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The map label for this gene is tsr [H]

Identifier: 186477718

GI number: 186477718

Start: 3329224

End: 3331017

Strand: Reverse

Name: tsr [H]

Synonym: Bphy_2972

Alternate gene names: 186477718

Gene position: 3331017-3329224 (Counterclockwise)

Preceding gene: 186477719

Following gene: 186477717

Centisome position: 95.74

GC content: 66.89

Gene sequence:

>1794_bases
ATGCTGAGCAGATGGTCGATCCGGACGACGTTGACGGTCGTGGGGATCATTCTGGTTGCACTGACGGTGATCGTCGGGGC
GCTCGGGCTCACCGCGCTGAGCCGCTCGGCCGACGCGCTGGACAGCATGGCGCACGGCGACATGGTCGCGATCCGCACGC
TGAACGACTCGGCGTCGTACTTGCTGCGCTCGCGCGTCTCGCTCGACCGCGTCAACGCACTGACGGCGGCGGGCGAGATC
GAGCAATCGAAGCAGGTGCTCGAGCGCGCGGCGGAACTGCTCGGTAAATCGAACGAAAACTGGCAGGCGTTCCTGAACAC
CCCGAAGAACGGCATCGATCAGTCGCTGATCGACGCCGTGGTCGCGAAGCGCGCGACGGTGATCAGCGACGGTGTGAACC
CCGAGTTCACGGCGCTGCGCGCGAGCGACCTGTCCGGCTATCACGCGATCGCCGACACTAAGATCAGCCCGATGTTCGTC
AACTACGACAACGCGGCGTCGCCCGTCGTCAAGGCGTTGCAGGCGCACGCGGACCAGCAGCAGGAGAACATGGCCGCGCA
GATGGCGGTGCTGCGTGCAGCAATCGTCGCCGTGATCGCGGTCGCGCTGGTGCTCGTGGTGGCAATCCGCTTCGCTCTGC
GCGGCATGATCGTGCAGCCGCTGAACGACGCGGTGGCGTGCTTCGAGCAGATCGCAAGGGGCGACCTGACGCAGCAGGTG
GATGCGACGGGCAGCAATGAAATCGGCCGCCTGTTCAGGGCCGTCAAGGCGATGCAGGACAGCCTGCAGACGATGATCAA
GGCCGTGCACACGAGCGTCGAGTCGATCGACACAGGTGCGCGCGAAATTGCGATGGGCAACACGGACCTGTCGCAGCGCA
CGGAACAGCAGGCTGCGTCGCTGCAGGAAACGGCATCGAGCATGGAGCAGCTGACGGGCACCGTGAAGCAGAACGCCGAC
AACGCGCGCCAGGCGAGCCAGCTTGCCGTGAACGCGTCCGATATCGCGACGCGCGGCGGCGAAGTGGTCAGCCAGGTGGT
GAGCACGATGCAGGACATCGCGACCAGCTCGAACAAGGTCGTCGACATCATCAGCGTGATCGAGGGCATCGCGTTCCAGA
CCAACATTCTCGCGCTGAACGCAGCCGTCGAAGCGGCGCGTGCAGGCGAGCAGGGCCGCGGCTTCGCGGTCGTCGCAGGC
GAAGTGCGCAGCCTCGCGCAGCGCAGCGCGAGCGCGGCGAAGGAAATCAAGGAACTGATCGGCGACTCCGCCGACAAGGT
AGAGAGCGGCTCGGCGCTCGTCGGCCGTGCAGGCACGACGATGGACGAGATCGTGCAGGCCGTGCGCCGCGTGACGGACA
TCATGGGCGAGATCAGCGCGGCCTCGGAAGAACAGTCGGGCGGCATCGAGCAGGTCAACCGCGCTGTCGTGCAGATGGAC
GAAGTTACGCAGCAGAATGCCGCACTCGTCGAACAGGCTGCGGCGGCTGCCGCGTCGCTCGAAGAGCAGACCCGCTCGCT
GCAGACGGTGATCGGGAAATGGCGGGTAGCCGGTGCGCAAGGCGGCGCGAAGGCGATGCCGTCGGCGAACACGGCGAAGA
GCCGCGTGAAAGCCGCCGTCGCGCATGCCGCGAAGGCGCCGGCTCCTGCGCAACCTGTCGTCGCGAAGACGGAAGCGGCA
GCGTCCGCACGCGTCGAACCCGTGGTGAAGAAGGCGCCCGCGGCGGCCGCCGAACCGGCGCCGCGAAAGACAGCGGCGGC
TGCGACCTCGGACGCCGACTGGGAAACGTTCTGA

Upstream 100 bases:

>100_bases
TGATGACCAGCCGGGAAATGGCATTGACGGAAGCGCTCGGCAGGTAAAGCGGGACGCGGGAACGCCGCAGGGTCCAGACA
GGTAATCAGGGAGTACAACA

Downstream 100 bases:

>100_bases
CGCGCGGTGGATGGATATGCGAGTTCCCGGCACCTCGTTTCGAGACGGACGTTTTCGCGCGATGCGTCGTGAACGCGCAG
GCGCAGCGGGCGTTGGGTTC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: MCP-I; Serine chemoreceptor protein [H]

Number of amino acids: Translated: 597; Mature: 597

Protein sequence:

>597_residues
MLSRWSIRTTLTVVGIILVALTVIVGALGLTALSRSADALDSMAHGDMVAIRTLNDSASYLLRSRVSLDRVNALTAAGEI
EQSKQVLERAAELLGKSNENWQAFLNTPKNGIDQSLIDAVVAKRATVISDGVNPEFTALRASDLSGYHAIADTKISPMFV
NYDNAASPVVKALQAHADQQQENMAAQMAVLRAAIVAVIAVALVLVVAIRFALRGMIVQPLNDAVACFEQIARGDLTQQV
DATGSNEIGRLFRAVKAMQDSLQTMIKAVHTSVESIDTGAREIAMGNTDLSQRTEQQAASLQETASSMEQLTGTVKQNAD
NARQASQLAVNASDIATRGGEVVSQVVSTMQDIATSSNKVVDIISVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAG
EVRSLAQRSASAAKEIKELIGDSADKVESGSALVGRAGTTMDEIVQAVRRVTDIMGEISAASEEQSGGIEQVNRAVVQMD
EVTQQNAALVEQAAAAAASLEEQTRSLQTVIGKWRVAGAQGGAKAMPSANTAKSRVKAAVAHAAKAPAPAQPVVAKTEAA
ASARVEPVVKKAPAAAAEPAPRKTAAAATSDADWETF

Sequences:

>Translated_597_residues
MLSRWSIRTTLTVVGIILVALTVIVGALGLTALSRSADALDSMAHGDMVAIRTLNDSASYLLRSRVSLDRVNALTAAGEI
EQSKQVLERAAELLGKSNENWQAFLNTPKNGIDQSLIDAVVAKRATVISDGVNPEFTALRASDLSGYHAIADTKISPMFV
NYDNAASPVVKALQAHADQQQENMAAQMAVLRAAIVAVIAVALVLVVAIRFALRGMIVQPLNDAVACFEQIARGDLTQQV
DATGSNEIGRLFRAVKAMQDSLQTMIKAVHTSVESIDTGAREIAMGNTDLSQRTEQQAASLQETASSMEQLTGTVKQNAD
NARQASQLAVNASDIATRGGEVVSQVVSTMQDIATSSNKVVDIISVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAG
EVRSLAQRSASAAKEIKELIGDSADKVESGSALVGRAGTTMDEIVQAVRRVTDIMGEISAASEEQSGGIEQVNRAVVQMD
EVTQQNAALVEQAAAAAASLEEQTRSLQTVIGKWRVAGAQGGAKAMPSANTAKSRVKAAVAHAAKAPAPAQPVVAKTEAA
ASARVEPVVKKAPAAAAEPAPRKTAAAATSDADWETF
>Mature_597_residues
MLSRWSIRTTLTVVGIILVALTVIVGALGLTALSRSADALDSMAHGDMVAIRTLNDSASYLLRSRVSLDRVNALTAAGEI
EQSKQVLERAAELLGKSNENWQAFLNTPKNGIDQSLIDAVVAKRATVISDGVNPEFTALRASDLSGYHAIADTKISPMFV
NYDNAASPVVKALQAHADQQQENMAAQMAVLRAAIVAVIAVALVLVVAIRFALRGMIVQPLNDAVACFEQIARGDLTQQV
DATGSNEIGRLFRAVKAMQDSLQTMIKAVHTSVESIDTGAREIAMGNTDLSQRTEQQAASLQETASSMEQLTGTVKQNAD
NARQASQLAVNASDIATRGGEVVSQVVSTMQDIATSSNKVVDIISVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAG
EVRSLAQRSASAAKEIKELIGDSADKVESGSALVGRAGTTMDEIVQAVRRVTDIMGEISAASEEQSGGIEQVNRAVVQMD
EVTQQNAALVEQAAAAAASLEEQTRSLQTVIGKWRVAGAQGGAKAMPSANTAKSRVKAAVAHAAKAPAPAQPVVAKTEAA
ASARVEPVVKKAPAAAAEPAPRKTAAAATSDADWETF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=503, Percent_Identity=45.3280318091451, Blast_Score=348, Evalue=4e-97,
Organism=Escherichia coli, GI1787690, Length=474, Percent_Identity=45.7805907172996, Blast_Score=337, Evalue=2e-93,
Organism=Escherichia coli, GI1788195, Length=342, Percent_Identity=58.4795321637427, Blast_Score=332, Evalue=6e-92,
Organism=Escherichia coli, GI1788194, Length=348, Percent_Identity=55.4597701149425, Blast_Score=328, Evalue=4e-91,
Organism=Escherichia coli, GI1789453, Length=325, Percent_Identity=41.8461538461538, Blast_Score=234, Evalue=1e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 62304; Mature: 62304

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSRWSIRTTLTVVGIILVALTVIVGALGLTALSRSADALDSMAHGDMVAIRTLNDSASY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHH
LLRSRVSLDRVNALTAAGEIEQSKQVLERAAELLGKSNENWQAFLNTPKNGIDQSLIDAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEECCCCCCCHHHHHHHH
VAKRATVISDGVNPEFTALRASDLSGYHAIADTKISPMFVNYDNAASPVVKALQAHADQQ
HHHHHHHHHCCCCCCHHEEECCCCCCCHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHH
QENMAAQMAVLRAAIVAVIAVALVLVVAIRFALRGMIVQPLNDAVACFEQIARGDLTQQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
DATGSNEIGRLFRAVKAMQDSLQTMIKAVHTSVESIDTGAREIAMGNTDLSQRTEQQAAS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHH
LQETASSMEQLTGTVKQNADNARQASQLAVNASDIATRGGEVVSQVVSTMQDIATSSNKV
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHCHHHHHHHHHHHHHHHHCCCCHH
VDIISVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRSLAQRSASAAKEIKELI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
GDSADKVESGSALVGRAGTTMDEIVQAVRRVTDIMGEISAASEEQSGGIEQVNRAVVQMD
CCCHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHH
EVTQQNAALVEQAAAAAASLEEQTRSLQTVIGKWRVAGAQGGAKAMPSANTAKSRVKAAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
AHAAKAPAPAQPVVAKTEAAASARVEPVVKKAPAAAAEPAPRKTAAAATSDADWETF
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCC
>Mature Secondary Structure
MLSRWSIRTTLTVVGIILVALTVIVGALGLTALSRSADALDSMAHGDMVAIRTLNDSASY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHH
LLRSRVSLDRVNALTAAGEIEQSKQVLERAAELLGKSNENWQAFLNTPKNGIDQSLIDAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEECCCCCCCHHHHHHHH
VAKRATVISDGVNPEFTALRASDLSGYHAIADTKISPMFVNYDNAASPVVKALQAHADQQ
HHHHHHHHHCCCCCCHHEEECCCCCCCHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHH
QENMAAQMAVLRAAIVAVIAVALVLVVAIRFALRGMIVQPLNDAVACFEQIARGDLTQQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
DATGSNEIGRLFRAVKAMQDSLQTMIKAVHTSVESIDTGAREIAMGNTDLSQRTEQQAAS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHH
LQETASSMEQLTGTVKQNADNARQASQLAVNASDIATRGGEVVSQVVSTMQDIATSSNKV
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHCHHHHHHHHHHHHHHHHCCCCHH
VDIISVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRSLAQRSASAAKEIKELI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
GDSADKVESGSALVGRAGTTMDEIVQAVRRVTDIMGEISAASEEQSGGIEQVNRAVVQMD
CCCHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHH
EVTQQNAALVEQAAAAAASLEEQTRSLQTVIGKWRVAGAQGGAKAMPSANTAKSRVKAAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
AHAAKAPAPAQPVVAKTEAAASARVEPVVKKAPAAAAEPAPRKTAAAATSDADWETF
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6402709; 7610040; 9278503; 8384293; 6213619; 2033064; 10466731 [H]