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The map label for this gene is aroB [H]

Identifier: 186477541

GI number: 186477541

Start: 3145370

End: 3146461

Strand: Reverse

Name: aroB [H]

Synonym: Bphy_2793

Alternate gene names: 186477541

Gene position: 3146461-3145370 (Counterclockwise)

Preceding gene: 186477542

Following gene: 186477540

Centisome position: 90.44

GC content: 65.38

Gene sequence:

>1092_bases
ATGACTGCCATGATTACCGTCAACGTCGAACTGGGCGAGCGCGCCTATCCCATCCATATCGGCGCCGATCTGATCGGCAA
GAGCGAGCTGTTCGCGCCGCACATCCGCGGCGCGTCGGTGACGATCGTCACGAATACGACGGTCGACCCGCTGTACGGCG
ACGCCTTGCGCCAGTCCCTCGCGCCGCTCGGCAAGGAAGTGACGACGGTCGTGTTGCCCGATGGCGAGGCGCACAAGAAC
TGGGAAACGCTGAATCTGATTTTCGACGCTCTGCTCGGCGCGCGGGCCGACCGTAAGACCACGCTCATCGCGCTCGGCGG
CGGCGTGATTGGCGACATGACGGGGTTCGCGGCCGCCTGCTACATGCGCGGCGTGCCGTTCATCCAGGTGCCGACCACGC
TGTTGTCGCAGGTCGATTCGTCGGTGGGCGGCAAGACGGGCATCAACCATCCGCTCGGCAAGAACATGATCGGCGCGTTC
TACCAGCCGCAGGCCGTGATCGCCGACATTGGCGCGCTGCGCACGCTGCCGTCGCGCGAACTGGCCGCGGGCATCGCGGA
AGTCATCAAGACGGGCGCGATTGCCGATGCCGGTTTCTTCGAGTGGATCGAAGCGAACATCGAAGCGCTCAACGGCTGTG
ACGCGCAAGCGCTGGCTGAAGCGGTCAAGCGTTCGTGCGAGATCAAGGCGTCCGTGGTCGCCGCGGACGAGCGGGAAGGC
GGCCTGCGCGCTATCCTCAATTTTGGCCACACGTTCGGTCACGCTATCGAAGCGGGACTTGGCTACGGCGAGTGGCTGCA
CGGCGAAGCGGTGGGCTGCGGAATGGTGATGGCAGCCGATCTGTCCGTGCGTCTCGGGCATCTGGACGAAGCCGCGCGCA
AGCGGCTCGTCGCCGTCATCGAGGCGGCACATCTGCCTGTTCGGGCGCCCGCGCTCGGCGCACCACGCTACGTCGATCTG
ATGCGGGTCGACAAGAAGGCAGAAGCGGGCGAAATCAAGTTCATCCTGCTGAAGCGTTTCGGCGACACACTGATCACCCG
TGCGCCCGACGACGCGGTGCTCAAAACCCTCGACGCAAGCGTCGGCGCCTGA

Upstream 100 bases:

>100_bases
ATCGAAACGGGCCGTCCGTCCGTCAACGGGCTCGTCAATATGGTGCTGATGCAGCTCGAGATGGCGGGCGTCGCCAAGCC
TACTGCGTCATAATGACGAG

Downstream 100 bases:

>100_bases
CGCGCAGCGCAGCGGCACCACCTGCGGCCCTCGCGTCTGATTCGGAGATATCGGTGAGCGAAATACGCAGCGACAATCTA
AGCGAATCGACCGACATTCC

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MTAMITVNVELGERAYPIHIGADLIGKSELFAPHIRGASVTIVTNTTVDPLYGDALRQSLAPLGKEVTTVVLPDGEAHKN
WETLNLIFDALLGARADRKTTLIALGGGVIGDMTGFAAACYMRGVPFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAF
YQPQAVIADIGALRTLPSRELAAGIAEVIKTGAIADAGFFEWIEANIEALNGCDAQALAEAVKRSCEIKASVVAADEREG
GLRAILNFGHTFGHAIEAGLGYGEWLHGEAVGCGMVMAADLSVRLGHLDEAARKRLVAVIEAAHLPVRAPALGAPRYVDL
MRVDKKAEAGEIKFILLKRFGDTLITRAPDDAVLKTLDASVGA

Sequences:

>Translated_363_residues
MTAMITVNVELGERAYPIHIGADLIGKSELFAPHIRGASVTIVTNTTVDPLYGDALRQSLAPLGKEVTTVVLPDGEAHKN
WETLNLIFDALLGARADRKTTLIALGGGVIGDMTGFAAACYMRGVPFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAF
YQPQAVIADIGALRTLPSRELAAGIAEVIKTGAIADAGFFEWIEANIEALNGCDAQALAEAVKRSCEIKASVVAADEREG
GLRAILNFGHTFGHAIEAGLGYGEWLHGEAVGCGMVMAADLSVRLGHLDEAARKRLVAVIEAAHLPVRAPALGAPRYVDL
MRVDKKAEAGEIKFILLKRFGDTLITRAPDDAVLKTLDASVGA
>Mature_362_residues
TAMITVNVELGERAYPIHIGADLIGKSELFAPHIRGASVTIVTNTTVDPLYGDALRQSLAPLGKEVTTVVLPDGEAHKNW
ETLNLIFDALLGARADRKTTLIALGGGVIGDMTGFAAACYMRGVPFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFY
QPQAVIADIGALRTLPSRELAAGIAEVIKTGAIADAGFFEWIEANIEALNGCDAQALAEAVKRSCEIKASVVAADEREGG
LRAILNFGHTFGHAIEAGLGYGEWLHGEAVGCGMVMAADLSVRLGHLDEAARKRLVAVIEAAHLPVRAPALGAPRYVDLM
RVDKKAEAGEIKFILLKRFGDTLITRAPDDAVLKTLDASVGA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=334, Percent_Identity=57.4850299401198, Blast_Score=362, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6320332, Length=367, Percent_Identity=38.4196185286104, Blast_Score=214, Evalue=1e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 38222; Mature: 38090

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAMITVNVELGERAYPIHIGADLIGKSELFAPHIRGASVTIVTNTTVDPLYGDALRQSL
CEEEEEEEEEECCEEEEEEECCCCCCCCHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHH
APLGKEVTTVVLPDGEAHKNWETLNLIFDALLGARADRKTTLIALGGGVIGDMTGFAAAC
HHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHH
YMRGVPFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFYQPQAVIADIGALRTLPSRE
HHCCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHCCCCHH
LAAGIAEVIKTGAIADAGFFEWIEANIEALNGCDAQALAEAVKRSCEIKASVVAADEREG
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEEEEECCCCCC
GLRAILNFGHTFGHAIEAGLGYGEWLHGEAVGCGMVMAADLSVRLGHLDEAARKRLVAVI
CHHHHHHHCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCEEEECCHHHHHHHHHHHHH
EAAHLPVRAPALGAPRYVDLMRVDKKAEAGEIKFILLKRFGDTLITRAPDDAVLKTLDAS
HHHCCCCCCCCCCCCCHHHHHHHCCCCCCCCEEEEEEEHHCCHHEECCCCHHHHHHHHHH
VGA
CCC
>Mature Secondary Structure 
TAMITVNVELGERAYPIHIGADLIGKSELFAPHIRGASVTIVTNTTVDPLYGDALRQSL
EEEEEEEEEECCEEEEEEECCCCCCCCHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHH
APLGKEVTTVVLPDGEAHKNWETLNLIFDALLGARADRKTTLIALGGGVIGDMTGFAAAC
HHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHH
YMRGVPFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFYQPQAVIADIGALRTLPSRE
HHCCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHCCCCHH
LAAGIAEVIKTGAIADAGFFEWIEANIEALNGCDAQALAEAVKRSCEIKASVVAADEREG
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEEEEECCCCCC
GLRAILNFGHTFGHAIEAGLGYGEWLHGEAVGCGMVMAADLSVRLGHLDEAARKRLVAVI
CHHHHHHHCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCEEEECCHHHHHHHHHHHHH
EAAHLPVRAPALGAPRYVDLMRVDKKAEAGEIKFILLKRFGDTLITRAPDDAVLKTLDAS
HHHCCCCCCCCCCCCCHHHHHHHCCCCCCCCEEEEEEEHHCCHHEECCCCHHHHHHHHHH
VGA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA