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The map label for this gene is exuR [H]

Identifier: 186477345

GI number: 186477345

Start: 2934810

End: 2935502

Strand: Direct

Name: exuR [H]

Synonym: Bphy_2597

Alternate gene names: 186477345

Gene position: 2934810-2935502 (Clockwise)

Preceding gene: 186477341

Following gene: 186477348

Centisome position: 84.35

GC content: 57.58

Gene sequence:

>693_bases
ATGAAAAACGTCCCGCATACCGTCACTGACGCTGCCATCGCGACGATCCGCGAGAGGATCGAAGGCGGCGCTTATCCTGT
TGGGAGCCTGTTGCCGGCGCAGCGGCAGTTGTCGGAAGAAATGGACATCAGCCGGGCGTCCCTGCGTGAGGCGCTATCGA
CGCTCGAAGCGCTCGGCATGCTGACGATTCGCCCTGGGAAGGGCGTGTATGTGCAATCGACGAAGGCGTCGTCCGCCCAT
CCGTGGCGGTTTGCGGATCAGTCGTCGTTGCCGGATACGTATCAGATGCGGTTTGCGCTGGAGGGTTTTGTCGCGAGAAT
GGCTGCGCTCGCTATTGGCGACGACGATGTTGTATGGTTTGAAGACAATATCGCTGCTTTGCAGGTCGCATTGACCAATG
GCGATCTCGACGATGCCGCTCAGCTCGATTTCGACTTTCATATGCGCATCGTGGCGATTGCTGGCAATGCTGCCATCGAG
TCGATCTTGCGCAGCAGCGCTGACATTATGAAAGAGAGTCAGCGGATGCCGTTTTATCGACGCGAGCTCGTGCTGTCCAC
TTATCACGAGCATCGCGAGATTCTTGACGCGCTGAAGGCGCGTAATCCTCACGCTGCCGGGCTTGCTATCGAGAAGCACA
TTGCTAATGCTGCCCAACGAGCCGGGGTTTATTTTCCTACGCCACAGGTGTGA

Upstream 100 bases:

>100_bases
GGCCTTCTTCCGTGCGATTGGCGACAGAATACGGTTTGCACGTTCGGCACGAAGCCGTTCTAGAATACTGGTCAGACCGC
ACCGAACCGCCGCCGAGATC

Downstream 100 bases:

>100_bases
GTTTCTTTGTCCGCGACGCAGTCGCCATTCCGGGGTTTCGCTGCGGTTTTTTCGCGGGCATCCGCGTTGTGTTATCGGGT
TGCCAGGGTTGCCAAGGTTG

Product: GntR domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MKNVPHTVTDAAIATIRERIEGGAYPVGSLLPAQRQLSEEMDISRASLREALSTLEALGMLTIRPGKGVYVQSTKASSAH
PWRFADQSSLPDTYQMRFALEGFVARMAALAIGDDDVVWFEDNIAALQVALTNGDLDDAAQLDFDFHMRIVAIAGNAAIE
SILRSSADIMKESQRMPFYRRELVLSTYHEHREILDALKARNPHAAGLAIEKHIANAAQRAGVYFPTPQV

Sequences:

>Translated_230_residues
MKNVPHTVTDAAIATIRERIEGGAYPVGSLLPAQRQLSEEMDISRASLREALSTLEALGMLTIRPGKGVYVQSTKASSAH
PWRFADQSSLPDTYQMRFALEGFVARMAALAIGDDDVVWFEDNIAALQVALTNGDLDDAAQLDFDFHMRIVAIAGNAAIE
SILRSSADIMKESQRMPFYRRELVLSTYHEHREILDALKARNPHAAGLAIEKHIANAAQRAGVYFPTPQV
>Mature_230_residues
MKNVPHTVTDAAIATIRERIEGGAYPVGSLLPAQRQLSEEMDISRASLREALSTLEALGMLTIRPGKGVYVQSTKASSAH
PWRFADQSSLPDTYQMRFALEGFVARMAALAIGDDDVVWFEDNIAALQVALTNGDLDDAAQLDFDFHMRIVAIAGNAAIE
SILRSSADIMKESQRMPFYRRELVLSTYHEHREILDALKARNPHAAGLAIEKHIANAAQRAGVYFPTPQV

Specific function: Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the exuT, uxaCA and uxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082208, Length=223, Percent_Identity=26.9058295964126, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1786303, Length=210, Percent_Identity=32.3809523809524, Blast_Score=87, Evalue=6e-19,
Organism=Escherichia coli, GI1790780, Length=223, Percent_Identity=28.2511210762332, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1789353, Length=225, Percent_Identity=28, Blast_Score=67, Evalue=7e-13,
Organism=Escherichia coli, GI1790032, Length=224, Percent_Identity=26.7857142857143, Blast_Score=67, Evalue=7e-13,
Organism=Escherichia coli, GI1787821, Length=185, Percent_Identity=27.027027027027, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 25304; Mature: 25304

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNVPHTVTDAAIATIRERIEGGAYPVGSLLPAQRQLSEEMDISRASLREALSTLEALGM
CCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LTIRPGKGVYVQSTKASSAHPWRFADQSSLPDTYQMRFALEGFVARMAALAIGDDDVVWF
EEECCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
EDNIAALQVALTNGDLDDAAQLDFDFHMRIVAIAGNAAIESILRSSADIMKESQRMPFYR
ECCEEEEEEEEECCCCCCHHHCCCEEEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCHHH
RELVLSTYHEHREILDALKARNPHAAGLAIEKHIANAAQRAGVYFPTPQV
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKNVPHTVTDAAIATIRERIEGGAYPVGSLLPAQRQLSEEMDISRASLREALSTLEALGM
CCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LTIRPGKGVYVQSTKASSAHPWRFADQSSLPDTYQMRFALEGFVARMAALAIGDDDVVWF
EEECCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
EDNIAALQVALTNGDLDDAAQLDFDFHMRIVAIAGNAAIESILRSSADIMKESQRMPFYR
ECCEEEEEEEEECCCCCCHHHCCCEEEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCHHH
RELVLSTYHEHREILDALKARNPHAAGLAIEKHIANAAQRAGVYFPTPQV
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA