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The map label for this gene is fur [H]

Identifier: 186477341

GI number: 186477341

Start: 2931049

End: 2931477

Strand: Direct

Name: fur [H]

Synonym: Bphy_2593

Alternate gene names: 186477341

Gene position: 2931049-2931477 (Clockwise)

Preceding gene: 186477331

Following gene: 186477345

Centisome position: 84.25

GC content: 56.18

Gene sequence:

>429_bases
ATGACCAATCCAACCGATCTGAAAAATATCGGACTCAAGGCGACCCTACCGCGCCTCAAGATTCTGGAAATCTTTCAGCA
CAGCCCGGTGCGCCATCTGACCGCCGAAGATGTCTACCGCAATCTGCTGCATGAAGAGCTGGATATCGGGCTCGCCACGG
TGTATCGCGTGCTCACGCAGTTCGAGCAGGCAGGTTTGCTGTCGCGTAGCAACTTCGAGTCGGGTAAAGCCGTTTTTGAG
CTGAACGAAGGGACGCACCATGACCATCTGGTGTGTATCGACTGCGGTCTCGTCGAAGAATTTTTCGACCCCGAAATCGA
AAATCGCCAGCAGGCGATCGCGAAAGAACGCGGCTTCAAGCTCCAGGAACACGCGCTCGCGCTCTACGGCGCGTGCACGA
AGGACAAGTGTCCGCACCGCAAGCATTGA

Upstream 100 bases:

>100_bases
TGCGGGCTTACCGAGCCGCGCGTGTTTCCGTGTAAGATGACCTGAACAGCAATTCACATTACTATTAGAACCCCGCATTG
TACTCTAGGGATCCCTTGCC

Downstream 100 bases:

>100_bases
CGCATTTTCAGTAAGAAGCAGAAAGGCCCGGCTGATGAGAATCAACCGGGCCTTTTGCTTTCCCTCGCTTACCGGGAGGC
AACGACGCGACTAGACAGCA

Product: ferric uptake regulator family protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MTNPTDLKNIGLKATLPRLKILEIFQHSPVRHLTAEDVYRNLLHEELDIGLATVYRVLTQFEQAGLLSRSNFESGKAVFE
LNEGTHHDHLVCIDCGLVEEFFDPEIENRQQAIAKERGFKLQEHALALYGACTKDKCPHRKH

Sequences:

>Translated_142_residues
MTNPTDLKNIGLKATLPRLKILEIFQHSPVRHLTAEDVYRNLLHEELDIGLATVYRVLTQFEQAGLLSRSNFESGKAVFE
LNEGTHHDHLVCIDCGLVEEFFDPEIENRQQAIAKERGFKLQEHALALYGACTKDKCPHRKH
>Mature_141_residues
TNPTDLKNIGLKATLPRLKILEIFQHSPVRHLTAEDVYRNLLHEELDIGLATVYRVLTQFEQAGLLSRSNFESGKAVFEL
NEGTHHDHLVCIDCGLVEEFFDPEIENRQQAIAKERGFKLQEHALALYGACTKDKCPHRKH

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Regulator for biosynthesis of the siderophore alcaligin E [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=140, Percent_Identity=54.2857142857143, Blast_Score=157, Evalue=4e-40,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16232; Mature: 16101

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNPTDLKNIGLKATLPRLKILEIFQHSPVRHLTAEDVYRNLLHEELDIGLATVYRVLTQ
CCCCCCHHHCCCCCCCCHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHCCCHHHHHHHHHH
FEQAGLLSRSNFESGKAVFELNEGTHHDHLVCIDCGLVEEFFDPEIENRQQAIAKERGFK
HHHHCCCCCCCCCCCCEEEEECCCCCCCCEEEEECCHHHHHCCCCCCHHHHHHHHHHCCC
LQEHALALYGACTKDKCPHRKH
HHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TNPTDLKNIGLKATLPRLKILEIFQHSPVRHLTAEDVYRNLLHEELDIGLATVYRVLTQ
CCCCCHHHCCCCCCCCHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHCCCHHHHHHHHHH
FEQAGLLSRSNFESGKAVFELNEGTHHDHLVCIDCGLVEEFFDPEIENRQQAIAKERGFK
HHHHCCCCCCCCCCCCEEEEECCCCCCCCEEEEECCHHHHHCCCCCCHHHHHHHHHHCCC
LQEHALALYGACTKDKCPHRKH
HHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA