Click here to switch to the map view.

The map label for this gene is trpG [H]

Identifier: 186477447

GI number: 186477447

Start: 3052890

End: 3053477

Strand: Direct

Name: trpG [H]

Synonym: Bphy_2699

Alternate gene names: 186477447

Gene position: 3052890-3053477 (Clockwise)

Preceding gene: 186477446

Following gene: 186477448

Centisome position: 87.75

GC content: 59.69

Gene sequence:

>588_bases
ATGCTGCTGATGATCGACAACTACGACTCGTTCACCTATAACCTGGTCCAGTACTTCGGCGAACTCGGCGAAGACGTTCG
GACTTATCGCAACGACGAGATCACCCTCGATGACATCGCGAAGCTCAGCCCCGAGCGCATCTGCCTGTCGCCGGGACCGA
GCAATCCGCAACACGCGGGCATCACGCTCGACGTGCTGCGTAAATTTTCCGGCAAGTATCCGATACTCGGCGTGTGCCTT
GGCCATCAGGCGATTGGCGAAGCATTCGGCGGCCGCGTCGTGCGCGCGCAGACCATCATGCACGGCAAGGTGAGCCAGAT
CGAAACCGACTGCAAAGGCGTGTTCGCCGACTTGCCGAAGCATTTCACCGTCACGCGCTATCACTCGCTCGCCATCGAAC
GCGAATCGCTGCCCGACTGCCTCGAAGTGTCCGCGTGGACCGACGACGGAGAAATCATGGGCGTGCGTCATAAGACGCTC
GCCGTCGAAGGCGTGCAGTTCCATCCTGAATCGATTCTGTCGGAACATGGCCACGCGTTGCTCGAAAACTTCGTGAAGCA
GTCGAAAACCGCGGCACGCAGCGCCTGA

Upstream 100 bases:

>100_bases
ATCCGAATGGCAAGAGACGGAGAACAAGGCGCGCGCCGTGCTGCGCGCCGCCGAGCAGGTCCAAGACGGCCTCGATAGCG
ACTTCTGACGGAGACTGACC

Downstream 100 bases:

>100_bases
ATATAAGAGGAGACGTCACCATGATTACGCCACAGGAAGCGCTGCAACGCACGATCGAGCATCGCGAGATTTTCCACGAC
GAGATGCTGCACCTGATGCG

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amido-transferase [H]

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MLLMIDNYDSFTYNLVQYFGELGEDVRTYRNDEITLDDIAKLSPERICLSPGPSNPQHAGITLDVLRKFSGKYPILGVCL
GHQAIGEAFGGRVVRAQTIMHGKVSQIETDCKGVFADLPKHFTVTRYHSLAIERESLPDCLEVSAWTDDGEIMGVRHKTL
AVEGVQFHPESILSEHGHALLENFVKQSKTAARSA

Sequences:

>Translated_195_residues
MLLMIDNYDSFTYNLVQYFGELGEDVRTYRNDEITLDDIAKLSPERICLSPGPSNPQHAGITLDVLRKFSGKYPILGVCL
GHQAIGEAFGGRVVRAQTIMHGKVSQIETDCKGVFADLPKHFTVTRYHSLAIERESLPDCLEVSAWTDDGEIMGVRHKTL
AVEGVQFHPESILSEHGHALLENFVKQSKTAARSA
>Mature_195_residues
MLLMIDNYDSFTYNLVQYFGELGEDVRTYRNDEITLDDIAKLSPERICLSPGPSNPQHAGITLDVLRKFSGKYPILGVCL
GHQAIGEAFGGRVVRAQTIMHGKVSQIETDCKGVFADLPKHFTVTRYHSLAIERESLPDCLEVSAWTDDGEIMGVRHKTL
AVEGVQFHPESILSEHGHALLENFVKQSKTAARSA

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=187, Percent_Identity=60.427807486631, Blast_Score=246, Evalue=6e-67,
Organism=Escherichia coli, GI1787517, Length=191, Percent_Identity=43.455497382199, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI1786215, Length=157, Percent_Identity=26.7515923566879, Blast_Score=64, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6322638, Length=188, Percent_Identity=50.531914893617, Blast_Score=206, Evalue=3e-54,
Organism=Saccharomyces cerevisiae, GI6324361, Length=211, Percent_Identity=36.0189573459716, Blast_Score=92, Evalue=7e-20,
Organism=Drosophila melanogaster, GI281365319, Length=118, Percent_Identity=33.0508474576271, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 21658; Mature: 21658

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLMIDNYDSFTYNLVQYFGELGEDVRTYRNDEITLDDIAKLSPERICLSPGPSNPQHAG
CEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEECCCCCCCCCCC
ITLDVLRKFSGKYPILGVCLGHQAIGEAFGGRVVRAQTIMHGKVSQIETDCKGVFADLPK
CHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCEEEEHHHHHCCHHHHHHHHHHHHHHCCC
HFTVTRYHSLAIERESLPDCLEVSAWTDDGEIMGVRHKTLAVEGVQFHPESILSEHGHAL
CEEHHHHHHHEECCCCCCCHHEEEEECCCCCEEEEEEHEEEECCCEECHHHHHHHCCHHH
LENFVKQSKTAARSA
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MLLMIDNYDSFTYNLVQYFGELGEDVRTYRNDEITLDDIAKLSPERICLSPGPSNPQHAG
CEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEECCCCCCCCCCC
ITLDVLRKFSGKYPILGVCLGHQAIGEAFGGRVVRAQTIMHGKVSQIETDCKGVFADLPK
CHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCEEEEHHHHHCCHHHHHHHHHHHHHHCCC
HFTVTRYHSLAIERESLPDCLEVSAWTDDGEIMGVRHKTLAVEGVQFHPESILSEHGHAL
CEEHHHHHHHEECCCCCCCHHEEEEECCCCCEEEEEEHEEEECCCEECHHHHHHHCCHHH
LENFVKQSKTAARSA
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2105306; 10984043 [H]