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The map label for this gene is cheW [H]

Identifier: 186477719

GI number: 186477719

Start: 3331071

End: 3331598

Strand: Reverse

Name: cheW [H]

Synonym: Bphy_2973

Alternate gene names: 186477719

Gene position: 3331598-3331071 (Counterclockwise)

Preceding gene: 186477720

Following gene: 186477718

Centisome position: 95.76

GC content: 61.93

Gene sequence:

>528_bases
GTGGCAGAAGTCCAATCCATCAATTCGAACGGCGTAGCCGGTTCGATCGGCCGCCGCGACGCGCAAGCCGACGCGAGCGG
TCAGGAATTCCTGATCTTCACGCTCGGCGCAGAAGAGTACGGCATCGACATCCTGAAGGTGCAGGAAATCCGCGGCTACG
ACAGCGTGACGCGCATCGCAAACGCGCCGGAGTTCATCAAGGGCGTGATCAATCTGCGCGGCATCATCGTGCCGATCGTC
GACATGCGCATCAAGTTTCACCTCGGCCGGGTCGAATACGACCATCAGACGGTGGTGATCATTCTGAACGTGGCGGGCCG
CGTGGTCGGGATGGTCGTGGACGGCGTGTCGGACGTGCTGACGCTCGCGGTCGACCAGATCATGCCCGCGCCGGAATTCG
GCGCGACGCTGACGGCGGAATATCTGACGGGCCTCGGCACCGTCGATGGCCGCATGCTGATCCTGATGGACATCGAAAAG
CTGATGACCAGCCGGGAAATGGCATTGACGGAAGCGCTCGGCAGGTAA

Upstream 100 bases:

>100_bases
GTGGCGGCGCTGAACCGCGAAACGCGGGCGTCGCACGGTGCGGCGCTCTCGCTCGCGTGAAACCGAAATTCAACTCATCC
CAACCGTTTTGGGGGCAAAC

Downstream 100 bases:

>100_bases
AGCGGGACGCGGGAACGCCGCAGGGTCCAGACAGGTAATCAGGGAGTACAACAATGCTGAGCAGATGGTCGATCCGGACG
ACGTTGACGGTCGTGGGGAT

Product: CheW protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MAEVQSINSNGVAGSIGRRDAQADASGQEFLIFTLGAEEYGIDILKVQEIRGYDSVTRIANAPEFIKGVINLRGIIVPIV
DMRIKFHLGRVEYDHQTVVIILNVAGRVVGMVVDGVSDVLTLAVDQIMPAPEFGATLTAEYLTGLGTVDGRMLILMDIEK
LMTSREMALTEALGR

Sequences:

>Translated_175_residues
MAEVQSINSNGVAGSIGRRDAQADASGQEFLIFTLGAEEYGIDILKVQEIRGYDSVTRIANAPEFIKGVINLRGIIVPIV
DMRIKFHLGRVEYDHQTVVIILNVAGRVVGMVVDGVSDVLTLAVDQIMPAPEFGATLTAEYLTGLGTVDGRMLILMDIEK
LMTSREMALTEALGR
>Mature_174_residues
AEVQSINSNGVAGSIGRRDAQADASGQEFLIFTLGAEEYGIDILKVQEIRGYDSVTRIANAPEFIKGVINLRGIIVPIVD
MRIKFHLGRVEYDHQTVVIILNVAGRVVGMVVDGVSDVLTLAVDQIMPAPEFGATLTAEYLTGLGTVDGRMLILMDIEKL
MTSREMALTEALGR

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. It physically bridges CheA to the MCPs (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to CheY and CheB [H]

COG id: COG0835

COG function: function code NT; Chemotaxis signal transduction protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheW-like domain [H]

Homologues:

Organism=Escherichia coli, GI1788196, Length=150, Percent_Identity=70, Blast_Score=215, Evalue=1e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002545 [H]

Pfam domain/function: PF01584 CheW [H]

EC number: NA

Molecular weight: Translated: 18949; Mature: 18818

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS50851 CHEW

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEVQSINSNGVAGSIGRRDAQADASGQEFLIFTLGAEEYGIDILKVQEIRGYDSVTRIA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCHHHCEEEEEEEECCCCHHHHHHC
NAPEFIKGVINLRGIIVPIVDMRIKFHLGRVEYDHQTVVIILNVAGRVVGMVVDGVSDVL
CCHHHHHHHHHHHHHEEEEEEEEEEEEECEEEECCCEEEEEEECHHHHHHHHHHHHHHHH
TLAVDQIMPAPEFGATLTAEYLTGLGTVDGRMLILMDIEKLMTSREMALTEALGR
HHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AEVQSINSNGVAGSIGRRDAQADASGQEFLIFTLGAEEYGIDILKVQEIRGYDSVTRIA
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCHHHCEEEEEEEECCCCHHHHHHC
NAPEFIKGVINLRGIIVPIVDMRIKFHLGRVEYDHQTVVIILNVAGRVVGMVVDGVSDVL
CCHHHHHHHHHHHHHEEEEEEEEEEEEECEEEECCCEEEEEEECHHHHHHHHHHHHHHHH
TLAVDQIMPAPEFGATLTAEYLTGLGTVDGRMLILMDIEKLMTSREMALTEALGR
HHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]