHLVRNSLDHGIETVEARKAAGKDSTGQLVLSAAHHGGNIVIEVSDDGAGLRRDKILAKAAKQGMTVSDT
MTDDEVWNLIFLPGFSTAEQVTDVSGRGVGMDVVKRNIQSMGGHVEITSQAGKGSTTRIILPLTLAILDGMSVKVGSEIF
ILPLNFVMESLQPQADDIYTVANGERVVRVRGEYLPLVALHEVFSVDGARTDPTQGIVTIMQTEGRRFAMLIDELVGQQQ
VVVKNLETNYRKVHGISAATILGDGSVALIVDVAALNRETRASHGAALSLA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=416, Percent_Identity=71.3942307692308, Blast_Score=595, Evalue=1e-171,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR015162
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF09078 CheY-binding; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 80383; Mature: 80251

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS00039 DEAD_ATP_HELICASE ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLDITQFYQTFFDEADELLAQMEQLLLNLDVGHPDPEDLAAIFRAAHSIKGGAATFGFT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHH
ALTETTHILESLLDRARNNEIVLRKDMIDTFLETKDVLSGQLADYRASAEPDAAVAAAIC
HHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCHHHHCCCCCCCHHHHHHHHH
AKLERLHAESRGEVPAAAAPAAAPAPVAAPAVAVAVAEGHAPEHVVEQAVEAAGEWAENE
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHEEEECCCCCHHHHHHHHHHHHHCCCCCC
PAQTGAASSDAAAGPHLKITLRGVGEKDQELLTEELGNLGRIVGQVKAGGDITLWLESDV
CCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
SSDDITAVCCFVIDESQIVIGRGAAPASGAEQGAPGASASAQSEPAPAAQAVEGMASGGA
CCCCCEEEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCC
GAPAAVVQAAAVAQPAAQPAAPEAPAPADPAIVAPAAAAEPATGAPAPAAAASAPKAAPA
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCHHCCCCCCCCC
SAEGDRKARPAAAANAEGSSIRVGVEKVDQLINLVGELVITQAMLAETTSTFDPALHDRL
CCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
FNGMAQLERNARDLQEAVMSIRMMPMDYVFSRFPRLVRDLAAKLGKQVELVTFGQATELD
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHH
KSLIERIIDPLTHLVRNSLDHGIETVEARKAAGKDSTGQLVLSAAHHGGNIVIEVSDDGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEECCCCC
GLRRDKILAKAAKQGMTVSDTMTDDEVWNLIFLPGFSTAEQVTDVSGRGVGMDVVKRNIQ
CCHHHHHHHHHHHCCCEEECCCCCHHHEEEEEECCCCCHHHHHCCCCCCCCHHHHHHHHH
SMGGHVEITSQAGKGSTTRIILPLTLAILDGMSVKVGSEIFILPLNFVMESLQPQADDIY
HCCCEEEEECCCCCCCCCEEHHHHHHHHHCCCCEEECCEEEEEEHHHHHHHCCCCCCCEE
TVANGERVVRVRGEYLPLVALHEVFSVDGARTDPTQGIVTIMQTEGRRFAMLIDELVGQQ
EEECCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCH
QVVVKNLETNYRKVHGISAATILGDGSVALIVDVAALNRETRASHGAALSLA
HHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEEHHHHCCHHHHCCCCEEECC
>Mature Secondary Structure 
TLDITQFYQTFFDEADELLAQMEQLLLNLDVGHPDPEDLAAIFRAAHSIKGGAATFGFT
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHH
ALTETTHILESLLDRARNNEIVLRKDMIDTFLETKDVLSGQLADYRASAEPDAAVAAAIC
HHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCHHHHCCCCCCCHHHHHHHHH
AKLERLHAESRGEVPAAAAPAAAPAPVAAPAVAVAVAEGHAPEHVVEQAVEAAGEWAENE
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHEEEECCCCCHHHHHHHHHHHHHCCCCCC
PAQTGAASSDAAAGPHLKITLRGVGEKDQELLTEELGNLGRIVGQVKAGGDITLWLESDV
CCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
SSDDITAVCCFVIDESQIVIGRGAAPASGAEQGAPGASASAQSEPAPAAQAVEGMASGGA
CCCCCEEEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCC
GAPAAVVQAAAVAQPAAQPAAPEAPAPADPAIVAPAAAAEPATGAPAPAAAASAPKAAPA
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCHHCCCCCCCCC
SAEGDRKARPAAAANAEGSSIRVGVEKVDQLINLVGELVITQAMLAETTSTFDPALHDRL
CCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
FNGMAQLERNARDLQEAVMSIRMMPMDYVFSRFPRLVRDLAAKLGKQVELVTFGQATELD
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHH
KSLIERIIDPLTHLVRNSLDHGIETVEARKAAGKDSTGQLVLSAAHHGGNIVIEVSDDGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEECCCCC
GLRRDKILAKAAKQGMTVSDTMTDDEVWNLIFLPGFSTAEQVTDVSGRGVGMDVVKRNIQ
CCHHHHHHHHHHHCCCEEECCCCCHHHEEEEEECCCCCHHHHHCCCCCCCCHHHHHHHHH
SMGGHVEITSQAGKGSTTRIILPLTLAILDGMSVKVGSEIFILPLNFVMESLQPQADDIY
HCCCEEEEECCCCCCCCCEEHHHHHHHHHCCCCEEECCEEEEEEHHHHHHHCCCCCCCEE
TVANGERVVRVRGEYLPLVALHEVFSVDGARTDPTQGIVTIMQTEGRRFAMLIDELVGQQ
EEECCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCH
QVVVKNLETNYRKVHGISAATILGDGSVALIVDVAALNRETRASHGAALSLA
HHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEEHHHHCCHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3278311; 11677609 [H]