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The map label for this gene is paaK [H]

Identifier: 186477441

GI number: 186477441

Start: 3046143

End: 3047447

Strand: Direct

Name: paaK [H]

Synonym: Bphy_2693

Alternate gene names: 186477441

Gene position: 3046143-3047447 (Clockwise)

Preceding gene: 186477440

Following gene: 186477444

Centisome position: 87.55

GC content: 62.76

Gene sequence:

>1305_bases
ATGACTACCCAGCTCCCGCTCGATCCGATCGAAAAGGCGAGCCGCGACGAGCTCGCCGGGCTTCAACTCGAACGGCTGAA
ATGGTCGCTCGCGCACGCGTATGAAAATTCGCCTGTCTACCGACGTAAATTCGACGAAGCGGGCGTACATCCGGCCGAGC
TGAAGACGCTGTCCGACCTGTCACGCTTCCCGTTCACCACGAAGAAGGATCTTCGTGATAACTACCCGTTCGGCCTGTTC
GCCGTACCGCAAGAACGGATCTCGCGAATCCACGCGTCGTCGGGCACCACGGGCAAGCCAACCGTCGTCGGTTATACGGC
GCGCGATATCGACAACTGGGCGAACCTGGTCGCGCGCTCTATCCGCGCAGCAGGCGCGCGACGTGGCGACAAGGTACACG
TGAGCTACGGCTACGGCCTCTTTACGGGCGGTCTCGGCGCGCACTACGGCGCCGAGCGCGCGGGCCTGACCGTCATTCCG
TTTGGCGGCGGGCAAACCGAGAAGCAGGTGCAACTGATCCAGGACTTCCGCCCCGACATCATCATGGTGACGCCGAGCTA
TATGCTCTCCATTGCCGATGAGCTGGAACGCCAAGGCGTCAATCCCAGAGATTGCTCGCTGCGCATCGGCATCTTTGGTG
CGGAGCCGTGGACGAACGACATGCGCCGCGCGATCGAAGAACGGATGGGCATCGACGCCGTCGACATCTACGGTCTGTCG
GAGGTGATGGGGCCGGGCGTGGCGTCGGAATGCGTCGAAACCAAGGACGGCCCGACGATCTGGGAAGATCACTTTTATCC
CGAGATCATCGATCCCGAGACAGGCGACGTGCTGCCAGACGGCGAACTGGGCGAACTCGTGTTCACATCGCTGACGAAGG
AAGCGTTGCCTATCATCCGTTATCGCACGCGCGATCTCACGCGTCTGCTGCCCGGCACCGCGCGGACGATGCGTCGAATG
GAAAAGATCACCGGCCGCTCGGACGACATGATGATCATCCGCGGCGTCAATGTGTTCCCGACGCAGATCGAAGAGTTGCT
GCTCAAGCAGCACGCGCTCGCGCCGCACTACCAGATCGTGCTCACCAAGGAAGGCCCGCTGGACGTGATGACACTGAACG
TCGAACCCTGTCCGGAAACCGCGCCGGACACGGTCGCGCTGACGGCGGCGAAACAGGCGCTGGCTTACGACATCAAGGCG
CTGATCGGCGTGACGGCGAACGTGGTGCTGCTCGGCGTGAACGGCATCGAGCGTTCGGTGGGCAAGGCGCGTCGCGTGAT
CGACAAGCGCAGGGCAGGCGCCTAA

Upstream 100 bases:

>100_bases
ACGGTGATCCCCGTCGACAACTGACGGGCAGCCTCACCCTTTCAAGAAATTGCGTCGCCTTTCGCGCGGCATCCTATTCT
GAAAAGCAAGGAGACATTCG

Downstream 100 bases:

>100_bases
GCGTCAATGCCGCAAACTGCCGGCTGACAAAAACGAAAGCCCGACGGCGGTGATGACAGCCGTCGGGCTTTCCAGTTCAG
GCAACGGCTGAAGCGCGCCC

Product: phenylacetate-CoA ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MTTQLPLDPIEKASRDELAGLQLERLKWSLAHAYENSPVYRRKFDEAGVHPAELKTLSDLSRFPFTTKKDLRDNYPFGLF
AVPQERISRIHASSGTTGKPTVVGYTARDIDNWANLVARSIRAAGARRGDKVHVSYGYGLFTGGLGAHYGAERAGLTVIP
FGGGQTEKQVQLIQDFRPDIIMVTPSYMLSIADELERQGVNPRDCSLRIGIFGAEPWTNDMRRAIEERMGIDAVDIYGLS
EVMGPGVASECVETKDGPTIWEDHFYPEIIDPETGDVLPDGELGELVFTSLTKEALPIIRYRTRDLTRLLPGTARTMRRM
EKITGRSDDMMIIRGVNVFPTQIEELLLKQHALAPHYQIVLTKEGPLDVMTLNVEPCPETAPDTVALTAAKQALAYDIKA
LIGVTANVVLLGVNGIERSVGKARRVIDKRRAGA

Sequences:

>Translated_434_residues
MTTQLPLDPIEKASRDELAGLQLERLKWSLAHAYENSPVYRRKFDEAGVHPAELKTLSDLSRFPFTTKKDLRDNYPFGLF
AVPQERISRIHASSGTTGKPTVVGYTARDIDNWANLVARSIRAAGARRGDKVHVSYGYGLFTGGLGAHYGAERAGLTVIP
FGGGQTEKQVQLIQDFRPDIIMVTPSYMLSIADELERQGVNPRDCSLRIGIFGAEPWTNDMRRAIEERMGIDAVDIYGLS
EVMGPGVASECVETKDGPTIWEDHFYPEIIDPETGDVLPDGELGELVFTSLTKEALPIIRYRTRDLTRLLPGTARTMRRM
EKITGRSDDMMIIRGVNVFPTQIEELLLKQHALAPHYQIVLTKEGPLDVMTLNVEPCPETAPDTVALTAAKQALAYDIKA
LIGVTANVVLLGVNGIERSVGKARRVIDKRRAGA
>Mature_433_residues
TTQLPLDPIEKASRDELAGLQLERLKWSLAHAYENSPVYRRKFDEAGVHPAELKTLSDLSRFPFTTKKDLRDNYPFGLFA
VPQERISRIHASSGTTGKPTVVGYTARDIDNWANLVARSIRAAGARRGDKVHVSYGYGLFTGGLGAHYGAERAGLTVIPF
GGGQTEKQVQLIQDFRPDIIMVTPSYMLSIADELERQGVNPRDCSLRIGIFGAEPWTNDMRRAIEERMGIDAVDIYGLSE
VMGPGVASECVETKDGPTIWEDHFYPEIIDPETGDVLPDGELGELVFTSLTKEALPIIRYRTRDLTRLLPGTARTMRRME
KITGRSDDMMIIRGVNVFPTQIEELLLKQHALAPHYQIVLTKEGPLDVMTLNVEPCPETAPDTVALTAAKQALAYDIKAL
IGVTANVVLLGVNGIERSVGKARRVIDKRRAGA

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=436, Percent_Identity=65.3669724770642, Blast_Score=593, Evalue=1e-171,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 47969; Mature: 47837

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTQLPLDPIEKASRDELAGLQLERLKWSLAHAYENSPVYRRKFDEAGVHPAELKTLSDL
CCCCCCCCHHHHCCHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHH
SRFPFTTKKDLRDNYPFGLFAVPQERISRIHASSGTTGKPTVVGYTARDIDNWANLVARS
HHCCCCCHHHHCCCCCEEEEECCHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHH
IRAAGARRGDKVHVSYGYGLFTGGLGAHYGAERAGLTVIPFGGGQTEKQVQLIQDFRPDI
HHHHCCCCCCEEEEEECCCEEECCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCE
IMVTPSYMLSIADELERQGVNPRDCSLRIGIFGAEPWTNDMRRAIEERMGIDAVDIYGLS
EEECHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCEEECCCHH
EVMGPGVASECVETKDGPTIWEDHFYPEIIDPETGDVLPDGELGELVFTSLTKEALPIIR
HHHCCCHHHHHHCCCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
YRTRDLTRLLPGTARTMRRMEKITGRSDDMMIIRGVNVFPTQIEELLLKQHALAPHYQIV
HHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEE
LTKEGPLDVMTLNVEPCPETAPDTVALTAAKQALAYDIKALIGVTANVVLLGVNGIERSV
EECCCCEEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHH
GKARRVIDKRRAGA
HHHHHHHHHHCCCC
>Mature Secondary Structure 
TTQLPLDPIEKASRDELAGLQLERLKWSLAHAYENSPVYRRKFDEAGVHPAELKTLSDL
CCCCCCCHHHHCCHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHH
SRFPFTTKKDLRDNYPFGLFAVPQERISRIHASSGTTGKPTVVGYTARDIDNWANLVARS
HHCCCCCHHHHCCCCCEEEEECCHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHH
IRAAGARRGDKVHVSYGYGLFTGGLGAHYGAERAGLTVIPFGGGQTEKQVQLIQDFRPDI
HHHHCCCCCCEEEEEECCCEEECCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCE
IMVTPSYMLSIADELERQGVNPRDCSLRIGIFGAEPWTNDMRRAIEERMGIDAVDIYGLS
EEECHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCEEECCCHH
EVMGPGVASECVETKDGPTIWEDHFYPEIIDPETGDVLPDGELGELVFTSLTKEALPIIR
HHHCCCHHHHHHCCCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
YRTRDLTRLLPGTARTMRRMEKITGRSDDMMIIRGVNVFPTQIEELLLKQHALAPHYQIV
HHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEE
LTKEGPLDVMTLNVEPCPETAPDTVALTAAKQALAYDIKALIGVTANVVLLGVNGIERSV
EECCCCEEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHH
GKARRVIDKRRAGA
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]