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The map label for this gene is gph [C]

Identifier: 186477445

GI number: 186477445

Start: 3050241

End: 3050963

Strand: Direct

Name: gph [C]

Synonym: Bphy_2697

Alternate gene names: 186477445

Gene position: 3050241-3050963 (Clockwise)

Preceding gene: 186477444

Following gene: 186477446

Centisome position: 87.67

GC content: 63.07

Gene sequence:

>723_bases
ATGGAAGCCACGCCTCGTTACCCCGCTCCCGCGTTCACGGCTGGGAAGATTCGGGCGGCTATCGTCGATCTCGACGGCAC
GATGGTCGATACCGCCGACGACTTCACGGCATCGCTGAACGGCATGCTCGCCCAGTTGGACGCGGAAGAAACCTCGCGCG
AAGAAGTGATCGACTATGTCGGCAAAGGCTCCGAGCATCTGATCCGCAGCGTGCTCGCGCCGCGCTTCGAGGCCGAGCTT
GCGCAATCGCGTTTCGACGAGGCGCTCGCGATCTATCAGGAGGAGTACGCGAAGATCAACGGTCTGCATACGCGGCTCTA
TCCCGACGTCGAAGCTGGCCTGATTGCGCTGCGCAACGTGGGTCTGGAACTCGCGTGCGTGACCAACAAGCCGCACCGCT
TCGCGGAACAACTGCTCGAGCATCACGGGCTGCTGCGCTACTTCAGCGTCGTACTGGGCGGCGACAGCGTCGCGGCAAAG
AAGCCCGATCCGCTGCCGATGCTGACCGCGTGCGAGCGGCTCGGTGTGTCGCCTAAGGAGGCCGTTGCGATCGGCGATTC
GCAGAACGATGCGTTCGCCGGCCGCGCGGCCGGCATGGCGACGCTGACCGTGCCGTATGGCTACAATCATGGCGAGGCTG
TGCAAACCATAAATTCGGATGGTATAGTTGTGTCGCTGTTGGGCGCCGCCAAGGCGATCGCGGCGCACAATGCAGTCACA
TAA

Upstream 100 bases:

>100_bases
GCGGACACATTCGTGGCAGGCTCGGCGATCTTCGGCCATCCCGACTACAAGGCGGTCATCGACAAGATGCGCGGCGCGTT
GGCGTCGGTCGGGCGCTGAT

Downstream 100 bases:

>100_bases
GCAACAGACCGAGTGCCGCCCAAGCAGCACTTAATCATTCGACTTAATAAAGTCTTCCTCATGTTTCTGAATAAAAAACG
GAGTCTGAGCACGATCGACC

Product: phosphoglycolate phosphatase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MEATPRYPAPAFTAGKIRAAIVDLDGTMVDTADDFTASLNGMLAQLDAEETSREEVIDYVGKGSEHLIRSVLAPRFEAEL
AQSRFDEALAIYQEEYAKINGLHTRLYPDVEAGLIALRNVGLELACVTNKPHRFAEQLLEHHGLLRYFSVVLGGDSVAAK
KPDPLPMLTACERLGVSPKEAVAIGDSQNDAFAGRAAGMATLTVPYGYNHGEAVQTINSDGIVVSLLGAAKAIAAHNAVT

Sequences:

>Translated_240_residues
MEATPRYPAPAFTAGKIRAAIVDLDGTMVDTADDFTASLNGMLAQLDAEETSREEVIDYVGKGSEHLIRSVLAPRFEAEL
AQSRFDEALAIYQEEYAKINGLHTRLYPDVEAGLIALRNVGLELACVTNKPHRFAEQLLEHHGLLRYFSVVLGGDSVAAK
KPDPLPMLTACERLGVSPKEAVAIGDSQNDAFAGRAAGMATLTVPYGYNHGEAVQTINSDGIVVSLLGAAKAIAAHNAVT
>Mature_240_residues
MEATPRYPAPAFTAGKIRAAIVDLDGTMVDTADDFTASLNGMLAQLDAEETSREEVIDYVGKGSEHLIRSVLAPRFEAEL
AQSRFDEALAIYQEEYAKINGLHTRLYPDVEAGLIALRNVGLELACVTNKPHRFAEQLLEHHGLLRYFSVVLGGDSVAAK
KPDPLPMLTACERLGVSPKEAVAIGDSQNDAFAGRAAGMATLTVPYGYNHGEAVQTINSDGIVVSLLGAAKAIAAHNAVT

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=226, Percent_Identity=35.3982300884956, Blast_Score=134, Evalue=8e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 25605; Mature: 25605

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEATPRYPAPAFTAGKIRAAIVDLDGTMVDTADDFTASLNGMLAQLDAEETSREEVIDYV
CCCCCCCCCCCCCCCCEEEEEEECCCCEECCCHHHHHHHHHHHHHCCCHHCHHHHHHHHH
GKGSEHLIRSVLAPRFEAELAQSRFDEALAIYQEEYAKINGLHTRLYPDVEAGLIALRNV
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEECCCHHHHHHHHHHC
GLELACVTNKPHRFAEQLLEHHGLLRYFSVVLGGDSVAAKKPDPLPMLTACERLGVSPKE
CEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCHHH
AVAIGDSQNDAFAGRAAGMATLTVPYGYNHGEAVQTINSDGIVVSLLGAAKAIAAHNAVT
EEEECCCCCCCHHHHCCCEEEEEECCCCCCCHHHEEECCCCEEEEHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEATPRYPAPAFTAGKIRAAIVDLDGTMVDTADDFTASLNGMLAQLDAEETSREEVIDYV
CCCCCCCCCCCCCCCCEEEEEEECCCCEECCCHHHHHHHHHHHHHCCCHHCHHHHHHHHH
GKGSEHLIRSVLAPRFEAELAQSRFDEALAIYQEEYAKINGLHTRLYPDVEAGLIALRNV
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEECCCHHHHHHHHHHC
GLELACVTNKPHRFAEQLLEHHGLLRYFSVVLGGDSVAAKKPDPLPMLTACERLGVSPKE
CEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCHHH
AVAIGDSQNDAFAGRAAGMATLTVPYGYNHGEAVQTINSDGIVVSLLGAAKAIAAHNAVT
EEEECCCCCCCHHHHCCCEEEEEECCCCCCCHHHEEECCCCEEEEHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA