| Definition | Burkholderia phymatum STM815 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010622 |
| Length | 3,479,187 |
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The map label for this gene is mrcA [H]
Identifier: 186477547
GI number: 186477547
Start: 3151478
End: 3153868
Strand: Direct
Name: mrcA [H]
Synonym: Bphy_2799
Alternate gene names: 186477547
Gene position: 3151478-3153868 (Clockwise)
Preceding gene: 186477539
Following gene: 186477549
Centisome position: 90.58
GC content: 62.82
Gene sequence:
>2391_bases ATGCAATCCACGACTCCTACGTCTCCGCCGCCGGCGCCGCAGAAGCGCAAGCGCCCTCTCTGGCTGAAGATCGTCCTCGG CTTCGTCGGCCTGATCTTTGCCGGGATCATCAGCGCGGTGCTCGTGCTGGGTTACGCGCTGGTCGTCGCCACGCCGAACC TGCCGTCGCTCGACGCGCTCACCGACTATCGTCCGAAGGTACCGTTGCGCATCTACACCGCCGACCACGTTCTGATCGGC GAATTCGGCGAGGAGCGGCGCGACATCGTTCACATGCGTGAGGTGCCGGACAACCTCAAGAAAGCCGTGCTCGCGATCGA AGACGCGCGCTTCTACGATCATGGCGGCGTCGACCTGACGGGTATCGTGCGCGCCGGCGTGGTCGCGCTCACGAACGGCC ACGCAACGCAAGGCGCGAGCACGATCACGATGCAGGTCGCGCGCAACTTCTTTCTCTCCAGCGAAAAGACGTACACGCGC AAGATCTACGAGATGCTGCTCGCGTACAAGATCGAATCGAAGTTGAGCAAGGATCAGATTCTCGAGGTGTACATGAATCA GATCTATCTGGGCCAGCGCGCGTATGGTTTTGCCAGCGCCGCGCGCGTGTACTTCGGCAAAGACCTGAAAGACCTGTCGC TCGCCGAGTGCGCGATGCTCGCAGGTCTGCCGAAAGCGCCGTCGGCATACAACCCCGTGGTGAATCCGAAACGCGCGAAG GTGCGTCAGGAATACATCCTCCAGCGCATGCTCGAACTTGGCTACATCACACGGGACCAATACGACACGGCGAGCCGCCA ACCGCTCATCGTGAAGGGCGCGGGCAAGGAATTCAGCGTGCACGCAGAGTACGTCGCGGAAATGGTGCGGCAGATGATGT ACGCGCAATACCGTGAAGAGGCGTACACGCGTGGCCTGAACGTCGTGACGACAATCGACTCCGCCGATCAGGACGCCGCC TATCGCGCGCTGCGCAAGGGCTTGCTGGACTACGAGCGGCGTCACGGCTATCGCGGTCCGGAAGCGTTCATCGACTTGCC GGCCGATGCCGACGAGCGCGAGCAGGCTATCGACGACGCGCTGCTCGAACATCCGGACAATGGCGAGATCATTGCAGCCG TGGTGACGTCGGCGAGTCCAAAGCAGGTGCAAGCGACGCTGATCGACGGCAATGTCGTGACAATCCAGGGCGACGGGCTG CGCTACGCTAACTTCGCGCTGAGCGCGCGCGCGCAGCCGAACCAGCGCGTGCGGCCGGGCGCCGTGATCCGTATCGTGAA GGGTGAGGATGGCAGCTGGTCGATCACGCAGTTGCCGCAGATCGAAGGTGCGTTTGTTTCCGTCGTGCCGCAGGATGGCG CGATCCGCGCACTTGTAGGCGGCTTCGATTTCAACAAGAACAAGTTCAATCATGTGACGCAGGCCTGGCGGCAGCCGGGT TCGAGCTTCAAGCCGTTCATCTACTCGGCTTCGCTCGAAAAAGGCCTCGGCCCCGCAACCGTCATCAACGACGCGCCGCT CTTCTTCAGCGCGGCCGAAACGGGCGGCCAGGCGTGGGAACCGAAGAACTACGGCGGCGGCTTCGACGGCCCAATGTCGA TGCGCACCGCGCTGCAGAAGTCGAAGAACCTCGTGTCGATCCGCATCCTCAATCACATCGGCACGAAGTACGCGCAGCAG TACATCACGCATTTCGGTTTCGATGCGGACCGGCATCCCGCATATCTGCCGATGGCGCTCGGCGCTGGCCTCGTCACGCC GCTGCAGATGGCAGCGGGCTACTCGGTGTTCGCGAACGGCGGCTATCGCGTGAATCCGTATCTGATCGCCGAAGTGACCG ATCAGCGCGGCATGGTGGTCGCGCATGCGGAACCGCTCGTCGCGGCCAGCAACGCGCCGCATGCCATCGAGCCGCGCAAC GCCTACGTGATGAACAGCCTGTTGACAAGTGTCGCGCAGCGCGGCACGGGAGCGAAATCGAACGTGTTGAAGCGCACCGA TCTCGCGGGCAAGACGGGCACCACGAATGATTCGCGCGACGCGTGGTTCGCCGGCTATCAGCACACGCTGTGCGCGATTG CGTGGATAGGCTACGACAATCCGCGCAGTCTCGGCGACAAGGAAACGGGCGGCGGGCTCGCGCTGCCCGTGTGGATCGAG TACATGGGACGCGCGCTCAAGGGTGTGCCCGAGTACAAGATGCCGATGCCCGAAGACGTCGTGACGATAGGCGACGAGTT GTACTTCGACGACTTCACGCCGGGCAACGGTTTCGTGTCGACGGTCGGCGTATCGCAGGCGTCAGCGGAAGCGAGCGGTA CAAGCGGCGCGCCGGCGCAGGTCGATGCGCAAGAAAAAGAAAACATCATGAATCTGTTCAGGGGCCACTAG
Upstream 100 bases:
>100_bases CTAGAGTGTTCTCATCGCCGCGCAATTGCGGCAGCCGTAAGCACGCCGAAAGCTGCCAGATCGGGCGGCTATAATCGCGG GACCGTTTTCTGGTGTTCAT
Downstream 100 bases:
>100_bases GTCTGCCGGCTCCCTGAAAAAAAGCCGCCGCGTATTGTACGCGGCGGCTTTTTACTTTCCGCGAGCGACACCGGCTGCGG GTGCGCCAAAACGCTCTGCT
Product: 1A family penicillin-binding protein
Products: NA
Alternate protein names: PBP-1a; PBP1a; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 796; Mature: 796
Protein sequence:
>796_residues MQSTTPTSPPPAPQKRKRPLWLKIVLGFVGLIFAGIISAVLVLGYALVVATPNLPSLDALTDYRPKVPLRIYTADHVLIG EFGEERRDIVHMREVPDNLKKAVLAIEDARFYDHGGVDLTGIVRAGVVALTNGHATQGASTITMQVARNFFLSSEKTYTR KIYEMLLAYKIESKLSKDQILEVYMNQIYLGQRAYGFASAARVYFGKDLKDLSLAECAMLAGLPKAPSAYNPVVNPKRAK VRQEYILQRMLELGYITRDQYDTASRQPLIVKGAGKEFSVHAEYVAEMVRQMMYAQYREEAYTRGLNVVTTIDSADQDAA YRALRKGLLDYERRHGYRGPEAFIDLPADADEREQAIDDALLEHPDNGEIIAAVVTSASPKQVQATLIDGNVVTIQGDGL RYANFALSARAQPNQRVRPGAVIRIVKGEDGSWSITQLPQIEGAFVSVVPQDGAIRALVGGFDFNKNKFNHVTQAWRQPG SSFKPFIYSASLEKGLGPATVINDAPLFFSAAETGGQAWEPKNYGGGFDGPMSMRTALQKSKNLVSIRILNHIGTKYAQQ YITHFGFDADRHPAYLPMALGAGLVTPLQMAAGYSVFANGGYRVNPYLIAEVTDQRGMVVAHAEPLVAASNAPHAIEPRN AYVMNSLLTSVAQRGTGAKSNVLKRTDLAGKTGTTNDSRDAWFAGYQHTLCAIAWIGYDNPRSLGDKETGGGLALPVWIE YMGRALKGVPEYKMPMPEDVVTIGDELYFDDFTPGNGFVSTVGVSQASAEASGTSGAPAQVDAQEKENIMNLFRGH
Sequences:
>Translated_796_residues MQSTTPTSPPPAPQKRKRPLWLKIVLGFVGLIFAGIISAVLVLGYALVVATPNLPSLDALTDYRPKVPLRIYTADHVLIG EFGEERRDIVHMREVPDNLKKAVLAIEDARFYDHGGVDLTGIVRAGVVALTNGHATQGASTITMQVARNFFLSSEKTYTR KIYEMLLAYKIESKLSKDQILEVYMNQIYLGQRAYGFASAARVYFGKDLKDLSLAECAMLAGLPKAPSAYNPVVNPKRAK VRQEYILQRMLELGYITRDQYDTASRQPLIVKGAGKEFSVHAEYVAEMVRQMMYAQYREEAYTRGLNVVTTIDSADQDAA YRALRKGLLDYERRHGYRGPEAFIDLPADADEREQAIDDALLEHPDNGEIIAAVVTSASPKQVQATLIDGNVVTIQGDGL RYANFALSARAQPNQRVRPGAVIRIVKGEDGSWSITQLPQIEGAFVSVVPQDGAIRALVGGFDFNKNKFNHVTQAWRQPG SSFKPFIYSASLEKGLGPATVINDAPLFFSAAETGGQAWEPKNYGGGFDGPMSMRTALQKSKNLVSIRILNHIGTKYAQQ YITHFGFDADRHPAYLPMALGAGLVTPLQMAAGYSVFANGGYRVNPYLIAEVTDQRGMVVAHAEPLVAASNAPHAIEPRN AYVMNSLLTSVAQRGTGAKSNVLKRTDLAGKTGTTNDSRDAWFAGYQHTLCAIAWIGYDNPRSLGDKETGGGLALPVWIE YMGRALKGVPEYKMPMPEDVVTIGDELYFDDFTPGNGFVSTVGVSQASAEASGTSGAPAQVDAQEKENIMNLFRGH >Mature_796_residues MQSTTPTSPPPAPQKRKRPLWLKIVLGFVGLIFAGIISAVLVLGYALVVATPNLPSLDALTDYRPKVPLRIYTADHVLIG EFGEERRDIVHMREVPDNLKKAVLAIEDARFYDHGGVDLTGIVRAGVVALTNGHATQGASTITMQVARNFFLSSEKTYTR KIYEMLLAYKIESKLSKDQILEVYMNQIYLGQRAYGFASAARVYFGKDLKDLSLAECAMLAGLPKAPSAYNPVVNPKRAK VRQEYILQRMLELGYITRDQYDTASRQPLIVKGAGKEFSVHAEYVAEMVRQMMYAQYREEAYTRGLNVVTTIDSADQDAA YRALRKGLLDYERRHGYRGPEAFIDLPADADEREQAIDDALLEHPDNGEIIAAVVTSASPKQVQATLIDGNVVTIQGDGL RYANFALSARAQPNQRVRPGAVIRIVKGEDGSWSITQLPQIEGAFVSVVPQDGAIRALVGGFDFNKNKFNHVTQAWRQPG SSFKPFIYSASLEKGLGPATVINDAPLFFSAAETGGQAWEPKNYGGGFDGPMSMRTALQKSKNLVSIRILNHIGTKYAQQ YITHFGFDADRHPAYLPMALGAGLVTPLQMAAGYSVFANGGYRVNPYLIAEVTDQRGMVVAHAEPLVAASNAPHAIEPRN AYVMNSLLTSVAQRGTGAKSNVLKRTDLAGKTGTTNDSRDAWFAGYQHTLCAIAWIGYDNPRSLGDKETGGGLALPVWIE YMGRALKGVPEYKMPMPEDVVTIGDELYFDDFTPGNGFVSTVGVSQASAEASGTSGAPAQVDAQEKENIMNLFRGH
Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal
COG id: COG5009
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI87082258, Length=584, Percent_Identity=45.0342465753425, Blast_Score=504, Evalue=1e-143, Organism=Escherichia coli, GI1786343, Length=257, Percent_Identity=38.9105058365759, Blast_Score=160, Evalue=3e-40, Organism=Escherichia coli, GI1788867, Length=228, Percent_Identity=31.5789473684211, Blast_Score=115, Evalue=1e-26, Organism=Escherichia coli, GI1789601, Length=178, Percent_Identity=33.7078651685393, Blast_Score=97, Evalue=4e-21,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-; 3.4.-.- [C]
Molecular weight: Translated: 86979; Mature: 86979
Theoretical pI: Translated: 7.81; Mature: 7.81
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 2.5 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 2.5 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MQSTTPTSPPPAPQKRKRPLWLKIVLGFVGLIFAGIISAVLVLGYALVVATPNLPSLDAL CCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHH TDYRPKVPLRIYTADHVLIGEFGEERRDIVHMREVPDNLKKAVLAIEDARFYDHGGVDLT HCCCCCCCEEEEECCEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCEECCCCCCHH GIVRAGVVALTNGHATQGASTITMQVARNFFLSSEKTYTRKIYEMLLAYKIESKLSKDQI HHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHH LEVYMNQIYLGQRAYGFASAARVYFGKDLKDLSLAECAMLAGLPKAPSAYNPVVNPKRAK HHHHHHHHHHCCHHHCHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHH VRQEYILQRMLELGYITRDQYDTASRQPLIVKGAGKEFSVHAEYVAEMVRQMMYAQYREE HHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHH AYTRGLNVVTTIDSADQDAAYRALRKGLLDYERRHGYRGPEAFIDLPADADEREQAIDDA HHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHEEECCCCCCHHHHHHHHH LLEHPDNGEIIAAVVTSASPKQVQATLIDGNVVTIQGDGLRYANFALSARAQPNQRVRPG HHCCCCCCCEEEEEEECCCCCEEEEEEECCEEEEEECCCEEEEEEEEECCCCCCCCCCCC AVIRIVKGEDGSWSITQLPQIEGAFVSVVPQDGAIRALVGGFDFNKNKFNHVTQAWRQPG EEEEEEECCCCCEEEEECCCCCCCEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHCCC SSFKPFIYSASLEKGLGPATVINDAPLFFSAAETGGQAWEPKNYGGGFDGPMSMRTALQK CCCCCEEEECCHHHCCCCEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHH SKNLVSIRILNHIGTKYAQQYITHFGFDADRHPAYLPMALGAGLVTPLQMAAGYSVFANG CCCEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHCCCHHHHHHHHCCCEEEECC GYRVNPYLIAEVTDQRGMVVAHAEPLVAASNAPHAIEPRNAYVMNSLLTSVAQRGTGAKS CEEECCEEEEEECCCCCEEEEECCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHH NVLKRTDLAGKTGTTNDSRDAWFAGYQHTLCAIAWIGYDNPRSLGDKETGGGLALPVWIE HHHHHHCCCCCCCCCCCCCCHHHHCHHHEEEEEEEECCCCCCCCCCCCCCCCEEHHHHHH YMGRALKGVPEYKMPMPEDVVTIGDELYFDDFTPGNGFVSTVGVSQASAEASGTSGAPAQ HHHHHHCCCCCCCCCCCHHHEECCCEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCC VDAQEKENIMNLFRGH CCHHHHHHHHHHHCCC >Mature Secondary Structure MQSTTPTSPPPAPQKRKRPLWLKIVLGFVGLIFAGIISAVLVLGYALVVATPNLPSLDAL CCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHH TDYRPKVPLRIYTADHVLIGEFGEERRDIVHMREVPDNLKKAVLAIEDARFYDHGGVDLT HCCCCCCCEEEEECCEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCEECCCCCCHH GIVRAGVVALTNGHATQGASTITMQVARNFFLSSEKTYTRKIYEMLLAYKIESKLSKDQI HHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHH LEVYMNQIYLGQRAYGFASAARVYFGKDLKDLSLAECAMLAGLPKAPSAYNPVVNPKRAK HHHHHHHHHHCCHHHCHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHH VRQEYILQRMLELGYITRDQYDTASRQPLIVKGAGKEFSVHAEYVAEMVRQMMYAQYREE HHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHH AYTRGLNVVTTIDSADQDAAYRALRKGLLDYERRHGYRGPEAFIDLPADADEREQAIDDA HHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHEEECCCCCCHHHHHHHHH LLEHPDNGEIIAAVVTSASPKQVQATLIDGNVVTIQGDGLRYANFALSARAQPNQRVRPG HHCCCCCCCEEEEEEECCCCCEEEEEEECCEEEEEECCCEEEEEEEEECCCCCCCCCCCC AVIRIVKGEDGSWSITQLPQIEGAFVSVVPQDGAIRALVGGFDFNKNKFNHVTQAWRQPG EEEEEEECCCCCEEEEECCCCCCCEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHCCC SSFKPFIYSASLEKGLGPATVINDAPLFFSAAETGGQAWEPKNYGGGFDGPMSMRTALQK CCCCCEEEECCHHHCCCCEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHH SKNLVSIRILNHIGTKYAQQYITHFGFDADRHPAYLPMALGAGLVTPLQMAAGYSVFANG CCCEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHCCCHHHHHHHHCCCEEEECC GYRVNPYLIAEVTDQRGMVVAHAEPLVAASNAPHAIEPRNAYVMNSLLTSVAQRGTGAKS CEEECCEEEEEECCCCCEEEEECCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHH NVLKRTDLAGKTGTTNDSRDAWFAGYQHTLCAIAWIGYDNPRSLGDKETGGGLALPVWIE HHHHHHCCCCCCCCCCCCCCHHHHCHHHEEEEEEEECCCCCCCCCCCCCCCCEEHHHHHH YMGRALKGVPEYKMPMPEDVVTIGDELYFDDFTPGNGFVSTVGVSQASAEASGTSGAPAQ HHHHHHCCCCCCCCCCCHHHEECCCEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCC VDAQEKENIMNLFRGH CCHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA