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The map label for this gene is aroK [H]

Identifier: 186477542

GI number: 186477542

Start: 3146469

End: 3147020

Strand: Reverse

Name: aroK [H]

Synonym: Bphy_2794

Alternate gene names: 186477542

Gene position: 3147020-3146469 (Counterclockwise)

Preceding gene: 186477543

Following gene: 186477541

Centisome position: 90.45

GC content: 65.04

Gene sequence:

>552_bases
TTGCAACCGCGGGACGCACACGCCAACGTTTTTTTTGTAGGGCTCATGGGGGCAGGCAAGACCACCGTGGGCCGGGCCGT
GGCGCGCCGGCTGGATCGCCCGTTCTTCGATTCTGACCATGAAATCGAAGCGCGCACGGGTGCGCGCATCCCGGTGATCT
TCGAACTGGAAGGCGAATCGGGCTTCCGCGACCGCGAAGCGCAGGTGATCGCCGATCTCACTGGCCGCGAAAGCATCGTC
CTCGCGACGGGCGGCGGCGCCGTCCTGCGCCCTGAAAACCGAGAGGCGCTGCGCGCGCACGGCATCGTCGTCTATCTGCG
CGCCAATCCGCACGACCTCTGGCTGCGCACGCGCCGCGACAAAAACCGGCCGCTTCTGCAGACGGAAGACCCGAAAGGGC
GCCTCGAAGCACTGTATGAAGTCCGCGATCCGCTCTACCGCGAATGCGCCGACTTCGTGATCGAAACGGGCCGTCCGTCC
GTCAACGGGCTCGTCAATATGGTGCTGATGCAGCTCGAGATGGCGGGCGTCGCCAAGCCTACTGCGTCATAA

Upstream 100 bases:

>100_bases
GCACCACCTGCGGCAGGCGCGCCGGCCGTCAGGCTCGACAAGTCGGGCGCTTTGCCAGTAAGCTGCCGCACGAACTACAC
CGGATTAGCCAGAGGATAAG

Downstream 100 bases:

>100_bases
TGACGAGATGACTGCCATGATTACCGTCAACGTCGAACTGGGCGAGCGCGCCTATCCCATCCATATCGGCGCCGATCTGA
TCGGCAAGAGCGAGCTGTTC

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MQPRDAHANVFFVGLMGAGKTTVGRAVARRLDRPFFDSDHEIEARTGARIPVIFELEGESGFRDREAQVIADLTGRESIV
LATGGGAVLRPENREALRAHGIVVYLRANPHDLWLRTRRDKNRPLLQTEDPKGRLEALYEVRDPLYRECADFVIETGRPS
VNGLVNMVLMQLEMAGVAKPTAS

Sequences:

>Translated_183_residues
MQPRDAHANVFFVGLMGAGKTTVGRAVARRLDRPFFDSDHEIEARTGARIPVIFELEGESGFRDREAQVIADLTGRESIV
LATGGGAVLRPENREALRAHGIVVYLRANPHDLWLRTRRDKNRPLLQTEDPKGRLEALYEVRDPLYRECADFVIETGRPS
VNGLVNMVLMQLEMAGVAKPTAS
>Mature_183_residues
MQPRDAHANVFFVGLMGAGKTTVGRAVARRLDRPFFDSDHEIEARTGARIPVIFELEGESGFRDREAQVIADLTGRESIV
LATGGGAVLRPENREALRAHGIVVYLRANPHDLWLRTRRDKNRPLLQTEDPKGRLEALYEVRDPLYRECADFVIETGRPS
VNGLVNMVLMQLEMAGVAKPTAS

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=166, Percent_Identity=51.8072289156626, Blast_Score=164, Evalue=2e-42,
Organism=Escherichia coli, GI1786587, Length=155, Percent_Identity=38.0645161290323, Blast_Score=90, Evalue=1e-19,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 20376; Mature: 20376

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: PS01128 SHIKIMATE_KINASE ; PS00267 TACHYKININ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPRDAHANVFFVGLMGAGKTTVGRAVARRLDRPFFDSDHEIEARTGARIPVIFELEGES
CCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCEECCCCCCCEEEEEECCCC
GFRDREAQVIADLTGRESIVLATGGGAVLRPENREALRAHGIVVYLRANPHDLWLRTRRD
CCCCCHHEEEEECCCCCEEEEEECCCEEECCCCHHHHHHCCEEEEEECCCCEEEEEECCC
KNRPLLQTEDPKGRLEALYEVRDPLYRECADFVIETGRPSVNGLVNMVLMQLEMAGVAKP
CCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCC
TAS
CCC
>Mature Secondary Structure
MQPRDAHANVFFVGLMGAGKTTVGRAVARRLDRPFFDSDHEIEARTGARIPVIFELEGES
CCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCEECCCCCCCEEEEEECCCC
GFRDREAQVIADLTGRESIVLATGGGAVLRPENREALRAHGIVVYLRANPHDLWLRTRRD
CCCCCHHEEEEECCCCCEEEEEECCCEEECCCCHHHHHHCCEEEEEECCCCEEEEEECCC
KNRPLLQTEDPKGRLEALYEVRDPLYRECADFVIETGRPSVNGLVNMVLMQLEMAGVAKP
CCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCC
TAS
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA