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The map label for this gene is exbB [H]

Identifier: 186477338

GI number: 186477338

Start: 2928266

End: 2929018

Strand: Reverse

Name: exbB [H]

Synonym: Bphy_2590

Alternate gene names: 186477338

Gene position: 2929018-2928266 (Counterclockwise)

Preceding gene: 186477339

Following gene: 186477337

Centisome position: 84.19

GC content: 66.93

Gene sequence:

>753_bases
ATGGCAAACACCGGCATCATCCACTATCTGCAAACCAGCGATGCCATCACGCATGGCGTCGCCTATGTGCTGCTGGCGAT
GTCGATTGCGAGCTGGTGCTTCCTGATCGTCAAAAGCTGGATGCTGAGCCGCGCCAAGCGGCAAGGGCCGCGCGCTGTCG
CGCGGTTCTGGCTGGCGCCGACGCTGGCCGAAGGCGTGGCGACACTGCGTCTCGCGGATCGCGAACGCATCTTTTCCCCG
CTGGCAGAAGCGGCGCTGAAGGCTTCGGAAGTCGAGACGCCGGGTGCGCTGCTCGCGCGCGTCGAGCGTAGTGAACGCGT
GCTGCGGGCGCTGCGCCAGGCGTTGCACCGCTCGCAGCGCCGGCTGGAATTCGGCCAGGTGCTGCTCGCGTCGATAGGCA
GCACGGCGCCGTTCGTCGGGCTGCTCGGCACCGTGTGGGGCATTTATCACGCGCTCGGCAGCATCGCGCAGAGCGGTCAG
GCAATGATCGAAAACGTCGCGGGGCCCGTCGGGGAGGCGCTCATCATGACGGCATTCGGTCTCGTCGTCGCGATTCCTGC
CGTGCTTGCGTATAACGTGCTTGGACGGATGGTGCGGCAGGTGTCGGAAGATCTCGACGGCTTCGCCCACGATCTGCACG
CGTACGTGTGCGCGCCTGCAGATGAAGCGCACGGCGGCGGGCGCGGCGATTTGCGCGACAACCCGCGCGATGCCCAAGGC
AGCGCACGCTCGCCTGCGCGGACGCAGGCCTAA

Upstream 100 bases:

>100_bases
GCCTGTTCGACATGCAGGACGTGCTGGGCTTGCGTTAAGCCCTGCATCGATCACGTTTTCACTCGCCGGGGCGCGACGGC
CCGGCGACCGGCGAGGTCCG

Downstream 100 bases:

>100_bases
CGCACACACGCAAGCACACACGCAAGCACACAACCGGCGAGAGCGAGGCACGGCACATGGCATTCGGCGGACTCGACAGG
CACAAGACGGCGGCGCCGAT

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MANTGIIHYLQTSDAITHGVAYVLLAMSIASWCFLIVKSWMLSRAKRQGPRAVARFWLAPTLAEGVATLRLADRERIFSP
LAEAALKASEVETPGALLARVERSERVLRALRQALHRSQRRLEFGQVLLASIGSTAPFVGLLGTVWGIYHALGSIAQSGQ
AMIENVAGPVGEALIMTAFGLVVAIPAVLAYNVLGRMVRQVSEDLDGFAHDLHAYVCAPADEAHGGGRGDLRDNPRDAQG
SARSPARTQA

Sequences:

>Translated_250_residues
MANTGIIHYLQTSDAITHGVAYVLLAMSIASWCFLIVKSWMLSRAKRQGPRAVARFWLAPTLAEGVATLRLADRERIFSP
LAEAALKASEVETPGALLARVERSERVLRALRQALHRSQRRLEFGQVLLASIGSTAPFVGLLGTVWGIYHALGSIAQSGQ
AMIENVAGPVGEALIMTAFGLVVAIPAVLAYNVLGRMVRQVSEDLDGFAHDLHAYVCAPADEAHGGGRGDLRDNPRDAQG
SARSPARTQA
>Mature_249_residues
ANTGIIHYLQTSDAITHGVAYVLLAMSIASWCFLIVKSWMLSRAKRQGPRAVARFWLAPTLAEGVATLRLADRERIFSPL
AEAALKASEVETPGALLARVERSERVLRALRQALHRSQRRLEFGQVLLASIGSTAPFVGLLGTVWGIYHALGSIAQSGQA
MIENVAGPVGEALIMTAFGLVVAIPAVLAYNVLGRMVRQVSEDLDGFAHDLHAYVCAPADEAHGGGRGDLRDNPRDAQGS
ARSPARTQA

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=236, Percent_Identity=30.5084745762712, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1789381, Length=190, Percent_Identity=32.6315789473684, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 26802; Mature: 26671

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANTGIIHYLQTSDAITHGVAYVLLAMSIASWCFLIVKSWMLSRAKRQGPRAVARFWLAP
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
TLAEGVATLRLADRERIFSPLAEAALKASEVETPGALLARVERSERVLRALRQALHRSQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLEFGQVLLASIGSTAPFVGLLGTVWGIYHALGSIAQSGQAMIENVAGPVGEALIMTAFG
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LVVAIPAVLAYNVLGRMVRQVSEDLDGFAHDLHAYVCAPADEAHGGGRGDLRDNPRDAQG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCCCC
SARSPARTQA
CCCCCCCCCC
>Mature Secondary Structure 
ANTGIIHYLQTSDAITHGVAYVLLAMSIASWCFLIVKSWMLSRAKRQGPRAVARFWLAP
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
TLAEGVATLRLADRERIFSPLAEAALKASEVETPGALLARVERSERVLRALRQALHRSQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLEFGQVLLASIGSTAPFVGLLGTVWGIYHALGSIAQSGQAMIENVAGPVGEALIMTAFG
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LVVAIPAVLAYNVLGRMVRQVSEDLDGFAHDLHAYVCAPADEAHGGGRGDLRDNPRDAQG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCCCC
SARSPARTQA
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9371459 [H]