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The map label for this gene is gntP [H]

Identifier: 186477326

GI number: 186477326

Start: 2898583

End: 2899944

Strand: Reverse

Name: gntP [H]

Synonym: Bphy_2578

Alternate gene names: 186477326

Gene position: 2899944-2898583 (Counterclockwise)

Preceding gene: 186477327

Following gene: 186477325

Centisome position: 83.35

GC content: 62.11

Gene sequence:

>1362_bases
ATGGAAGCTGTCCACGGCAGCATGCTGCTGATCTACGCCGTGATTGCCATTGCAGTGCTGATCCTCATGATCACGCGCTT
CAAGGTCTATCCGTTCCTCGTCCTTATCATCGTCTCGTTGCTGCTCGGCCTTGCCGTCGGCATGCCGGCGGGGACGATCG
TGAAATCGTTCGAGACAGGTAACGGCAACACGCTGGGCCATATTGCGATCGTCGTCGGTCTTGGCACGATGCTCGGCAAG
ATGATGGCCGAATCGGGCGGCGCCGAGCGCGTCGCCACGACGTTGATCAACTGGTTCGGTGAGAAAAACATTCACTGGGC
GATGATGTTCGTCGCGATCATCGTCGGCTTGCCGGTGTTCTTCGAAGTCGGCTTCGTGCTGCTGATTCCGATCGCCTTCA
ACGTCGCGAAGCGCACGGGCAAATCGCTGCTGCTGATCGGCCTGCCGATGGTCGCGGGCCTGTCCGTCGTGCACGGTCTG
ATTCCGCCGCACCCGGCCGCGCTGCTCGCCGTGCAGGCGTATCACGCGGATATCGGTCGCACGATCGCGTACGGTCTGAT
CGTCGGCGTGCCGACGGCGATCGTCGCCGGTCCGCTGTTCGCGCTGCTGATCCATCGTCACATCAAGCTGGCGGCGAACA
ATCCGCTTGCCGCGCAGTTCATTGATACGGAGCATAAAGAGGGCACGCGCGATCTGCCGGGCTTCGGGATCACGCTGTTC
ACGATTTTGCTGCCCGTGATTCTGATGCTGGTCGGCAGCTGGGCGGATCTCGTGTTCGCGCCGAAGACGACCGCGAACGA
TCTGCTGCGATTCATCGGTACATCCGACGTCGCGCTGCTGATCGCCGTGCTCGTCAGCTTCTGGACGTTTGGCGCGAAAC
GCGGCTTCAATCGCGAGCAGATTCAGAAGTTTTGCGGCGACTGTCTGGCGCCGATCGCGGGCATTACGCTGATCGTCGGT
GCGGGCGGTGGTTTCGGCCGCGTGCTGATGGATAGCGGCATCTCGAAGGAAATCGTCGCGACGGCAACGGCTGCGCATCT
GTCGCCGCTGCTGTTCGGCTGGTTCGTCGCCGCGTTGATCCGTCTCGCGACGGGTTCGGCGACGGTCGCGATGACGACGG
CGTGCGGCATCGTCGCGCCGGTTGCGGCGGCGAGCGGCGTGCAGGTCAAGCCTGAGTTGCTGGTGCTGGCGACGGGTTCG
GGCTCGCTGATTTTCTCGCATGTCAACGACGGCGGCTTCTGGCTGATCAAGGAGTATTTCGGCATGACGGTGGGGCAGAC
GTTTCAGACGTGGTCGCTCTGCGAAACCATCATTTCGCTGATGGGTCTGGGTTTGACCTTCGCGTTGGCGGCGGTCCTGT
AA

Upstream 100 bases:

>100_bases
ACGCACCCAATCCTGAGGGCGCTTTCAGCATCCGGAAGCGGGCGAGGTGCCGCAGCACTTTGCAATTCGAACCAACAAAC
CAAAGCAAAGGAGGAGCTTC

Downstream 100 bases:

>100_bases
GGAGTTTCAAATGATTTTGATCGCGATGGGCGTATCGGGCGCCGGCAAGACCCGGATTGGGGAATTGCTGGCTGAGCGGC
TCAAGTGCAGTTTCACCGAC

Product: gluconate transporter

Products: gluconate [Cytoplasm]; L-idonate [Cytoplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MEAVHGSMLLIYAVIAIAVLILMITRFKVYPFLVLIIVSLLLGLAVGMPAGTIVKSFETGNGNTLGHIAIVVGLGTMLGK
MMAESGGAERVATTLINWFGEKNIHWAMMFVAIIVGLPVFFEVGFVLLIPIAFNVAKRTGKSLLLIGLPMVAGLSVVHGL
IPPHPAALLAVQAYHADIGRTIAYGLIVGVPTAIVAGPLFALLIHRHIKLAANNPLAAQFIDTEHKEGTRDLPGFGITLF
TILLPVILMLVGSWADLVFAPKTTANDLLRFIGTSDVALLIAVLVSFWTFGAKRGFNREQIQKFCGDCLAPIAGITLIVG
AGGGFGRVLMDSGISKEIVATATAAHLSPLLFGWFVAALIRLATGSATVAMTTACGIVAPVAAASGVQVKPELLVLATGS
GSLIFSHVNDGGFWLIKEYFGMTVGQTFQTWSLCETIISLMGLGLTFALAAVL

Sequences:

>Translated_453_residues
MEAVHGSMLLIYAVIAIAVLILMITRFKVYPFLVLIIVSLLLGLAVGMPAGTIVKSFETGNGNTLGHIAIVVGLGTMLGK
MMAESGGAERVATTLINWFGEKNIHWAMMFVAIIVGLPVFFEVGFVLLIPIAFNVAKRTGKSLLLIGLPMVAGLSVVHGL
IPPHPAALLAVQAYHADIGRTIAYGLIVGVPTAIVAGPLFALLIHRHIKLAANNPLAAQFIDTEHKEGTRDLPGFGITLF
TILLPVILMLVGSWADLVFAPKTTANDLLRFIGTSDVALLIAVLVSFWTFGAKRGFNREQIQKFCGDCLAPIAGITLIVG
AGGGFGRVLMDSGISKEIVATATAAHLSPLLFGWFVAALIRLATGSATVAMTTACGIVAPVAAASGVQVKPELLVLATGS
GSLIFSHVNDGGFWLIKEYFGMTVGQTFQTWSLCETIISLMGLGLTFALAAVL
>Mature_453_residues
MEAVHGSMLLIYAVIAIAVLILMITRFKVYPFLVLIIVSLLLGLAVGMPAGTIVKSFETGNGNTLGHIAIVVGLGTMLGK
MMAESGGAERVATTLINWFGEKNIHWAMMFVAIIVGLPVFFEVGFVLLIPIAFNVAKRTGKSLLLIGLPMVAGLSVVHGL
IPPHPAALLAVQAYHADIGRTIAYGLIVGVPTAIVAGPLFALLIHRHIKLAANNPLAAQFIDTEHKEGTRDLPGFGITLF
TILLPVILMLVGSWADLVFAPKTTANDLLRFIGTSDVALLIAVLVSFWTFGAKRGFNREQIQKFCGDCLAPIAGITLIVG
AGGGFGRVLMDSGISKEIVATATAAHLSPLLFGWFVAALIRLATGSATVAMTTACGIVAPVAAASGVQVKPELLVLATGS
GSLIFSHVNDGGFWLIKEYFGMTVGQTFQTWSLCETIISLMGLGLTFALAAVL

Specific function: Transport Of Gluconate And L-Idonate. [C]

COG id: COG2610

COG function: function code GE; H+/gluconate symporter and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gntP permease family [H]

Homologues:

Organism=Escherichia coli, GI48994935, Length=436, Percent_Identity=43.8073394495413, Blast_Score=353, Evalue=2e-98,
Organism=Escherichia coli, GI1790716, Length=446, Percent_Identity=43.0493273542601, Blast_Score=352, Evalue=3e-98,
Organism=Escherichia coli, GI2367370, Length=441, Percent_Identity=40.3628117913832, Blast_Score=298, Evalue=4e-82,
Organism=Escherichia coli, GI1788707, Length=442, Percent_Identity=38.9140271493213, Blast_Score=294, Evalue=8e-81,
Organism=Escherichia coli, GI1790776, Length=439, Percent_Identity=33.7129840546697, Blast_Score=262, Evalue=3e-71,
Organism=Escherichia coli, GI48994939, Length=437, Percent_Identity=35.2402745995423, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI1789097, Length=453, Percent_Identity=34.4370860927152, Blast_Score=226, Evalue=2e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003474 [H]

Pfam domain/function: PF02447 GntP_permease [H]

EC number: NA

Molecular weight: Translated: 47596; Mature: 47596

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAVHGSMLLIYAVIAIAVLILMITRFKVYPFLVLIIVSLLLGLAVGMPAGTIVKSFETG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHEECC
NGNTLGHIAIVVGLGTMLGKMMAESGGAERVATTLINWFGEKNIHWAMMFVAIIVGLPVF
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
FEVGFVLLIPIAFNVAKRTGKSLLLIGLPMVAGLSVVHGLIPPHPAALLAVQAYHADIGR
HHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
TIAYGLIVGVPTAIVAGPLFALLIHRHIKLAANNPLAAQFIDTEHKEGTRDLPGFGITLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHCCCCCCCCCCCCCCCHHHHH
TILLPVILMLVGSWADLVFAPKTTANDLLRFIGTSDVALLIAVLVSFWTFGAKRGFNREQ
HHHHHHHHHHHCCHHHEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHH
IQKFCGDCLAPIAGITLIVGAGGGFGRVLMDSGISKEIVATATAAHLSPLLFGWFVAALI
HHHHHHHHHHHHHHHEEEEECCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RLATGSATVAMTTACGIVAPVAAASGVQVKPELLVLATGSGSLIFSHVNDGGFWLIKEYF
HHHCCCCHHHHHHHHHHHHHHHHCCCCEECCCEEEEEECCCCEEEEEECCCCEEEEHHHH
GMTVGQTFQTWSLCETIISLMGLGLTFALAAVL
CCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MEAVHGSMLLIYAVIAIAVLILMITRFKVYPFLVLIIVSLLLGLAVGMPAGTIVKSFETG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHEECC
NGNTLGHIAIVVGLGTMLGKMMAESGGAERVATTLINWFGEKNIHWAMMFVAIIVGLPVF
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
FEVGFVLLIPIAFNVAKRTGKSLLLIGLPMVAGLSVVHGLIPPHPAALLAVQAYHADIGR
HHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
TIAYGLIVGVPTAIVAGPLFALLIHRHIKLAANNPLAAQFIDTEHKEGTRDLPGFGITLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHCCCCCCCCCCCCCCCHHHHH
TILLPVILMLVGSWADLVFAPKTTANDLLRFIGTSDVALLIAVLVSFWTFGAKRGFNREQ
HHHHHHHHHHHCCHHHEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHH
IQKFCGDCLAPIAGITLIVGAGGGFGRVLMDSGISKEIVATATAAHLSPLLFGWFVAALI
HHHHHHHHHHHHHHHEEEEECCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RLATGSATVAMTTACGIVAPVAAASGVQVKPELLVLATGSGSLIFSHVNDGGFWLIKEYF
HHHCCCCHHHHHHHHHHHHHHHHCCCCEECCCEEEEEECCCCEEEEEECCCCEEEEHHHH
GMTVGQTFQTWSLCETIISLMGLGLTFALAAVL
CCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: gluconate [Periplasm]; Proton [Periplasm]; L-idonate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + gluconate [Periplasm] = Proton [Cytoplasm] + gluconate [Cytoplasm] Proton [Periplasm] + L-idonate [Periplasm] = L-idonate [Cytoplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA