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The map label for this gene is rpe [H]

Identifier: 186477444

GI number: 186477444

Start: 3049556

End: 3050239

Strand: Direct

Name: rpe [H]

Synonym: Bphy_2696

Alternate gene names: 186477444

Gene position: 3049556-3050239 (Clockwise)

Preceding gene: 186477441

Following gene: 186477445

Centisome position: 87.65

GC content: 62.87

Gene sequence:

>684_bases
ATGACTCAATTCCGCATCGCTCCGAGCATCCTGTCCGCCGACTTCGCGCGGCTCGGCGAAGAAGTCCGCAACGTCGTTGC
CGCAGGCGCCGACTGGATCCACTTCGATGTGATGGACAACCACTATGTCCCGAACCTGACGATCGGCCCGCTCGTATGCG
AAGCGATCCGCCCGCACGTGCAGGTGCCCATCGACGTGCATCTGATGGTGCGTCCCGTCGACCGCATCGTCCCCGACTTC
GCGAAGGCCGGCGCGAACGTGATCAGCTTCCACCCGGAAGGATCGGACCATATCGACCGCACGCTGTCGCTGATTCGCGA
TCACGGCTGCAAGGCGGGCCTCGTGTTCAATCCCGCGACACCGCTCAACTACCTCGATCACGTGATGGACAAGCTGGACC
TCGTGCTCATCATGTCGGTGAATCCGGGCTTCGGCGGACAGTCGTTCATTCCCGAGGCGCTGAACAAGCTGCGCGAAGCA
CGCGCGAAAATCAACGCTTACAAGGAAAAGACCGGCCGCGAGATTCACCTCGAAGTGGACGGCGGCGTGAAGGTCGACAA
CATCGCGGAAATCGCGGCAGCGGGCGCGGACACATTCGTGGCAGGCTCGGCGATCTTCGGCCATCCCGACTACAAGGCGG
TCATCGACAAGATGCGCGGCGCGTTGGCGTCGGTCGGGCGCTGA

Upstream 100 bases:

>100_bases
GAAGATTGCGCCGGATACGCCGCGCCGGGCGCATGCACCAGGCCGCGGCGCGCCACCCAGCGCTAAAATAGCGTTTTTCG
TCTCCCGCCCCACCCTCGCC

Downstream 100 bases:

>100_bases
TATGGAAGCCACGCCTCGTTACCCCGCTCCCGCGTTCACGGCTGGGAAGATTCGGGCGGCTATCGTCGATCTCGACGGCA
CGATGGTCGATACCGCCGAC

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MTQFRIAPSILSADFARLGEEVRNVVAAGADWIHFDVMDNHYVPNLTIGPLVCEAIRPHVQVPIDVHLMVRPVDRIVPDF
AKAGANVISFHPEGSDHIDRTLSLIRDHGCKAGLVFNPATPLNYLDHVMDKLDLVLIMSVNPGFGGQSFIPEALNKLREA
RAKINAYKEKTGREIHLEVDGGVKVDNIAEIAAAGADTFVAGSAIFGHPDYKAVIDKMRGALASVGR

Sequences:

>Translated_227_residues
MTQFRIAPSILSADFARLGEEVRNVVAAGADWIHFDVMDNHYVPNLTIGPLVCEAIRPHVQVPIDVHLMVRPVDRIVPDF
AKAGANVISFHPEGSDHIDRTLSLIRDHGCKAGLVFNPATPLNYLDHVMDKLDLVLIMSVNPGFGGQSFIPEALNKLREA
RAKINAYKEKTGREIHLEVDGGVKVDNIAEIAAAGADTFVAGSAIFGHPDYKAVIDKMRGALASVGR
>Mature_226_residues
TQFRIAPSILSADFARLGEEVRNVVAAGADWIHFDVMDNHYVPNLTIGPLVCEAIRPHVQVPIDVHLMVRPVDRIVPDFA
KAGANVISFHPEGSDHIDRTLSLIRDHGCKAGLVFNPATPLNYLDHVMDKLDLVLIMSVNPGFGGQSFIPEALNKLREAR
AKINAYKEKTGREIHLEVDGGVKVDNIAEIAAAGADTFVAGSAIFGHPDYKAVIDKMRGALASVGR

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=225, Percent_Identity=37.7777777777778, Blast_Score=157, Evalue=8e-39,
Organism=Homo sapiens, GI219879828, Length=217, Percent_Identity=37.3271889400922, Blast_Score=147, Evalue=6e-36,
Organism=Homo sapiens, GI24307923, Length=180, Percent_Identity=30.5555555555556, Blast_Score=94, Evalue=1e-19,
Organism=Escherichia coli, GI1789788, Length=226, Percent_Identity=71.2389380530973, Blast_Score=335, Evalue=1e-93,
Organism=Escherichia coli, GI1790523, Length=209, Percent_Identity=39.2344497607655, Blast_Score=159, Evalue=1e-40,
Organism=Escherichia coli, GI1790754, Length=211, Percent_Identity=30.3317535545024, Blast_Score=98, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17552948, Length=222, Percent_Identity=40.5405405405405, Blast_Score=154, Evalue=4e-38,
Organism=Saccharomyces cerevisiae, GI6322341, Length=232, Percent_Identity=37.9310344827586, Blast_Score=158, Evalue=6e-40,
Organism=Drosophila melanogaster, GI24586301, Length=223, Percent_Identity=34.9775784753363, Blast_Score=142, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 24663; Mature: 24531

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQFRIAPSILSADFARLGEEVRNVVAAGADWIHFDVMDNHYVPNLTIGPLVCEAIRPHV
CCCEECCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCE
QVPIDVHLMVRPVDRIVPDFAKAGANVISFHPEGSDHIDRTLSLIRDHGCKAGLVFNPAT
ECCEEEEEEEECHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCEEECCCC
PLNYLDHVMDKLDLVLIMSVNPGFGGQSFIPEALNKLREARAKINAYKEKTGREIHLEVD
HHHHHHHHHHHHCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
GGVKVDNIAEIAAAGADTFVAGSAIFGHPDYKAVIDKMRGALASVGR
CCCCHHHHHHHHHCCCCHHEECCEEECCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TQFRIAPSILSADFARLGEEVRNVVAAGADWIHFDVMDNHYVPNLTIGPLVCEAIRPHV
CCEECCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCE
QVPIDVHLMVRPVDRIVPDFAKAGANVISFHPEGSDHIDRTLSLIRDHGCKAGLVFNPAT
ECCEEEEEEEECHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCEEECCCC
PLNYLDHVMDKLDLVLIMSVNPGFGGQSFIPEALNKLREARAKINAYKEKTGREIHLEVD
HHHHHHHHHHHHCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
GGVKVDNIAEIAAAGADTFVAGSAIFGHPDYKAVIDKMRGALASVGR
CCCCHHHHHHHHHCCCCHHEECCEEECCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]