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The map label for this gene is katA [H]

Identifier: 186477269

GI number: 186477269

Start: 2839437

End: 2840891

Strand: Reverse

Name: katA [H]

Synonym: Bphy_2521

Alternate gene names: 186477269

Gene position: 2840891-2839437 (Counterclockwise)

Preceding gene: 186477270

Following gene: 186477268

Centisome position: 81.65

GC content: 61.24

Gene sequence:

>1455_bases
ATGTCTGAACGCACCCTCACCACCGCTTCGGGCGCACCCGTCGCCGACAACCAGAATTCGCTGACGGCCGGCCCGCGCGG
CCCCGTCGCGCTGCAGGACGTGTGGCTGATCGAAAAACTCGCTCACTTCGACCGCGAAGTGATTCCCGAGCGTCGCGTTC
ACGCGAAGGGTTCGGGCGCGTTCGGCACCCTCAAGGTGACGCATGACATCTCGCGTTACACGAAGGCGAAGGTGTTCTCG
GAAGTGGGCAAGGAAACGCCGCTGTTCATGCGCTTCTCGACAGTGGCGGGTGAGCGCGGCGCGGCCGACGCCGAGCGCGA
CGTGCGCGGCTTCTCGATCAAGTTCTACACCGAAGAGGGCAACTGGGACGTCGTGGGCAATAACACGCCTGTGTTCTTCA
TCCGCGATCCGCTGAAGTTTCCCGACTTCATCCACACGCAAAAGCGTGATCCGTACACCAATATGCGCAGCGCGACGAAT
GCGTGGGATTTCTTCTCGCGTCACCCTGAGTCGCTGCATCAGGTGACGATCGTGATGAGCGATCGCGGCATTCCGAAGAA
CTACCGGCAGATGCATGGCTTCGGCTCGCACACGTTCTCGTTCATTAACGCGAATGACGAGCGCTTCTGGGTGAAGTTCC
ATTTCAAGTCGATGCAGGGTATCGAGAATTACACCGATGAAGAGGCCGCGCAAGTCGTCGCGCGTGACCGTGAAAGTGCG
CAGCGCGACCTCGTCGAGTCGATCGACGGCGGCCAGTTTCCGAAGTGGCACTTCCAGATTCAGGTGATGCCGGAACAGGA
TGCAGCGGTGTATCGCTACAACCCGTTCGATATCACGAAGGTCTGGCCGTACAAGGACTATCCGCTGATCGATGTCGGCG
TGATCGAGTTGAATCGCAATGCGCAGAATTACTTCGCGGATGTCGAGCAGGCCGCATTTACGCCGGCAAACGTAGTGCCC
GGCATTGGCTTCTCGCCGGACCGCCTGCTGCAAGGGCGCCTGTTCTCGTACGGTGACACGCAGCGCTATCGTCTCGGCGT
GAATCATCATCTGATTCCCGTGAACGCGTCGCGCGCATCGAACGTGCGCTCGTTCCATCGCGACGGCGGCATGCGCGTCG
ACGGCAATCTTGGCGGCAGCGTGAACTACGAGCCGAACCGTTTCGGCGACTTCGCGCAGGACCGTAACGCGATCGAGCCG
CCGCTCGCGGCAGGCAACGTCGGTCACTACAACCATCGCGAAGACGACGATTACTACAGCCAGCCGGCGGCGCTGTTCCG
CATTTTCGACAGCGCACAGCGCGAACGTCTGTTCGGCAACATCGCGCGAGCGATCGACGGCGTGCCCGCCGATATCGTCG
CGCGACAGATCGAGCACTTCCGCAAGATCGATCCGGCGTATGCCGACGGCGTGATCGCTGCCATCGAGGCGCTCGCGAAA
GCGAAGGCGAAGTAG

Upstream 100 bases:

>100_bases
TACTCGTCGATCGCGCGCTGTCCGCCTGATCGCGCTCCCGCTGTTCACCGAATCCATCGCACGCTACGACGGCAACTCAA
GCATCATCCGGAGAAGAACT

Downstream 100 bases:

>100_bases
CATTTCGGCTTGCAGACGGCGCATGCGCCGTCTGCTCCGGCAAGCAACGAGTACAGGACGACGCGATGCCCTCCTGTCGG
CAAAGGAGAAAGATCATGGT

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MSERTLTTASGAPVADNQNSLTAGPRGPVALQDVWLIEKLAHFDREVIPERRVHAKGSGAFGTLKVTHDISRYTKAKVFS
EVGKETPLFMRFSTVAGERGAADAERDVRGFSIKFYTEEGNWDVVGNNTPVFFIRDPLKFPDFIHTQKRDPYTNMRSATN
AWDFFSRHPESLHQVTIVMSDRGIPKNYRQMHGFGSHTFSFINANDERFWVKFHFKSMQGIENYTDEEAAQVVARDRESA
QRDLVESIDGGQFPKWHFQIQVMPEQDAAVYRYNPFDITKVWPYKDYPLIDVGVIELNRNAQNYFADVEQAAFTPANVVP
GIGFSPDRLLQGRLFSYGDTQRYRLGVNHHLIPVNASRASNVRSFHRDGGMRVDGNLGGSVNYEPNRFGDFAQDRNAIEP
PLAAGNVGHYNHREDDDYYSQPAALFRIFDSAQRERLFGNIARAIDGVPADIVARQIEHFRKIDPAYADGVIAAIEALAK
AKAK

Sequences:

>Translated_484_residues
MSERTLTTASGAPVADNQNSLTAGPRGPVALQDVWLIEKLAHFDREVIPERRVHAKGSGAFGTLKVTHDISRYTKAKVFS
EVGKETPLFMRFSTVAGERGAADAERDVRGFSIKFYTEEGNWDVVGNNTPVFFIRDPLKFPDFIHTQKRDPYTNMRSATN
AWDFFSRHPESLHQVTIVMSDRGIPKNYRQMHGFGSHTFSFINANDERFWVKFHFKSMQGIENYTDEEAAQVVARDRESA
QRDLVESIDGGQFPKWHFQIQVMPEQDAAVYRYNPFDITKVWPYKDYPLIDVGVIELNRNAQNYFADVEQAAFTPANVVP
GIGFSPDRLLQGRLFSYGDTQRYRLGVNHHLIPVNASRASNVRSFHRDGGMRVDGNLGGSVNYEPNRFGDFAQDRNAIEP
PLAAGNVGHYNHREDDDYYSQPAALFRIFDSAQRERLFGNIARAIDGVPADIVARQIEHFRKIDPAYADGVIAAIEALAK
AKAK
>Mature_483_residues
SERTLTTASGAPVADNQNSLTAGPRGPVALQDVWLIEKLAHFDREVIPERRVHAKGSGAFGTLKVTHDISRYTKAKVFSE
VGKETPLFMRFSTVAGERGAADAERDVRGFSIKFYTEEGNWDVVGNNTPVFFIRDPLKFPDFIHTQKRDPYTNMRSATNA
WDFFSRHPESLHQVTIVMSDRGIPKNYRQMHGFGSHTFSFINANDERFWVKFHFKSMQGIENYTDEEAAQVVARDRESAQ
RDLVESIDGGQFPKWHFQIQVMPEQDAAVYRYNPFDITKVWPYKDYPLIDVGVIELNRNAQNYFADVEQAAFTPANVVPG
IGFSPDRLLQGRLFSYGDTQRYRLGVNHHLIPVNASRASNVRSFHRDGGMRVDGNLGGSVNYEPNRFGDFAQDRNAIEPP
LAAGNVGHYNHREDDDYYSQPAALFRIFDSAQRERLFGNIARAIDGVPADIVARQIEHFRKIDPAYADGVIAAIEALAKA
KAK

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=481, Percent_Identity=50.9355509355509, Blast_Score=504, Evalue=1e-143,
Organism=Escherichia coli, GI48994891, Length=390, Percent_Identity=48.4615384615385, Blast_Score=355, Evalue=3e-99,
Organism=Caenorhabditis elegans, GI71998444, Length=481, Percent_Identity=49.8960498960499, Blast_Score=485, Evalue=1e-137,
Organism=Caenorhabditis elegans, GI25147792, Length=470, Percent_Identity=48.7234042553191, Blast_Score=465, Evalue=1e-131,
Organism=Caenorhabditis elegans, GI25151141, Length=468, Percent_Identity=48.9316239316239, Blast_Score=465, Evalue=1e-131,
Organism=Saccharomyces cerevisiae, GI6320462, Length=492, Percent_Identity=45.1219512195122, Blast_Score=392, Evalue=1e-109,
Organism=Saccharomyces cerevisiae, GI6321525, Length=404, Percent_Identity=40.5940594059406, Blast_Score=310, Evalue=2e-85,
Organism=Drosophila melanogaster, GI17981717, Length=487, Percent_Identity=48.0492813141684, Blast_Score=466, Evalue=1e-131,
Organism=Drosophila melanogaster, GI19920968, Length=485, Percent_Identity=44.7422680412371, Blast_Score=437, Evalue=1e-122,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 54700; Mature: 54568

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERTLTTASGAPVADNQNSLTAGPRGPVALQDVWLIEKLAHFDREVIPERRVHAKGSGA
CCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCC
FGTLKVTHDISRYTKAKVFSEVGKETPLFMRFSTVAGERGAADAERDVRGFSIKFYTEEG
EEEEEEEHHHHHHHHHHHHHHHCCCCCEEEEEEHHCCCCCCCCCHHCCCEEEEEEEEECC
NWDVVGNNTPVFFIRDPLKFPDFIHTQKRDPYTNMRSATNAWDFFSRHPESLHQVTIVMS
CEEEECCCCCEEEEECCCCCCHHHHCCCCCCCHHHHHHCCHHHHHHCCCCCCEEEEEEEE
DRGIPKNYRQMHGFGSHTFSFINANDERFWVKFHFKSMQGIENYTDEEAAQVVARDRESA
CCCCCHHHHHHCCCCCCEEEEEECCCCEEEEEEEECHHCCHHCCCHHHHHHHHHHHHHHH
QRDLVESIDGGQFPKWHFQIQVMPEQDAAVYRYNPFDITKVWPYKDYPLIDVGVIELNRN
HHHHHHHCCCCCCCCEEEEEEEECCCCCEEEEECCCCCEEECCCCCCCEEEEEEEEECCC
AQNYFADVEQAAFTPANVVPGIGFSPDRLLQGRLFSYGDTQRYRLGVNHHLIPVNASRAS
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCHHHCCCCCCEEEECCCEEEEEECCCHHH
NVRSFHRDGGMRVDGNLGGSVNYEPNRFGDFAQDRNAIEPPLAAGNVGHYNHREDDDYYS
HHHHHHHCCCEEECCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCHHHH
QPAALFRIFDSAQRERLFGNIARAIDGVPADIVARQIEHFRKIDPAYADGVIAAIEALAK
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AKAK
HCCC
>Mature Secondary Structure 
SERTLTTASGAPVADNQNSLTAGPRGPVALQDVWLIEKLAHFDREVIPERRVHAKGSGA
CCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCC
FGTLKVTHDISRYTKAKVFSEVGKETPLFMRFSTVAGERGAADAERDVRGFSIKFYTEEG
EEEEEEEHHHHHHHHHHHHHHHCCCCCEEEEEEHHCCCCCCCCCHHCCCEEEEEEEEECC
NWDVVGNNTPVFFIRDPLKFPDFIHTQKRDPYTNMRSATNAWDFFSRHPESLHQVTIVMS
CEEEECCCCCEEEEECCCCCCHHHHCCCCCCCHHHHHHCCHHHHHHCCCCCCEEEEEEEE
DRGIPKNYRQMHGFGSHTFSFINANDERFWVKFHFKSMQGIENYTDEEAAQVVARDRESA
CCCCCHHHHHHCCCCCCEEEEEECCCCEEEEEEEECHHCCHHCCCHHHHHHHHHHHHHHH
QRDLVESIDGGQFPKWHFQIQVMPEQDAAVYRYNPFDITKVWPYKDYPLIDVGVIELNRN
HHHHHHHCCCCCCCCEEEEEEEECCCCCEEEEECCCCCEEECCCCCCCEEEEEEEEECCC
AQNYFADVEQAAFTPANVVPGIGFSPDRLLQGRLFSYGDTQRYRLGVNHHLIPVNASRAS
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCHHHCCCCCCEEEECCCEEEEEECCCHHH
NVRSFHRDGGMRVDGNLGGSVNYEPNRFGDFAQDRNAIEPPLAAGNVGHYNHREDDDYYS
HHHHHHHCCCEEECCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCHHHH
QPAALFRIFDSAQRERLFGNIARAIDGVPADIVARQIEHFRKIDPAYADGVIAAIEALAK
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AKAK
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]